Ayurvedic Pharmacology of Celastrus panniculatus & its Pharmacognocy
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This document describes the plant Celastrus panniculatus Willd. It is a large climber or shrub with obovate leaves and pale yellow-white flowers. Its seeds and roots contain various chemical constituents. In Ayurveda, it is known as Jyotishmati and is used to improve cognitive abilities, induce sleep, and treat various Vata disorders. It has properties like Tikshna, Katu, and Ushna which allow it to pacify Vata and Kapha doshas. It has wide applications like treating paralysis, arthritis, skin disorders, and as a diuretic and memory enhancer. Its oil is used topically and internally in small doses
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![Celastrus panniculatus Willd.
CC:- Sirobirechan (c.), arkadi,
adhobhaghara,sirobirechan (su), arkadi (v.)
LN:- Celastrus panniculatus Willd.
FN:- Celastraceae– -Hof]ltidtL s'n_
SN:- jyotishmati, parawatpadi, kaakaandaki,
kangunika, pittaila, katvika, vega.
NN: EN:- Staff tree.](https://image.slidesharecdn.com/jyotismati-140307134254-phpapp02/85/Ayurvedic-Pharmacology-of-Celastrus-panniculatus-its-Pharmacognocy-1-320.jpg)
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This document provides information about marijuana including its appearance, common names, methods of use, classification, addictiveness, short and long term effects, distribution, impact on the brain, and legality. It notes that marijuana is a dry shredded plant that is commonly called weed, pot, or ganja and is usually smoked in joints, bongs or pipes. It is considered a hallucinogen as it impairs perception but its addictiveness is debated, and its long term health effects are not fully known but may include cancer, lung problems and immune system impacts.
Forensic inestigations
The document discusses various types of forensic analyses conducted by the Ghana Centre for Law and Forensic Analysis (GCLA) including drug analysis, questioned documents examination, fingerprint comparison, tool mark examination, gunshot residue analysis, and more. The analyses are used to establish links between suspects, scenes of crime, and evidence. Reports are used by law enforcement, legal professionals, insurance companies, and others. The overall purpose is to detect, reduce, and prevent crimes through forensic science.
Cannabis for Harm Reduction
Harm reduction is an approach to addiction treatment that offers an alternative to abstinence-based programs. Harm reduction operates on the idea that lives can be improved and perhaps saved by substituting a less-harmful substance for one that is more dangerous to the substance user and those around them.
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Hashish presentation
Hashish, or hash, is a resin collected from cannabis plants that is usually smoked. It originated in Morocco in the 1960s and contains THC, which causes hallucinations, paranoia, and addiction in long-term users. While hashish is available and used by many teens due to peer pressure and misperceptions of its effects, its long-term use can lead to health issues like bronchitis and emphysema as well as social problems. The document provides statistics on marijuana use among youth and recommends solutions like parental involvement and drug education to address this issue.
Hemp Cultivation
This document discusses hemp cultivation and its advantages over other crops and materials. It begins by explaining the differences between industrial hemp and marijuana, then outlines various uses of hemp including for fuel, food, paper, plastics, textiles and more. It notes hemp's high yield and that it requires little pesticides. The document also discusses hemp regulation and opposition in different countries and regions. It examines case studies of hemp cultivation and argues that while the potential for hemp exists, challenges around regulation and competition have prevented a thriving global hemp market.
Hemp presentation
This document discusses plans for an upcoming event on hemp at UB presented by the Environmental Network club. It includes an agenda with topics on hemp, its uses, why it should be legalized, and why it isn't currently legal. It also discusses design issues for promotional materials and seeks new ideas for activities during Hemp Week at UB, including tabling, petitions, education, and bracelet making. The goal is to advocate for the legalization of hemp through participation and raising awareness of its benefits.
Introduction to Hemp
This document discusses the benefits of industrial hemp and medical cannabis. It begins by explaining that industrial hemp has very low psychoactive levels but provides many environmental and economic benefits, such as producing fiber, paper and biodegradable plastics. It then summarizes several medical studies that show cannabis may help treat conditions like epilepsy, cancer, Crohn's disease, Parkinson's disease and diabetes. The document emphasizes that hemp and cannabis have many potential benefits and could help address issues like environmental degradation, world hunger and disease.
Hemp
This document discusses the plant Cannabis sativa, commonly known as hemp. It can be harvested and used for various purposes such as fiber, oil, food, medicine, and industrial applications like paper, textiles, and biofuel. Hemp seeds are high in nutrients like magnesium, calcium, iron, and potassium. They contain little to no THC and provide benefits such as increased energy, improved immune system, lowered cholesterol, and rapid recovery from illness or injury when consumed. Hemp seeds can be used to make products like hemp seed oil, hemp milk, hemp flour, and hemp protein powder.
10 conditions cannabis can help
The document discusses 10 medical conditions that may be helped by cannabis: epilepsy, chronic pain, fibromyalgia, post-traumatic stress disorder, multiple sclerosis, migraines, Crohn's disease, glaucoma/iritis, cancer, and Parkinson's disease. For each condition, it provides brief examples or studies that indicate cannabis may effectively treat symptoms, reduce pain, lower seizure activity, combat nausea, and more. The conclusion urges readers to share the information and advocate for legalizing medical cannabis.
Understanding Cannabinoids - How Cannabis Helps Our Bodies
In this Understanding Cannabinoids Slide Share we discuss the Endocannabinoid System, the major cannabinoids in cannabis & their benefits, the Entourage (or Ensemble) Effect and how it all works together.
Cannabis poisoning
Cannabis, also known as marijuana, can lead to abuse and addiction. Cannabis intoxication occurs after ingestion and causes impaired judgment and cognitive issues. Abuse results in problems functioning and legal issues. Dependence is a pattern of use despite harm and inability to limit use. Regular cannabis use increases risks of mental health issues like psychosis and physical health risks like cancer. Treatment focuses on detoxification and managing withdrawal symptoms. Medical use of cannabis may help conditions like nausea, pain, and seizures.
On Cannabis
A 30 minute Powerpoint highlighting part of the history of Cannabis, it's various uses, it's history of being illegal, why it should be legal, it's addiction, potency, and toxicity levels, and why it could help us should it be legal and widely available.
Canabbis
Cannabis, also known as marijuana, is the most widely used illicit drug in the world with approximately 4% of the world's adults using it annually. It comes from the Cannabis sativa plant and contains the active chemical THC. Common forms of cannabis include herbal cannabis, marijuana, bhang, ganja, charas, and hashish oil. Cannabis acts on receptors in the brain to produce effects like relaxation and impaired coordination. Long term effects can include impaired cognitive skills and increased risk of respiratory and cardiovascular issues. Short term effects include anxiety, paranoia, and hallucinations. Cannabis is identified through microscopic examination and color tests.
Drug Abuse PPT by nirav
Drug addiction involves complex interactions between brain circuitry, genetics, environment, and an individual's experiences. The mesolimbic dopamine system plays a key role in addiction, with drugs of abuse activating dopamine release and reinforcement. Animal models show addictive behaviors like prolonged self-administration despite negative consequences. Tolerance and withdrawal are also features of physical dependence. Treatment involves managing withdrawal symptoms, as well as behavioral therapies and medications to address psychological dependence and prevent relapse.
Illegal drugs
This document discusses different types of drugs and their effects. It begins by defining illegal drugs as drugs regulated by law that may be prescribed but are otherwise illegal to sell or use. It then discusses why illegal drug use is dangerous, noting risks of permanent brain and body damage, addiction, suicide, accidents, crime and disease transmission. Reasons people begin using drugs are also summarized as including experimentation, escaping problems, peer pressure and believing drugs solve issues. The stages of drug use are defined as regular use, tolerance, dependence and addiction. Finally, drugs that commonly lead to other drug use are listed as alcohol, tobacco and marijuana.
Presentation drugs
This document discusses drug abuse and addiction. It defines a drug as any substance used for medical purposes and defines addiction as habitual and uncontrolled dependence on a substance. It classifies types of drugs and their examples and discusses how drug addiction often begins due to factors like curiosity, peer pressure, depression, or a desire for excitement. The document specifically examines tobacco and nicotine, noting tobacco's origins and the stimulant and relaxing effects of nicotine but also its risks like increased heart disease and reduced fetal growth. It also looks at alcohol, explaining reasons for drinking like social pressures or wanting to escape difficulties in life. The overall goal is to raise awareness of the harmful effects of drugs.
Power Point Drug Abuse
The most common drug is marijuana. Marijuana use is increasing while opium and cocaine use are decreasing. The year 2000 saw the highest rates of drug use according to the document.
DRUG ABUSE PREVENTION PRESENTATION
This document discusses the dangers of drug abuse, including addiction, health problems, and death. It notes that drugs can affect each person differently based on their brain chemistry and prior drug exposure. Common signs of drug abuse are listed, such as declining interest in activities, mood swings, and associating with known drug users. The most commonly abused drugs in the Philippines like methamphetamine, marijuana, and inhalants are described along with their short and long term negative health effects.
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Best Ayurvedic medicine for Gas and Indigestion
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Top 10 Best Ayurvedic Kidney Stone Syrups in India
we have mentioned the best 10 ayurvedic Kidney Stone Syrups. You can check all these products and choose the best one for yourself.
Journal Article Review on Rasamanikya
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
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Identification and nursing management of congenital malformations Adhd Medication Shortage Uk - trinexpharmacy.com
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
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Ayurvedic Pharmacology of Celastrus panniculatus & its Pharmacognocy
- 1. Celastrus panniculatus Willd. CC:- Sirobirechan (c.), arkadi, adhobhaghara,sirobirechan (su), arkadi (v.) LN:- Celastrus panniculatus Willd. FN:- Celastraceae– -Hof]ltidtL s'n_ SN:- jyotishmati, parawatpadi, kaakaandaki, kangunika, pittaila, katvika, vega. NN: EN:- Staff tree.
- 2. Botanical description: A large climber or shrub. Leaves simple, alternate, stalked, obovate, 5-12cm long, 3-6cm broad, acuminate, toothed, glabrous. Flower pale yellow white in terminal drooping panicles. Fruit capsules, bright yellow when ripe. Seeds 3-6 in no. covered with orange red aril. Flowering in april-june. Fruiting in oct-jan. Distribution in Nepal:- 150-300mt, east to central
- 6. Major chemical constituents: Root & stem bark contain pristimerin. Seeds contain celapagine, celapanigine, celapanine, celastrol, celastrine,paniculatine, malkanguniol, malkangunin.
- 7. Introduction: Jyotishmati literally means an herb which enlightens the brain or the psychic part of the fellow Jyotienlightment; Mati – brain. Jyotishmati improves the cognitive abilities of a fellow. It calms down the always wandering brain and induces natural sleep. It also works well in gynecological problems and Vata diseases like facial paralysis, sciatica and osteoarthritis.
- 8. Ayurvedic Pharmacology of Jyotishmati (Guna): Guna: Tikshna. Rasa: katu & tikta Vipak: katu. Virya: ushna Pravab: Medhya
- 9. Actions (Karma) Effect on Doshas : - Jyotishmati pacifies the Vata Dosha by Snigdha and Ushna; Kapha by Katu, Tikta and Ushna, therefore Jyotishmati is used in Vata Kapha diseases Systemic: External- massage of oil is vatthara, bednasthapan,uttejak. Internal: NS: medhya, nadibalpradayak, mastisk-samak. DS: dipan, anuloman. CS: hridyautejak , sothhara contd….
- 10. contd…. RS: kaphaghna US: mutral by stimulating kidney. Rep.S: vajikaran, aartwajanan. Skin: kusthghna, swedjanan.
- 11. Uses: * it is used in paralysis, backache, Bell’s palsy, arthritis and sciatica. Cervical lymphadenopthy, tuberculosis, adenitis because of Ushna Virya. *. Snigdha and Ushna Gunas improve peristalsis and are therefore useful in overcoming constipation and abdominal distension (flatulence) *. Ushna Guna stimulates heart, improves cardiac output; therefore useful in bradycardia and edema. Jyotishmati oil isuseful in beriberi and osteoarthritis. *. Jyotishmati oil is used for Nasya by its property of Katu, Ushna, Kapha pacifying and brain cleansing. It is also useful in asthma and bronchitis. *. Jyotishmati improves memory by medhya Guna. Ushna property enhances grasping power. Cow’s ghee and Jyotishmati oil mixture is used as a memory enhancer . contd……
- 12. Contd…. *. Morphine addiction can be counteracted by daily consumption of 60 ml. of leaf juice of Jyotishmati or 10 gm of powder in divided dose. *. By increasing the renal circulation due to Ushna Jyotishmati acts as a diuretic. Therefore it is used in dysuria. *. Diaphoretic and cures skin disorders. It is used as antipruritic. *. By Katu and Tikta property which is amapachak and diaphoretic, it is used as antipyretic. Within 2-3hrs. It reduces fever by inducing sweating. Best Recommended Uses :- 5 - 8 drops of Jyotishmati oil should be taken with milk to improve the quality ofsleep. It will calm down the restless mind and deepen the sleep.
- 13. Some classical uses: Udar-rog: jyotishmati oil with sarjikshar.(su.ci.-14) Anartwa: paste of jyotishmati leaves praccesed with kanji.(C.D) Sidhma: oil processed wiyh apamar g kshar jala for 7 times may be applied locallyu.(a.h.ci-19)
- 14. Parts used: Dosage: Seeds & oil Seeds 1-2gm. Oil 5-15drop Important preparation: Jyotishmati tail
- 15. ***The End***