In organic chemistry, an alkene is an unsaturated hydrocarbon that contains at least one carbon–carbon double bond. The words alkene and olefin are often used interchangeably.
The document discusses several methods for preparing alkanes:
1) Sabatier and Senderens reactions involve treating alkenes or alkynes with hydrogen in the presence of nickel to produce alkanes.
2) Decarboxylation of sodium carboxylate salts involves heating with sodalime to produce alkanes and carbon dioxide.
3) Reduction of alkyl halides with nascent hydrogen produces alkanes and hydrogen halides.
4) Reduction of alcohols, aldehydes, ketones, and carboxylic acids with hydriodic acid and phosphorus yields alkanes.
5) The Wurtz reaction uses sodium metal to couple two alkyl halides
Alkynes are unsaturated hydrocarbons containing a carbon-carbon triple bond. They are more unsaturated than alkenes. Alkynes undergo characteristic reactions including addition reactions, oxidation, hydration, and polymerization. They can be prepared through methods such as the dehydrogenation of tetrahalides, dehydrohalogenation of vicinal dihalides, and the reaction of sodium acetylides with primary alkyl halides.
Alkenes are hydrocarbons containing at least one carbon-carbon double bond. They have lower melting and boiling points than alkanes due to weaker intermolecular forces. The number of carbons determines an alkene's name and formula. Alkenes undergo addition reactions, combustion reactions, polymerization reactions, and can be used to test for double bonds. They differ from alkanes in bonding, reactivity and ability to cause soot during combustion. Isomers are compounds with the same molecular formula but different structural formulas, resulting in different physical but same chemical properties.
This document discusses alkenes, including:
1. Alkenes have one or more double bonds between carbon atoms and are named using IUPAC rules based on carbon chain length and double bond position.
2. Physical properties of alkenes include higher boiling points with increased carbon chain length and lower boiling points for branched isomers due to decreased intermolecular forces.
3. Alkenes undergo electrophilic addition reactions due to the electron density of the carbon-carbon double bond, allowing attack by electrophiles to form carbocations and adding nucleophiles in a stepwise mechanism.
This document provides information about carboxylic acids and carboxylic acid derivatives (esters). It discusses the properties, structures, nomenclature, preparation methods, and reactions of carboxylic acids and esters. Key points include:
- Carboxylic acids contain a carboxyl group consisting of a carbonyl and hydroxyl group attached to the same carbon. They have higher boiling points than similar molecules due to hydrogen bonding.
- Esters are carboxylic acid derivatives where the hydroxyl hydrogen is replaced by an alkyl or aryl group. They have pleasant aromas and are slightly soluble in water.
- Carboxylic acids and esters undergo acid-base reactions, esterification,
The benzoin addition is an addition reaction involving two aldehydes. The reaction generally occurs between aromatic aldehydes or glyoxals. The reaction produces an acyloin. In the classic application benzaldehyde is converted to benzoin
This document provides an overview of alkynes, including their structure, nomenclature, properties, reactions, and synthesis. Key points include:
- Alkynes contain a triple bond consisting of two pi bonds and one sigma bond, giving them a linear structure.
- They undergo addition reactions due to their relatively weak pi bonds. Common additions include hydrohalogenation, hydration, halogenation, and hydroboration-oxidation.
- Acetylide ions, formed by deprotonation of terminal alkynes, are strong nucleophiles that react through substitution and addition reactions.
Alkenes and their preparation-HYDROCARBONS PART 2ritik
Alkenes can be prepared through various methods including reduction of alkynes, dehydrohalogenation of alkyl halides, dehydration of alcohols, and heating vicinal dihalogen derivatives with zinc dust. Addition reactions of alkenes follow Markovnikov's rule or anti-Markovnikov's rule in the presence of peroxides. Alkenes undergo addition reactions with halogens, hydrogen halides, water, sulfuric acid and undergo oxidation, ozonolysis, and polymerization.
The document discusses several methods for preparing alkanes:
1) Sabatier and Senderens reactions involve treating alkenes or alkynes with hydrogen in the presence of nickel to produce alkanes.
2) Decarboxylation of sodium carboxylate salts involves heating with sodalime to produce alkanes and carbon dioxide.
3) Reduction of alkyl halides with nascent hydrogen produces alkanes and hydrogen halides.
4) Reduction of alcohols, aldehydes, ketones, and carboxylic acids with hydriodic acid and phosphorus yields alkanes.
5) The Wurtz reaction uses sodium metal to couple two alkyl halides
Alkynes are unsaturated hydrocarbons containing a carbon-carbon triple bond. They are more unsaturated than alkenes. Alkynes undergo characteristic reactions including addition reactions, oxidation, hydration, and polymerization. They can be prepared through methods such as the dehydrogenation of tetrahalides, dehydrohalogenation of vicinal dihalides, and the reaction of sodium acetylides with primary alkyl halides.
Alkenes are hydrocarbons containing at least one carbon-carbon double bond. They have lower melting and boiling points than alkanes due to weaker intermolecular forces. The number of carbons determines an alkene's name and formula. Alkenes undergo addition reactions, combustion reactions, polymerization reactions, and can be used to test for double bonds. They differ from alkanes in bonding, reactivity and ability to cause soot during combustion. Isomers are compounds with the same molecular formula but different structural formulas, resulting in different physical but same chemical properties.
This document discusses alkenes, including:
1. Alkenes have one or more double bonds between carbon atoms and are named using IUPAC rules based on carbon chain length and double bond position.
2. Physical properties of alkenes include higher boiling points with increased carbon chain length and lower boiling points for branched isomers due to decreased intermolecular forces.
3. Alkenes undergo electrophilic addition reactions due to the electron density of the carbon-carbon double bond, allowing attack by electrophiles to form carbocations and adding nucleophiles in a stepwise mechanism.
This document provides information about carboxylic acids and carboxylic acid derivatives (esters). It discusses the properties, structures, nomenclature, preparation methods, and reactions of carboxylic acids and esters. Key points include:
- Carboxylic acids contain a carboxyl group consisting of a carbonyl and hydroxyl group attached to the same carbon. They have higher boiling points than similar molecules due to hydrogen bonding.
- Esters are carboxylic acid derivatives where the hydroxyl hydrogen is replaced by an alkyl or aryl group. They have pleasant aromas and are slightly soluble in water.
- Carboxylic acids and esters undergo acid-base reactions, esterification,
The benzoin addition is an addition reaction involving two aldehydes. The reaction generally occurs between aromatic aldehydes or glyoxals. The reaction produces an acyloin. In the classic application benzaldehyde is converted to benzoin
This document provides an overview of alkynes, including their structure, nomenclature, properties, reactions, and synthesis. Key points include:
- Alkynes contain a triple bond consisting of two pi bonds and one sigma bond, giving them a linear structure.
- They undergo addition reactions due to their relatively weak pi bonds. Common additions include hydrohalogenation, hydration, halogenation, and hydroboration-oxidation.
- Acetylide ions, formed by deprotonation of terminal alkynes, are strong nucleophiles that react through substitution and addition reactions.
Alkenes and their preparation-HYDROCARBONS PART 2ritik
Alkenes can be prepared through various methods including reduction of alkynes, dehydrohalogenation of alkyl halides, dehydration of alcohols, and heating vicinal dihalogen derivatives with zinc dust. Addition reactions of alkenes follow Markovnikov's rule or anti-Markovnikov's rule in the presence of peroxides. Alkenes undergo addition reactions with halogens, hydrogen halides, water, sulfuric acid and undergo oxidation, ozonolysis, and polymerization.
Electrophilic additions involve reactions of alkenes where the pi electrons in the double bond attack an electrophile. There are several types of additions including addition of HX, halogens, water, alcohols, and hydroboration. The mechanism typically involves formation of a carbocation intermediate that is then attacked by the nucleophile. Addition occurs regioselectively according to Markovnikov's rule, favoring the most stable carbocation. Exceptions include free radical additions, which give the anti-Markovnikov product. Oxymercuration-demercuration and hydroboration allow for Markovnikov addition without rearrangements.
Grignard reagents are organomagnesium compounds formed by the reaction of an organic halide and magnesium. The reaction proceeds through single electron transfers where radicals are converted to carbanions. Grignard reagents are strong nucleophiles similar to organolithium reagents that can form new carbon-carbon bonds. They were analyzed by decomposing ethylmagnesium iodide with sulfuric acid and directing steam through the apparatus to drive off any ethane, proving it did not appreciably dissolve under experimental conditions.
This document provides an overview of electrophilic substitution reactions. It defines electrophilic substitution as a reaction where a functional group is attached to a compound by replacing another functional group, often a hydrogen atom. It describes two main types: electrophilic aromatic substitution reactions, where an atom attached to an aromatic ring is replaced; and electrophilic aliphatic substitution reactions, where hydrogen in an aliphatic compound is usually replaced. The document also outlines the three step mechanism of electrophilic substitution reactions: 1) generating an electrophile, 2) forming a carbocation, and 3) eliminating a proton to restore aromaticity.
Preparation and reaction of aldehyde and ketone, electromeric effect, aldol condensation, cannizarro reaction, perkin condensation, benzoin condensation, nucleophilic addition reaction and uses of aldehyde and ketone
This document summarizes key information about alkenes (olefins):
1) Alkenes contain carbon-carbon double bonds and are classified as unsaturated hydrocarbons. Common examples include ethylene and propene.
2) Alkenes undergo characteristic reactions such as addition of halogens, hydrogenation to form alkanes, hydration and polymerization. Many of these reactions follow Markovnikov's rule.
3) Alkenes are industrially important as monomers for polymers like polyethylene, polypropylene, PVC and polystyrene. Ethylene and propylene are the largest volume organic chemicals produced.
The document discusses aldol condensation, an organic reaction where two molecules of an aldehyde or ketone undergo a condensation reaction in the presence of a base to yield a β–hydroxyaldehyde or β–hydroxyketone. It involves the reaction of an enolate ion, formed from deprotonation of an aldehyde, with a carbonyl compound to form an aldol. This may then undergo dehydration to form a conjugated enone. The mechanism proceeds through enolate formation, carbon-carbon bond formation between the enolate and carbonyl, and protonation to form the aldol intermediate. Crossed aldol condensation refers to the reaction between two different aldehyde or ketone
Alkanes are a family of hydrocarbons whose members contain only single carbon-hydrogen bonds. The document discusses the structure, properties, conformations, and reactions of several alkanes including methane, ethane, propane, butane, and higher alkanes. It also covers topics such as torsional strain, Grignard reagents, halogenation reactions, and IUPAC nomenclature rules for naming alkanes.
The first 4 alkanes are gases, the next 13 are liquids, and higher alkanes after C18 are waxy solids. Alkanes are nonpolar and insoluble in water but soluble in nonpolar solvents. The boiling point of alkanes increases with molecular weight in a steady manner, while the melting point does not. Density also increases with larger alkane molecules. Branched chain alkanes have lower boiling points than their straight chain isomers.
Aldehydes and ketones are organic compounds which incorporate a carbonyl functional group, C=O. The carbon atom of this group has two remaining bonds that may be occupied by hydrogen or alkyl or aryl substituents. If at least one of these substituents is hydrogen, the compound is an aldehyde.
This document discusses aromatic compounds and Hückel's rule for aromaticity. It defines aromatic compounds as cyclic, planar and fully conjugated compounds that have 4n + 2 π electrons according to Hückel's rule. These compounds are highly stable due to delocalization of π electrons over the whole ring. They undergo substitution rather than addition reactions and have intermediate bond lengths and diatropic NMR properties. Anti-aromatic compounds have 4n π electrons and show the opposite NMR characteristics. Molecular orbital theory is used to explain the stability and properties of aromatic compounds.
Alkenes are a class of hydrocarbons (e.g, containing only carbon and hydrogen) unsaturated compounds with at least one carbon-to-carbon double bond. Another term used to describe alkenes is olefins. Alkenes are more reactive than alkanes due to the presence of the double bond.
The document discusses the Diels-Alder reaction, which involves a diene reacting with a dienophile to form a six-membered ring. Key characteristics include versatility, stereoselectivity, and reversibility. The mechanism involves overlap of the HOMO of the diene and LUMO of the dienophile. The stereochemistry of products is governed by the cis principle and endo rule. Variations include retro Diels-Alder reactions and cycloadditions involving allyl cations/anions.
molecular rearrangement introduction which includes nucleophilic, electrophilic, and free radical rearrangement. and mechanism, applications of favorskki and benzil benzilic acid rearrangement.
Alkenes undergo addition reactions with halogens, hydrogen, and oxygen. When bromine is added to ethene, it produces dibromoethane by adding one bromine atom to each carbon in the double bond. Alkenes also react with hydrogen through hydrogenation, where hydrogen is added across the carbon-carbon double bond at 1500C with a nickel catalyst under pressure to produce the saturated alkane. When pentene undergoes hydrogenation, it forms pentane by adding hydrogen across the carbon-carbon double bond.
This document presents information about the Perkin reaction, which was discovered in the 19th century by English chemist William Henry Perkin. The Perkin reaction is an aldol condensation that converts an aromatic aldehyde and an acid anhydride to an alpha beta unsaturated cinnamic acid. It involves a four step mechanism - abstraction of alpha hydrogen from the acid anhydride, attack of the carbanion on the carbonyl carbon of benzaldehyde, an intramolecular acetyl shift, and loss of the acetate ion to form the unsaturated carboxylic acid product. The Perkin reaction is used to synthesize cinnamic acids, phytoestrogens, stilbenes, and resver
It includes reaction and it's mechanism and also applications. It contains stereochemistry of hydroboration . It also contains many exambles about hydroboration.
I hope You all like it. I hope It is very beneficial for you all. I really thought that you all get enough knowledge from this presentation. This presentation is about materials and their classifications. After you read this presentation you knowledge is not as before.
This document summarizes key information about alcohols and phenols. It discusses their structures, properties, synthesis methods, and reactions. Alcohols contain an OH group bonded to a saturated carbon. They are important solvents and intermediates. Phenol has diverse uses and gives its name to phenolic compounds. The document describes methods for synthesizing alcohols from alkenes, carbonyls, carboxylic acids, and Grignard reagents. It also outlines reactions of alcohols including dehydration, oxidation, conversion to halides, and incorporation into esters. Phenol is produced industrially from benzene sulfonic acid or chlorobenzene. Its hydroxyl group
This document discusses oxidation and various oxidizing agents. It begins by defining oxidation and reduction as the loss or gain of electrons, respectively. It then lists several common oxidizing agents including permanganates, dichromates, hypochlorous acid, chlorates, peroxides, and ozone. Specific details are provided about permanganates and how potassium permanganate can oxidize carbon atoms with pi-bonds, weak C-H bonds, and weak C-C bonds. Fuming sulfuric acid and chlorine dioxide are also discussed. The document concludes by covering liquid-phase oxidation using oxygen and examples of oxidations like acetaldehyde to acetic acid.
Electrophilic additions involve reactions of alkenes where the pi electrons in the double bond attack an electrophile. There are several types of additions including addition of HX, halogens, water, alcohols, and hydroboration. The mechanism typically involves formation of a carbocation intermediate that is then attacked by the nucleophile. Addition occurs regioselectively according to Markovnikov's rule, favoring the most stable carbocation. Exceptions include free radical additions, which give the anti-Markovnikov product. Oxymercuration-demercuration and hydroboration allow for Markovnikov addition without rearrangements.
Grignard reagents are organomagnesium compounds formed by the reaction of an organic halide and magnesium. The reaction proceeds through single electron transfers where radicals are converted to carbanions. Grignard reagents are strong nucleophiles similar to organolithium reagents that can form new carbon-carbon bonds. They were analyzed by decomposing ethylmagnesium iodide with sulfuric acid and directing steam through the apparatus to drive off any ethane, proving it did not appreciably dissolve under experimental conditions.
This document provides an overview of electrophilic substitution reactions. It defines electrophilic substitution as a reaction where a functional group is attached to a compound by replacing another functional group, often a hydrogen atom. It describes two main types: electrophilic aromatic substitution reactions, where an atom attached to an aromatic ring is replaced; and electrophilic aliphatic substitution reactions, where hydrogen in an aliphatic compound is usually replaced. The document also outlines the three step mechanism of electrophilic substitution reactions: 1) generating an electrophile, 2) forming a carbocation, and 3) eliminating a proton to restore aromaticity.
Preparation and reaction of aldehyde and ketone, electromeric effect, aldol condensation, cannizarro reaction, perkin condensation, benzoin condensation, nucleophilic addition reaction and uses of aldehyde and ketone
This document summarizes key information about alkenes (olefins):
1) Alkenes contain carbon-carbon double bonds and are classified as unsaturated hydrocarbons. Common examples include ethylene and propene.
2) Alkenes undergo characteristic reactions such as addition of halogens, hydrogenation to form alkanes, hydration and polymerization. Many of these reactions follow Markovnikov's rule.
3) Alkenes are industrially important as monomers for polymers like polyethylene, polypropylene, PVC and polystyrene. Ethylene and propylene are the largest volume organic chemicals produced.
The document discusses aldol condensation, an organic reaction where two molecules of an aldehyde or ketone undergo a condensation reaction in the presence of a base to yield a β–hydroxyaldehyde or β–hydroxyketone. It involves the reaction of an enolate ion, formed from deprotonation of an aldehyde, with a carbonyl compound to form an aldol. This may then undergo dehydration to form a conjugated enone. The mechanism proceeds through enolate formation, carbon-carbon bond formation between the enolate and carbonyl, and protonation to form the aldol intermediate. Crossed aldol condensation refers to the reaction between two different aldehyde or ketone
Alkanes are a family of hydrocarbons whose members contain only single carbon-hydrogen bonds. The document discusses the structure, properties, conformations, and reactions of several alkanes including methane, ethane, propane, butane, and higher alkanes. It also covers topics such as torsional strain, Grignard reagents, halogenation reactions, and IUPAC nomenclature rules for naming alkanes.
The first 4 alkanes are gases, the next 13 are liquids, and higher alkanes after C18 are waxy solids. Alkanes are nonpolar and insoluble in water but soluble in nonpolar solvents. The boiling point of alkanes increases with molecular weight in a steady manner, while the melting point does not. Density also increases with larger alkane molecules. Branched chain alkanes have lower boiling points than their straight chain isomers.
Aldehydes and ketones are organic compounds which incorporate a carbonyl functional group, C=O. The carbon atom of this group has two remaining bonds that may be occupied by hydrogen or alkyl or aryl substituents. If at least one of these substituents is hydrogen, the compound is an aldehyde.
This document discusses aromatic compounds and Hückel's rule for aromaticity. It defines aromatic compounds as cyclic, planar and fully conjugated compounds that have 4n + 2 π electrons according to Hückel's rule. These compounds are highly stable due to delocalization of π electrons over the whole ring. They undergo substitution rather than addition reactions and have intermediate bond lengths and diatropic NMR properties. Anti-aromatic compounds have 4n π electrons and show the opposite NMR characteristics. Molecular orbital theory is used to explain the stability and properties of aromatic compounds.
Alkenes are a class of hydrocarbons (e.g, containing only carbon and hydrogen) unsaturated compounds with at least one carbon-to-carbon double bond. Another term used to describe alkenes is olefins. Alkenes are more reactive than alkanes due to the presence of the double bond.
The document discusses the Diels-Alder reaction, which involves a diene reacting with a dienophile to form a six-membered ring. Key characteristics include versatility, stereoselectivity, and reversibility. The mechanism involves overlap of the HOMO of the diene and LUMO of the dienophile. The stereochemistry of products is governed by the cis principle and endo rule. Variations include retro Diels-Alder reactions and cycloadditions involving allyl cations/anions.
molecular rearrangement introduction which includes nucleophilic, electrophilic, and free radical rearrangement. and mechanism, applications of favorskki and benzil benzilic acid rearrangement.
Alkenes undergo addition reactions with halogens, hydrogen, and oxygen. When bromine is added to ethene, it produces dibromoethane by adding one bromine atom to each carbon in the double bond. Alkenes also react with hydrogen through hydrogenation, where hydrogen is added across the carbon-carbon double bond at 1500C with a nickel catalyst under pressure to produce the saturated alkane. When pentene undergoes hydrogenation, it forms pentane by adding hydrogen across the carbon-carbon double bond.
This document presents information about the Perkin reaction, which was discovered in the 19th century by English chemist William Henry Perkin. The Perkin reaction is an aldol condensation that converts an aromatic aldehyde and an acid anhydride to an alpha beta unsaturated cinnamic acid. It involves a four step mechanism - abstraction of alpha hydrogen from the acid anhydride, attack of the carbanion on the carbonyl carbon of benzaldehyde, an intramolecular acetyl shift, and loss of the acetate ion to form the unsaturated carboxylic acid product. The Perkin reaction is used to synthesize cinnamic acids, phytoestrogens, stilbenes, and resver
It includes reaction and it's mechanism and also applications. It contains stereochemistry of hydroboration . It also contains many exambles about hydroboration.
I hope You all like it. I hope It is very beneficial for you all. I really thought that you all get enough knowledge from this presentation. This presentation is about materials and their classifications. After you read this presentation you knowledge is not as before.
This document summarizes key information about alcohols and phenols. It discusses their structures, properties, synthesis methods, and reactions. Alcohols contain an OH group bonded to a saturated carbon. They are important solvents and intermediates. Phenol has diverse uses and gives its name to phenolic compounds. The document describes methods for synthesizing alcohols from alkenes, carbonyls, carboxylic acids, and Grignard reagents. It also outlines reactions of alcohols including dehydration, oxidation, conversion to halides, and incorporation into esters. Phenol is produced industrially from benzene sulfonic acid or chlorobenzene. Its hydroxyl group
This document discusses oxidation and various oxidizing agents. It begins by defining oxidation and reduction as the loss or gain of electrons, respectively. It then lists several common oxidizing agents including permanganates, dichromates, hypochlorous acid, chlorates, peroxides, and ozone. Specific details are provided about permanganates and how potassium permanganate can oxidize carbon atoms with pi-bonds, weak C-H bonds, and weak C-C bonds. Fuming sulfuric acid and chlorine dioxide are also discussed. The document concludes by covering liquid-phase oxidation using oxygen and examples of oxidations like acetaldehyde to acetic acid.
Alcohols contain an OH group bonded to a saturated carbon. Common alcohols include methanol, ethanol, and phenol. Alcohols can be synthesized through hydration of alkenes, reduction of carbonyl compounds, and using Grignard reagents. Alcohols undergo reactions such as dehydration, oxidation, and conversion to alkyl halides or tosylates. Phenol is produced through oxidation of cumene or hydrolysis of aryl diazonium salts. Phenol undergoes electrophilic aromatic substitution and can be carboxylated or acylated.
The document discusses the classification, nomenclature, preparation, properties and reactions of alcohols. Alcohols can be classified based on the number of hydroxyl groups and the carbon they are attached to. The IUPAC system names alcohols based on the parent chain and hydroxyl position. Alcohols can be prepared from alkyl halides, alkenes, carbonyl compounds and by reduction. They have higher boiling points than other organic compounds due to hydrogen bonding. Primary alcohols undergo SN2 reactions while tertiary undergo SN1. Oxidation of primary alcohols yields aldehydes and secondary yields ketones.
Alkenes are hydrocarbons that contain at least one carbon-carbon double bond. They have the general formula CnH2n. Common properties of alkenes include being unsaturated, less dense than water, and having lower melting and boiling points than alkanes. Alkenes undergo addition reactions where the double bond is broken and new single bonds are formed. They react with hydrogen, halogens, hydrogen halides, water, and acidified potassium manganate(VII) solution through addition reactions. Polymerization of alkenes forms polymers like polyethene. Alkenes burn with more soot than alkanes due to their higher carbon content.
This document provides information on the topic of homogeneous catalysis. It discusses several types of homogeneous catalysis including hydrogenation, hydroformylation, hydrocyanation, and Wilkinson catalysts. Hydrogenation involves adding hydrogen to organic compounds using molecular hydrogen and a catalyst. Hydroformylation adds a formyl group and hydrogen to an alkene. Hydrocyanation converts alkenes to nitriles. Wilkinson's catalyst is [RhCl(PPh3)3] and is widely used for hydrogenation reactions.
Aldehydes and ketones are organic compounds that contain a carbonyl functional group bonded to at least one hydrogen atom. Common aldehydes include formaldehyde and acetaldehyde. Ketones can be prepared through oxidation of secondary alcohols. Aldehydes and ketones undergo nucleophilic addition reactions that can be base-catalyzed or acid-catalyzed. They have many applications including use in resins, plastics, dyes, preservatives, solvents, drugs, and rubber products.
The document discusses chemical processes and various unit operations and processes. It provides examples of important industrial chemical reactions like sulfonation, halogenation, nitration, esterification, hydrogenation, oxidation, hydrolysis and polymerization. It explains the reaction mechanisms, conditions, and applications of these processes. The key reactions covered include electrophilic aromatic substitution, addition reactions, oxidation, hydrolysis, and step-growth polymerization. Industrial applications in production of chemicals, polymers, and other materials are also highlighted.
- Alcohols contain an -OH functional group which makes them polar and soluble in water. They can be classified as primary, secondary, or tertiary based on the number of carbon atoms bonded to the carbon attached to the OH group.
- Primary alcohols can be oxidized to aldehydes then carboxylic acids using oxidizing agents like acidified dichromate or manganate. Secondary alcohols oxidize to ketones. Tertiary alcohols do not oxidize.
- Burning alcohols releases energy with the amount increasing with the alcohol chain length due to more carbon dioxide produced. In limited oxygen, carbon monoxide is formed instead of carbon
The Vilsmeier-Haack reaction involves treating an electron-rich aromatic or heterocyclic system with a Vilsmeier reagent, which is formed from an amide like DMF and POCl3, to install a formyl group. The reaction proceeds through an iminium intermediate and takes place around 100°C in a solvent like DCM over 10-24 hours. It is useful for synthesizing aldehydes and ketones from electron-rich aromatic and heterocyclic substrates.
1) Crude oil is a naturally occurring mixture of hydrocarbons that can be separated into fractions of different molecular sizes and weights using fractional distillation.
2) Alkanes, alkenes, haloalkanes, alcohols, and carboxylic acids are important organic compound classes that undergo reactions like addition, substitution, oxidation, elimination, cracking, and polymerization.
3) These compound classes are involved in important processes like the production of fuels from crude oil, and the synthesis of materials like plastics through polymerization reactions.
Alkanes, Alkenes, Alkynes, Alkyl Halides, Alicyclic Hydrocarbons, Alcohols,
Ethers and Epoxides, Aldehydes and Ketones, Carboxylic Acids and their
Functional Derivatives
1. Electrophilic aromatic substitution is the characteristic reaction of benzene rings. A hydrogen atom is replaced by an electrophile through a two-step mechanism involving a resonance-stabilized cyclohexadienyl carbocation intermediate.
2. Substituents on benzene rings activate or deactivate the ring towards electrophilic aromatic substitution by influencing the stability of the carbocation intermediate. Electron-donating groups activate the ring while electron-withdrawing groups deactivate it.
3. The identity of existing substituents determines the orientation of new substituents, favoring either ortho/para or meta positions in electrophilic aromatic substitution.
1. The document discusses the chemical properties of hydrocarbons including alkanes, alkenes, and alkynes. It describes different types of chemical reactions such as combustion, addition, substitution, bromination, hydrogenation, and hydration.
2. Specific reactions are discussed including the combustion of hydrocarbons producing carbon dioxide and water. Addition reactions like bromination, hydrogenation, and hydration that involve adding atoms to alkenes and alkynes are also covered.
3. Examples are provided to illustrate combustion reactions, bromination of cyclohexene, hydrogenation of sunflower oil to produce solid fats, and the hydration of symmetrical and asymmetrical alkenes following Markovnik
This document provides a summary of key organic chemistry concepts in a flowchart format. It covers topics such as alkanes, alkenes, haloalkanes, alcohols, carboxylic acids, crude oil, alkynes, polymers, fractional distillation, and common reaction types including addition, substitution, oxidation, cracking, elimination, halogenation, and polymerization. The flowchart is intended to help with revision for Organic Chemistry 2.5 and provides brief descriptions and examples for each topic with hyperlinks to navigate between pages.
1) Alkyl halides are organic compounds containing one or more carbon-halogen bonds. They can be used as fire-resistant solvents, refrigerants, and in pharmaceuticals.
2) Alcohols contain an OH group bonded to a carbon atom. They exhibit hydrogen bonding which increases their boiling points relative to similar alkanes. Common alcohols include methanol, ethanol, and phenol.
3) Organic reactions can occur through addition, elimination, substitution, or rearrangement mechanisms. Reaction mechanisms are described through curved arrows to indicate the formation and breaking of covalent bonds. Polar reactions involve the attack of a nucleophile on an electrophile.
This document provides information about carbonyl compounds, specifically aldehydes and ketones. It discusses their IUPAC nomenclature, methods of preparation including oxidation of alcohols and oxidative cleavage of alkenes, and physical and chemical properties. The chemical reactions covered include nucleophilic addition, reduction, condensation, and oxidation reactions. Examples of important aldehydes and ketones are also mentioned along with their structures and uses.
Group #7 from COMSATS Institute of Information Technology presented on the chemistry of petrochemical processes related to ethylene. They discussed ethylene properties, major products including ethylene oxide and acetaldehyde. For ethylene oxide, they described its production through the controlled oxidation of ethylene over a silver catalyst. For acetaldehyde, they explained its production through both older ethanol oxidation methods and newer ethylene oxidation using a homogeneous Wacker catalyst at 130°C. They concluded that ethylene is a very important raw material for chemicals and polymers.
The document provides information about the production of ethylene dichloride (EDC) and vinyl chloride (VCM). It discusses two major routes for EDC production: direct chlorination of ethylene and oxychlorination of ethylene. For VCM production, the document focuses on the pyrolysis of EDC, where EDC is cracked at high temperatures to produce VCM and HCl. The key process steps involve vaporizing EDC, drying it, cracking it in a furnace, quenching the products, partially condensing and separating VCM from other components through distillation.
1. The document discusses various chemical conversion processes for biomass energy including hydrolysis, hydrogenation, and solvolysis. Hydrolysis involves using water to break chemical bonds, hydrogenation uses hydrogen gas and a catalyst to add hydrogen atoms to molecules, and solvolysis uses a solvent instead of water.
2. Specific examples of hydrolysis covered include salt hydrolysis, acid-base hydrolysis of esters and amides, and ATP hydrolysis which releases energy. Hydrogenation is commonly used to reduce double bonds in alkenes and methods include batch and continuous-flow systems. Solvolysis uses solvents like water or alcohols in substitution reactions.
Viruses are obligate intracellular parasites that infect all types of cells. They consist of nucleic acid surrounded by a protein coat and in some cases an envelope. Viruses hijack the host cell's machinery to replicate themselves and are then released to infect new host cells. There are many variations in the viral life cycle depending on whether the virus has DNA or RNA as its genome and whether it is enveloped. Viruses are classified based on their structure, composition and genetics.
Mycology is the branch of biology concerned with the study of fungi, including their genetic and biochemical properties, their taxonomy and their use to humans as a source for tinder, traditional medicine, food, and entheogens, as well as their dangers, such as toxicity or infection.
In the late 16th century several Dutch lens makers designed devices that magnified objects, but in 1609 Galileo Galilei perfected the first device known as a microscope. Dutch spectacle makers Zaccharias Janssen and Hans Lipperhey are noted as the first men to develop the concept of the compound microscope.
In the late 16th century several Dutch lens makers designed devices that magnified objects, but in 1609 Galileo Galilei perfected the first device known as a microscope. Dutch spectacle makers Zaccharias Janssen and Hans Lipperhey are noted as the first men to develop the concept of the compound microscope.
Microbial Spoilage include the contamination of Pharmaceutical products with the microbes which lead to spoilage of the product affecting Drug safety and quality, and is not intended for use. Shortly Microbial Spoilage is defined as deterioration of pharmaceutical products by the contaminant microbe.
In the late 16th century several Dutch lens makers designed devices that magnified objects, but in 1609 Galileo Galilei perfected the first device known as a microscope. Dutch spectacle makers Zaccharias Janssen and Hans Lipperhey are noted as the first men to develop the concept of the compound microscope.
Bacteria are a type of biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. Bacteria were among the first life forms to appear on Earth, and are present in most of its habitats
Microbiology is the study of organisms that are usually too small to be seen by the unaided eye; it employs techniques—such as sterilization and the use of culture media—that are required to isolate and grow these microorganisms.
Louis Pasteur in 1859 used swan-necked flasks to disprove the theory of spontaneous generation by showing that liquids in the flasks did not grow microbes due to being protected from dust and microbes in the air. Edward Jenner developed the first vaccine for smallpox in the late 1700s by inoculating people with material from cowpox lesions. Alexander Fleming discovered penicillin in 1928 after observing a mold that produced a chemical clearing surrounding bacteria on a culture plate.
Bacteria are microscopic, single-celled organisms that thrive in diverse environments. These organisms can live in soil, the ocean and inside the human gut. Humans' relationship with bacteria is complex. Sometimes bacteria lend us a helping hand, such as by curdling milk into yogurt or helping with our digestion
Bacteria are microscopic, single-celled organisms that thrive in diverse environments. These organisms can live in soil, the ocean and inside the human gut. Humans' relationship with bacteria is complex. Sometimes bacteria lend us a helping hand, such as by curdling milk into yogurt or helping with our digestion
Diuretics, also called water pills, are medications designed to increase the amount of water and salt expelled from the body as urine. There are three types of prescription diuretics. They're often prescribed to help treat high blood pressure, but they're used for other conditions as well.
The main site of diuretic action is well established for the different groups of diuretics: carbonic anhydrase inhibitors act on the proximal tubulus, loop diuretics on the diluting segment, thiazides on the cortical diluting segment/distal tubulus, and potassium-sparing agents on distal tubulus/collecting ducts.
Diuretics, also called water pills, are medications designed to increase the amount of water and salt expelled from the body as urine. There are three types of prescription diuretics. They’re often prescribed to help treat high blood pressure, but they’re used for other conditions as well.
Proton-pump inhibitors are a group of medications whose main action is a pronounced and long-lasting reduction of stomach acid production. Within the class of medications, there is no clear evidence that one agent works better than another. They are the most potent inhibitors of acid secretion available.
Synthesis of Naproxen, Ketoprofen, Ketorolac, Diclofenac and IbuprofenPharmacy Universe
This document summarizes the synthesis of several common nonsteroidal anti-inflammatory drugs (NSAIDs) including naproxen, ketoprofen, ketorolac, diclofenac, and ibuprofen. It outlines the key reaction steps for producing each compound, starting from various aromatic precursors and involving reactions such as acylation, alkylation, hydrolysis, bromination, reduction, chlorination, and hydrolysis.
The main site of diuretic action is well established for the different groups of diuretics: carbonic anhydrase inhibitors act on the proximal tubulus, loop diuretics on the diluting segment, thiazides on the cortical diluting segment/distal tubulus, and potassium-sparing agents on distal tubulus/collecting ducts.
In conclusion, the present study found that esomeprazole 40 mg daily may be more effective than either omeprazole 20 mg daily, pantoprazole 40 mg daily or lansoprazole 30 mg daily for the rapid relief of heartburn symptoms in patients with endoscopically proven reflux esophagitis.
Mechanisms of diuretic drugs. Diuretic drugs increase urine output by the kidney (i.e., promote diuresis). This is accomplished by altering how the kidney handles sodium. If the kidney excretes more sodium, then water excretion will also increase.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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Discover the benefits of homeopathic medicine for irregular periods with our guide on 5 common remedies. Learn how these natural treatments can help regulate menstrual cycles and improve overall menstrual health.
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The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...Université de Montréal
“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montreal
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)MuskanShingari
Statistics- Statistics is the science of collecting, organizing, presenting, analyzing and interpreting numerical data to assist in making more effective decisions.
A statistics is a measure which is used to estimate the population parameter
Parameters-It is used to describe the properties of an entire population.
Examples-Measures of central tendency Dispersion, Variance, Standard Deviation (SD), Absolute Error, Mean Absolute Error (MAE), Eigen Value
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
1. Alkenes: Reactions and
Synthesis
Md. Saiful Islam
Dept. of Pharmaceutical Sciences
North South University
Facebook Group: Pharmacy Universe
Md. Saiful Islam
Dept. of Pharmaceutical Sciences
North South University
Facebook Group: Pharmacy Universe
2. Diverse Reactions of Alkenes
• Alkenes react with many electrophiles to give useful products by
addition (often through special reagents)
2
3. Preparation of Alkenes: A Preview of
Elimination Reactions
• Alkenes are commonly made by
– elimination of HX from alkyl halide (dehydrohalogenation)
• Uses heat and KOH
– elimination of H-OH from an alcohol (dehydration)
• require strong acids (sulfuric acid, 50 ºC)
3
4. Addition of Halogens to Alkenes
• Bromine and chlorine add to alkenes to give 1,2-dihaldes, an
industrially important process
– F2 is too reactive and I2 does not add
• Cl2 reacts as Cl+
Cl-
– Br2 is similar
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5. Addition of Br2 to Cyclopentene
• Addition is exclusively trans
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6. Mechanism of Bromine Addition
• Br+
adds to an alkene producing a cyclic ion
• Bromonium ion, bromine shares charge with carbon
– Gives trans addition
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7. Bromonium Ion Mechanism
• Electrophilic addition of bromine to give a cation is followed by cyclization
to give a bromonium ion
• This bromonium ion is a reactive electrophile and bromide ion is a good
nucleophile
• Stereospecific anti addition
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8. Addition of Hypohalous Acids to
Alkenes: Halohydrin Formation
• This is formally the addition of HO-X to an alkene to give a 1,2-
halo alcohol, called a halohydrin
• The actual reagent is the dihalogen (Br2 or Cl2 in water in an
organic solvent)
8
9. Mechanism of Formation
of a Bromohydrin
• Br2 forms bromonium ion, then water adds
– Orientation toward stable C+
species
– Aromatic rings do not react
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10. Addition of Water to Alkenes:
Oxymercuration
• Hydration of an alkene is the addition of H-OH to to
give an alcohol
• Acid catalysts are used in high temperature industrial
processes: ethylene is converted to ethanol
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11. Oxymercuration Intermediates
• For laboratory-scale hydration of an alkene
• Use mercuric acetate in THF followed by sodium borohydride
• Markovnikov orientation
– via mercurinium ion
11
12. Reduction of Alkenes: Hydrogenation
• Addition of H-H across C=C
• Reduction in general is addition of H2or its equivalent, or a loss of O
from the molecule
• Requires Pt or Pd as powders on carbon and H2
• Hydrogen is first adsorbed on catalyst
• Reaction is heterogeneous (process is not in solution)
12
14. Permanganate Oxidation of Alkenes
• Oxidizing reagents other than ozone also cleave alkenes
• Potassium permanganate (KMnO4) can produce carboxylic acids
and carbon dioxide if H’s are present on C=C
14
15. Free Radical Polymerization: Initiation
• Initiation - a few radicals are generated by the reaction of a molecule
that readily forms radicals from a nonradical molecule
• A bond is broken homolytically
15
16. Polymerization: Propagation
• Radical from initiation adds to alkene to generate alkene radical
• This radical adds to another alkene, and so on many times
• Chain propagation ends when two radical chains combine
• Not controlled specifically but affected by reactivity and concentration
16
Termination
17. Other Polymers
• Other alkenes give other common polymers
• Radical stability: 3o
> 2o
> 1o
(just like with carbocations)
17