Pericardioscopy and pericardial biopsy can provide a minimally invasive method for diagnosing pericardial diseases. A study compared the diagnostic value of 3 approaches: fluoroscopic guidance with 3-6 samples, pericardioscopy guidance with 3-6 samples, and pericardioscopy with extensive sampling of 18-20 samples. Pericardioscopy provided excellent visualization and significantly improved sampling efficiency and diagnostic value compared to fluoroscopy. Extensive sampling via pericardioscopy further enhanced diagnostic accuracy by reducing false negatives from 58.3% to 6.7%.
OCT-Angiography is a dye-less method, unlike traditional Fluorescein Angiography and ICG. OCT-Angiography is three dimensional, which allows to scroll through depths and layers, showing superficial and deeper capillaries.
Presentation on large-scale e-Learning for Educators online professional development program and research with online training and courses by EdTech Leaders Online at EDC.
OCT-Angiography is a dye-less method, unlike traditional Fluorescein Angiography and ICG. OCT-Angiography is three dimensional, which allows to scroll through depths and layers, showing superficial and deeper capillaries.
Presentation on large-scale e-Learning for Educators online professional development program and research with online training and courses by EdTech Leaders Online at EDC.
ALISEO Treatment Of Iatrogenic Artery Pseudoaneurysm By Ultrasound Guided Fib...Salvatore Ronsivalle
Treatment Of Iatrogenic Artery Pseudoaneurysm By Ultrasound Guided Fibrin Glue Injection
Trattamento dello pseudoaneurisma iatrogeno mediante iniezione coguidata di colla di fibrina-
XXXIII° Congresso Nazionale della Società Italiana di Cardiologia Invasiva Porto Antico di Genova, Centro Congressi-3 ottobre 2012 Treatment of iatrogenic artery pseudoaneurysm by ultrasound guided fibrin glue injection: a single center experience Francesca Faresin; Francesca Franz; Marco Zennaro; Enrico Favaretto; Luigi Pedon; Salvatore Ronsivalle; Division of Vascular Surgery,Division of Cardiology, Cittadella Hospital, Padua, Italy-
(Angiologia-Chirurgia Vascolare-ULSS 15 Alta Padovana)
(Angiology- Vascular Surgery -ULSS 15 Alta Padovana)
Azoospermia is an challenging subject either on the diagnostic side or on the therapeutic issues. Types of testicular biopsy must be employed in selected patients as regard their background diagnosis e.g. obstructive, Klinefelter's,... etc.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...
192 pericardioscopy and pericardial biopsy
1. University Institute for Cardiovascular Diseases, Belgrade, YUUniversity Institute for Cardiovascular Diseases, Belgrade, YU
PERICARDIOSCOPY ANDPERICARDIOSCOPY AND
PERICARDIAL BIOPSYPERICARDIAL BIOPSY
- Belgrade experience -- Belgrade experience -
Prof. Petar M. Seferović, MD, PhD, FESC, FACC
2. Pericardioscopy and Pericardial BiopsyPericardioscopy and Pericardial Biopsy
HISTORICAL OVERVIEWHISTORICAL OVERVIEW
♦ Initiated byInitiated by Santos and FraterSantos and Frater in 1977in 1977
♦ Flexible pericardioscopy -Flexible pericardioscopy - KondosKondos et al.et al. JACCJACC
19861986
♦ Transcutaneous approach in local anesthesia -Transcutaneous approach in local anesthesia -
MaischMaisch et al.et al. Eur Heart JEur Heart J 19911991
♦ Until nowUntil now implemented inimplemented in 16 centers16 centers
♦ OnlyOnly Marburg, Maryland and BelgradeMarburg, Maryland and Belgrade seriesseries
are dealing with non-surgicalare dealing with non-surgical,, transcutaneoustranscutaneous
approach in local anesthesiaapproach in local anesthesia
3. ♦PE ofPE of unknown etiologyunknown etiology
♦PE in pts with knownPE in pts with known
malignancymalignancy
♦Verification ofVerification of perimyocarditisperimyocarditis
♦Verification ofVerification of tuberculoustuberculous
pericarditispericarditis
♦PBPPBP window verificationwindow verification
Pericardioscopy and Pericardial BiopsyPericardioscopy and Pericardial Biopsy
I N D I C A T I O N SI N D I C A T I O N S
4. Pericardioscopy and Pericardial BiopsyPericardioscopy and Pericardial Biopsy
AIM OF THE STUDYAIM OF THE STUDY
♦ TTo assess the feasibility and diagnostico assess the feasibility and diagnostic
value of three approaches to pericardialvalue of three approaches to pericardial
biopsy:biopsy:
1.1. FFluoroscopic controlluoroscopic control and standardand standard
samplingsampling
2.2. PPericardioscopyericardioscopy guidance with eitherguidance with either
standardstandard oror
3.3. EExtensive samplingxtensive sampling..
5. Pericardioscopy and Pericardial BiopsyPericardioscopy and Pericardial Biopsy
P A T I E N T SP A T I E N T S
PATIENTS N Males (%) Mean age
(yrs)
Evacuated PE
(ml)
Samples/pt
Group 1
(fluoroscopy)
12 66.7 46.7±12.2 775.0±171.2 3-6
Group 2
(pericardioscopy/
standard sampling)
22 50.0 50.8±10.4 769.5±185.7 4-6
Group 3
(pericardioscopy/
extensive sampling)
15 53.3 53.7±12.8 790.0±204.6 18-20
6. ♦ SubxiphoidSubxiphoid
pericardiocentesispericardiocentesis andand
drainage of PEdrainage of PE
♦ Instillation of 200 ml salineInstillation of 200 ml saline
♦ 7F7F introducer-sheath setintroducer-sheath set
♦ Position at thePosition at the upper leftupper left
laterallateral surface of thesurface of the
parietal pericardiumparietal pericardium
♦ OlympusOlympus FB-43ST forcepsFB-43ST forceps
(fenestrated, central needle)(fenestrated, central needle)
♦ 4-6 samples4-6 samples (mean 5.1)(mean 5.1)
Pericardial Biopsy Using FluoroscopyPericardial Biopsy Using Fluoroscopy
M E T H O DM E T H O D
N=12 pts (group 1)
7. ♦ SubxiphoidSubxiphoid pericardiocentesispericardiocentesis
and drainage of PEand drainage of PE
♦ LLocal anesthesiaocal anesthesia
♦ Olympus HYF-1Olympus HYF-1TT, 16F, 16F
flexible endoscopeflexible endoscope
♦ GGradual dilationradual dilation (9(9,, 12, 14F12, 14F))
up toup to 16.5F introducer-set16.5F introducer-set
♦ PericardialPericardial biopsy targeted bybiopsy targeted by
pericardioscopypericardioscopy ((OlympusOlympus
FB-43ST forceps )FB-43ST forceps )
Pericardioscopy and Pericardial BiopsyPericardioscopy and Pericardial Biopsy
M E T H O DM E T H O D
N=37 pts (groups 2 & 3)
8. Flexible percutaneous pericardioscopyFlexible percutaneous pericardioscopy
BELGRADE METHODOLOGYBELGRADE METHODOLOGY
MODIFICATIONSMODIFICATIONS
(Seferovic PM, et al. Herz 2000)(Seferovic PM, et al. Herz 2000)
♦ Olympus HYF-1T, 16FOlympus HYF-1T, 16F
flexible endoscope (flexible endoscope (biopsybiopsy
channel 2.2 mmchannel 2.2 mm))
♦ Active pericardial drainageActive pericardial drainage
♦ Intrapericardial instillationIntrapericardial instillation
of 100-300 ml of airof 100-300 ml of air
♦ AIMED BIOPSYAIMED BIOPSY
♦ EXTENSIVE SAMPLINGEXTENSIVE SAMPLING
(up to 20 samples/pt)(up to 20 samples/pt)
♦ Pericardioscopy after PBPPericardioscopy after PBP
13. 8.3 8.3
33.3
58.3
26.3
40.9
36.4
36.440
53.3 53.3
6.7
New Dg. Etiology Clin.Dg.confirmed No useful information
0
20
40
60
80
100
%
Fluoroscopic biopsy (3-6 samples)
Pericardioscopy (3-6 samples)
Pericardioscopy (18-20 samples)
* *
* *
DIAGNOSTIC VALUE OFDIAGNOSTIC VALUE OF
PERICARDIOSCOPYPERICARDIOSCOPY ANDAND
PERICARDIAL BIOPSYPERICARDIAL BIOPSY
14. ♦ Excellent visualizationExcellent visualization but nonspecificbut nonspecific
macroscopic findingsmacroscopic findings..
♦ Pericardioscopic guidancePericardioscopic guidance enhancedenhanced
pericardial sampling efficiency.pericardial sampling efficiency.
♦ TheThe diagnostic value of pericardial biopsydiagnostic value of pericardial biopsy
was significantly improved by extensivewas significantly improved by extensive
samplingsampling made possible by pericardioscopy.made possible by pericardioscopy.
Pericardioscopy and Pericardial BiopsyPericardioscopy and Pericardial Biopsy
CONCLUSIONSCONCLUSIONS