Peritoneal dialysis by Dr. Basil TumainiBasil Tumaini
Peritoneal dialysis by Dr. Basil Tumaini, prepared for nephrology lecture during the residency in Internal medicine at Muhimbili University of Health and Allied Sciences
The evaluation of peritoneal membrane is very important for selection of appropriate modality of peritoneal dialysis. Peritoneal membrane is a living membrane so periodic evaluation is important.
Peritoneal dialysis by Dr. Basil TumainiBasil Tumaini
Peritoneal dialysis by Dr. Basil Tumaini, prepared for nephrology lecture during the residency in Internal medicine at Muhimbili University of Health and Allied Sciences
The evaluation of peritoneal membrane is very important for selection of appropriate modality of peritoneal dialysis. Peritoneal membrane is a living membrane so periodic evaluation is important.
خلاصه:
دیالیز صفاقی یکی از روش های درمانی جایگزین در کودکان با نارسایی مزمن و شدید کلیه می باشد . روش ساده ای است که بدون وابستگی به مرکز میتوان در منزل انجام داد و به فعالیتهای معمول ادامه داد. در این روش کاتتر دیالیز که تنکوف می باشد و معمولا انتهای پیچ خورده ای دارد و گردن خروجی ان به صورت خمیده می باشد به روش جراحی یا در کنار تخت بیمار کاتتر وارد شکم و به طرف پشت مثانه هدایت می شود. در کودکان به منظور جلوگیری ازانسداد کاتتر ، امنتکتومی صورت میگیرد. معمولا دوهفته بعد از کاتتر گذاری می توان دیالیز را شروع کرد. محلول دیالیز صفاقی خاصیت اسموتیک بالا دارد و عمدتا دارای قند بالا می باشد . قند موجود در مایع دیالیز کمک می کند تا آب و املاح براساس خاصیت اسموتیک از خون به حفره صفاق جابجا شوند، براساس خاصیت انتشار اوره و کراتینین ، فسفر و پتاسیم جابجا میشوند تا به تعادل برسند. حجم مایع دیالیز معمولا 1100 سی سی به ازای هر متر مربع در کودکان بالای یکسا ل و 600 سی سی به ازای هر متر مربع بدن در کودکان زیر یکسال می باشد. بهتر است دفعات تجویز مایع دیالیز با اندازه گیری تست تعادل پریتوئن صورت گیرد. به منظور جلوگیری از بروز فتق ویا نشت بهتر است حجم مایع تجویز شده با اندازه گیری فشارداخل شکم کنترل شود. وفشارداخل شکم کمتراز 18 سانتی متر آب نگهداشته شود. عوارض دیالیز صفاقی به عوارض عفونی ( پریتونیت ، عفونت محل خروج کاتتر و یا تونل) و حوادث غیر عفونی شامل بروز فتق ، نشت مایع دیالیز ، تجمع مایع د رفضای پریتونئال ، جابجایی کاتتر دیالیز صفاقی ، چسبندگی وانسداد ونهایتا فیبروز اسکلروزه پریتوئن می باشد. درکودکان توجه به دریافت مناسب کالری متناسب با سن برای رشد قدی و وزنی ضروری است.
Management of Acute Pancreatitis By Dr. Dhaval Mangukiya
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Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
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The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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13. Why to start with PD ? 1. better maintenance of residual renal function
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15. Ramesh Khanna & Karl D. Nolph 80% of patients have no contra-indication to any of the dialysis methods and may choose according to their life style between HD a PD Absolute contra-indications of PD: 1.peritoneal fibrosis and adhesions following intraabdominal operations 2.inflammatory gut diseases Indication / Contraindications of PD
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18. NIPD – night intermitent peritoneal dialysis (cycler)
21. PET (peritoneal equilibration test) 2 CAPD, 5 exchanges daily + 1 exchange at night Good Slow Slow CAPD or APD OK OK Average Frequent exchanges, short dwells – APD Poor Fast High Best type of PD Water removal Waste removal Transporter
33. Morphologic changes of peritoneum due to PD (1) Obr.1-before starting PD, norm. peritoneum (omentum)
34. Morphologic changes of peritoneum due to PD (2) Obr.2-after 3 years of PD, submesotelial fibrosis and neo-angiogenesis (enlargement of vascular surface of peritoneum)
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38. Physioneal Infusion pain Peritonitis Glycemic control Appetite Patient acceptance No UF Clinical advantages of new dialysis solutions Extraneal Glucose load Glycemic control UF, control of fluid status Dyslipidemia Quality of life Time on PD Pecoits-Filho, et al. Kidney Int . 2003;64(suppl 88):S100-S104. Vardhan, et al. Kidney Int. 2003;64(suppl 88):S114-S123. Nutrineal Glucose load Glycemic control Protein intake, nutritional status
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Editor's Notes
Název Autor Pracoviště Datum zpracování přednášky
Category: Peritoneal Membrane Preservation This slide shows the beneficial effects of the newer PD solutions containing alternate buffers and osmotic agents. All three solutions reduce levels of GDPs and AGEs. With Physioneal, it is because glucose is sterilized at a very low pH. With Extraneal and Nutrineal, it is because there is no glucose in either solution. Additional benefits of Physioneal : Physiologic pH and pCO 2 , reduced lactate levels. Additional benefit of Extraneal: Same osmolarity as plasma. As a result of its unique properties, each solution has been shown to improve membrane and peritoneal immune cell function. Skoufos L, Topley N, Cooker L, et al. The in vitro biocompatibility performance of a 25 mmol/L bicarbonate/10 mmol/L lactate-buffered peritoneal dialysis fluid. Kidney Int . 2003;64(suppl 88):S94-S99. Vardhan A, Zweers MM, Gokal R, Krediet RT. A solutions portfolio approach in peritoneal dialysis. Kidney Int . 2003;64(suppl 88):S114-S123.
Category: Peritoneal Membrane Preservation This slide shows the beneficial effects of the newer PD solutions containing alternate buffers and osmotic agents. All three solutions reduce levels of GDPs and AGEs. With Physioneal, it is because glucose is sterilized at a very low pH. With Extraneal and Nutrineal, it is because there is no glucose in either solution. Additional benefits of Physioneal : Physiologic pH and pCO 2 , reduced lactate levels. Additional benefit of Extraneal: Same osmolarity as plasma. As a result of its unique properties, each solution has been shown to improve membrane and peritoneal immune cell function. Skoufos L, Topley N, Cooker L, et al. The in vitro biocompatibility performance of a 25 mmol/L bicarbonate/10 mmol/L lactate-buffered peritoneal dialysis fluid. Kidney Int . 2003;64(suppl 88):S94-S99. Vardhan A, Zweers MM, Gokal R, Krediet RT. A solutions portfolio approach in peritoneal dialysis. Kidney Int . 2003;64(suppl 88):S114-S123.
This slide summarizes the clinical benefits of Physioneal, Extraneal, and Nutrineal as described in the articles by Pecoits-Filho, et al (S100) and Vardhan, et al (S114). Pecoits-Filho R, Tranaeus A, Lindholm B. Clinical trial experiences with Physioneal™. Kidney Int . 2003;64(suppl 88):S100-S104. Vardhan A, Zweers MM, Gokal R, Krediet RT. A solutions portfolio approach in peritoneal dialysis. Kidney Int . 2003;64(suppl 88):S114-S123.
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