The document discusses artificial insemination, which involves depositing semen into a woman's vagina, cervical canal, or uterus through instruments to induce pregnancy without intercourse. There are three types of artificial insemination: intravaginal, intracervical, and intrauterine. Sperm can be obtained through masturbation, condoms, intercourse, or direct puncture. The two main types are artificial insemination by husband (AIH) using the husband's sperm, and artificial insemination by donor (AID) using donor sperm. Couples seek AIH for fertility issues and AID for genetic diseases, sterility, or blood incompatibility.
The HFEA is the independent regulator for IVF treatment and human embryo research and came into effect on 1 August 1991. The 1990 Act ensured the regulation, through licensing, of:
the creation of human embryos outside the body and their use in treatment and research
the use of donated gametes and embryos
the storage of gametes and embryos.
Artificial insemination is the deliberate introduction of sperm into a female's cervix or uterine cavity for the purpose of achieving a pregnancy through in vivo fertilization by means other than sexual intercourse or in vitro fertilisation.
The HFEA is the independent regulator for IVF treatment and human embryo research and came into effect on 1 August 1991. The 1990 Act ensured the regulation, through licensing, of:
the creation of human embryos outside the body and their use in treatment and research
the use of donated gametes and embryos
the storage of gametes and embryos.
Artificial insemination is the deliberate introduction of sperm into a female's cervix or uterine cavity for the purpose of achieving a pregnancy through in vivo fertilization by means other than sexual intercourse or in vitro fertilisation.
The Assisted Reproductive Techniques - ART (IVF, IUI, ZIFT, GIFT, ICSI etc.)Muhammad Anas Shamsi
Assisted reproductive technology (ART) is used to treat infertility. It includes fertility treatments that handle both a woman's egg and a man's sperm. It works by removing eggs from a woman's body. The eggs are then mixed with sperm to make embryos. The embryos are then put back in the woman's body. In vitro fertilization (IVF) is the most common and effective type of ART.
ART refers to methods used to achieve pregnancy by artificial or partially artificial means.
• INCLUDES- artificial insemination, In vitro fertilization (IVF) , Zygote intrafallopian transfer (ZIFT) or Tubal Embryo Transfer, Gamete intrafallopian transfer (GIFT) , Intracytoplasmic sperm injection (ICSI)
i. Intrauterine insemination (IUI).
ii. In vitro fertilization and embryo transfer (IVF and ET).
iii. Gamete intra-fallopian transfer (GIFT).
iv. Zygote intra-fallopian transfer (ZIPT).
v. Intra-vaginal culture (IVC).
vi. Cytoplasmic transfer (CT).
Ethical issues associated with fertility treatmentChris Willmott
These slides are from a talk I was invited to give at the Teacher Scientist Network (www.tsn.org.uk) Master Class on Reproductive Technologies.
This turns out to be a series of CPD events for science teachers from East Anglia, hosted on the Norwich Research Park. The aim of the events is specifically to inform teachers about cutting edge developments in biology and biomedicine (rather than, say, discuss suitable classroom activities). It looks like they've got a really good thing going - congratulations to Phil Smith who organises the TSN.
Details of the day can be found at http://tinyurl.com/tsnfertility My slides are presented her unaltered from the version I used on the day. With hindsight, on the basis of discussion after the talk, I might have added in a couple of things. For example, I gather that from an Islamic perspective the soul is not believed to have entered the body at the time when PGD would be conducted and hence this is culturally acceptable (and preferable to, for example, a later termination).
see more resources at bioethicsbytes.wordpress.com
The Assisted Reproductive Techniques - ART (IVF, IUI, ZIFT, GIFT, ICSI etc.)Muhammad Anas Shamsi
Assisted reproductive technology (ART) is used to treat infertility. It includes fertility treatments that handle both a woman's egg and a man's sperm. It works by removing eggs from a woman's body. The eggs are then mixed with sperm to make embryos. The embryos are then put back in the woman's body. In vitro fertilization (IVF) is the most common and effective type of ART.
ART refers to methods used to achieve pregnancy by artificial or partially artificial means.
• INCLUDES- artificial insemination, In vitro fertilization (IVF) , Zygote intrafallopian transfer (ZIFT) or Tubal Embryo Transfer, Gamete intrafallopian transfer (GIFT) , Intracytoplasmic sperm injection (ICSI)
i. Intrauterine insemination (IUI).
ii. In vitro fertilization and embryo transfer (IVF and ET).
iii. Gamete intra-fallopian transfer (GIFT).
iv. Zygote intra-fallopian transfer (ZIPT).
v. Intra-vaginal culture (IVC).
vi. Cytoplasmic transfer (CT).
Ethical issues associated with fertility treatmentChris Willmott
These slides are from a talk I was invited to give at the Teacher Scientist Network (www.tsn.org.uk) Master Class on Reproductive Technologies.
This turns out to be a series of CPD events for science teachers from East Anglia, hosted on the Norwich Research Park. The aim of the events is specifically to inform teachers about cutting edge developments in biology and biomedicine (rather than, say, discuss suitable classroom activities). It looks like they've got a really good thing going - congratulations to Phil Smith who organises the TSN.
Details of the day can be found at http://tinyurl.com/tsnfertility My slides are presented her unaltered from the version I used on the day. With hindsight, on the basis of discussion after the talk, I might have added in a couple of things. For example, I gather that from an Islamic perspective the soul is not believed to have entered the body at the time when PGD would be conducted and hence this is culturally acceptable (and preferable to, for example, a later termination).
see more resources at bioethicsbytes.wordpress.com
Assisted Reproductive Technologies (ART)
First Successful IVF: Birth of Louise Brown in 1978
Rapid developments in the field of ART
Moral panic
Ethics
Ethical issues
Ethical concerns
Moral issues
Social issues
Religion
Case study
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cell
R3 Stem Cells and Kidney Repair: A New Horizon in Nephrology" explores groundbreaking advancements in the use of R3 stem cells for kidney disease treatment. This insightful piece delves into the potential of these cells to regenerate damaged kidney tissue, offering new hope for patients and reshaping the future of nephrology.
CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations.
Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences.
The Promise: CRISPR offers exciting possibilities:
Gene Therapy: Correcting genetic diseases like cystic fibrosis.
Agriculture: Engineering crops resistant to pests and harsh environments.
Research: Studying gene function to unlock new knowledge.
The Peril: Ethical concerns demand attention:
Off-target Effects: Unintended DNA edits can have unforeseen consequences.
Eugenics: Misusing CRISPR for designer babies raises social and ethical questions.
Equity: High costs could limit access to this potentially life-saving technology.
The Path Forward: Responsible development is crucial:
International Collaboration: Clear guidelines are needed for research and human trials.
Public Education: Open discussions ensure informed decisions about CRISPR.
Prioritize Safety and Ethics: Safety and ethical principles must be paramount.
CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)
The Importance of Community Nursing Care.pdfAD Healthcare
NDIS and Community 24/7 Nursing Care is a specific type of support that may be provided under the NDIS for individuals with complex medical needs who require ongoing nursing care in a community setting, such as their home or a supported accommodation facility.
Empowering ACOs: Leveraging Quality Management Tools for MIPS and BeyondHealth Catalyst
Join us as we delve into the crucial realm of quality reporting for MSSP (Medicare Shared Savings Program) Accountable Care Organizations (ACOs).
In this session, we will explore how a robust quality management solution can empower your organization to meet regulatory requirements and improve processes for MIPS reporting and internal quality programs. Learn how our MeasureAble application enables compliance and fosters continuous improvement.
One of the most developed cities of India, the city of Chennai is the capital of Tamilnadu and many people from different parts of India come here to earn their bread and butter. Being a metropolitan, the city is filled with towering building and beaches but the sad part as with almost every Indian city
ICH Guidelines for Pharmacovigilance.pdfNEHA GUPTA
The "ICH Guidelines for Pharmacovigilance" PDF provides a comprehensive overview of the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines related to pharmacovigilance. These guidelines aim to ensure that drugs are safe and effective for patients by monitoring and assessing adverse effects, ensuring proper reporting systems, and improving risk management practices. The document is essential for professionals in the pharmaceutical industry, regulatory authorities, and healthcare providers, offering detailed procedures and standards for pharmacovigilance activities to enhance drug safety and protect public health.
Global launch of the Healthy Ageing and Prevention Index 2nd wave – alongside...ILC- UK
The Healthy Ageing and Prevention Index is an online tool created by ILC that ranks countries on six metrics including, life span, health span, work span, income, environmental performance, and happiness. The Index helps us understand how well countries have adapted to longevity and inform decision makers on what must be done to maximise the economic benefits that comes with living well for longer.
Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
The speakers included:
Professor Orazio Schillaci, Minister of Health, Italy
Dr Hans Groth, Chairman of the Board, World Demographic & Ageing Forum
Professor Ilona Kickbusch, Founder and Chair, Global Health Centre, Geneva Graduate Institute and co-chair, World Health Summit Council
Dr Natasha Azzopardi Muscat, Director, Country Health Policies and Systems Division, World Health Organisation EURO
Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
Dr Shyam Bishen, Head, Centre for Health and Healthcare and Member of the Executive Committee, World Economic Forum
Dr Karin Tegmark Wisell, Director General, Public Health Agency of Sweden
The dimensions of healthcare quality refer to various attributes or aspects that define the standard of healthcare services. These dimensions are used to evaluate, measure, and improve the quality of care provided to patients. A comprehensive understanding of these dimensions ensures that healthcare systems can address various aspects of patient care effectively and holistically. Dimensions of Healthcare Quality and Performance of care include the following; Appropriateness, Availability, Competence, Continuity, Effectiveness, Efficiency, Efficacy, Prevention, Respect and Care, Safety as well as Timeliness.
Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
According to WHO,
Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance.
According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
2. Page 2
First Page
Consists of depositing a
man’s semen in the
vagina, cervical canal or
uterus, through the use of
instruments (e.g. syringe)
to bring about conception
unattained or unattainable
by sexual intercourse.
3. Page 3
The process can either be:
1. intravaginal
• Placing the semen in the vaginal vault
2. Intracervical
• In the cervical cavity
3. Intrauterine
• Inside the uterus itself
4. Page 4
Extraction of semen:
1. Masturbation
• After a short period of abstinence from
ejaculation 3 to 12 days
2. Condomistic intercourse
3. Coitus interruptus
4. Anal massage of the prostate gland
5. Direct puncture of the epididymis
(excretory duct of the testicle)
5. Page 5
TYPES OF ARTIFICIAL
INSEMINATION
1. ARTIFICIAL INSEMINATION BY
HUSBAND (AIH)
• CONSISTS OF COLLECTING THE
HUSBAND’S SPERM AND INJECTING IT
INTO HIS WIFE’S REPRODUCTIVE TRACT
VIA THE VAGINA AT THE APPROPRIATE
STAGE OF THE MENSTRUAL PERIOD.
6. Page 6
REASONS WHY COUPLE SEEK THIS
PROCEDURE:
1.1 The husband may be fertile but
unable to participate in normal sexual
relations;
1.2 The husband may have a low sperm
count.
1.3 The husband may use AIH as a
precautionary measure.
7. Page 7
• Does not destroy the personal and
sexual aspects of the marriage bond
and thus has been less criticized.
• Few legal concerns over the method.
• Few theological concerns except for
masturbation.
8. Page 8
2. ARTIFICIAL INSEMINATION BY
DONOR (AID)
• Scientific aspects are the same as that of
AIH except that the sperm donor is used
instead of the husband.
• Raised a lot of questions and concerns
9. Page 9
REASONS WHY COUPLES SEEK THIS
PROCEDURE:
a. The husband might be carrying a
genetic disease that he does not want
to pass on to his child.
b. He may be sterile as a result of a
disease or accident.
10. Page 10
c. When there is some concern over the
antibody reaction from the mother
when, for example, the husband is Rh
positive and the mother is Rh
negative.
11. Page 11
2.1 Scientific considerations
• Sperm donors remain anonymous
• Accidental transmission of unknown
genetic traits
2.2 Ethical considerations
• The slippery-slope argument.
• The place of reproductive technology
in our society.