The arterial pulse is the pressure changes transmitted through the arterial wall and blood from the heart to the periphery. When the heart contracts, a pressure wave is produced on the elastic aorta wall and travels rapidly from the heart where it can be felt at peripheral arteries like the radial artery at the wrist. The central arterial pulse is transmitted to peripheral arteries depending on arterial elasticity, with more elastic arteries transmitting pulse less strongly. Pulse transmission increases with less elastic, more rigid arteries in old age. Pulse travels faster than blood flow and can be measured with accurate recording, with a delay proportional to distance from the heart.
This presentation is an overview of the description of the 4 stages of the cardiac cycle (atrial diastole, atrial systole, ventricular systole, ventricular diastole) as well as explaining the mechanism of the cardiac cycle.
This presentation is an overview of the description of the 4 stages of the cardiac cycle (atrial diastole, atrial systole, ventricular systole, ventricular diastole) as well as explaining the mechanism of the cardiac cycle.
Diastole and systole are two phases of the cardiac cycle. They occur as the heartbeats, pumping blood through a system of blood vessels that carry blood to every part of the body. Systole occurs when the heart contracts to pump blood out, and diastole occurs when the heart relaxes after contraction.
Arterial pulse (The Guyton and Hall Physiology)Maryam Fida
It is the pressure wave which travel along the walls of Arteries when blood is ejected from the left ventricle into the aorta
Aorta expands to accommodate the ejected blood volume, when it expands it has got elastic recoil, so it shortens back. This causes pressure wave which leads to expansion of arterial wall which can be palpated as arterial pulse.
Normally arterial pulse ends at arterioles.
So normally there is no capillary pulsations
FACTORS
The velocity of blood flow
The velocity of transmission of pressure wave
Diastole and systole are two phases of the cardiac cycle. They occur as the heartbeats, pumping blood through a system of blood vessels that carry blood to every part of the body. Systole occurs when the heart contracts to pump blood out, and diastole occurs when the heart relaxes after contraction.
Arterial pulse (The Guyton and Hall Physiology)Maryam Fida
It is the pressure wave which travel along the walls of Arteries when blood is ejected from the left ventricle into the aorta
Aorta expands to accommodate the ejected blood volume, when it expands it has got elastic recoil, so it shortens back. This causes pressure wave which leads to expansion of arterial wall which can be palpated as arterial pulse.
Normally arterial pulse ends at arterioles.
So normally there is no capillary pulsations
FACTORS
The velocity of blood flow
The velocity of transmission of pressure wave
Your heart is divided into four chambers. You have two chambers on the top (atrium, plural atria) and two on the bottom (ventricles), one on each side of the heart. Right atrium: Two large veins deliver oxygen-poor blood to your right atrium. The superior vena cava carries blood from your upper body.
Your heart is the main organ of your cardiovascular system, a network of blood vessels that pumps blood throughout your body. It also works with other body systems to control your heart rate and blood pressure. Your family history, personal health history and lifestyle all affect how well your heart works.
What is the heart?
The heart is a fist-sized organ that pumps blood throughout your body. It's the primary organ of your circulatory system.
Your heart contains four main sections (chambers) made of muscle and powered by electrical impulses. Your brain and nervous system direct your heart’s function.
What is the heart’s function?
Your heart’s main function is to move blood throughout your body. Your heart also:
Controls the rhythm and speed of your heart rate.
Maintains your blood pressure.
How does your heart work with other organs?
Your heart works with other body systems to control your heart rate and other body functions. The primary systems are:
Nervous system: Your nervous system helps control your heart rate. It sends signals that tell your heart to beat slower during rest and faster during stress.
Endocrine system: Your endocrine system sends out hormones. These hormones tell your blood vessels to constrict or relax, which affects your blood pressure. Hormones from your thyroid gland can also tell your heart to beat faster or slower.
Where is your heart located?
Your heart is located in the front of your chest. It sits slightly behind and to the left of your sternum (breastbone). Your ribcage protects your heart.
Where is your heart located?
Your heart is located in the front of your chest. It sits slightly behind and to the left of your sternum (breastbone). Your ribcage protects your heart.
What side is your heart on?
Your heart is slightly on the left side of your body. It sits between your right and left lungs. The left lung is slightly smaller to make room for the heart in your left chest.
On average, an adult’s heart weighs about 10 ounces. Your heart may weigh a little more or a little less, depending on your body size and sex.
What are the parts of the heart’s anatomy?
The parts of your heart are like the parts of a house. Your heart has:
Walls.
Chambers (rooms).
Valves (doors).
Blood vessels (plumbing).
Electrical conduction system (electricity).
Heart walls
Your heart walls are the muscles that contract (squeeze) and relax to send blood throughout your body. A layer of muscular tissue called the septum divides your heart walls into the left and right sides.
Your heart walls have three layers:
Endocardium: Inner layer.
Myocardium: Muscular middle layer.
Epicardium: Protective outer layer.
The epicardium is one layer of your
This presentation is a combination of different slides which I re-purposed. I included a reference of all the slides I used at the end of my presentation.
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
2. INTRODUCTION
• Arterial pulse is defined as the pressure changes
transmitted in the form of waves through arterial
wall and blood column from heart to periphery.
• When heart contracts, the blood is ejected into
aorta with great force. It causes distension of this
blood vessel and a rise in pressure. A pressure
wave is produced on the elastic wall of the aorta.
• It travels rapidly from the heart and can be felt
after a brief interval, at any superficial peripheral
artery like radial artery at wrist.
3. TRANSMISSION OF PULSE
• Central arterial pulse is transmitted to the
peripheral arteries as peripheral arterial pulse.
• Formation and transmission of pulse wave
depends upon the elasticity of blood vessels.
• Thus, when the walls of the arteries are more
distensible, the pressure rise is less and so the
transmission of pulse is less.
4. • When the arterial wall loses its elastic
property and becomes rigid as in old age, the
pressure rise is more and the transmission of
pulse is also more.
• Pulse is not transmitted to capillaries because
capillaries are devoid of elastic tissues.
5. VELOCITY OF TRANSMISSION OF
PULSE
• Average velocity at which the pulse wave is
transmitted varies between 7 and 9
meter/second.
• Pulse travels faster than the blood. Maximum
velocity of blood flow in the body (in larger
arteries) is only 50 cm/second.
6. „
DELAY IN TRANSMISSION OF PULSE
• At the arteries, pulse is felt after a short interval
from the beginning of ventricular systole.
• This delay is very small and it can be measured
only by accurate recording.
• The delay is directly proportional to the distance
from heart.
• Delay of pulse at:
1. Common carotid artery: 0.01 to 0.02 second
2. Radial artery: About 0.08 second.
8. Pulse Rate at Different Age
• In fetus : 150 to 180/minute
• At birth : 130 to 140/minute
• At 10 years of age : 90/minute
• After puberty : 72/minute.
