Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate MBBS students in the field of otorhinolaryngology. A clear and concise explanation of the basic concepts in the subject matter concerned. He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal, for teaching undergraduate and postgraduate MBBS students in the field of otorhinolaryngology. A clear and concise explanation of the basic concepts in the subject matter concerned.
Slides prepared and compiled by highly experienced otolarngologist Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate MBBS students in the field of otorhinolaryngology. A clear and concise explanation of the basic concepts in the subject matter concerned. He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal, for teaching undergraduate and postgraduate MBBS students in the field of otorhinolaryngology. A clear and concise explanation of the basic concepts in the subject matter concerned.
Slides prepared and compiled by highly experienced otolarngologist Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal, for teaching undergraduate and postgraduate MBBS students in the field of otorhinolaryngology. A clear and concise explanation of the basic concepts in the subject matter concerned.
Acute suppurative otitis media and and cortical mastoidectomykrishnakoirala4
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal, for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned. He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students.
Epistaxis is one of the commonly encountered problem in day to day life by the otolaryngologists. Most of the times, it is mild , but sometimes, it is very difficult to manage and there may be mortality, too.
This presentation gives a lucid idea of causes of epistaxis, emergency treatment options and operative treatment of epistaxis, too.
Slides prepared by highly experienced ENT teacher, Dr. Krishna Koirala, for teaching undergraduate and postgraduate MBBS students in the field of otorhinolaryngology. A clear and concise explanation of the basic concepts in the subject matter concerned.
CSOM AA might present with both intracranial and extracranial complications. Extracranial complications might again be divided into Intratemporal and extratemporal extracranial.
This presentation explains you about different complications of CSOM in details.
Rhino-sinusitis: inflammation of lining mucosa of nose & paranasal sinuses
Acute: infection lasting < 4 weeks
Sub acute: infection lasting 4 to 12 weeks
Chronic: infection lasting > 12 weeks
Recurrent acute (RARS): > 4 episodes in a year, each episode lasting for 7-10 days, without persistent symptoms in between
Etiology:
Rhinogenic: commonest (85%), following any form of rhinitis
Dental: root abscess, dental procedures (maxillary sinusitis)
Trauma:
Accidental: R.T.A., swimming, diving, F.B., barotrauma
Iatrogenic: nasal packing, septal surgery
Hematogenous : rare
Symptoms
Nasal discharge : mucoid / purulent / blood-stained
Nasal obstruction with hyposmia / anosmia
Headache and facial pain
Cheek / eyelid congestion and swelling
Hawking, sore throat, dry irritating cough
Earache: associated Eustachian tube dysfunction
Constitutional: fever, malaise, body ache
Rhinosinusitis Task Force Criteria (RI 2004)
Location of facial pain in sinusitis
Maxillary sinusitis
Cheek, upper jaw, forehead that increases on bending forward
Frontal sinusitis
Pain over the forehead that increases during morning and decreases by late afternoon (office headache)
Anterior Ethmoid : nasal bridge and peri-orbital, more on eye movement
Posterior Ethmoid : deep seated retro-orbital
Sphenoid : vertex, occipital, retro-orbital pain
Palpation to elicit paranasal sinus tenderness
Maxillary: over the canine fossa
Anterior ethmoid: medial to medial canthus
Frontal: Floor of sinus at the superomedial aspect of the orbit or tap over its anterior wall on the forehead
Postural tests for rhinosinusitis
Performed in acute sinusitis (active nasal discharge)
Pus cleaned in supine position & patient sits upright
Pus appears : frontal or ethmoid sinusitis
Pus appears on stooping forwards: sphenoid sinusitis
No discharge patient lies in lateral position with affected side up
Pus appears: maxillary sinusitis
Plain x ray of Paranasal Sinuses
Water’s view (Occipito -mental) maxillary sinus
Caldwell’s view (Occipito -frontal) and lateral view frontal
Rhese’s view (lateral oblique) and laterai view ethmoids
Base skull view (Submento - vertical) and Pierre’s view (Occipito -mental with mouth open) sphenoid
Air-fluid level seen in acute sinusitis
Mucosal thickening seen in chronic sinusitis
CT scan of nose and PNS
Most reliable imaging modality for sinusitis at present
Plain axial, coronal and sagittal cuts of 3 mm (contrast for suspected vascular, neoplastic, inflammatory lesions)
Helps to delineate the extent of disease, define anatomical variants and study the relationship of sinuses with surrounding structures
Indications:
Recurrent acute/chronic sinusitis not responding to medical treatment
Before endoscopic sinus surgery
Impending complications of sinusitis
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal, for teaching undergraduate and postgraduate MBBS students in the field of otorhinolaryngology. A clear and concise explanation of the basic concepts in the subject matter concerned.
Acute suppurative otitis media and and cortical mastoidectomykrishnakoirala4
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal, for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned. He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students.
Epistaxis is one of the commonly encountered problem in day to day life by the otolaryngologists. Most of the times, it is mild , but sometimes, it is very difficult to manage and there may be mortality, too.
This presentation gives a lucid idea of causes of epistaxis, emergency treatment options and operative treatment of epistaxis, too.
Slides prepared by highly experienced ENT teacher, Dr. Krishna Koirala, for teaching undergraduate and postgraduate MBBS students in the field of otorhinolaryngology. A clear and concise explanation of the basic concepts in the subject matter concerned.
CSOM AA might present with both intracranial and extracranial complications. Extracranial complications might again be divided into Intratemporal and extratemporal extracranial.
This presentation explains you about different complications of CSOM in details.
Rhino-sinusitis: inflammation of lining mucosa of nose & paranasal sinuses
Acute: infection lasting < 4 weeks
Sub acute: infection lasting 4 to 12 weeks
Chronic: infection lasting > 12 weeks
Recurrent acute (RARS): > 4 episodes in a year, each episode lasting for 7-10 days, without persistent symptoms in between
Etiology:
Rhinogenic: commonest (85%), following any form of rhinitis
Dental: root abscess, dental procedures (maxillary sinusitis)
Trauma:
Accidental: R.T.A., swimming, diving, F.B., barotrauma
Iatrogenic: nasal packing, septal surgery
Hematogenous : rare
Symptoms
Nasal discharge : mucoid / purulent / blood-stained
Nasal obstruction with hyposmia / anosmia
Headache and facial pain
Cheek / eyelid congestion and swelling
Hawking, sore throat, dry irritating cough
Earache: associated Eustachian tube dysfunction
Constitutional: fever, malaise, body ache
Rhinosinusitis Task Force Criteria (RI 2004)
Location of facial pain in sinusitis
Maxillary sinusitis
Cheek, upper jaw, forehead that increases on bending forward
Frontal sinusitis
Pain over the forehead that increases during morning and decreases by late afternoon (office headache)
Anterior Ethmoid : nasal bridge and peri-orbital, more on eye movement
Posterior Ethmoid : deep seated retro-orbital
Sphenoid : vertex, occipital, retro-orbital pain
Palpation to elicit paranasal sinus tenderness
Maxillary: over the canine fossa
Anterior ethmoid: medial to medial canthus
Frontal: Floor of sinus at the superomedial aspect of the orbit or tap over its anterior wall on the forehead
Postural tests for rhinosinusitis
Performed in acute sinusitis (active nasal discharge)
Pus cleaned in supine position & patient sits upright
Pus appears : frontal or ethmoid sinusitis
Pus appears on stooping forwards: sphenoid sinusitis
No discharge patient lies in lateral position with affected side up
Pus appears: maxillary sinusitis
Plain x ray of Paranasal Sinuses
Water’s view (Occipito -mental) maxillary sinus
Caldwell’s view (Occipito -frontal) and lateral view frontal
Rhese’s view (lateral oblique) and laterai view ethmoids
Base skull view (Submento - vertical) and Pierre’s view (Occipito -mental with mouth open) sphenoid
Air-fluid level seen in acute sinusitis
Mucosal thickening seen in chronic sinusitis
CT scan of nose and PNS
Most reliable imaging modality for sinusitis at present
Plain axial, coronal and sagittal cuts of 3 mm (contrast for suspected vascular, neoplastic, inflammatory lesions)
Helps to delineate the extent of disease, define anatomical variants and study the relationship of sinuses with surrounding structures
Indications:
Recurrent acute/chronic sinusitis not responding to medical treatment
Before endoscopic sinus surgery
Impending complications of sinusitis
Nasal Polyps are defined as pale, polypoidal, pedunculated , prolapsed sinus mucosa into the nose.
They cause nasal obstruction. Nasal allergy and infecions are proposed to be the most common etiological factors for nasal polyps.
This presentation explains in detail about every aspect of nasal polyps.
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal, for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal, for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal, for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal, for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students.
This presentation gives a lucid idea about different neoplasms of nose like inverted papilloma, ca maxilla, ethmoid and so on.
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Deviated nasal septum and other septal conditionskrishnakoirala4
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides were prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared and compiled by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate ENT students in the field of otorhinolaryngology.
A clear and concise explanation of the basic concepts in the subject matter concerned.
He is the Head of department with a sound knowledge in the field of ENT to teach both undergraduate and postgraduate ENT students
Slides prepared by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate MBBS students in the field of otorhinolaryngology. A clear and concise explanation of the basic concepts in the subject matter concerned.
Deviated nasal septum and other septal conditionskrishnakoirala4
Slides prepared by highly experienced ENT teacher, Dr. Krishna Koirala from Nepal , for teaching undergraduate and postgraduate MBBS students in the field of otorhinolaryngology. A clear and concise explanation of the basic concepts in the subject matter concerned.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
2. • Rhino-sinusitis: inflammation of lining mucosa of nose & paranasal sinuses
• Acute: infection lasting < 4 weeks
• Sub acute: infection lasting 4 to 12 weeks
• Chronic: infection lasting > 12 weeks
• Recurrent acute (RARS): > 3 episodes of rhinosinusitis in 6 months or > 4
episodes in a year, each episode lasting for 7-10 days, without persistent
symptoms in between
Definitions
3. Types of sinusitis
• Acute / sub acute / chronic / recurrent
• Open / Closed (depending on its drainage)
• Unilateral / bilateral
• Maxillary / frontal / ethmoidal / sphenoidal
• Single / multi / pan-sinusitis
• Anterior / posterior group
• Suppurative / hypertrophic
• Bacterial / fungal / allergic / occupational
4. Etiology
• Rhinogenic: commonest (85%), following any form of rhinitis
• Dental: maxillary sinusitis, root abscess, dental procedures
• Trauma:
– R.T.A., swimming, diving, F.B., barotrauma
– Iatrogenic: nasal packing, septal surgery
• Hematogenous : rare
10. Progress
• Severity and resolution depends on
– Open / closed
– Virulence of the organism
– Host resistance
– Treatment received
11. • Ostio-meatal complex is key
area for causation of infection
in anterior group of sinuses
• Pathological variants of ostio -
meatal complex play a major
role in causation of sinusitis
due to reduced ventilation and
drainage of sinuses
12. Clinical features of Rhinosinusitis
• Symptoms
− Nasal discharge : mucoid / purulent / blood-stained
− Nasal obstruction with hyposmia / anosmia
− Headache and facial pain
− Cheek / eyelid congestion and swelling
− Hawking, sore throat, dry irritating cough
− Earache: associated Eustachian tube dysfunction
− Constitutional: fever, malaise, body ache
13. Location of facial pain in Rhinosinusitis
• Maxillary sinusitis
− Cheek, upper jaw, forehead that increases on bending forward
• Frontal sinusitis
− Forehead that increases during morning and decreases by late
afternoon (office headache)
• Anterior Ethmoid: nasal bridge and peri-orbital, more on eye movement
• Posterior Ethmoid : deep seated retro-orbital
• Sphenoid : vertex, occipital, retro-orbital pain
14. Signs of Rhinosinusitis
• Congested and edematous nasal mucosa
• Nasal discharge (anterior and posterior rhinoscopy)
−Middle meatus: frontal, maxillary, anterior ethmoid
−Superior meatus: posterior ethmoid, sphenoid
• Tenderness over the paranasal sinuses
• Postnasal drip, granular pharyngitis
• Cheek swelling in maxillary sinusitis
• Lid edema in ethmoid & frontal sinusitis
15. Palpation to elicit paranasal sinus tenderness
• Maxillary: over the canine fossa
• Anterior ethmoid: medial to medial canthus
• Frontal: Floor of sinus at the superomedial
aspect of the orbit or tap over its anterior
wall on the forehead
16.
17. Transillumination test for sinuses
• Performed in a dark room.
• High-intensity light source placed inside patient’s mouth or
against the cheek (for maxillary sinus) & under medial
aspect of supra-orbital ridge (for frontal sinus)
• Trans-illumination normal : no sinusitis
• Trans-illumination absent : sinus filled with pus
• Trans-illumination dull : equivocal result
18. Postural tests for sinusitis
• Performed in acute sinusitis (active nasal discharge)
• Pus cleaned in supine position & pt sits upright
• Pus appears = frontal or ethmoid sinusitis
• Pus appears on stooping forwards = sphenoid sinusitis
• No discharge pt lies in lateral position with affected side up
• Pus appears = maxillary sinusitis
19. Rhinosinusitis Task Force Criteria
Major Minor
1. Facial pain / pressure 1. Headache
2. Nasal obstruction 2. Fever (non-acute sinusitis)
3. Nasal discharge or 3. Halitosis
discolored postnasal drip 4. Fatigue
4. Hyposmia / anosmia 5. Dental pain
5. Purulence on exam 6. Cough
6. Fever (acute sinusitis) 7. Ear pain / pressure / fullness
Presence of 2 major factors or 1 major + 2 minor factors = sinusitis
20. Investigations
1. Diagnostic nasal endoscopy (D.N.E.)
2. Maxillary Sinoscopy
3. X-ray of P.N.S.
4. U.S.G. of maxillary sinus (Rhinoscan)
5. C.T. scan of P.N.S.
6. M.R.I. of P.N.S.: rarely done
7. Allergic tests
8. Proof puncture (antral wash): for maxillary sinus
9. Endoscopic microswab for culture & sensitivity
10. Fungal culture: of cheesy nasal discharge
22. • Patients not responding to medical therapy
• Anatomic factor preventing adequate
examination by anterior rhinoscopy
• Collection of pus from hiatus semilunaris
for culture & sensitivity
• Objective monitoring of patients
• Peri-operative nasal inspection & cleaning
Indications for D.N.E.
Pus seen in middle meatus
on doing D.N.E.
23. Maxillary sinoscopy
• Anterior sinus wall perforated directly through
canine fossa between roots of 3rd & 4th teeth
with maxillary sinus trocar & cannula
• Trocar removed and sinoscope introduced
through cannula to see inside the maxillary
sinus
24. Plain X- ray of Paranasal sinuses
• Water’s view (Occipito -mental) maxillary sinus
• Caldwell’s view (Occipito -frontal) and lateral view
frontal
• Rhese’s view (lateral oblique) and lateral view
ethmoids
• Base skull view (Submento -vertical) and Pierre’s view
(Occipito -mental with mouth open) sphenoid
− Air-fluid level seen in acute sinusitis
− Mucosal thickening seen in chronic sinusitis
25. Para-nasal sinus sonography
• Bony anterior wall is seen as hyper-echoic line
• Maxillary cavity filled with air appears as hyper-
echoic hence posterior sinus margin not seen
• Fluid in sinus, cyst & mucosal thickening are
hypoechoic, so posterior sinus margin is visible
• B mode sonogram differentiates between fluid
in sinus, cyst & mucosal thickening
26. C.T. scan of Nose and PNS
• Most reliable imaging modality for sinusitis at present
• Plain axial, coronal and sagittal cuts of 3 mm
• Contrast for suspected vascular, neoplastic, inflammatory lesions
• Helps to delineate the extent of disease, define anatomical
variants and study the relationship of sinuses with
surrounding structures
• Indications:
• Recurrent acute/chronic sinusitis not responding to medical treatment
• Before endoscopic sinus surgery
• Impending complications of sinusitis
27. Plain C.T. scan Nose and PNS: Maxillary and ethmoid sinusitis
30. M.R.I. of P.N.S.
• Indications
−To assess the intracranial extension of
sinonasal disease, brain abscess due to
sinusitis and meningocele or encephalocele
−Malignant neoplasms of sinonasal tract
−To evaluate the orbital complications of
sinusitis