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AORTIC
DISSECTION!
Dr. Nikrish S Hegde
LEARNING OBJECTIVES!





Identify the two types of aortic dissection and
list the indications for treatment.

Describe the imaging parameters and the
typical and atypical imaging findings in aortic
dissections.

Discuss the imaging features of complications
that can arise from aortic dissections.
IMPORTANCE!
 Most

common

 Fatal

outcome

 Prompt

diagnosis and treatment.
AORTA
 made

of three layers, called from the
luminal side outward, the tunica intima,
the tunica media and the tunica
adventitia
What is aortic dissection?
 Dissection

is the result of a spontaneous
longitudinal separation of the aortic
intima and adventitia caused by
circulating blood gaining access to and
splitting the media of the aortic wall
TYPES:DeBakey
Standford
 Type A dissections

account for 60%–70%
of cases and typically require urgent
surgical intervention.

 Stanford

type B dissection involves the
descending thoracic aorta distal to the left
subclavian artery and accounts for 30%–
40% of cases. Management takes the
form of medical treatment of hypertension.
Indications for immediate
surgery
 Hemodynamic

instabilty.
 Uncontrolled HTN.
 Diameter > 6cm.
 Ischaemic Complications.
PRESENTATION.
 CHEST

PAIN
 SYNCOPE
 RIGHT HYPOCHONDRIAL PAIN
..ABNORMAL LFT
 OLIGURIA ..ANURIA ..ABNORMAL RFT
 NAUSEA ..VOMITING..PAIN
ABDOMEN..BLOODY DIARRHOEA..
 LOWER LIMB ISCHAEMIA
ACUTE VS CHRONIC
 The

dissection is termed acute when it is
diagnosed within 14 days after the first
symptoms appear.

 It

is termed chronic when it is diagnosed
later .
HELICAL CT AND AORTIC
DISSECTION.





Aortography.
Shorter acquisition time, wide availability, and
high diagnostic accuracy and has, therefore,
classically been the modality of choice for the
evaluation of aortic dissection.
The intimal flap, type and extent of dissection
,presence of thrombus and the presence of
associated complications and follow up
changes.
TECHNIQUE
 The

examination begins with conventional
unenhanced CT.

 Coverage

begins 2 cm above the aortic
arch and continues to the superior aspect
of the femoral head.

 We

then inject 100 mL of nonionic at a
rate of 2 mL/sec through a 20-gauge
catheter positioned in the right arm.
Helical CT is performed 30 seconds after
administration of contrast
TYPICAL AORTIC DISSECTION
 The

classic feature of aortic dissection is a
partition between the true and false
channels.
 Secondary findings include internal
displacement of intimal calcifications or a
hyperattenuating intima; delayed
enhancement of the false lumen;
widening of the aorta; and
mediastinal, pleural, or pericardial
hematoma .
STANDFORD TYPE A
STANFORD B
How do we distinguish false
lumen from the true lumen??
 SIZE
 POSITION-False

channel usually arises
anterior in the ascending aorta and spirals
to posterior and left lateral in descending
aorta.
 FLOW
 SECONDARY CHANGES – THROMBOSIS
 BEAK’S SIGN
BEAK’S SIGN
THROMBOSED FALSE LUMEN
ATYPICAL AORTIC DISSECTION
 INTRAMURAL

HEMATOMA:
Unenhanced CT shows a cuff or crescent
of high attenuation and displacement of
intimal calcifications. On enhanced CT
scans, a smooth region of low attenuation
can be seen
 Penetrating

atherosclerotic ulcer is
defined as an atherosclerotic lesion with
ulceration that penetrates the internal
elastic lamina; such penetration facilitates
hematoma formation within the media of
the aortic wall
Ruptured Type B Dissection
Atypical Configuration of the
Intimal Flap

circumferential
intimal flap
filiform
MercedesBenz sign
CHANGES DURING FOLLOW-UP
PITFALLS
 The

CT appearances of several entities
can cause them to be mistaken for
atypical AAD.
 CT

scan shows an atheromatous thrombus
with an irregular internal border in the
thoracic descending. A thrombosed
aortic dissection usually demonstrates a
smooth internal border.
N
Perivenous streaks
 combination

of beam hardening and

motion
 orientation of such streaks typically varies
from section to section and extends
beyond the confines of the aortic wall
 minimize perivenous streaks by performing
bolus injection into the right arm at a rate
of 2 mL/sec
Aortic motion artifact
 ascending

aorta and is related to
movement of the aortic wall
 artifact is seen at the left anterior and
right posterior margins of the aortic
circumference
 a serrated appearance of the left anterior
ascending aorta on two- or threedimensional reconstruction images
BRANCH VESSEL OCCLUSION
 There

are two types of branch-vessel
occlusion.

1)STATIC
2)DYNAMIC
STATIC
 the

intimal flap intersects or enters the
branch-vessel origin. Static obstruction is
treated locally with an intravascular stent
DYNAMIC
 the

intimal flap spares the branch-vessel
wall but prolapses across the branchvessel origin and covers it like a curtain .
Dynamic obstruction is treated with a
fenestration procedure
ADVANCES
TEE

MRI
TRIPLE-RULE-OUT

-CT
Transesophageal
echocardiography
 secondary

signs of an aortic dissection
such as aortic root dilatation, aortic
regurgitation, coronary ostial
patency, pericardial effusions, or regional
abnormal wall motion can be diagnosed.
 TEE can be performed in the emergency
department at the bedside of unstable
patients.
MR angiography
 suitable

for the investigation of aortic
dissection in medically stable patients or
those with chronic dissections
 including lack of nonionizing
radiation, multiplanar evaluation, and
greater vessel coverage at high resolution
with fewer sections.
 It cannot be performed in unstable
patients due to longer acquisition time
and difficulty in monitoring, and it is not
appropriate for patients with implanted
electronic devices
TRIPLE-RULE-OUT -CT
 Assess

the aorta, coronary arteries, and
pulmonary arteries and the middle and
lower portions of the lungs during a single
scan with use of several optimally timed
boluses of contrast material and ECG
gating.
 Biphasic injection of iodinated contrast
material (≤100 mL)

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Aortic Disssection. Dr Nikrish Hegde.

  • 2. LEARNING OBJECTIVES!    Identify the two types of aortic dissection and list the indications for treatment.
 Describe the imaging parameters and the typical and atypical imaging findings in aortic dissections.
 Discuss the imaging features of complications that can arise from aortic dissections.
  • 3. IMPORTANCE!  Most common  Fatal outcome  Prompt diagnosis and treatment.
  • 4. AORTA  made of three layers, called from the luminal side outward, the tunica intima, the tunica media and the tunica adventitia
  • 5. What is aortic dissection?  Dissection is the result of a spontaneous longitudinal separation of the aortic intima and adventitia caused by circulating blood gaining access to and splitting the media of the aortic wall
  • 7.
  • 8.
  • 9.  Type A dissections account for 60%–70% of cases and typically require urgent surgical intervention.  Stanford type B dissection involves the descending thoracic aorta distal to the left subclavian artery and accounts for 30%– 40% of cases. Management takes the form of medical treatment of hypertension.
  • 10. Indications for immediate surgery  Hemodynamic instabilty.  Uncontrolled HTN.  Diameter > 6cm.  Ischaemic Complications.
  • 11. PRESENTATION.  CHEST PAIN  SYNCOPE  RIGHT HYPOCHONDRIAL PAIN ..ABNORMAL LFT  OLIGURIA ..ANURIA ..ABNORMAL RFT  NAUSEA ..VOMITING..PAIN ABDOMEN..BLOODY DIARRHOEA..  LOWER LIMB ISCHAEMIA
  • 12. ACUTE VS CHRONIC  The dissection is termed acute when it is diagnosed within 14 days after the first symptoms appear.  It is termed chronic when it is diagnosed later .
  • 13. HELICAL CT AND AORTIC DISSECTION.    Aortography. Shorter acquisition time, wide availability, and high diagnostic accuracy and has, therefore, classically been the modality of choice for the evaluation of aortic dissection. The intimal flap, type and extent of dissection ,presence of thrombus and the presence of associated complications and follow up changes.
  • 14. TECHNIQUE  The examination begins with conventional unenhanced CT.  Coverage begins 2 cm above the aortic arch and continues to the superior aspect of the femoral head.  We then inject 100 mL of nonionic at a rate of 2 mL/sec through a 20-gauge catheter positioned in the right arm. Helical CT is performed 30 seconds after administration of contrast
  • 15.
  • 16. TYPICAL AORTIC DISSECTION  The classic feature of aortic dissection is a partition between the true and false channels.  Secondary findings include internal displacement of intimal calcifications or a hyperattenuating intima; delayed enhancement of the false lumen; widening of the aorta; and mediastinal, pleural, or pericardial hematoma .
  • 17.
  • 18.
  • 20.
  • 22. How do we distinguish false lumen from the true lumen??  SIZE  POSITION-False channel usually arises anterior in the ascending aorta and spirals to posterior and left lateral in descending aorta.  FLOW  SECONDARY CHANGES – THROMBOSIS  BEAK’S SIGN
  • 25. ATYPICAL AORTIC DISSECTION  INTRAMURAL HEMATOMA: Unenhanced CT shows a cuff or crescent of high attenuation and displacement of intimal calcifications. On enhanced CT scans, a smooth region of low attenuation can be seen
  • 26.
  • 27.
  • 28.
  • 29.  Penetrating atherosclerotic ulcer is defined as an atherosclerotic lesion with ulceration that penetrates the internal elastic lamina; such penetration facilitates hematoma formation within the media of the aortic wall
  • 30.
  • 31.
  • 32. Ruptured Type B Dissection
  • 33.
  • 34. Atypical Configuration of the Intimal Flap circumferential intimal flap
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.
  • 43.
  • 44.
  • 45.
  • 46.
  • 47. PITFALLS  The CT appearances of several entities can cause them to be mistaken for atypical AAD.
  • 48.
  • 49.  CT scan shows an atheromatous thrombus with an irregular internal border in the thoracic descending. A thrombosed aortic dissection usually demonstrates a smooth internal border.
  • 50.
  • 51. N
  • 52. Perivenous streaks  combination of beam hardening and motion  orientation of such streaks typically varies from section to section and extends beyond the confines of the aortic wall  minimize perivenous streaks by performing bolus injection into the right arm at a rate of 2 mL/sec
  • 53. Aortic motion artifact  ascending aorta and is related to movement of the aortic wall  artifact is seen at the left anterior and right posterior margins of the aortic circumference  a serrated appearance of the left anterior ascending aorta on two- or threedimensional reconstruction images
  • 54.
  • 55. BRANCH VESSEL OCCLUSION  There are two types of branch-vessel occlusion. 1)STATIC 2)DYNAMIC
  • 56. STATIC  the intimal flap intersects or enters the branch-vessel origin. Static obstruction is treated locally with an intravascular stent
  • 57.
  • 58.
  • 59. DYNAMIC  the intimal flap spares the branch-vessel wall but prolapses across the branchvessel origin and covers it like a curtain . Dynamic obstruction is treated with a fenestration procedure
  • 60.
  • 61.
  • 63. Transesophageal echocardiography  secondary signs of an aortic dissection such as aortic root dilatation, aortic regurgitation, coronary ostial patency, pericardial effusions, or regional abnormal wall motion can be diagnosed.  TEE can be performed in the emergency department at the bedside of unstable patients.
  • 64.
  • 65.
  • 66.
  • 67. MR angiography  suitable for the investigation of aortic dissection in medically stable patients or those with chronic dissections  including lack of nonionizing radiation, multiplanar evaluation, and greater vessel coverage at high resolution with fewer sections.  It cannot be performed in unstable patients due to longer acquisition time and difficulty in monitoring, and it is not appropriate for patients with implanted electronic devices
  • 68. TRIPLE-RULE-OUT -CT  Assess the aorta, coronary arteries, and pulmonary arteries and the middle and lower portions of the lungs during a single scan with use of several optimally timed boluses of contrast material and ECG gating.  Biphasic injection of iodinated contrast material (≤100 mL)

Editor's Notes

  1. Stanford type B aortic dissection. Contrast-enhanced CT scans obtained at different levels show a thrombosed false lumen (circle in a). Arrow in a indicates a small residual flow channel in the false lumen.
  2. these features are difficult to differentiate from those of an acutely thrombosed false lumen. An observation that may help one differentiate intramural hematoma from the thrombosed false lumen of classic intimal dissection is that the latter entity tends to spiral longitudinally around the aorta, whereas the former entity tends to maintain a constant circumferential relationship with the aortic wall (
  3. In an open dissection, these features are difficult to differentiate from those of an acutely thrombosed false lumen. An observation that may help one differentiate intramural hematoma from the thrombosed false lumen of classic intimal dissection is that the latter entity tends to spiral longitudinally around the aorta, whereas the former entity tends to maintain a constant circumferential relationship with the aortic wal
  4. Typically, penetrating atherosclerotic ulcer occurs in the middle or distal third of the thoracic aorta; CT features include a focal ulcer with adjacent subintimal hematoma (15) (Fig 8). Penetrating atherosclerotic ulcer can be differentiated from aortic dissection by means of (a) the extensive atherosclerotic disease and ectasia in penetrating atherosclerotic ulcer and (b) the lack of compression of the aortic lumen in elderly persons with penetrating atherosclerotic ulcer.