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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 04 Issue: 11 | Nov -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 6.171 | ISO 9001:2008 Certified Journal | Page 454
An Investigation On Myocardial Infract Localization In Medical Images
Anaswara R1, Dhanya Sreedharan2
1Anaswara R: PG Scholar, Dept. of Computer Science and Engineering, SBCE Pattoor, Kerala, India
2Dhanya Sreedharan: Professor, Dept. of Computer Science and Engineering, SBCE Pattoor, Kerala, India
---------------------------------------------------------------------***---------------------------------------------------------------------
Abstract - Myocardial infarction (MI) or acute myocardial
infarction commonly known as heart attack is one of the
major causes of cardiac death widely. It occurs due to the non
adequate blood supply of the heart area and cause death of
heart tissue. Early detection of MI will help to prevent the
infarct expansion leading to left ventricle(LV)remodeling and
high damage to the cardiac muscles. Thissurvey introducesan
different algorithms that can be used to localize and quantify
myocardial infarct from deformation of wall.
Keywords: Speckle tracking, Biomechanical modeling,
Dimensionality reduction, Myocardial Infarct
1. INTRODUCTION
Timely identification of MI and reduce the time and cost.
Echocardiography images are widely used to assess the
differential diagnosis of normal and infarcted myocardium.
The infarct localization from the wall deformation is a
common method used. The localization of infarct from
medical imaging modalities such as MRI, ECG, US are
proposed. ECG gives the accurate output with moderate cost.
The remaining part of the paper is organized as
follows: In Section II survey of all methods will be described
in detail. The paper concludes with a brief summary in
section III.
2. LITERATURE SURVEY
The ability of strain by Doppler and by speckle tracking
echocardiography [1] in the acute phase in patients with ST-
segment elevation myocardial infarction (STEMI) to
diagnose left ventricular (LV) infarct size is proposed. Also
the cardiac cycle strain should be measured. On a segmental
level, circumferential strain separated transmural from
subendocardial necrosis is proposed. LV global peak systolic
speckle strain should be the preferred method, which is for
predicting final LV infarct size.
Myocardial Infarction leads to changes in the geometry
(remodeling) of the left ventricle (LV) of the heart. A novel
analysis framework for characterizing remodeling after
myocardial infarction, using LV shape descriptors derived
from atlas-based shape models is proposed.A logistic
regression analysis [2] was performed to determine the
modes of shape variation most associated with myocardial
infarction is proposed. The results obtained from end-
diastolic and end-systolic shapes werecomparedagainst the
traditional clinical indices of remodeling: end-diastolic
volume, end-systolic volume and LV mass. The combination
of end-diastolic and end-systolic shape parameter analysis
achieved the lowest deviance, is proposed. These features
enable quantification of the amount of remodeling.
The aim of this paper is to provide a framework for
automatic scoring [3] to alert the diagnostician to potential
regions of abnormality. We investigated differentshapeand
motion configurations ofa finite-elementcardiacatlasof the
left ventricle. In this system wall motion by computer
assistance and infarct scoring has the ability to provide
robust identification of those segments requiring further
clinical investigation is proposed.
Compared with global measurements such as ejection
fraction, regional myocardial deformation can better aid
detection of cardiac dysfunction. Although tagged and
strain-encoded MR images can provide such regional
information, they are uncommon in clinical routine. In
contrast, cardiac CT images are more common with lower
cost, but only provide motion of cardiac boundaries and
additional constraints are required to obtain the myocardial
strains. To verify the potential of contrast-enhanced CT
images on computer-aided infarction identification, we
propose a biomechanical approach combined with the
support vector machine (SVM) [4].
A machine-learning algorithmfor theautomaticlocalization
of myocardial infarct in the left ventricle is proposed. Our
method constructs neighbourhood approximation forests,
[5] which are trained with previously diagnosed 4D cardiac
sequences. We introduce a new set of features that
simultaneously exploit information from the shape and
motion of the myocardial wall along the cardiac cycle. More
precisely, characteristics are extracted froma hypersurface
that represents the profile of the myocardial thickness.
We propose a novel framework to predict the location of a
myocardial infarct from local wall deformation data. Non-
linear dimensionality reduction [6] is used to estimate the
Euclidean space of coordinates encoding deformation
patterns. They consist in (i) finding the low-dimensional
coordinatesassociatedtothe measureddeformationpattern,
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 04 Issue: 11 | Nov -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 6.171 | ISO 9001:2008 Certified Journal | Page 455
and (ii) estimating the possible infarct locationassociated to
these coordinates.
Infarct size has been recognized as a good indicator of the
functional status of the ischemic heart and to evaluate the
impact of myocardial infarction therapies. Its assessment
can be performed from late gadolinium enhancement
magnetic resonance images. A number of methods have
been proposed for the semi-automatic and automatic
quantification of necrosis. We developed an automatic
method based on a Markov random field framework[7] and
a region growing approach within an EM optimization,
which enables segmentation of both necrosis and
microvascular obstructions.
3. CONCLUSION
This survey has been performed for collecting the different
algorithms for myocardial infarct localization. In this
myocardial deformation from local wall is considered. The
localization of myocardial infarct is crucial for early patient
diagnosis. This survey helps in identifying all possible
localization systems for myocardial infarction.
ACKNOWLEDGEMENT
I am grateful to my project guide Asst. Prof. Dhanya.
Sreedharan for her remarks, suggestions and for providing
all the vital facilities like providing the Internet access and
important books, which were essential. I am also thankful to
all the staff members of the Department.
REFERENCES
[1] B. Sjøli, S. Ørn, B. Grenne, H. Ihlen, T. Edvardsen, and H.
Brunvand, “Diagnostic capability and reproducibility of
strain by Doppler and by speckle tracking in patients with
acute myocardial infarction,” JACC Cardiovasc Imaging, vol.
2, pp. 24–33, 2009.
[2] X. Zhang, B. Cowan, D. Bluemke, J. Finn, C. Fonseca, A.
Kadish, D. Lee, J. Lima, A. Suinesiaputra, A. Young, and P.
Medrano-Gracia, “Atlas-based quantification of cardiac
remodeling due to myocardial infarction,”PLoSOne,vol. 9,p.
e110243, 2014.
[3] P. Medrano-Gracia, A. Suinesiaputra, B. Cowan, D.
Bluemke, A. Frangi, D. Lee, J. Lima, and A.Young,“Anatlasfor
cardiac MRI regional wall motion and infarct scoring,” in
MICCAI-STACOM, LNCS 7746, 2013, pp. 188–97.
[4] K. Wong, M. Tee, M. Chen, D. Bluemke, R. Summers, and J.
Yao, “Computer-aided infarction identification from cardiac
CT images: a biomechanical approach with SVM,” in MICCAI,
LNCS 9350, 2015, pp. 144–51.
[5] H. Bleton, J. Margeta, H. Lombaert, H. Delingette, and N.
Ayache, “Myocardial infarct localization using
neighbourhood approximation forests,”inMICCAI-STACOM,
LNCS 9534, 2016, pp. 108–16.
[6] N. Duchateau and M. Sermesant, “Prediction of infarct
localization from myocardial deformation,” in MICCAI-
STACOM, LNCS 9534, 2016, pp. 51–9.
[7] M. Viallon, J. Spaltenstein, C. de Bourguignon, C.
Vandroux, A. Ammor, W. Romero, O. Bernard, P. Croisille,
and P. Clarysse, “Automated quantification of myocardial
infarction using a hidden Markov random field model and
the EM algorithm,” in FIMH, LNCS 9126, 2015, pp. 256–64.
BIOGRAPHIES
Anaswara R received B.Tech. degree
in Computer Science and Engineering
from Mahathma Gandhi University,
India.Pursuing M.Tech. degree in
Computer Science and Engineering
from Kerala Technical University,
India.
Dhanya sreedharan received B.Tech. Degree in Computer
Science and Engineering from College of Engineering
Karunagappally (CUSAT), received M.Tech. Degree in
Computer and Information Technology from MS University,
India. Currently, she is Assistant Professor, Department of
Computer Science and Engineering, Sree Buddha College
Engineering, Kerala University.
r

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An Investigation on Myocardial Infract Localization in Medical Images

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 04 Issue: 11 | Nov -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 6.171 | ISO 9001:2008 Certified Journal | Page 454 An Investigation On Myocardial Infract Localization In Medical Images Anaswara R1, Dhanya Sreedharan2 1Anaswara R: PG Scholar, Dept. of Computer Science and Engineering, SBCE Pattoor, Kerala, India 2Dhanya Sreedharan: Professor, Dept. of Computer Science and Engineering, SBCE Pattoor, Kerala, India ---------------------------------------------------------------------***--------------------------------------------------------------------- Abstract - Myocardial infarction (MI) or acute myocardial infarction commonly known as heart attack is one of the major causes of cardiac death widely. It occurs due to the non adequate blood supply of the heart area and cause death of heart tissue. Early detection of MI will help to prevent the infarct expansion leading to left ventricle(LV)remodeling and high damage to the cardiac muscles. Thissurvey introducesan different algorithms that can be used to localize and quantify myocardial infarct from deformation of wall. Keywords: Speckle tracking, Biomechanical modeling, Dimensionality reduction, Myocardial Infarct 1. INTRODUCTION Timely identification of MI and reduce the time and cost. Echocardiography images are widely used to assess the differential diagnosis of normal and infarcted myocardium. The infarct localization from the wall deformation is a common method used. The localization of infarct from medical imaging modalities such as MRI, ECG, US are proposed. ECG gives the accurate output with moderate cost. The remaining part of the paper is organized as follows: In Section II survey of all methods will be described in detail. The paper concludes with a brief summary in section III. 2. LITERATURE SURVEY The ability of strain by Doppler and by speckle tracking echocardiography [1] in the acute phase in patients with ST- segment elevation myocardial infarction (STEMI) to diagnose left ventricular (LV) infarct size is proposed. Also the cardiac cycle strain should be measured. On a segmental level, circumferential strain separated transmural from subendocardial necrosis is proposed. LV global peak systolic speckle strain should be the preferred method, which is for predicting final LV infarct size. Myocardial Infarction leads to changes in the geometry (remodeling) of the left ventricle (LV) of the heart. A novel analysis framework for characterizing remodeling after myocardial infarction, using LV shape descriptors derived from atlas-based shape models is proposed.A logistic regression analysis [2] was performed to determine the modes of shape variation most associated with myocardial infarction is proposed. The results obtained from end- diastolic and end-systolic shapes werecomparedagainst the traditional clinical indices of remodeling: end-diastolic volume, end-systolic volume and LV mass. The combination of end-diastolic and end-systolic shape parameter analysis achieved the lowest deviance, is proposed. These features enable quantification of the amount of remodeling. The aim of this paper is to provide a framework for automatic scoring [3] to alert the diagnostician to potential regions of abnormality. We investigated differentshapeand motion configurations ofa finite-elementcardiacatlasof the left ventricle. In this system wall motion by computer assistance and infarct scoring has the ability to provide robust identification of those segments requiring further clinical investigation is proposed. Compared with global measurements such as ejection fraction, regional myocardial deformation can better aid detection of cardiac dysfunction. Although tagged and strain-encoded MR images can provide such regional information, they are uncommon in clinical routine. In contrast, cardiac CT images are more common with lower cost, but only provide motion of cardiac boundaries and additional constraints are required to obtain the myocardial strains. To verify the potential of contrast-enhanced CT images on computer-aided infarction identification, we propose a biomechanical approach combined with the support vector machine (SVM) [4]. A machine-learning algorithmfor theautomaticlocalization of myocardial infarct in the left ventricle is proposed. Our method constructs neighbourhood approximation forests, [5] which are trained with previously diagnosed 4D cardiac sequences. We introduce a new set of features that simultaneously exploit information from the shape and motion of the myocardial wall along the cardiac cycle. More precisely, characteristics are extracted froma hypersurface that represents the profile of the myocardial thickness. We propose a novel framework to predict the location of a myocardial infarct from local wall deformation data. Non- linear dimensionality reduction [6] is used to estimate the Euclidean space of coordinates encoding deformation patterns. They consist in (i) finding the low-dimensional coordinatesassociatedtothe measureddeformationpattern,
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 04 Issue: 11 | Nov -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 6.171 | ISO 9001:2008 Certified Journal | Page 455 and (ii) estimating the possible infarct locationassociated to these coordinates. Infarct size has been recognized as a good indicator of the functional status of the ischemic heart and to evaluate the impact of myocardial infarction therapies. Its assessment can be performed from late gadolinium enhancement magnetic resonance images. A number of methods have been proposed for the semi-automatic and automatic quantification of necrosis. We developed an automatic method based on a Markov random field framework[7] and a region growing approach within an EM optimization, which enables segmentation of both necrosis and microvascular obstructions. 3. CONCLUSION This survey has been performed for collecting the different algorithms for myocardial infarct localization. In this myocardial deformation from local wall is considered. The localization of myocardial infarct is crucial for early patient diagnosis. This survey helps in identifying all possible localization systems for myocardial infarction. ACKNOWLEDGEMENT I am grateful to my project guide Asst. Prof. Dhanya. Sreedharan for her remarks, suggestions and for providing all the vital facilities like providing the Internet access and important books, which were essential. I am also thankful to all the staff members of the Department. REFERENCES [1] B. Sjøli, S. Ørn, B. Grenne, H. Ihlen, T. Edvardsen, and H. Brunvand, “Diagnostic capability and reproducibility of strain by Doppler and by speckle tracking in patients with acute myocardial infarction,” JACC Cardiovasc Imaging, vol. 2, pp. 24–33, 2009. [2] X. Zhang, B. Cowan, D. Bluemke, J. Finn, C. Fonseca, A. Kadish, D. Lee, J. Lima, A. Suinesiaputra, A. Young, and P. Medrano-Gracia, “Atlas-based quantification of cardiac remodeling due to myocardial infarction,”PLoSOne,vol. 9,p. e110243, 2014. [3] P. Medrano-Gracia, A. Suinesiaputra, B. Cowan, D. Bluemke, A. Frangi, D. Lee, J. Lima, and A.Young,“Anatlasfor cardiac MRI regional wall motion and infarct scoring,” in MICCAI-STACOM, LNCS 7746, 2013, pp. 188–97. [4] K. Wong, M. Tee, M. Chen, D. Bluemke, R. Summers, and J. Yao, “Computer-aided infarction identification from cardiac CT images: a biomechanical approach with SVM,” in MICCAI, LNCS 9350, 2015, pp. 144–51. [5] H. Bleton, J. Margeta, H. Lombaert, H. Delingette, and N. Ayache, “Myocardial infarct localization using neighbourhood approximation forests,”inMICCAI-STACOM, LNCS 9534, 2016, pp. 108–16. [6] N. Duchateau and M. Sermesant, “Prediction of infarct localization from myocardial deformation,” in MICCAI- STACOM, LNCS 9534, 2016, pp. 51–9. [7] M. Viallon, J. Spaltenstein, C. de Bourguignon, C. Vandroux, A. Ammor, W. Romero, O. Bernard, P. Croisille, and P. Clarysse, “Automated quantification of myocardial infarction using a hidden Markov random field model and the EM algorithm,” in FIMH, LNCS 9126, 2015, pp. 256–64. BIOGRAPHIES Anaswara R received B.Tech. degree in Computer Science and Engineering from Mahathma Gandhi University, India.Pursuing M.Tech. degree in Computer Science and Engineering from Kerala Technical University, India. Dhanya sreedharan received B.Tech. Degree in Computer Science and Engineering from College of Engineering Karunagappally (CUSAT), received M.Tech. Degree in Computer and Information Technology from MS University, India. Currently, she is Assistant Professor, Department of Computer Science and Engineering, Sree Buddha College Engineering, Kerala University. r