SlideShare a Scribd company logo
An Assignment on
Anti-arrhythmic Drug
University of Science and Technology Chittagong
(USTC)
Submitted by
Md. Irfan Uddin
Roll:-1083
Reg:-1086
Course No:-PHR-306
Course Title:-Pharmacology-II
Date of Submission:-31/12/20
Submitted to
Mrs. Marjina ajrin
Assistant Professor
Department of Pharmacy, University of
Science and Technology Chittagong
(USTC)
Department of Pharmacy
Arrhythmias are deviations from normal heartbeat pattern.They include
abnormalities of impulse formation,such as heart rate,rhythm,or site of impulse
origin and conduction disturbances,which disrupts the normal sequence of atrial and
ventricular activation.
Mechanism of arrhythmias:-
Three major mechanisms contribute to development of cardiac arrhythmias:
 Automaticity
 Reentry and
 Triggered activity.
Pathogenesis and inducement of arrhythmia:-
 Some physical condition
 Pathological heart disease
 Physical and chemical factors or toxicosis
 Electrolyte disturbance or acid-base imbalance.
Arrhythmia
Normal Electrical Activity in the Heart:-
Types of cardiac arrhythmias are:
MANAGEMENT
NON-PHARMACOLOGICAL
• Lifestyle changes
• Devices: Implantable cardioverter defibrillator (ICD)
• Cardioversion: This treatment can be chemical or electric
• Cardiac Ablation: A nonsurgical technique that neutralizes parts of the
abnormal electrical pathway that is causing the arrhythmia
Heart Beat Name
500 Atrial fibrillation
350 Atrial flutter
200 Paroxysmal TA
150 Simple tachyarrythmia
100
60
Normal range
40 Mild bradyarrhythmias
20 Moderate BA
• Cardiac Surgery:- Cardidc surgery is an invasive procedure where surgeons will
remove abnormal sites
Pharmacological:-
 Anti-arrhythmic drug
Quinidine
Historically, quinidine was the first antiarrhythmic drug used.
 Can cause proarrhythmic complications by prolonging the QT interval in
certain genetically predisposed individuals or by depressing conduction and
promoting reentry. Quinidine sulfate is also used to treat malaria.
INDICATIONS:-
 Maintain sinus rhythm in patients with atrial flutter or atrial fibrillation
 prevent recurrence of ventricular tachycardia or VF
Mechanism Of Action:-
side effects:-
Quinidine oral tablet doesn’t cause drowsiness, but it can cause other side effects.
More common side effects
Quinidine blocks
rapid inflow of Na+
during phase 0 of
action potential
Increased
depolarization
period
Increase action
potential
duration
Antiarrythmic
effect
The more common side effects that occur with quinidine include:
 diarrhea
 upset stomach
 lightheadedness
 headache
 tiredness
 feeling like your heart is beating faster
 chest pain
 dizziness
 skin rash
 blurred or double vision
Quinidine is contraindicated in patients with complete AV block, severe
intraventricular conduction defects, left bundle-branch block, or ventricular
ectopy.

More Related Content

What's hot

Comprehensive approach to managing heart Failure Patient
Comprehensive approach to managing heart Failure PatientComprehensive approach to managing heart Failure Patient
Comprehensive approach to managing heart Failure Patient
drucsamal
 
Perioperative management of hypertension
Perioperative management of hypertensionPerioperative management of hypertension
Perioperative management of hypertensionDrUday Pratap Singh
 
Perioperative Management
Perioperative ManagementPerioperative Management
Perioperative ManagementAndrew Ferguson
 
AHF In Critical Illness
AHF In Critical IllnessAHF In Critical Illness
AHF In Critical Illness
Muhammad Badawi
 
Acute Heart Failure
Acute Heart FailureAcute Heart Failure
Acute Heart Failure
Made Adi Satria
 
Acute decompensated heart failure
Acute decompensated heart failureAcute decompensated heart failure
Acute decompensated heart failure
Quang Huy Phạm
 
Hypertensive Emergencies
Hypertensive EmergenciesHypertensive Emergencies
Hypertensive Emergencies
Rebecca Omozuapo
 
Mgt of htn crisis by gelaye
Mgt of htn crisis  by gelayeMgt of htn crisis  by gelaye
Mgt of htn crisis by gelaye
gelaye mandefro
 
Pharmacotherapy of ca and chf
Pharmacotherapy of ca and chfPharmacotherapy of ca and chf
Pharmacotherapy of ca and chf
Saleem Cology
 
2013 sept 20_final__acute_decompensated_heart_failure
2013 sept 20_final__acute_decompensated_heart_failure2013 sept 20_final__acute_decompensated_heart_failure
2013 sept 20_final__acute_decompensated_heart_failure
drucsamal
 
Hypertensive crisis
Hypertensive crisisHypertensive crisis
Hypertensive crisis
HOSPITALPONTIANJOHOR
 
Heart Failure management in ICU
Heart Failure management in ICUHeart Failure management in ICU
Heart Failure management in ICUAhmad Y. Alansi
 
Precath preparation
Precath preparationPrecath preparation
Precath preparationFuad Farooq
 
Antihypertensives and anesthetic implications - Dr. Vaibhav
Antihypertensives and anesthetic implications  - Dr. VaibhavAntihypertensives and anesthetic implications  - Dr. Vaibhav
Antihypertensives and anesthetic implications - Dr. Vaibhav
Vaibhav Tulsyan
 
Chris Jones Acute Heart Failure
Chris Jones Acute Heart FailureChris Jones Acute Heart Failure
Chris Jones Acute Heart Failure
Peter Reed
 
Hypertensive emergencies
Hypertensive emergenciesHypertensive emergencies
Hypertensive emergencies
Myiesha Taylor
 
Management of Hypertensive Crisis
Management of Hypertensive CrisisManagement of Hypertensive Crisis
Management of Hypertensive Crisis
Shubham Agarwal
 
Hypertension and Anesthesia
Hypertension and AnesthesiaHypertension and Anesthesia
Hypertension and Anesthesia
anujkarki
 
Acute decompensated heart failure
Acute decompensated heart failureAcute decompensated heart failure
Acute decompensated heart failure
Priyanka Thakur
 

What's hot (19)

Comprehensive approach to managing heart Failure Patient
Comprehensive approach to managing heart Failure PatientComprehensive approach to managing heart Failure Patient
Comprehensive approach to managing heart Failure Patient
 
Perioperative management of hypertension
Perioperative management of hypertensionPerioperative management of hypertension
Perioperative management of hypertension
 
Perioperative Management
Perioperative ManagementPerioperative Management
Perioperative Management
 
AHF In Critical Illness
AHF In Critical IllnessAHF In Critical Illness
AHF In Critical Illness
 
Acute Heart Failure
Acute Heart FailureAcute Heart Failure
Acute Heart Failure
 
Acute decompensated heart failure
Acute decompensated heart failureAcute decompensated heart failure
Acute decompensated heart failure
 
Hypertensive Emergencies
Hypertensive EmergenciesHypertensive Emergencies
Hypertensive Emergencies
 
Mgt of htn crisis by gelaye
Mgt of htn crisis  by gelayeMgt of htn crisis  by gelaye
Mgt of htn crisis by gelaye
 
Pharmacotherapy of ca and chf
Pharmacotherapy of ca and chfPharmacotherapy of ca and chf
Pharmacotherapy of ca and chf
 
2013 sept 20_final__acute_decompensated_heart_failure
2013 sept 20_final__acute_decompensated_heart_failure2013 sept 20_final__acute_decompensated_heart_failure
2013 sept 20_final__acute_decompensated_heart_failure
 
Hypertensive crisis
Hypertensive crisisHypertensive crisis
Hypertensive crisis
 
Heart Failure management in ICU
Heart Failure management in ICUHeart Failure management in ICU
Heart Failure management in ICU
 
Precath preparation
Precath preparationPrecath preparation
Precath preparation
 
Antihypertensives and anesthetic implications - Dr. Vaibhav
Antihypertensives and anesthetic implications  - Dr. VaibhavAntihypertensives and anesthetic implications  - Dr. Vaibhav
Antihypertensives and anesthetic implications - Dr. Vaibhav
 
Chris Jones Acute Heart Failure
Chris Jones Acute Heart FailureChris Jones Acute Heart Failure
Chris Jones Acute Heart Failure
 
Hypertensive emergencies
Hypertensive emergenciesHypertensive emergencies
Hypertensive emergencies
 
Management of Hypertensive Crisis
Management of Hypertensive CrisisManagement of Hypertensive Crisis
Management of Hypertensive Crisis
 
Hypertension and Anesthesia
Hypertension and AnesthesiaHypertension and Anesthesia
Hypertension and Anesthesia
 
Acute decompensated heart failure
Acute decompensated heart failureAcute decompensated heart failure
Acute decompensated heart failure
 

Similar to Anti arrhythmic drug(pharmacology)

Heart Failure (Dr Vosik Presentation)
Heart Failure (Dr Vosik Presentation)Heart Failure (Dr Vosik Presentation)
Heart Failure (Dr Vosik Presentation)
The CRUDEM Foundation
 
Heart failure – an update [autosaved]
Heart failure – an update [autosaved]Heart failure – an update [autosaved]
Heart failure – an update [autosaved]SMSRAZA
 
Heart failure – an update
Heart failure – an updateHeart failure – an update
Heart failure – an update
SMSRAZA
 
1.0 - Hypertension - 2 hour lecture-TZ.ppt
1.0 - Hypertension - 2 hour lecture-TZ.ppt1.0 - Hypertension - 2 hour lecture-TZ.ppt
1.0 - Hypertension - 2 hour lecture-TZ.ppt
Mariah304440
 
Pharmacology antiarrhythmias
Pharmacology   antiarrhythmiasPharmacology   antiarrhythmias
Pharmacology antiarrhythmiasMBBS IMS MSU
 
Sudden cardiac death and cardiogenic shock a team approach to save heart and...
Sudden cardiac death and cardiogenic shock  a team approach to save heart and...Sudden cardiac death and cardiogenic shock  a team approach to save heart and...
Sudden cardiac death and cardiogenic shock a team approach to save heart and...
Han Naung Tun
 
Atrial fibrillation ksaus hs 2019
Atrial fibrillation ksaus hs 2019Atrial fibrillation ksaus hs 2019
Atrial fibrillation ksaus hs 2019
hospital
 
cvd.pptx
cvd.pptxcvd.pptx
cvd.pptx
WarqaaTareq1
 
11 heart failure
11 heart failure11 heart failure
11 heart failureinternalmed
 
Periodontal management of medically compromised patients.pptx
Periodontal management of medically compromised patients.pptxPeriodontal management of medically compromised patients.pptx
Periodontal management of medically compromised patients.pptx
prajjwalgahlot
 
Heart Failure Grand Rounds July 2023.pptx
Heart Failure Grand Rounds July 2023.pptxHeart Failure Grand Rounds July 2023.pptx
Heart Failure Grand Rounds July 2023.pptx
Valmiki Seecheran
 
Life threatening arrhythmias in the ICU
Life threatening arrhythmias in the ICULife threatening arrhythmias in the ICU
Life threatening arrhythmias in the ICU
Dr.Mahmoud Abbas
 
Cardioversion
CardioversionCardioversion
Cardioversion
Kifayat Khan
 
HOCM
HOCMHOCM
Antiarrhythmicdrug therapy Dr Vinay Verma
Antiarrhythmicdrug therapy       Dr Vinay Verma Antiarrhythmicdrug therapy       Dr Vinay Verma
Antiarrhythmicdrug therapy Dr Vinay Verma
Dr Harikrishna Harindran
 
HEART DISEASE & PREGNANCY.pptx
HEART DISEASE & PREGNANCY.pptxHEART DISEASE & PREGNANCY.pptx
Hypertension final
Hypertension finalHypertension final
Hypertension final
aanshika
 
Cardiovascular system arrhythmia Disorders of heart Rate and rhythm and condu...
Cardiovascular system arrhythmia Disorders of heart Rate and rhythm and condu...Cardiovascular system arrhythmia Disorders of heart Rate and rhythm and condu...
Cardiovascular system arrhythmia Disorders of heart Rate and rhythm and condu...
Srh Alshemary
 
HYPERTENSIVE CRISIS IN PEDIATRICS
HYPERTENSIVE CRISIS IN PEDIATRICSHYPERTENSIVE CRISIS IN PEDIATRICS
HYPERTENSIVE CRISIS IN PEDIATRICS
Tesfay Haile
 

Similar to Anti arrhythmic drug(pharmacology) (20)

Heart Failure (Dr Vosik Presentation)
Heart Failure (Dr Vosik Presentation)Heart Failure (Dr Vosik Presentation)
Heart Failure (Dr Vosik Presentation)
 
Heart failure – an update [autosaved]
Heart failure – an update [autosaved]Heart failure – an update [autosaved]
Heart failure – an update [autosaved]
 
Heart failure – an update
Heart failure – an updateHeart failure – an update
Heart failure – an update
 
Hypertension
HypertensionHypertension
Hypertension
 
1.0 - Hypertension - 2 hour lecture-TZ.ppt
1.0 - Hypertension - 2 hour lecture-TZ.ppt1.0 - Hypertension - 2 hour lecture-TZ.ppt
1.0 - Hypertension - 2 hour lecture-TZ.ppt
 
Pharmacology antiarrhythmias
Pharmacology   antiarrhythmiasPharmacology   antiarrhythmias
Pharmacology antiarrhythmias
 
Sudden cardiac death and cardiogenic shock a team approach to save heart and...
Sudden cardiac death and cardiogenic shock  a team approach to save heart and...Sudden cardiac death and cardiogenic shock  a team approach to save heart and...
Sudden cardiac death and cardiogenic shock a team approach to save heart and...
 
Atrial fibrillation ksaus hs 2019
Atrial fibrillation ksaus hs 2019Atrial fibrillation ksaus hs 2019
Atrial fibrillation ksaus hs 2019
 
cvd.pptx
cvd.pptxcvd.pptx
cvd.pptx
 
11 heart failure
11 heart failure11 heart failure
11 heart failure
 
Periodontal management of medically compromised patients.pptx
Periodontal management of medically compromised patients.pptxPeriodontal management of medically compromised patients.pptx
Periodontal management of medically compromised patients.pptx
 
Heart Failure Grand Rounds July 2023.pptx
Heart Failure Grand Rounds July 2023.pptxHeart Failure Grand Rounds July 2023.pptx
Heart Failure Grand Rounds July 2023.pptx
 
Life threatening arrhythmias in the ICU
Life threatening arrhythmias in the ICULife threatening arrhythmias in the ICU
Life threatening arrhythmias in the ICU
 
Cardioversion
CardioversionCardioversion
Cardioversion
 
HOCM
HOCMHOCM
HOCM
 
Antiarrhythmicdrug therapy Dr Vinay Verma
Antiarrhythmicdrug therapy       Dr Vinay Verma Antiarrhythmicdrug therapy       Dr Vinay Verma
Antiarrhythmicdrug therapy Dr Vinay Verma
 
HEART DISEASE & PREGNANCY.pptx
HEART DISEASE & PREGNANCY.pptxHEART DISEASE & PREGNANCY.pptx
HEART DISEASE & PREGNANCY.pptx
 
Hypertension final
Hypertension finalHypertension final
Hypertension final
 
Cardiovascular system arrhythmia Disorders of heart Rate and rhythm and condu...
Cardiovascular system arrhythmia Disorders of heart Rate and rhythm and condu...Cardiovascular system arrhythmia Disorders of heart Rate and rhythm and condu...
Cardiovascular system arrhythmia Disorders of heart Rate and rhythm and condu...
 
HYPERTENSIVE CRISIS IN PEDIATRICS
HYPERTENSIVE CRISIS IN PEDIATRICSHYPERTENSIVE CRISIS IN PEDIATRICS
HYPERTENSIVE CRISIS IN PEDIATRICS
 

More from MdIrfanUddin2

Antibody and its Clinical use (clinical pharmacy)
Antibody and its Clinical use (clinical pharmacy)Antibody and its Clinical use (clinical pharmacy)
Antibody and its Clinical use (clinical pharmacy)
MdIrfanUddin2
 
Anti-depressant drugs ( pharmacology-III)
Anti-depressant drugs ( pharmacology-III)Anti-depressant drugs ( pharmacology-III)
Anti-depressant drugs ( pharmacology-III)
MdIrfanUddin2
 
Derivatives of Cellulose
Derivatives of CelluloseDerivatives of Cellulose
Derivatives of Cellulose
MdIrfanUddin2
 
Local and International manufacturer profiles of gelatin capsule shell
Local and International manufacturer profiles of  gelatin capsule shellLocal and International manufacturer profiles of  gelatin capsule shell
Local and International manufacturer profiles of gelatin capsule shell
MdIrfanUddin2
 
Pharmacogenomics(biotechnology)
Pharmacogenomics(biotechnology)Pharmacogenomics(biotechnology)
Pharmacogenomics(biotechnology)
MdIrfanUddin2
 
Pharmacokinetic models(biopharmaceutics)
Pharmacokinetic models(biopharmaceutics)Pharmacokinetic models(biopharmaceutics)
Pharmacokinetic models(biopharmaceutics)
MdIrfanUddin2
 
Influence of pharmaceutical marketing on
Influence of pharmaceutical marketing onInfluence of pharmaceutical marketing on
Influence of pharmaceutical marketing on
MdIrfanUddin2
 
Anti viral properties of hydroxychloroquine(pharmacology)
Anti viral properties of hydroxychloroquine(pharmacology)Anti viral properties of hydroxychloroquine(pharmacology)
Anti viral properties of hydroxychloroquine(pharmacology)
MdIrfanUddin2
 
Sterilization by dry heat(applied microbiology)
Sterilization by dry heat(applied microbiology)Sterilization by dry heat(applied microbiology)
Sterilization by dry heat(applied microbiology)
MdIrfanUddin2
 
Pyrogen teat(lal test)
Pyrogen teat(lal test)Pyrogen teat(lal test)
Pyrogen teat(lal test)
MdIrfanUddin2
 
Pharmacogenomics(biotechnology)
Pharmacogenomics(biotechnology)Pharmacogenomics(biotechnology)
Pharmacogenomics(biotechnology)
MdIrfanUddin2
 
Humectant & surfactants(cosmetology)
Humectant & surfactants(cosmetology)Humectant & surfactants(cosmetology)
Humectant & surfactants(cosmetology)
MdIrfanUddin2
 
Factors affecting fluorescence intensity(pharmaceutical analysis)
Factors affecting fluorescence intensity(pharmaceutical analysis)Factors affecting fluorescence intensity(pharmaceutical analysis)
Factors affecting fluorescence intensity(pharmaceutical analysis)
MdIrfanUddin2
 
Drug simplification(medicinal chemistry)
Drug simplification(medicinal chemistry)Drug simplification(medicinal chemistry)
Drug simplification(medicinal chemistry)
MdIrfanUddin2
 
Care for childern ( community pharmacy)
Care for childern ( community pharmacy)Care for childern ( community pharmacy)
Care for childern ( community pharmacy)
MdIrfanUddin2
 
Mechanism of absorption(biopharma)
Mechanism of absorption(biopharma)Mechanism of absorption(biopharma)
Mechanism of absorption(biopharma)
MdIrfanUddin2
 
Sub divisions of hospital pharmacy
Sub divisions of hospital pharmacySub divisions of hospital pharmacy
Sub divisions of hospital pharmacy
MdIrfanUddin2
 
Hypoxia
HypoxiaHypoxia
Hypoxia
MdIrfanUddin2
 
Sar of tetracaine
Sar of tetracaineSar of tetracaine
Sar of tetracaine
MdIrfanUddin2
 

More from MdIrfanUddin2 (19)

Antibody and its Clinical use (clinical pharmacy)
Antibody and its Clinical use (clinical pharmacy)Antibody and its Clinical use (clinical pharmacy)
Antibody and its Clinical use (clinical pharmacy)
 
Anti-depressant drugs ( pharmacology-III)
Anti-depressant drugs ( pharmacology-III)Anti-depressant drugs ( pharmacology-III)
Anti-depressant drugs ( pharmacology-III)
 
Derivatives of Cellulose
Derivatives of CelluloseDerivatives of Cellulose
Derivatives of Cellulose
 
Local and International manufacturer profiles of gelatin capsule shell
Local and International manufacturer profiles of  gelatin capsule shellLocal and International manufacturer profiles of  gelatin capsule shell
Local and International manufacturer profiles of gelatin capsule shell
 
Pharmacogenomics(biotechnology)
Pharmacogenomics(biotechnology)Pharmacogenomics(biotechnology)
Pharmacogenomics(biotechnology)
 
Pharmacokinetic models(biopharmaceutics)
Pharmacokinetic models(biopharmaceutics)Pharmacokinetic models(biopharmaceutics)
Pharmacokinetic models(biopharmaceutics)
 
Influence of pharmaceutical marketing on
Influence of pharmaceutical marketing onInfluence of pharmaceutical marketing on
Influence of pharmaceutical marketing on
 
Anti viral properties of hydroxychloroquine(pharmacology)
Anti viral properties of hydroxychloroquine(pharmacology)Anti viral properties of hydroxychloroquine(pharmacology)
Anti viral properties of hydroxychloroquine(pharmacology)
 
Sterilization by dry heat(applied microbiology)
Sterilization by dry heat(applied microbiology)Sterilization by dry heat(applied microbiology)
Sterilization by dry heat(applied microbiology)
 
Pyrogen teat(lal test)
Pyrogen teat(lal test)Pyrogen teat(lal test)
Pyrogen teat(lal test)
 
Pharmacogenomics(biotechnology)
Pharmacogenomics(biotechnology)Pharmacogenomics(biotechnology)
Pharmacogenomics(biotechnology)
 
Humectant & surfactants(cosmetology)
Humectant & surfactants(cosmetology)Humectant & surfactants(cosmetology)
Humectant & surfactants(cosmetology)
 
Factors affecting fluorescence intensity(pharmaceutical analysis)
Factors affecting fluorescence intensity(pharmaceutical analysis)Factors affecting fluorescence intensity(pharmaceutical analysis)
Factors affecting fluorescence intensity(pharmaceutical analysis)
 
Drug simplification(medicinal chemistry)
Drug simplification(medicinal chemistry)Drug simplification(medicinal chemistry)
Drug simplification(medicinal chemistry)
 
Care for childern ( community pharmacy)
Care for childern ( community pharmacy)Care for childern ( community pharmacy)
Care for childern ( community pharmacy)
 
Mechanism of absorption(biopharma)
Mechanism of absorption(biopharma)Mechanism of absorption(biopharma)
Mechanism of absorption(biopharma)
 
Sub divisions of hospital pharmacy
Sub divisions of hospital pharmacySub divisions of hospital pharmacy
Sub divisions of hospital pharmacy
 
Hypoxia
HypoxiaHypoxia
Hypoxia
 
Sar of tetracaine
Sar of tetracaineSar of tetracaine
Sar of tetracaine
 

Recently uploaded

micro teaching on communication m.sc nursing.pdf
micro teaching on communication m.sc nursing.pdfmicro teaching on communication m.sc nursing.pdf
micro teaching on communication m.sc nursing.pdf
Anurag Sharma
 
THERAPEUTIC ANTISENSE MOLECULES .pptx
THERAPEUTIC ANTISENSE MOLECULES    .pptxTHERAPEUTIC ANTISENSE MOLECULES    .pptx
THERAPEUTIC ANTISENSE MOLECULES .pptx
70KRISHPATEL
 
ANATOMY AND PHYSIOLOGY OF URINARY SYSTEM.pptx
ANATOMY AND PHYSIOLOGY OF URINARY SYSTEM.pptxANATOMY AND PHYSIOLOGY OF URINARY SYSTEM.pptx
ANATOMY AND PHYSIOLOGY OF URINARY SYSTEM.pptx
Swetaba Besh
 
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERY
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYDISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERY
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERY
NEHA GUPTA
 
Top Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in IndiaTop Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in India
SwisschemDerma
 
Netter's Atlas of Human Anatomy 7.ed.pdf
Netter's Atlas of Human Anatomy 7.ed.pdfNetter's Atlas of Human Anatomy 7.ed.pdf
Netter's Atlas of Human Anatomy 7.ed.pdf
BrissaOrtiz3
 
Superficial & Deep Fascia of the NECK.pptx
Superficial & Deep Fascia of the NECK.pptxSuperficial & Deep Fascia of the NECK.pptx
Superficial & Deep Fascia of the NECK.pptx
Dr. Rabia Inam Gandapore
 
Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...
Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...
Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...
chandankumarsmartiso
 
Physiology of Chemical Sensation of smell.pdf
Physiology of Chemical Sensation of smell.pdfPhysiology of Chemical Sensation of smell.pdf
Physiology of Chemical Sensation of smell.pdf
MedicoseAcademics
 
share - Lions, tigers, AI and health misinformation, oh my!.pptx
share - Lions, tigers, AI and health misinformation, oh my!.pptxshare - Lions, tigers, AI and health misinformation, oh my!.pptx
share - Lions, tigers, AI and health misinformation, oh my!.pptx
Tina Purnat
 
263778731218 Abortion Clinic /Pills In Harare ,
263778731218 Abortion Clinic /Pills In Harare ,263778731218 Abortion Clinic /Pills In Harare ,
263778731218 Abortion Clinic /Pills In Harare ,
sisternakatoto
 
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptxEar and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Dr. Rabia Inam Gandapore
 
Journal Article Review on Rasamanikya
Journal Article Review on RasamanikyaJournal Article Review on Rasamanikya
Journal Article Review on Rasamanikya
Dr. Jyothirmai Paindla
 
Ketone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistryKetone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistry
Dhayanithi C
 
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Oleg Kshivets
 
Non-respiratory Functions of the Lungs.pdf
Non-respiratory Functions of the Lungs.pdfNon-respiratory Functions of the Lungs.pdf
Non-respiratory Functions of the Lungs.pdf
MedicoseAcademics
 
ABDOMINAL TRAUMA in pediatrics part one.
ABDOMINAL TRAUMA in pediatrics part one.ABDOMINAL TRAUMA in pediatrics part one.
ABDOMINAL TRAUMA in pediatrics part one.
drhasanrajab
 
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...
chandankumarsmartiso
 
The Electrocardiogram - Physiologic Principles
The Electrocardiogram - Physiologic PrinciplesThe Electrocardiogram - Physiologic Principles
The Electrocardiogram - Physiologic Principles
MedicoseAcademics
 
Identification and nursing management of congenital malformations .pptx
Identification and nursing management of congenital malformations .pptxIdentification and nursing management of congenital malformations .pptx
Identification and nursing management of congenital malformations .pptx
MGM SCHOOL/COLLEGE OF NURSING
 

Recently uploaded (20)

micro teaching on communication m.sc nursing.pdf
micro teaching on communication m.sc nursing.pdfmicro teaching on communication m.sc nursing.pdf
micro teaching on communication m.sc nursing.pdf
 
THERAPEUTIC ANTISENSE MOLECULES .pptx
THERAPEUTIC ANTISENSE MOLECULES    .pptxTHERAPEUTIC ANTISENSE MOLECULES    .pptx
THERAPEUTIC ANTISENSE MOLECULES .pptx
 
ANATOMY AND PHYSIOLOGY OF URINARY SYSTEM.pptx
ANATOMY AND PHYSIOLOGY OF URINARY SYSTEM.pptxANATOMY AND PHYSIOLOGY OF URINARY SYSTEM.pptx
ANATOMY AND PHYSIOLOGY OF URINARY SYSTEM.pptx
 
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERY
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYDISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERY
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERY
 
Top Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in IndiaTop Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in India
 
Netter's Atlas of Human Anatomy 7.ed.pdf
Netter's Atlas of Human Anatomy 7.ed.pdfNetter's Atlas of Human Anatomy 7.ed.pdf
Netter's Atlas of Human Anatomy 7.ed.pdf
 
Superficial & Deep Fascia of the NECK.pptx
Superficial & Deep Fascia of the NECK.pptxSuperficial & Deep Fascia of the NECK.pptx
Superficial & Deep Fascia of the NECK.pptx
 
Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...
Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...
Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...
 
Physiology of Chemical Sensation of smell.pdf
Physiology of Chemical Sensation of smell.pdfPhysiology of Chemical Sensation of smell.pdf
Physiology of Chemical Sensation of smell.pdf
 
share - Lions, tigers, AI and health misinformation, oh my!.pptx
share - Lions, tigers, AI and health misinformation, oh my!.pptxshare - Lions, tigers, AI and health misinformation, oh my!.pptx
share - Lions, tigers, AI and health misinformation, oh my!.pptx
 
263778731218 Abortion Clinic /Pills In Harare ,
263778731218 Abortion Clinic /Pills In Harare ,263778731218 Abortion Clinic /Pills In Harare ,
263778731218 Abortion Clinic /Pills In Harare ,
 
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptxEar and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
 
Journal Article Review on Rasamanikya
Journal Article Review on RasamanikyaJournal Article Review on Rasamanikya
Journal Article Review on Rasamanikya
 
Ketone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistryKetone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistry
 
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
 
Non-respiratory Functions of the Lungs.pdf
Non-respiratory Functions of the Lungs.pdfNon-respiratory Functions of the Lungs.pdf
Non-respiratory Functions of the Lungs.pdf
 
ABDOMINAL TRAUMA in pediatrics part one.
ABDOMINAL TRAUMA in pediatrics part one.ABDOMINAL TRAUMA in pediatrics part one.
ABDOMINAL TRAUMA in pediatrics part one.
 
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...
 
The Electrocardiogram - Physiologic Principles
The Electrocardiogram - Physiologic PrinciplesThe Electrocardiogram - Physiologic Principles
The Electrocardiogram - Physiologic Principles
 
Identification and nursing management of congenital malformations .pptx
Identification and nursing management of congenital malformations .pptxIdentification and nursing management of congenital malformations .pptx
Identification and nursing management of congenital malformations .pptx
 

Anti arrhythmic drug(pharmacology)

  • 1. An Assignment on Anti-arrhythmic Drug University of Science and Technology Chittagong (USTC) Submitted by Md. Irfan Uddin Roll:-1083 Reg:-1086 Course No:-PHR-306 Course Title:-Pharmacology-II Date of Submission:-31/12/20 Submitted to Mrs. Marjina ajrin Assistant Professor Department of Pharmacy, University of Science and Technology Chittagong (USTC) Department of Pharmacy
  • 2. Arrhythmias are deviations from normal heartbeat pattern.They include abnormalities of impulse formation,such as heart rate,rhythm,or site of impulse origin and conduction disturbances,which disrupts the normal sequence of atrial and ventricular activation. Mechanism of arrhythmias:- Three major mechanisms contribute to development of cardiac arrhythmias:  Automaticity  Reentry and  Triggered activity. Pathogenesis and inducement of arrhythmia:-  Some physical condition  Pathological heart disease  Physical and chemical factors or toxicosis  Electrolyte disturbance or acid-base imbalance. Arrhythmia Normal Electrical Activity in the Heart:-
  • 3.
  • 4. Types of cardiac arrhythmias are: MANAGEMENT NON-PHARMACOLOGICAL • Lifestyle changes • Devices: Implantable cardioverter defibrillator (ICD) • Cardioversion: This treatment can be chemical or electric • Cardiac Ablation: A nonsurgical technique that neutralizes parts of the abnormal electrical pathway that is causing the arrhythmia Heart Beat Name 500 Atrial fibrillation 350 Atrial flutter 200 Paroxysmal TA 150 Simple tachyarrythmia 100 60 Normal range 40 Mild bradyarrhythmias 20 Moderate BA
  • 5. • Cardiac Surgery:- Cardidc surgery is an invasive procedure where surgeons will remove abnormal sites Pharmacological:-  Anti-arrhythmic drug
  • 6. Quinidine Historically, quinidine was the first antiarrhythmic drug used.  Can cause proarrhythmic complications by prolonging the QT interval in certain genetically predisposed individuals or by depressing conduction and promoting reentry. Quinidine sulfate is also used to treat malaria. INDICATIONS:-  Maintain sinus rhythm in patients with atrial flutter or atrial fibrillation  prevent recurrence of ventricular tachycardia or VF
  • 7. Mechanism Of Action:- side effects:- Quinidine oral tablet doesn’t cause drowsiness, but it can cause other side effects. More common side effects Quinidine blocks rapid inflow of Na+ during phase 0 of action potential Increased depolarization period Increase action potential duration Antiarrythmic effect
  • 8. The more common side effects that occur with quinidine include:  diarrhea  upset stomach  lightheadedness  headache  tiredness  feeling like your heart is beating faster  chest pain  dizziness  skin rash  blurred or double vision Quinidine is contraindicated in patients with complete AV block, severe intraventricular conduction defects, left bundle-branch block, or ventricular ectopy.