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uran 29:45 (O Prophet) convey to people all that is revealed to you of the
Book, and establish system of Salat (establish the Divine System). For, verily,
establishment of Salat (the Divine System) will shut off lewdness, stinginess and
behavior contrary to the Divine Values. This is so, because Allah’s Law is the Greatest
Law that can give you eminence. And (O People) Allah knows whatever you contrive on
your own.
Vasomotor And Atrophic rhinitis
By
Lt Col Saeed Ullah, MBBS, MCPS,
FCPS Classified ENT, Head and
Neck surgeon CMH Quetta
Anatomy of Nose
Anatomy of Nose
Histology
Sensory nerve supply of nose
Sensory nerve supply- septum
Sensory nerve supply-lateral wall
Autonomic nerve supply
Autonomic nerve supply
• Sympatheitic stimulation
▫ Vasoconstriction
▫ Smooth muscle around sinusoids constrict
▫ Decongestion and opening of nose
• Parasympathetic stimulation
▫ Engorgement of nasal mucosa
▫ Increase glandular activity
▫ Nasal congestion and blockage
Definition of rhinitis
• Inflammation of nasal lining, characterized by
one or more of the following symptoms
▫ Nasal congestion
▫ Rhinorrhoea
▫ Sneezing
▫ Itching
Classification of rhinitis
Classification
• Non allergic rhinitis
▫ Idiopathic rhinitis
 Vasomotor rhinitis(non allergic, non infectious
prennial rhinitis(NANIPER)
 Non allergic occupational rhinitis
 Hormonal rhinitis
 Drug induced rhinitis
 Atrophic rhinitis
 NARES(non allergic rhinitis with eosinophilia
syndrome)
Vasomotor rhinitis(NANIPER)
• Non allergic, non infectious perennial rhinitis
• Clinically simulates allergic rhinitis
▫ Paroxysmal sneezing
▫ Watery nasal discharge
▫ Nasal obstruction
Pathogenesis
• Rich blood supply of nasal mucosa
• The turbinate’s erectile tissues
• Sinusoids surrounded by smooth muscle fibers
• Under control of autonomic nerves
• Autonomic nerves under control of
hypothalamus
• Sympathetic stimulation leads to
vasoconstriction
• Parasympathetic stimulation causes
vasodilatation
Pathogenesis
• Unstable autonomic nervous system
▫ Parasympathetic dominance
• Nasal mucosa is hyper reactive
▫ Change in temp
▫ Humidity
▫ Blasts of air
▫ Dust and smoke
Symptoms
• Paroxysmal sneezing
• Excessive rhinorrhea
• Nasal obstruction
• Post nasal drip
Signs
• Congested nasal mucosa
• Hypertrophy of nasal mucosa
• Mucoid nasal discharge
• Nasal polypi
• Hypertrophy of turbinates
Investigations
• Diagnosis of exclusion
▫ Skin prick tests
▫ Serum IgE level
▫ Specific antibodies against IgE
▫ Eosinophils level in nasal smear
Treatment
• Medical
▫ Avoidance of trigger factores
▫ Antihistamins
▫ Nasal decongestants
▫ Topical steroids
• Surgical
▫ Turbinates reduction
▫ Vidian neurectomy
Atrophic rhinitis
Atrophic rhinitis
Chronic inflammatory condition in which nasal
mucosa, glands & bones are atrophied There is
widening of nasal cavities with greenish crusts
in nasal cavities
Types of Atrophic rhinitis
1. Primary:
exact cause is not known
2. Secondary:
to some underlying factors
Primary atrophic rhinitis
• Infection
 Klebsiella Ozaenae
 Diphthroid Bacillus
 Coccobacillus foetidus ozaenae
• Hormonal imbalance
 At puberty
 More common in females
• Nutritional
 Poor socioeconomic status
 Vit D and iron deficiency
• Heredity
• Autoimmune
Organisms (cause,effect)
1. Bacillus ozaenae
2. Coccobacillus
3. Klebsiella ozaenae
4. Diphtheroid bacilli
Secondary Atrophic Rhinitis
1. Chronic purulent sinusitis
2. Enthusiastic surgery on nose
3. Syphilis
4. Tuberculosis
5. Marked DNS with wide nasal cavity on one
side
Pathology
• Epithelium
 Patches of metaplasia
 Transition from ciliated columner into stratified
squamous
• Lamina propria
 Chronic cellular infilterats
 Granulation tissues, fibrosis
• Mucous glands
 Decrease in size and number
• Vascular
 Decreased vascularity
Symptoms
 Nasal obstruction due to:
Crusts
Loss of sense of air passage
 Recurrent Epistaxis
 Offensive smell (stench)
 Anosmia due to Atrophy of Olfactory nerve
 Headache
 Choking
Signs
• External nasal deformity
• Very wide nasal cavities
• Inf. Turbinates shrunken / rudimentary
• Greenish / dirty crusts
• Stench (dead body like smell)
• Maggots
Wide nasal cavities
Crust formation
Greenish nasal discharge- foul smelling
Investigations
1. X-RAY PNS
2. Blood CP, ESR
3. X-RAY chest PA
4. Swab C/S
5. Serology
6. Serum iron & Proteins
7. Biopsy
Treatment
Conservative:
 Alkaline nasal douches with ¼ lit. of warm
lotion of
Sod. Chloride 2 parts
Sod. Bicarbonate 1 part
Sod. Diborate 1 part
 Removal of crusts
 25% Glucose in glycerin nasal drops
 Oestradiol in Arachis oil
Treatment
Surgical Treatment:
 Narrowing nasal cavities:
Injecting Paraffin or Teflon submucosally
Insertion of cartilage graft
 Stellate ganglion block
 Parotid duct transposition
 Closure of one / both nostrils leaving 3mm
hole
Young’s operation
Thank you

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Vasomotor and atrophic rhinitis

  • 1.
  • 2. uran 29:45 (O Prophet) convey to people all that is revealed to you of the Book, and establish system of Salat (establish the Divine System). For, verily, establishment of Salat (the Divine System) will shut off lewdness, stinginess and behavior contrary to the Divine Values. This is so, because Allah’s Law is the Greatest Law that can give you eminence. And (O People) Allah knows whatever you contrive on your own.
  • 3. Vasomotor And Atrophic rhinitis By Lt Col Saeed Ullah, MBBS, MCPS, FCPS Classified ENT, Head and Neck surgeon CMH Quetta
  • 11. Autonomic nerve supply • Sympatheitic stimulation ▫ Vasoconstriction ▫ Smooth muscle around sinusoids constrict ▫ Decongestion and opening of nose • Parasympathetic stimulation ▫ Engorgement of nasal mucosa ▫ Increase glandular activity ▫ Nasal congestion and blockage
  • 12. Definition of rhinitis • Inflammation of nasal lining, characterized by one or more of the following symptoms ▫ Nasal congestion ▫ Rhinorrhoea ▫ Sneezing ▫ Itching
  • 14. Classification • Non allergic rhinitis ▫ Idiopathic rhinitis  Vasomotor rhinitis(non allergic, non infectious prennial rhinitis(NANIPER)  Non allergic occupational rhinitis  Hormonal rhinitis  Drug induced rhinitis  Atrophic rhinitis  NARES(non allergic rhinitis with eosinophilia syndrome)
  • 15. Vasomotor rhinitis(NANIPER) • Non allergic, non infectious perennial rhinitis • Clinically simulates allergic rhinitis ▫ Paroxysmal sneezing ▫ Watery nasal discharge ▫ Nasal obstruction
  • 16. Pathogenesis • Rich blood supply of nasal mucosa • The turbinate’s erectile tissues • Sinusoids surrounded by smooth muscle fibers • Under control of autonomic nerves • Autonomic nerves under control of hypothalamus • Sympathetic stimulation leads to vasoconstriction • Parasympathetic stimulation causes vasodilatation
  • 17. Pathogenesis • Unstable autonomic nervous system ▫ Parasympathetic dominance • Nasal mucosa is hyper reactive ▫ Change in temp ▫ Humidity ▫ Blasts of air ▫ Dust and smoke
  • 18. Symptoms • Paroxysmal sneezing • Excessive rhinorrhea • Nasal obstruction • Post nasal drip
  • 19. Signs • Congested nasal mucosa • Hypertrophy of nasal mucosa • Mucoid nasal discharge • Nasal polypi • Hypertrophy of turbinates
  • 20. Investigations • Diagnosis of exclusion ▫ Skin prick tests ▫ Serum IgE level ▫ Specific antibodies against IgE ▫ Eosinophils level in nasal smear
  • 21. Treatment • Medical ▫ Avoidance of trigger factores ▫ Antihistamins ▫ Nasal decongestants ▫ Topical steroids • Surgical ▫ Turbinates reduction ▫ Vidian neurectomy
  • 23. Atrophic rhinitis Chronic inflammatory condition in which nasal mucosa, glands & bones are atrophied There is widening of nasal cavities with greenish crusts in nasal cavities
  • 24. Types of Atrophic rhinitis 1. Primary: exact cause is not known 2. Secondary: to some underlying factors
  • 25. Primary atrophic rhinitis • Infection  Klebsiella Ozaenae  Diphthroid Bacillus  Coccobacillus foetidus ozaenae • Hormonal imbalance  At puberty  More common in females • Nutritional  Poor socioeconomic status  Vit D and iron deficiency • Heredity • Autoimmune
  • 26. Organisms (cause,effect) 1. Bacillus ozaenae 2. Coccobacillus 3. Klebsiella ozaenae 4. Diphtheroid bacilli
  • 27. Secondary Atrophic Rhinitis 1. Chronic purulent sinusitis 2. Enthusiastic surgery on nose 3. Syphilis 4. Tuberculosis 5. Marked DNS with wide nasal cavity on one side
  • 28. Pathology • Epithelium  Patches of metaplasia  Transition from ciliated columner into stratified squamous • Lamina propria  Chronic cellular infilterats  Granulation tissues, fibrosis • Mucous glands  Decrease in size and number • Vascular  Decreased vascularity
  • 29. Symptoms  Nasal obstruction due to: Crusts Loss of sense of air passage  Recurrent Epistaxis  Offensive smell (stench)  Anosmia due to Atrophy of Olfactory nerve  Headache  Choking
  • 30. Signs • External nasal deformity • Very wide nasal cavities • Inf. Turbinates shrunken / rudimentary • Greenish / dirty crusts • Stench (dead body like smell) • Maggots
  • 33. Greenish nasal discharge- foul smelling
  • 34. Investigations 1. X-RAY PNS 2. Blood CP, ESR 3. X-RAY chest PA 4. Swab C/S 5. Serology 6. Serum iron & Proteins 7. Biopsy
  • 35. Treatment Conservative:  Alkaline nasal douches with ¼ lit. of warm lotion of Sod. Chloride 2 parts Sod. Bicarbonate 1 part Sod. Diborate 1 part  Removal of crusts  25% Glucose in glycerin nasal drops  Oestradiol in Arachis oil
  • 36. Treatment Surgical Treatment:  Narrowing nasal cavities: Injecting Paraffin or Teflon submucosally Insertion of cartilage graft  Stellate ganglion block  Parotid duct transposition  Closure of one / both nostrils leaving 3mm hole Young’s operation

Editor's Notes

  1. Sympatheitic nerve fibers Carotid plexus Deep petrosal nerve Do not form synopsis in pterygopalatine ganglion Secretomotor and vasomotor Parasympathetic nerve fibers Superior salivatory nucleus Greater petrosal nerve Vidian nerve
  2. This slide shows the greenis nasal discharge which forms as a result of the changes occurred in the glands