Atrophic rhinitis, a chronic inflammation of the nasal mucosa leading to atrophy of nasal structures, is characterized by scanty mucus, greenish crusts, and a foul odor. The document discusses primary and secondary types of atrophic rhinitis, detailing various etiologies such as genetic factors, nutritional deficiencies, infections, and autoimmune responses. Treatment options include medical interventions like nasal douching and estrogen therapy, as well as various surgical procedures aimed at restoring nasal function and reducing symptoms.

1. Atrophic Rhinitis
Dr. Krishna Koirala

2.  Defined as chronic inflammation of nose characterized
by progressive atrophy of nasal mucosa, including the
glands, turbinate bones and the nerve elements
supplying the nose
 Characterized by formation of scanty viscid secretion &
greenish crusts which emit a foul odour (ozaena)
 Removal of crusts reveals roomy nasal cavity
 Types
 Primary
 Secondary

3. Primary Atrophic Rhinitis

4. Etiology
 Hereditary
 Developmental
 Endocrine
 Racial
 Nutritional deficiency
 Infection
 Autoimmune
 Autonomic Imbalance
 Surfactant deficiency in nasal secretion

5.  Hereditary
 30% cases autosomal inheritance (67% =
Dominant, 33% = Recessive)
 Developmental
 Congenitally spacious nasal cavity
 Poor pneumatization of maxillary antrum
 Endocrine
 Seen during puberty, menopause, menstruation
(symptoms aggravate due to estrogen deficiency)

6.  Racial
 More in American Negroes & Latin (yellow race)
 Nutritional deficiency
 Iron, Vitamin A, Vitamin D
 Infection
 Klebsiella ozaenae (Perez & Abel bacillus),
Coccobacillus foetides ozaena, Bacillus
mucosus, Diphtheroids, Haemophilus influenzae

7.  Autoimmune
 Viral infection / malnutrition / immune deficiency
 trigger destructive autoimmune process on
nasal mucosa
 Autonomic Imbalance
 Reflex Sympathetic Dystrophy Syndrome (R.S.D.S.)
causes vasodilatation & hyperemic decalcification
of turbinates followed by vasoconstriction
 Surfactant deficiency in nasal secretion
 Ciliary dysfunction + stasis of nasal secretions

8. Secondary Atrophic Rhinitis
• Long-standing purulent sinusitis
• Iatrogenic: Radical turbinectomy, post- RT
• Tuberculosis, Syphilis, Leprosy
• Rhinoscleroma
• Deviated nasal septum (atrophy in wider nasal
cavity)

9. Symptoms
 Nasal obstruction
 Greenish -yellow nasal discharge
 Offensive smell (ozaena) due to anaerobic infection,
experienced by relatives
 Merciful anosmia present in the patient
 Bleeding on crust removal

10. Signs
• Roomy nasal cavity with atrophy of mucosa &
turbinates
• Greenish-yellow nasal discharge with crust
formation (begins from posteriorly)
• Foul smell (fetor)
• Nasal Myiasis may be present

11. Nasal crusting

12. Turbinate atrophy & roomy nasal cavity

13. D/D for ozaena D/D for dry nose
1. Atrophic rhinitis 1. Atrophic rhinitis
2. Purulent sinusitis 2. Rhinitis sicca
3. Nasal foreign body 3. Radiotherapy
4. Rhinitis caseosa 4. Sjogren’s syndrome
5. Malignancy

14. Causes of Anosmia
1. Loss of olfactory neural elements
2. Thick secretion & crusts over olfactory area
3. Degeneration of secretary glands  scanty mucus
for dissolving odoriferous materials
Causes of nasal obstruction
1. Blunting of sensory nerve endings
2. Crust formation
3. Lack of eddy current formation in roomy cavity

15. Pathology
• Accumulation of lymphocytes & plasma cells
• Metaplasia from ciliated columnar to squamous
epithelium
• Ciliary destruction & decrease in number & size of
nasal glands
• Bone resorption
• Type I: Endarteritis & periarteritis of terminal arterioles
Benefit from vasodilator effect of estrogen therapy
• Type II: Dilated capillaries worsened by estrogen

16. Specific Investigations
 Saccharine test
 ed nasal muco- ciliary clearance time
 Serum iron & protein levels: malnutrition
 Culture & sensitivity of nasal discharge
 X-ray P.N.S. : maxillary sinusitis

17. C.T. Scan Nose and P.N.S.
 Mucosal thickening
 Resorption of ethmoid bulla
& uncinate process
 Hypoplasia of maxillary
sinuses
 Roomy nasal cavities
 Erosion & bowing of lateral
nasal wall
 Atrophy of turbinates

18. Chest X-ray: T.B., bronchiectasis, lung abscess
Serology for syphilis: V.D.R.L., T.P.H.A., T.P.I.
Sputum for AFB, Mantoux test: T.B.
Nasal smear study: leprosy
Complement fixation test & biopsy: Rhinoscleroma

19. Medical Treatment

20.  Douching  alkaline nasal douche
 Oestradiol nasal spray (1%)
 Glucose (25%) in glycerin nasal drops
 Streptomycin injection
 Placental extract injection
 Autogenous vaccines
 Rifampicin tablet
 Kemicetine anti-ozaena nasal solution
 Mandl’s nasal paint (Potassium Iodide & estradiol)
 Potassium Iodide orally

21. Alkaline Nasal Douche
Sodium bicarbonate (28.4g)  loosens nasal crusts
Sodium biborate (28.4g)  Antiseptic
Sodium chloride (56.7g)  makes soln isotonic
• Mixed in 280 ml of warm water to make the solution
• 6” long rubber tubing fitted in 20 ml plastic syringe
• Syringe nasal cavity while pt bends forward & keeps
saying K, K, K … to close nasopharyngeal isthmus
• Done twice daily till all crusts disappear

22. Surgical Treatment

23.  Young’s operation: Only 1 nostril closed
completely by raising 2 circumferential flaps
(inner mucosal & outer cutaneous) in nasal
vestibule & suturing them in midline
 Modified Young’s operation done by similar
way but keeping a 3 mm opening on both
sides
 Recanalisation done after 12-18 month with
a tri-radiate (Mercedes Benz) incision

24. Pre-operative

25. Mucosal flaps sutured

26. Cutaneous flap sutured

27. Post-operative healed flaps

28. Tri-radiate incision

29. Modified Young’s operation

30. Advantages of Modified Young
 Progress of disease can be monitored with 2.7 mm
nasal endoscope
 Glucose in glycerine drops can be instilled
 Both nostrils can be operated at one sitting
 Nasal breathing preserved
 No complaints of de-nasal voice
 Better cosmetic result

31.  Lautenslager’s operation: Fracture & medial
displacement of lateral nasal wall
 Wilson’s operation: submucosal injection of Teflon
paste
 Antral mucosal transplantation into nasal cavity
through intranasal antrostomy
 Vestibuloplasty: raising a lateral shelf from nasal
vestibular flap to cover the turbinates

32. Pre-operative

33. Lautenslager’s operation

34. Submucosal Teflon paste

35. Antral mucosal transplant

36. Vestibuloplasty

37.  Sympathectomy
 Stellate ganglion block /cervical chain block
 Sublabial implantation
 Placental bits, bone, cartilage, fat, acrylic resin,
Teflon, Silastic
 Parotid duct implantation into maxillary
sinus : Wittmack’s operation

38. Aim of Surgery
 Decrease trauma of air turbulence
 Young , Modified Young ,Lautenslager's ,Wilson
,Sublabial implants ,Vestibuloplasty
 Increase nasal secretions
 Parotid duct implantation into maxillary sinus
 Increase vascularity of nasal mucosa
 Cervical sympathectomy
 Nasal implantation of maxillary sinus mucosa

39. Action of Placental extract
 Progesterone leads to hyperplasia of nasal mucosa &
glandular secretion
 Estrogen leads to vasodilatation
 Biogenic stimulator of metabolic & regenerative
process
 Intra-placental serum boosts up immunity
 Mechanical narrowing of nasal passage