This document summarizes key properties and challenges of microbial biofilms. It discusses how biofilms form complex structures that protect microbes and enable gene transfer. Antibiotics have difficulty penetrating biofilms and the local environment inside biofilms can alter antibiotic effectiveness. Biofilms also harbor subpopulations of highly resistant cells. The document outlines how biofilms contribute to various chronic infections and problems in fields like engineering. It reviews current and potential future strategies for disrupting or preventing biofilms.