This case report describes a patient who experienced an acute loss of both cortical and subcortical posterior tibial nerve somatosensory evoked potentials during a lumbar laminectomy procedure. The evoked potentials were lost at 10:43 during the laminectomy but recovered fully 40 minutes later at 11:23 after decompression was complete. While monitoring lower extremity SSEPs during lumbar spine surgery is controversial due to multiple nerve roots contributing to the signals, this case demonstrates that significant neural compression can be detected using SSEPs during these types of procedures.