This document describes Bilwadi Agada, an Ayurvedic herbal formulation used to treat snake bites, scorpion bites, and other conditions. It contains 12 herbs including Bilva, Tulsi, Karanja, and Haritaki. The ingredients have anti-toxic, anti-inflammatory, and antimicrobial properties. Research shows Bilwadi Agada protects the liver from toxicity and has antifungal effects. It is used as an eye/nose drops or taken orally to treat various poisonings and fever.

1. BILWADI AGADA
BY
DR. KOMAL M. JADHAV
1ST YEAR PG SCHOLAR
DEPT. OF AGADATANTRA
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3. CONTENTS
INTRODUCTION
OBJECTIVES
SHLOKA
INGREDIENTS
METHOD OF PREPARATION
RASAPANCHAK
INDICATIONS
MODE OF USAGE
QUALITY TESTS
RESEARCH WORKS
REFERENCES
MARKET AVAILABILITY
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4. INTRODUCTION
 Bilwadi agada
 Bilwadi gutika is also called as vilwadi agada, vilwadi vati.
 Bilwadi agada is explained in sahasrayoga, kriyakaumudi,
vishajoshnika, astanga sangraha and astanga hruday.
 It is a herbal preparation.
 It is explained under sarpa visha pratished adhyaya.
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5. OBJECTIVES
• To know in detail about bilwadi agada, its application and mode of
action.
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6. SHLOKA
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7. INGREDIENTS WITH QUANTITY
BILVA - 1 PART
SURASA (TULSI) - 1 PART
KARANJA - 1 PART
NATA (TAGARA ) - 1 PART
SURAVAHA (DEVADARU)- 1 PART
HARITAKI - 1 PART
BIBHITAKI - 1 PART
AMALAKI - 1 PART
SUNTHI - 1 PART
MARICHA - 1PART
PIPPALI - 1 PART
HARIDRA - 1 PART
DARUHARIDRA - 1 PART
BASTHAMUTRA - Q.S
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8. METHOD OF PREPARATION
take the above mentioned ingredients in equal quantities.
grind each ingredient separately to make fine powder.
make a homogeneous mixture of above ingredients and macerate the
compound with basta mutra.
make it into tablet form.
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9. RASA PANCHAK
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DRUG
BOTONICAL NAME PART USED PHARMACOLOGICAL ACTION
Bilwa Aegle marmelos root Anti- diarrheal, antimicrobial, anti-inflammatory
Surasa Ocimum sanctum flower Anti-toxic, anti-microbial, anti-inflammatory
Karanja Pongamia pinnata fruit Antibiotic, anti-fungal
Nata Valeriana wallichi root Anti convulsant, sedative
suravaha Cedrus deodara Anti-inflammatory, analgesic
haritaki Terminalia chebula fruit antimicrobial, anti-viral, anti-fungal
bibhitaki Terminalia bel-lerica fruit Anti-oxidant, analgesic, anti-spasmodic
aamalaki Embelica officinale fruit Anti-oxidant
shunti Zingiber officinale Rhizome anti-oxidant, anti-inflammatory
maricha Piper nigrum fruit Anti-inflammatory, anti- diarrheal, anti-inflammatory
pippali Piper longa fruit Anti- helminthic
haridra Curcuma longum Rhizome Anti-oxidant, anti-inflammatory
daruharidra Berberis aristata Rhizome Anti-oxidant, anti-pyretic, anti-hepatotoxic

11. INDICATION
Snake bites
Scorpion bite
Spider bite
Visuchika
Jwara
Gara visha
Ajeerna
Bhuta bada 09-08-2021
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15. MODE OF USAGE
Anjana
Nasya
Pana
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16. QUALITY TESTS
• Physicochemical analysis.
• TLC and HPTLC
• Microbial limit test.
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17. RESEARCH WORK
• An experimental evaluation of effect of bilwadi agada in isoniazid and rifampicin combination
induced hepatotoxicity .
(bilwadi agada showed significant improvement in SGOT and SGPT and histopathological analysis
showed hepatocyte regeneration effect.)
• Evaluation of hepatoprotective activity of bilwadi agada against methotrexate induced
hepatotoxicity-an experimental study.
(Bilwadi agada showed significant improvement in SGOT, SGPT, ALP, bilirubin levels and in
histopathological analysis)
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18. • Evaluation of antifungal activity of aqueous and alcoholic extract of bilwadi agada against some
fungal strains.(Alcoholic extract of bilwadi agada shown better result in comparison with aqueous
extract).
• In-vitro evaluation of Bilwadi Agada (herbo – mineral compound) for anti-microbial and
antifungal activity (it exhibited moderate to mild anti-microbial activity against most of the
tested bacteria ( bacillus subtilis, E coli, Styphylococcus aureus, S paratyphi) and fungi (Candidia
albicans, Aspergillus niger) )
• Role of bilwadi agada in prevention of COVID – 19.
• Role of Bilwadi agada in the management of scorpion sting – clinical study
(It showed significant result in reducing pain, burning sensation, itching, erythema, inflammation
etc.) 09-08-2021
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19. ACTION
• Maximum drugs having Katu, tikta rasa Pradhan.
• Tikta rasa- Vishagna,
• All drugs having Deepana, Pachana and Vishagna property.
• Most drugs are Ushna virya and Katu Vipaka hence it can act as antidote.
• Maximum drugs having Vaata- Kaphagna property.
• As per the previous studies bilwadi agada having the property of anti-
inflammatory, analgesic, anti-oxidant, antibiotic and also useful in conditions
like gastroenteritis.
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20. MARKET AVAILABILITY
o Nagarjuna pharma – 100 tabs – 325rs
o Ayushcare – 50 tabs – 96rs
o Kle pharmacy-50 tabs-100rs
o Vaidyaratnam pharmacy-50tabs-15rs
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22. • Bilwadi choorna is different from Bilwadi agada.
• Bilwadi churna contains mocharasa, dhania, sabj patra,
dhai phool, bel giri, sounth.
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23. REFERENCES
• Astanga hruday Uttartantra 36/84-85.
• Kamal G C, Gururaj C H, A review on Bilwadi Agada and its indications. world journal
of pharmacy and pharmaceutical sciences.2021;10(3):338-347
• Binorkar S,
• Parlikar G, Ukey R N, Nirgude R, In-vitro evaluation of bilwadi agada (herbo-mineral
compound)for anti-microbial and anti-fungal activity. Journal of Biological and
Scientific Opinion.2013;1(2)
• Rajpuria v, James a, Role of Bilwadi Agada in prevention of covid-19. International
ayurvedic medical journal;2020:3939-3944
• Binorkar S, C M Srikrishanan, K V Asha, Role of Bilwadi Agada in the management of
scorpion sting;IJRAP;2013: 4(1);59-63
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