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BILWADI AGADA
BY
DR. KOMAL M. JADHAV
1ST YEAR PG SCHOLAR
DEPT. OF AGADATANTRA
09-08-2021
BILWADI AGAD 1
09-08-2021
BILWADI AGAD 2
CONTENTS
INTRODUCTION
OBJECTIVES
SHLOKA
INGREDIENTS
METHOD OF PREPARATION
RASAPANCHAK
INDICATIONS
MODE OF USAGE
QUALITY TESTS
RESEARCH WORKS
REFERENCES
MARKET AVAILABILITY
09-08-2021
BILWADI AGAD 3
INTRODUCTION
 Bilwadi agada
 Bilwadi gutika is also called as vilwadi agada, vilwadi vati.
 Bilwadi agada is explained in sahasrayoga, kriyakaumudi,
vishajoshnika, astanga sangraha and astanga hruday.
 It is a herbal preparation.
 It is explained under sarpa visha pratished adhyaya.
09-08-2021
BILWADI AGAD 4
OBJECTIVES
• To know in detail about bilwadi agada, its application and mode of
action.
09-08-2021
BILWADI AGAD 5
SHLOKA
09-08-2021
BILWADI AGAD 6
INGREDIENTS WITH QUANTITY
BILVA - 1 PART
SURASA (TULSI) - 1 PART
KARANJA - 1 PART
NATA (TAGARA ) - 1 PART
SURAVAHA (DEVADARU)- 1 PART
HARITAKI - 1 PART
BIBHITAKI - 1 PART
AMALAKI - 1 PART
SUNTHI - 1 PART
MARICHA - 1PART
PIPPALI - 1 PART
HARIDRA - 1 PART
DARUHARIDRA - 1 PART
BASTHAMUTRA - Q.S
09-08-2021
BILWADI AGAD 7
METHOD OF PREPARATION
take the above mentioned ingredients in equal quantities.
grind each ingredient separately to make fine powder.
make a homogeneous mixture of above ingredients and macerate the
compound with basta mutra.
make it into tablet form.
09-08-2021
BILWADI AGAD 8
RASA PANCHAK
09-08-2021
BILWADI AGAD
9
09-08-2021
BILWADI AGAD 10
DRUG
BOTONICAL NAME PART USED PHARMACOLOGICAL ACTION
Bilwa Aegle marmelos root Anti- diarrheal, antimicrobial, anti-inflammatory
Surasa Ocimum sanctum flower Anti-toxic, anti-microbial, anti-inflammatory
Karanja Pongamia pinnata fruit Antibiotic, anti-fungal
Nata Valeriana wallichi root Anti convulsant, sedative
suravaha Cedrus deodara Anti-inflammatory, analgesic
haritaki Terminalia chebula fruit antimicrobial, anti-viral, anti-fungal
bibhitaki Terminalia bel-lerica fruit Anti-oxidant, analgesic, anti-spasmodic
aamalaki Embelica officinale fruit Anti-oxidant
shunti Zingiber officinale Rhizome anti-oxidant, anti-inflammatory
maricha Piper nigrum fruit Anti-inflammatory, anti- diarrheal, anti-inflammatory
pippali Piper longa fruit Anti- helminthic
haridra Curcuma longum Rhizome Anti-oxidant, anti-inflammatory
daruharidra Berberis aristata Rhizome Anti-oxidant, anti-pyretic, anti-hepatotoxic
INDICATION
Snake bites
Scorpion bite
Spider bite
Visuchika
Jwara
Gara visha
Ajeerna
Bhuta bada 09-08-2021
BILWADI AGAD
11
09-08-2021
BILWADI AGAD 12
09-08-2021
BILWADI AGAD 13
09-08-2021
BILWADI AGAD 14
MODE OF USAGE
Anjana
Nasya
Pana
09-08-2021
BILWADI AGAD 15
QUALITY TESTS
• Physicochemical analysis.
• TLC and HPTLC
• Microbial limit test.
09-08-2021
BILWADI AGAD 16
RESEARCH WORK
• An experimental evaluation of effect of bilwadi agada in isoniazid and rifampicin combination
induced hepatotoxicity .
(bilwadi agada showed significant improvement in SGOT and SGPT and histopathological analysis
showed hepatocyte regeneration effect.)
• Evaluation of hepatoprotective activity of bilwadi agada against methotrexate induced
hepatotoxicity-an experimental study.
(Bilwadi agada showed significant improvement in SGOT, SGPT, ALP, bilirubin levels and in
histopathological analysis)
09-08-2021
BILWADI AGAD 17
• Evaluation of antifungal activity of aqueous and alcoholic extract of bilwadi agada against some
fungal strains.(Alcoholic extract of bilwadi agada shown better result in comparison with aqueous
extract).
• In-vitro evaluation of Bilwadi Agada (herbo – mineral compound) for anti-microbial and
antifungal activity (it exhibited moderate to mild anti-microbial activity against most of the
tested bacteria ( bacillus subtilis, E coli, Styphylococcus aureus, S paratyphi) and fungi (Candidia
albicans, Aspergillus niger) )
• Role of bilwadi agada in prevention of COVID – 19.
• Role of Bilwadi agada in the management of scorpion sting – clinical study
(It showed significant result in reducing pain, burning sensation, itching, erythema, inflammation
etc.) 09-08-2021
BILWADI AGAD 18
ACTION
• Maximum drugs having Katu, tikta rasa Pradhan.
• Tikta rasa- Vishagna,
• All drugs having Deepana, Pachana and Vishagna property.
• Most drugs are Ushna virya and Katu Vipaka hence it can act as antidote.
• Maximum drugs having Vaata- Kaphagna property.
• As per the previous studies bilwadi agada having the property of anti-
inflammatory, analgesic, anti-oxidant, antibiotic and also useful in conditions
like gastroenteritis.
09-08-2021
BILWADI AGAD 19
MARKET AVAILABILITY
o Nagarjuna pharma – 100 tabs – 325rs
o Ayushcare – 50 tabs – 96rs
o Kle pharmacy-50 tabs-100rs
o Vaidyaratnam pharmacy-50tabs-15rs
09-08-2021
BILWADI AGAD 20
09-08-2021
BILWADI AGAD 21
• Bilwadi choorna is different from Bilwadi agada.
• Bilwadi churna contains mocharasa, dhania, sabj patra,
dhai phool, bel giri, sounth.
09-08-2021
BILWADI AGAD 22
REFERENCES
• Astanga hruday Uttartantra 36/84-85.
• Kamal G C, Gururaj C H, A review on Bilwadi Agada and its indications. world journal
of pharmacy and pharmaceutical sciences.2021;10(3):338-347
• Binorkar S,
• Parlikar G, Ukey R N, Nirgude R, In-vitro evaluation of bilwadi agada (herbo-mineral
compound)for anti-microbial and anti-fungal activity. Journal of Biological and
Scientific Opinion.2013;1(2)
• Rajpuria v, James a, Role of Bilwadi Agada in prevention of covid-19. International
ayurvedic medical journal;2020:3939-3944
• Binorkar S, C M Srikrishanan, K V Asha, Role of Bilwadi Agada in the management of
scorpion sting;IJRAP;2013: 4(1);59-63
09-08-2021
BILWADI AGAD 23
09-08-2021
BILWADI AGAD 24

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BILWADI AGAD.pptx

  • 1. BILWADI AGADA BY DR. KOMAL M. JADHAV 1ST YEAR PG SCHOLAR DEPT. OF AGADATANTRA 09-08-2021 BILWADI AGAD 1
  • 3. CONTENTS INTRODUCTION OBJECTIVES SHLOKA INGREDIENTS METHOD OF PREPARATION RASAPANCHAK INDICATIONS MODE OF USAGE QUALITY TESTS RESEARCH WORKS REFERENCES MARKET AVAILABILITY 09-08-2021 BILWADI AGAD 3
  • 4. INTRODUCTION  Bilwadi agada  Bilwadi gutika is also called as vilwadi agada, vilwadi vati.  Bilwadi agada is explained in sahasrayoga, kriyakaumudi, vishajoshnika, astanga sangraha and astanga hruday.  It is a herbal preparation.  It is explained under sarpa visha pratished adhyaya. 09-08-2021 BILWADI AGAD 4
  • 5. OBJECTIVES • To know in detail about bilwadi agada, its application and mode of action. 09-08-2021 BILWADI AGAD 5
  • 7. INGREDIENTS WITH QUANTITY BILVA - 1 PART SURASA (TULSI) - 1 PART KARANJA - 1 PART NATA (TAGARA ) - 1 PART SURAVAHA (DEVADARU)- 1 PART HARITAKI - 1 PART BIBHITAKI - 1 PART AMALAKI - 1 PART SUNTHI - 1 PART MARICHA - 1PART PIPPALI - 1 PART HARIDRA - 1 PART DARUHARIDRA - 1 PART BASTHAMUTRA - Q.S 09-08-2021 BILWADI AGAD 7
  • 8. METHOD OF PREPARATION take the above mentioned ingredients in equal quantities. grind each ingredient separately to make fine powder. make a homogeneous mixture of above ingredients and macerate the compound with basta mutra. make it into tablet form. 09-08-2021 BILWADI AGAD 8
  • 10. 09-08-2021 BILWADI AGAD 10 DRUG BOTONICAL NAME PART USED PHARMACOLOGICAL ACTION Bilwa Aegle marmelos root Anti- diarrheal, antimicrobial, anti-inflammatory Surasa Ocimum sanctum flower Anti-toxic, anti-microbial, anti-inflammatory Karanja Pongamia pinnata fruit Antibiotic, anti-fungal Nata Valeriana wallichi root Anti convulsant, sedative suravaha Cedrus deodara Anti-inflammatory, analgesic haritaki Terminalia chebula fruit antimicrobial, anti-viral, anti-fungal bibhitaki Terminalia bel-lerica fruit Anti-oxidant, analgesic, anti-spasmodic aamalaki Embelica officinale fruit Anti-oxidant shunti Zingiber officinale Rhizome anti-oxidant, anti-inflammatory maricha Piper nigrum fruit Anti-inflammatory, anti- diarrheal, anti-inflammatory pippali Piper longa fruit Anti- helminthic haridra Curcuma longum Rhizome Anti-oxidant, anti-inflammatory daruharidra Berberis aristata Rhizome Anti-oxidant, anti-pyretic, anti-hepatotoxic
  • 11. INDICATION Snake bites Scorpion bite Spider bite Visuchika Jwara Gara visha Ajeerna Bhuta bada 09-08-2021 BILWADI AGAD 11
  • 16. QUALITY TESTS • Physicochemical analysis. • TLC and HPTLC • Microbial limit test. 09-08-2021 BILWADI AGAD 16
  • 17. RESEARCH WORK • An experimental evaluation of effect of bilwadi agada in isoniazid and rifampicin combination induced hepatotoxicity . (bilwadi agada showed significant improvement in SGOT and SGPT and histopathological analysis showed hepatocyte regeneration effect.) • Evaluation of hepatoprotective activity of bilwadi agada against methotrexate induced hepatotoxicity-an experimental study. (Bilwadi agada showed significant improvement in SGOT, SGPT, ALP, bilirubin levels and in histopathological analysis) 09-08-2021 BILWADI AGAD 17
  • 18. • Evaluation of antifungal activity of aqueous and alcoholic extract of bilwadi agada against some fungal strains.(Alcoholic extract of bilwadi agada shown better result in comparison with aqueous extract). • In-vitro evaluation of Bilwadi Agada (herbo – mineral compound) for anti-microbial and antifungal activity (it exhibited moderate to mild anti-microbial activity against most of the tested bacteria ( bacillus subtilis, E coli, Styphylococcus aureus, S paratyphi) and fungi (Candidia albicans, Aspergillus niger) ) • Role of bilwadi agada in prevention of COVID – 19. • Role of Bilwadi agada in the management of scorpion sting – clinical study (It showed significant result in reducing pain, burning sensation, itching, erythema, inflammation etc.) 09-08-2021 BILWADI AGAD 18
  • 19. ACTION • Maximum drugs having Katu, tikta rasa Pradhan. • Tikta rasa- Vishagna, • All drugs having Deepana, Pachana and Vishagna property. • Most drugs are Ushna virya and Katu Vipaka hence it can act as antidote. • Maximum drugs having Vaata- Kaphagna property. • As per the previous studies bilwadi agada having the property of anti- inflammatory, analgesic, anti-oxidant, antibiotic and also useful in conditions like gastroenteritis. 09-08-2021 BILWADI AGAD 19
  • 20. MARKET AVAILABILITY o Nagarjuna pharma – 100 tabs – 325rs o Ayushcare – 50 tabs – 96rs o Kle pharmacy-50 tabs-100rs o Vaidyaratnam pharmacy-50tabs-15rs 09-08-2021 BILWADI AGAD 20
  • 22. • Bilwadi choorna is different from Bilwadi agada. • Bilwadi churna contains mocharasa, dhania, sabj patra, dhai phool, bel giri, sounth. 09-08-2021 BILWADI AGAD 22
  • 23. REFERENCES • Astanga hruday Uttartantra 36/84-85. • Kamal G C, Gururaj C H, A review on Bilwadi Agada and its indications. world journal of pharmacy and pharmaceutical sciences.2021;10(3):338-347 • Binorkar S, • Parlikar G, Ukey R N, Nirgude R, In-vitro evaluation of bilwadi agada (herbo-mineral compound)for anti-microbial and anti-fungal activity. Journal of Biological and Scientific Opinion.2013;1(2) • Rajpuria v, James a, Role of Bilwadi Agada in prevention of covid-19. International ayurvedic medical journal;2020:3939-3944 • Binorkar S, C M Srikrishanan, K V Asha, Role of Bilwadi Agada in the management of scorpion sting;IJRAP;2013: 4(1);59-63 09-08-2021 BILWADI AGAD 23