Anisometropia is a condition where the two eyes have unequal refractive power, with a difference of more than 4 diopters not being well tolerated. There are three possibilities for binocular vision with anisometropia: binocular single vision with small differences of less than 3 diopters; uniocular vision where one eye is suppressed with high refractive errors; and alternate vision where one eye is emmetropic for distance and the other myopic for near. Diagnosis involves retinoscopy and tests like the Friend test or Worth's four dot test to determine the state of binocular vision.