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13/21/2015
Outline
Modification of beam
Need of beam modification
Types of beam modification
Devices modifying the beam geometry
Working of beam modifiers
Beam modification
• Defined as desirable modification in the
spatial distribution of radiation - within the
patient - by insertion of any material in the
beam path
Four types of beam modification
• Shielding:
– To eliminate radiation dose to some special parts of
the zone at which the beam is directed
• Compensation:
– To allow normal dose distribution data to be applied
to the treated zone where different types of tissues
are present
• Wedge filtration:
– Where a special tilt in isodose curves is obtained
• Flattening:
– Where the spatial distribution of the natural beam is
altered by reducing the central exposure rate relative
to the peripheral
Beam modification devices
4 main types of beam modifying devices
Wedge filter
Compensator
Bolus
Shielding blocks
other modification devices
Beam spoilers
Beam flattening filters
Breast cone
Penumbra trimmers
Electron beam modification
Hurdles
• Radiation reaching any point, is made
up of primary and scattered photons.
• introduction of the modification devices
results in alteration of dose distribution
• The phenomena scattering results in an
“blurring” of the effect of the beam
modification
 The higher scatter
contribution to the
overall dose results in
lower dosage adjacent
to the shielded area in
kilovoltage radiation.
 Lesser amount of
scattered radiation with
megavoltage radiation
means that the
attenuation produced by
shielding is also more.
Shielding
to protect the critical structures around the treated
volume by using various devices
• The aims of shielding are:
To protect critical organs
Avoid unnecessary irradiation to surrounding normal tissue
Matching adjacent fields
• It should have following characteristics
high atomic number
high density
easily available
inexpensive
Shielding
Shielding Blocks
Independent Jaws
Multi Leaf Collimators
Custom Blocks
Lead as a shielding material
• Choice of shielding is also dictated by the type
of beam being used.
 It’s thickness depends on
• Attenuation of shielding material
– Half-value layer is defined as the thickness of an
absorber required to attenuate the intensity of beam
to half its original value.
• For practical purposes, the shielding material
which reduces beam transmission to 5% of its
original is considered acceptable
• The number of HVL (n)
1/2n = 5% or 0.05
Thus, 2n = 1/0.05 = 20 .OR, n log 2 = log 20.
n = 4.32
Placing of Shielding
 In Kilovoltage radiation shielding is readily achieved by
placing sheets of lead on the surface directly
It is necessary because of the lower penetrating power of beam
 In Megavoltage radiation,
– Thicker blocks used.
– Placed higher up in shadow trays (15 -20 cm).
– Avoids increase in skin dose due to electron scatter.
– Also impossible to place the heavy block on the body
Customised blocks
• Material used for custom locking is known as
the Wood's metal (Cerrobend)
• Commercial names
 Lipowitz's alloy
 Cerrobend,
 Bendalloy,
 Pewtalloy
 MCP 158
• Melting point 70°C.
• Density 9.4 g /cm3 at 20°C (83% of lead)
Composition Of Cerrobend
Lead, 26.70%
Bismuth, 50.00%Cadmium,
10.00%
Tin, 13.30%
Bismuth Lead Tin Cadmium
• Major advantage over lead is its low melting
point which enables it to cast in any shape.
• At room temperature it is harder than lead.
• 1.21 times thicker blocks necessary to
produce the same attenuation.
• Most commonly thickness of 7.5 cms used.
Construction of blocks
Outline of the treatment
field being traced on
radiograph using a
Styrofoam cutting
device.
Electrically heated wire
pivoting around a point
(simulating the source)
cutting the styrofoam block
Cavities in the
styrofoam block
being used to cast
the Cerrobend
blocks.
Custom blocks
 Shielding blocks can be of two types:
• Positive blocks,
where central area is blocked
• Negative blocks
where peripheral area is blocked
 Diverging Block
– Ideally blocks should be shaped or tapered so
that their sides follow the geometric
divergence which minimizes the block
transmission penumbra
Independent Jaws
 Used when we want to block
of the part of the field without
changing the position of the
isocenter
 Independently movable jaws,
allows us to shield a part of the
field & can be used for “beam
splitting”
 Beam is blocked off at the
central axis to remove the
divergence
 Use of independent jaws
results in the shift of the
isodose curves & penumbra
 This is due to the elimination
of photon and electrons scatter
from the blocked part
Multileaf collimators
• Multileaf collimators are a
bank of large number of
collimating blocks or leaves
• Can be moved
automatically independent
of each other to generate a
field of any shape.
• MLCs are available from all
the major medical LINAC
manufacturers : Elekta,
Siemens & Varian
• Independent
manufacturers:BrainLab,
Radionics, Direx,
NOMOS,Novalis
MLC
Conventional
Secondary Tertiary
Singly Focused
Doubly Focused
OR
Mini Micro
Single Plane
Double Plane
OR
Miniature
Intraleaf transmission:
radiation transmitted through the full height of the leaf
Interleaf transmission:
transmitted radiation measured along a line passing between leaf sides
Leaf end transmission:
transmitted radiation measured along a ray passing between the ends of
opposed leaves in their most closed position
Leaf Terminology
 Secondary MLC: replaces one of the
secondary jaws (upper or lower) - Elekta &
Siemens
 Tertiary MLC: add-on device in the head of
linac below the jaw collimators - Varian
 Leaves
– Elekta (80, microSRS )
– Siemens (58 and 80 leaves)
– Varian (52, 80 and 120 leaves)
ELEKTA MLC: Y-Jaw replacement
No. of leaves 80
Material Tungsten
Thickness (height) 7.5 cm
Arrangement Tongue and Groove
Width at isocentre 1.0 cm
Movement path Linear
End design Curved/rounded
Focusing Single
Interdigitization of opposite leaves Possible
Position Sensor Optical/CCD camera
Back-up jaw thickness 3.0 cm
Field size at isocentre 40 x 40 cm2
SIEMENS MLC:X-Jaw Replacement
No. of leaves 58
Field size at isocentre 40 x 40 cm2
Material Tungsten
Thickness (height) 7.6 cm
Arrangement Tongue and Groove
Width at isocentre 1.0 cm – inner 27 pairs
6.5 cm – outer 2 pairs
Movement path Circular arc
End design Straight
Focusing Double
Interdigitization Not Possible
Position Sensor Linear encoders
VARIAN MLC: Tertiary
Material Tungsten
Thickness (height) 5.0 cm
Arrangement Tongue and Groove
Movement path Linear
End design Curved/rounded
Focusing Single
Interdigitization Possible
Position Sensor Linear encoders
Comparison of leaf assembly
(End-on view)
Elekta Varian Siemens
 Merits
• beam shaping is simple and less time consuming
• these can be used without needing to enter treatment
room
• correction and changing of field shape is simple
• overall treatment time is shortened
• constant control and continuous adjustment of the
field shape during irradiation is possible
 Demerits
• step edge effect
• radiation leakage between the leaves
• wider penumbra
Tissue compensators
• Beam modifying device which evens out the skin
surface contours, while retaining the skin-sparing
advantage
• It allows normal depth dose data to be used for such
irregular surfaces.
• Compensators can also be used for
To compensate for tissue heterogeneity.
To compensate for dose irregularities arising due to
reduced scatter near the field edges.
• The dimension and shape of a compensator
must be adjusted to account for :
– Beam divergence.
– Linear attenuation coefficients of the filter
material and soft tissue
– Reduction in scatter at various depths due to the
compensating filters, when it is placed at the
distance away from the skin
• To compensate for these factors a tissue
compensator is always has an attenuation
less than that required for primary radiation
Thickness ratio or density ratio
Required thickness of a
tissue equivalent
compensator
Missing tissue thickness
along same ray
• The thickness ratio depends on:
– Compensator to surface distance,d
– Thickness of the missing tissue
– Field size
– Depth
– Beam quality
• Distance is the most important factor when d
is ≤ 20 cm
• A fixed value of thickness ratio (τ) is used for
most compensator work (~ 0.7)
Two-dimensional compensators
 Thickness varies, along a single dimension only.
 Can be constructed using thin sheets of lead,
lucite or aluminum
 3-D compensators are designed to measure
tissue deficits in both transverse and
longitudinal cross sections
 Cavity produced in the Styrofoam block is
used to cast compensator filters
 Various devices are used to drive a
pantographic cutting unit
Three-dimensional compensators
Wedge filters
 Wedge shaped absorber causes a progressive
decrease in intensity across the beam
 Results in tilt of the isodose curve & degree of
the tilt depends upon the slope of the wedge
filter
 Material: tungsten, brass. Lead or steel
Isodose lines in a wedge system
Wedge filters
 The sloping surface is
made either straight or
sigmoid in shade
 A sigmoid shape
produces a straighter
isodose curve
 Mounted on trays
which are mounted on
to the head of the
gantry
Types of wedges
Physical wedges
– Individualized
– Universal
– Motorized wedge
Dynamic wedges
Enhanced Dynamic wedges
Wedge parameters
• The two dimensions of
wedges are important – “X”
or width and “Y” or length.
• All wedges are aligned so that
the central axis of the beam is
at the central axis of the
wedge.
• If the X dimension of field is
longer then we can’t use the
wedge without risking a hot
spot!!
X
This area will have a
hot spot.
Wedge isodose angle (θ) is the complement of the
angle through which the isodose curve is tilted with respect to
the central ray of the beam at any specified depth
This depth is important because the
angle will decrease with increasing
depth.
The choice of the reference depth
varies:
10 centimeters
1/2 - 2/3rd of the beam width
At the 50% isodose curve
Hinge angle,φ
It is the angle between central axes of two
beams passing through the wedge
Relationship b/w φ & θ
Wedge angle,θ= 90 – φ/2
• Degree of separation between wedges
– Distance between the thick ends of wedge filters
as projected on the surface
• Wedge transmission factor
– defined as ratio of dose with and without wedge
at a point in phantom along the central axis of
beam
– Usually measured at a suitable depth below the
Dmax usually 5 -10 cms
– Resultant reduction in output results in an
increase in the treatment time
Physical wedge
• Angled piece of lead or steel that is placed in
the beam to produce a gradient in radiation
intensity
• Manual intervention is required to place
physical wedges on the treatment unit
• Two types
– Individualized
– Universal
Individualized wedge system
• This requires a separate wedge for each beam width
optimally designed to minimize the loss of beam output
• These are used in cobolt teletherapy
• The width (W) of the wedge is fixed
• All systems have the following four angles 15°, 30°, 45°,
60°.
• The wedge systems available are:
– 6W ( x 15)
– 8W ( x 15)
– 10W ( x 15)
Universal wedge
• Single wedge serves for all beam widths. It is fixed
centrally in the beam irrespective of field size.
• However not suitable for cobalt beams because of
excessive reduction of beam output with smaller
fields.
• Come in one size of 20 x 30 cms
It is a physical wedge integrated into the head of the
unit and controlled remotely
( 60° wedge)
Motorized wedge
Dynamic Wedge
• It produces the same wedged intensity
gradient by having one jaw close
gradually while the beam is on
Working principle
Wedge Pair Fields
• For treatment using perpendicular beam
arrangement the superficial region of
tumor receives higher dose or hot spot
occurs
• To avoid this wedges are placed with thick
ends adjacent to each other to get uniform
distribution
Wedge Pair Fields
Working principle
Open and Wedged field combinations
• For treatment of some tumors when open field
anteriorly and wedged field laterally is used
• Dose contribution from anterior field decreases
with depth
• Bilateral wedges produce compensation and
attenuation at thicker end
• Boost to the deeper area by thinner end
Beam fattening filter
• Intensity is more at central axis and
decreases as we move away
• Non-uniform dose at any given depth
• FF is used to uniform it
• Usually made up of Al or Brass
Bolus
• A tissue equivalent material
used to reduce the depth of
the maximum dose (Dmax)
• A bolus can be used in place
of a compensator for
kilovoltage radiation to even
out the skin surface contours
• In megavoltage radiation
bolus is primarily used to
bring up the buildup zone
near the skin in treating
superficial lesions.
 Properties of an ideal bolus:
– Same electron density and atomic number
– Pliable to conform to surface
– thickness of the bolus used varies according to the
energy of the radiation
 In megavoltage radiation:
• Co-60 : 2 - 3 mm
• 6 MV : 7- 8 mm
• 10 MV : 12 - 14 mm
• 25 MV: 18 - 20 mm
• Commonly used materials are:
– Cotton soaked with water.
– Paraffin wax
– Other materials that have been used:
– Mix- D (wax, polyethylene, mag oxide)
– Temex rubber (rubber)
– Lincolnshire bolus (sugar and mag carbonate in form of
spheres)
– Spiers Bolus (rice flour and soda bicarb)
• Commercial materials:
– Superflab: Thick and doesn't undergo elastic deformation.
Made of synthetic oil gel
– Superstuff: Add water to powder to get a pliable gelatin
like material
– Bolx Sheets: Gel enclosed in plastic sheet
Breast Cone
• A beam modifying and directing device used for a
tangential fields therapy
– Advantages:
– Directs beam to the central axis of the area of interest,
where a tangential beam is applied to a curved
surface
– Helps position, the patient with an accurate SSD
– Endplate provides compensation, enhances surface
dose and presses down the tissue.
– Effective shielding of lungs
Penumbra trimmers
• Consists of extensible,
heavy metal bars to
attenuate the beam in the
penumbra region.
• Increase the source to
diaphragm distance,
reducing the geometric
penumbra.
• Another method is to use
secondary blocks placed
close to the patient ( 15 –
20 cms).
Beam Spoilers
• Special beam modification
device where shadow trays
made from Lucite are kept
at a certain distance from
the skin
• Based on the principle that
relative surface dose
increases when the surface
to tray distance is reduced
• First used by Doppke to
increase dose to superficial
neck nodes in head and
neck cancers using 10 MV
photon beams
Beam
Modification
Of Electrons
Scattering foil
A device to widen the thin pencil beam (3 mm)
of electrons
• Metallic plates of tin, lead or aluminium are used
• Disadvantages:
– Beam attenuation
– Generation of bremsstrahlung radiation
• Advantages:
– Less prone to mechanical errors
– Less expensive
– Requires less instrumentation
Internal shielding
 A lead shield can be placed where shielding of
structures against backscatter electrons is
required
 A tissue equivalent material is coated over the
lead shield like wax/ dental acrylic/ aluminum
 Example of areas requiring these techniques are
the buccal mucosa and eye lids.
Lead cut-outs
• For a low-energy electrons (<10 MeV), sheets
of lead, less than 6 mm thickness are used
• Lead sheet can be placed directly on the skin
surface
• Shields can also be supported at the end of
the treatment cone if too heavy at the cost of
greater inaccuracies
• Design is easier, because the size is same as
that of the field on the patients skin
Conclusion
 Beam modification increases conformity allowing a
higher dose delivery to the target, while sparing more
of normal tissue simultaneously
 Megavoltage radiotherapy is better suited for most
forms of beam modification due to it’s favourable
scatter profile
 However any beam modification necessitates a close
scrutiny of every phase of the planning and
treatment process
Drugs are not always necessary.
Belief in recovery always is.
Norman Cousins
American political activist
Thank u…

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Beam modification in radiotherapy

  • 2. Outline Modification of beam Need of beam modification Types of beam modification Devices modifying the beam geometry Working of beam modifiers
  • 3. Beam modification • Defined as desirable modification in the spatial distribution of radiation - within the patient - by insertion of any material in the beam path
  • 4. Four types of beam modification • Shielding: – To eliminate radiation dose to some special parts of the zone at which the beam is directed • Compensation: – To allow normal dose distribution data to be applied to the treated zone where different types of tissues are present • Wedge filtration: – Where a special tilt in isodose curves is obtained • Flattening: – Where the spatial distribution of the natural beam is altered by reducing the central exposure rate relative to the peripheral
  • 5. Beam modification devices 4 main types of beam modifying devices Wedge filter Compensator Bolus Shielding blocks
  • 6. other modification devices Beam spoilers Beam flattening filters Breast cone Penumbra trimmers Electron beam modification
  • 7. Hurdles • Radiation reaching any point, is made up of primary and scattered photons. • introduction of the modification devices results in alteration of dose distribution • The phenomena scattering results in an “blurring” of the effect of the beam modification
  • 8.  The higher scatter contribution to the overall dose results in lower dosage adjacent to the shielded area in kilovoltage radiation.  Lesser amount of scattered radiation with megavoltage radiation means that the attenuation produced by shielding is also more.
  • 9. Shielding to protect the critical structures around the treated volume by using various devices • The aims of shielding are: To protect critical organs Avoid unnecessary irradiation to surrounding normal tissue Matching adjacent fields • It should have following characteristics high atomic number high density easily available inexpensive
  • 10. Shielding Shielding Blocks Independent Jaws Multi Leaf Collimators Custom Blocks
  • 11. Lead as a shielding material • Choice of shielding is also dictated by the type of beam being used.
  • 12.  It’s thickness depends on • Attenuation of shielding material – Half-value layer is defined as the thickness of an absorber required to attenuate the intensity of beam to half its original value. • For practical purposes, the shielding material which reduces beam transmission to 5% of its original is considered acceptable • The number of HVL (n) 1/2n = 5% or 0.05 Thus, 2n = 1/0.05 = 20 .OR, n log 2 = log 20. n = 4.32
  • 13. Placing of Shielding  In Kilovoltage radiation shielding is readily achieved by placing sheets of lead on the surface directly It is necessary because of the lower penetrating power of beam  In Megavoltage radiation, – Thicker blocks used. – Placed higher up in shadow trays (15 -20 cm). – Avoids increase in skin dose due to electron scatter. – Also impossible to place the heavy block on the body
  • 14. Customised blocks • Material used for custom locking is known as the Wood's metal (Cerrobend) • Commercial names  Lipowitz's alloy  Cerrobend,  Bendalloy,  Pewtalloy  MCP 158 • Melting point 70°C. • Density 9.4 g /cm3 at 20°C (83% of lead)
  • 15. Composition Of Cerrobend Lead, 26.70% Bismuth, 50.00%Cadmium, 10.00% Tin, 13.30% Bismuth Lead Tin Cadmium
  • 16. • Major advantage over lead is its low melting point which enables it to cast in any shape. • At room temperature it is harder than lead. • 1.21 times thicker blocks necessary to produce the same attenuation. • Most commonly thickness of 7.5 cms used.
  • 17. Construction of blocks Outline of the treatment field being traced on radiograph using a Styrofoam cutting device. Electrically heated wire pivoting around a point (simulating the source) cutting the styrofoam block Cavities in the styrofoam block being used to cast the Cerrobend blocks.
  • 18. Custom blocks  Shielding blocks can be of two types: • Positive blocks, where central area is blocked • Negative blocks where peripheral area is blocked  Diverging Block – Ideally blocks should be shaped or tapered so that their sides follow the geometric divergence which minimizes the block transmission penumbra
  • 19. Independent Jaws  Used when we want to block of the part of the field without changing the position of the isocenter  Independently movable jaws, allows us to shield a part of the field & can be used for “beam splitting”  Beam is blocked off at the central axis to remove the divergence  Use of independent jaws results in the shift of the isodose curves & penumbra  This is due to the elimination of photon and electrons scatter from the blocked part
  • 20. Multileaf collimators • Multileaf collimators are a bank of large number of collimating blocks or leaves • Can be moved automatically independent of each other to generate a field of any shape. • MLCs are available from all the major medical LINAC manufacturers : Elekta, Siemens & Varian • Independent manufacturers:BrainLab, Radionics, Direx, NOMOS,Novalis
  • 21. MLC Conventional Secondary Tertiary Singly Focused Doubly Focused OR Mini Micro Single Plane Double Plane OR Miniature
  • 22. Intraleaf transmission: radiation transmitted through the full height of the leaf Interleaf transmission: transmitted radiation measured along a line passing between leaf sides Leaf end transmission: transmitted radiation measured along a ray passing between the ends of opposed leaves in their most closed position Leaf Terminology
  • 23.  Secondary MLC: replaces one of the secondary jaws (upper or lower) - Elekta & Siemens  Tertiary MLC: add-on device in the head of linac below the jaw collimators - Varian  Leaves – Elekta (80, microSRS ) – Siemens (58 and 80 leaves) – Varian (52, 80 and 120 leaves)
  • 24. ELEKTA MLC: Y-Jaw replacement No. of leaves 80 Material Tungsten Thickness (height) 7.5 cm Arrangement Tongue and Groove Width at isocentre 1.0 cm Movement path Linear End design Curved/rounded Focusing Single Interdigitization of opposite leaves Possible Position Sensor Optical/CCD camera Back-up jaw thickness 3.0 cm Field size at isocentre 40 x 40 cm2
  • 25. SIEMENS MLC:X-Jaw Replacement No. of leaves 58 Field size at isocentre 40 x 40 cm2 Material Tungsten Thickness (height) 7.6 cm Arrangement Tongue and Groove Width at isocentre 1.0 cm – inner 27 pairs 6.5 cm – outer 2 pairs Movement path Circular arc End design Straight Focusing Double Interdigitization Not Possible Position Sensor Linear encoders
  • 26. VARIAN MLC: Tertiary Material Tungsten Thickness (height) 5.0 cm Arrangement Tongue and Groove Movement path Linear End design Curved/rounded Focusing Single Interdigitization Possible Position Sensor Linear encoders
  • 27. Comparison of leaf assembly (End-on view) Elekta Varian Siemens
  • 28.  Merits • beam shaping is simple and less time consuming • these can be used without needing to enter treatment room • correction and changing of field shape is simple • overall treatment time is shortened • constant control and continuous adjustment of the field shape during irradiation is possible  Demerits • step edge effect • radiation leakage between the leaves • wider penumbra
  • 29. Tissue compensators • Beam modifying device which evens out the skin surface contours, while retaining the skin-sparing advantage • It allows normal depth dose data to be used for such irregular surfaces. • Compensators can also be used for To compensate for tissue heterogeneity. To compensate for dose irregularities arising due to reduced scatter near the field edges.
  • 30. • The dimension and shape of a compensator must be adjusted to account for : – Beam divergence. – Linear attenuation coefficients of the filter material and soft tissue – Reduction in scatter at various depths due to the compensating filters, when it is placed at the distance away from the skin • To compensate for these factors a tissue compensator is always has an attenuation less than that required for primary radiation
  • 31. Thickness ratio or density ratio Required thickness of a tissue equivalent compensator Missing tissue thickness along same ray
  • 32. • The thickness ratio depends on: – Compensator to surface distance,d – Thickness of the missing tissue – Field size – Depth – Beam quality • Distance is the most important factor when d is ≤ 20 cm • A fixed value of thickness ratio (τ) is used for most compensator work (~ 0.7)
  • 33. Two-dimensional compensators  Thickness varies, along a single dimension only.  Can be constructed using thin sheets of lead, lucite or aluminum
  • 34.
  • 35.  3-D compensators are designed to measure tissue deficits in both transverse and longitudinal cross sections  Cavity produced in the Styrofoam block is used to cast compensator filters  Various devices are used to drive a pantographic cutting unit Three-dimensional compensators
  • 36. Wedge filters  Wedge shaped absorber causes a progressive decrease in intensity across the beam  Results in tilt of the isodose curve & degree of the tilt depends upon the slope of the wedge filter  Material: tungsten, brass. Lead or steel
  • 37. Isodose lines in a wedge system
  • 38. Wedge filters  The sloping surface is made either straight or sigmoid in shade  A sigmoid shape produces a straighter isodose curve  Mounted on trays which are mounted on to the head of the gantry
  • 39. Types of wedges Physical wedges – Individualized – Universal – Motorized wedge Dynamic wedges Enhanced Dynamic wedges
  • 40. Wedge parameters • The two dimensions of wedges are important – “X” or width and “Y” or length. • All wedges are aligned so that the central axis of the beam is at the central axis of the wedge. • If the X dimension of field is longer then we can’t use the wedge without risking a hot spot!! X This area will have a hot spot.
  • 41. Wedge isodose angle (θ) is the complement of the angle through which the isodose curve is tilted with respect to the central ray of the beam at any specified depth This depth is important because the angle will decrease with increasing depth. The choice of the reference depth varies: 10 centimeters 1/2 - 2/3rd of the beam width At the 50% isodose curve
  • 42. Hinge angle,φ It is the angle between central axes of two beams passing through the wedge Relationship b/w φ & θ Wedge angle,θ= 90 – φ/2
  • 43. • Degree of separation between wedges – Distance between the thick ends of wedge filters as projected on the surface • Wedge transmission factor – defined as ratio of dose with and without wedge at a point in phantom along the central axis of beam – Usually measured at a suitable depth below the Dmax usually 5 -10 cms – Resultant reduction in output results in an increase in the treatment time
  • 44. Physical wedge • Angled piece of lead or steel that is placed in the beam to produce a gradient in radiation intensity • Manual intervention is required to place physical wedges on the treatment unit • Two types – Individualized – Universal
  • 45. Individualized wedge system • This requires a separate wedge for each beam width optimally designed to minimize the loss of beam output • These are used in cobolt teletherapy • The width (W) of the wedge is fixed • All systems have the following four angles 15°, 30°, 45°, 60°. • The wedge systems available are: – 6W ( x 15) – 8W ( x 15) – 10W ( x 15)
  • 46. Universal wedge • Single wedge serves for all beam widths. It is fixed centrally in the beam irrespective of field size. • However not suitable for cobalt beams because of excessive reduction of beam output with smaller fields. • Come in one size of 20 x 30 cms
  • 47. It is a physical wedge integrated into the head of the unit and controlled remotely ( 60° wedge) Motorized wedge
  • 48. Dynamic Wedge • It produces the same wedged intensity gradient by having one jaw close gradually while the beam is on
  • 49. Working principle Wedge Pair Fields • For treatment using perpendicular beam arrangement the superficial region of tumor receives higher dose or hot spot occurs • To avoid this wedges are placed with thick ends adjacent to each other to get uniform distribution
  • 51. Working principle Open and Wedged field combinations • For treatment of some tumors when open field anteriorly and wedged field laterally is used • Dose contribution from anterior field decreases with depth • Bilateral wedges produce compensation and attenuation at thicker end • Boost to the deeper area by thinner end
  • 52.
  • 53. Beam fattening filter • Intensity is more at central axis and decreases as we move away • Non-uniform dose at any given depth • FF is used to uniform it • Usually made up of Al or Brass
  • 54. Bolus • A tissue equivalent material used to reduce the depth of the maximum dose (Dmax) • A bolus can be used in place of a compensator for kilovoltage radiation to even out the skin surface contours • In megavoltage radiation bolus is primarily used to bring up the buildup zone near the skin in treating superficial lesions.
  • 55.  Properties of an ideal bolus: – Same electron density and atomic number – Pliable to conform to surface – thickness of the bolus used varies according to the energy of the radiation  In megavoltage radiation: • Co-60 : 2 - 3 mm • 6 MV : 7- 8 mm • 10 MV : 12 - 14 mm • 25 MV: 18 - 20 mm
  • 56. • Commonly used materials are: – Cotton soaked with water. – Paraffin wax – Other materials that have been used: – Mix- D (wax, polyethylene, mag oxide) – Temex rubber (rubber) – Lincolnshire bolus (sugar and mag carbonate in form of spheres) – Spiers Bolus (rice flour and soda bicarb) • Commercial materials: – Superflab: Thick and doesn't undergo elastic deformation. Made of synthetic oil gel – Superstuff: Add water to powder to get a pliable gelatin like material – Bolx Sheets: Gel enclosed in plastic sheet
  • 57. Breast Cone • A beam modifying and directing device used for a tangential fields therapy – Advantages: – Directs beam to the central axis of the area of interest, where a tangential beam is applied to a curved surface – Helps position, the patient with an accurate SSD – Endplate provides compensation, enhances surface dose and presses down the tissue. – Effective shielding of lungs
  • 58. Penumbra trimmers • Consists of extensible, heavy metal bars to attenuate the beam in the penumbra region. • Increase the source to diaphragm distance, reducing the geometric penumbra. • Another method is to use secondary blocks placed close to the patient ( 15 – 20 cms).
  • 59.
  • 60.
  • 61.
  • 62. Beam Spoilers • Special beam modification device where shadow trays made from Lucite are kept at a certain distance from the skin • Based on the principle that relative surface dose increases when the surface to tray distance is reduced • First used by Doppke to increase dose to superficial neck nodes in head and neck cancers using 10 MV photon beams
  • 64. Scattering foil A device to widen the thin pencil beam (3 mm) of electrons • Metallic plates of tin, lead or aluminium are used • Disadvantages: – Beam attenuation – Generation of bremsstrahlung radiation • Advantages: – Less prone to mechanical errors – Less expensive – Requires less instrumentation
  • 65. Internal shielding  A lead shield can be placed where shielding of structures against backscatter electrons is required  A tissue equivalent material is coated over the lead shield like wax/ dental acrylic/ aluminum  Example of areas requiring these techniques are the buccal mucosa and eye lids.
  • 66. Lead cut-outs • For a low-energy electrons (<10 MeV), sheets of lead, less than 6 mm thickness are used • Lead sheet can be placed directly on the skin surface • Shields can also be supported at the end of the treatment cone if too heavy at the cost of greater inaccuracies • Design is easier, because the size is same as that of the field on the patients skin
  • 67. Conclusion  Beam modification increases conformity allowing a higher dose delivery to the target, while sparing more of normal tissue simultaneously  Megavoltage radiotherapy is better suited for most forms of beam modification due to it’s favourable scatter profile  However any beam modification necessitates a close scrutiny of every phase of the planning and treatment process
  • 68. Drugs are not always necessary. Belief in recovery always is. Norman Cousins American political activist