Asthenopia is a condition characterized by ocular discomfort, headaches, and fatigue after near work, often due to factors like uncorrected refractive errors, ocular motility defects, and accommodation insufficiencies. Symptoms include eye tiredness, headaches, and visual disturbances, with management strategies focusing on refraction, orthoptic exercises, prism therapy, and improved nutrition. Effective treatment aims to alleviate symptoms and enhance visual function.