Cells & Cell Organelles
                Doing Life’s Work




AP Biology                             2009-2010
bacteria
   Types of cells                  cells
                                         Prokaryote
                                         - no organelles




                       Eukaryotes
                       - organelles


        animal cells                  plant cells
Regents Biology
Cell size comparison

                  Animal cell                    most bacteria
                                Bacterial cell     1-10 microns
                                                 eukaryotic cells
                                                   10-100 microns




                           micron = micrometer = 1/1,000,000 meter
Regents Biology            diameter of human hair = ~20 microns
Why study cells?
    Cells → Tissues → Organs → Bodies
         bodies are made up of cells
         cells do all the work of life!




Regents Biology
The Work of Life
    What jobs do cells have to do for an organism to live…
          “breathe”
            gas exchange: O2 in vs. CO2 out
          eat
            take in & digest food
          make energy
            ATP                         ATP
          build molecules
            proteins, carbohydrates, fats, nucleic acids
          remove wastes
          control internal conditions
            homeostasis
          respond to external environment
          build more cells
            growth, repair, reproduction & development
Regents Biology
The Jobs of Cells
    Cells have 3 main jobs
           make energy
             need energy for all activities
 ATP                                                Our organelles
             need to clean up waste produced        do all these
                                                        jobs!
              while making energy
           make proteins
             proteins do all the work in a cell,
              so we need lots of them
           make more cells
             for growth
             to replace damaged or diseased cells
Regents Biology
Organelles
     Organelles do the work of cells
           each structure has a job to do
             keeps the cell alive; keeps you alive




 They’re like
 mini-organs!




Regents Biology
                                                      Model Animal Cell
1. Cells need power!
     Making energy
             to fuel daily life & growth, the cell must…
               take in food & digest it
               take in oxygen (O2)
  ATP          make ATP
               remove waste
             organelles that do this work…
               cell membrane
               lysosomes
               vacuoles & vesicles
               mitochondria
Regents Biology
phosphate
   Cell membrane                                  “head”

 Function
     separates cell from outside
     controls what enters or leaves cell        lipid “tail”
         O2, CO2, food, H2O, nutrients, waste
       recognizes signals from other cells
         allows communication between cells
 Structure
       double layer of fat
         phospholipid bilayer
       receptor molecules
         proteins that
          receive signals
Regents Biology
cytoplasm
jelly-like material holding
 organelles in place




cell membrane
cell boundary
controls movement
 of materials in & out
recognizes signals
 Regents Biology
Vacuoles & vesicles
                                    Function
                                      moving material
                                       around cell
                                      storage


small food
                                    Structure
  particle
                                        membrane sac
                                          vacuole filled w/
                                         digestive enzymes
        vesicle


               vesicle filled w/
             digested nutrients
Regents Biology
Food & water storage
                                food vacuole
  plant cells
central vacuole




                                 animal cells



                  contractile
Regents Biology    vacuole
cytoplasm
jelly-like material holding
 organelles in place

vacuole & vesicles
transport inside cells
storage




cell membrane
cell boundary
controls movement
 of materials in & out
recognizes signals
 Regents Biology
 Function
   Lysosomes                             digest food
                                           used to make energy
                                         clean up & recycle
                                           digest broken
                                            organelles
                                     Structure
                                         membrane sac of
                        lysosomes         digestive enzymes

                                           digesting broken
                                           organelles
small food        vacuole
  particle

                  digesting food

Regents Biology
A Job for Lysosomes
6 weeks




                         15 weeks




Regents Biology
cytoplasm
jelly-like material holding   lysosome
 organelles in place           food digestion
                               garbage disposal &
vacuole & vesicles              recycling
transport inside cells
storage




cell membrane
cell boundary
controls movement
                                         o
                                         f
 Regents Biology
                                         m
Mitochondria
 Function
      make ATP energy from cellular respiration
        sugar + O2 → ATP
        fuels the work of life
 Structure                                 ATP
      double membrane



 in both animal &
 plant cells
Regents Biology
cytoplasm
jelly-like material holding   lysosome
 organelles in place           food digestion
                               garbage disposal &
vacuole & vesicles              recycling
transport inside cells
storage




mitochondria
make ATP energy
 from sugar + O2
cell membrane
cell boundary
controls movement
 of materials in & out
recognizes signals
 Regents Biology
Plants make energy two ways!
 Mitochondria
        make energy from sugar + O2
                                                       ATP
          cellular respiration
          sugar + O2 → ATP
 Chloroplasts
        make energy + sugar from sunlight
          photosynthesis
                                           sugar
          sunlight + CO2 → ATP & sugar
             ATP = active energy
             sugar = stored energy
                                                     ATP
                     build leaves & roots & fruit
                      out of the sugars
Regents Biology
Mitochondria are in both cells!!
      animal cells         plant cells




                  mitochondria
                                 chloroplast
Regents Biology
cytoplasm
jelly-like material
 around organelles                                central vacuole
                                                  storage: food,
                                                   water or waste

mitochondria                                             cell wall
make ATP in                                             support
 cellular respiration

cell membrane                                chloroplast
cell boundary                               make ATP & sugars in
controls movement                            photosynthesis
 of materials in & out   lysosome
recognizes signals
Regents Biology          digestion & clean up
2. Cells need workers = proteins!
     Making proteins
             to run daily life & growth, the cell must…
               read genes (DNA)
               build proteins
                  structural proteins (muscle fibers, hair, skin, claws)
                  enzymes (speed up chemical reactions)
                  signals (hormones) & receptors
             organelles that do this work…
                 nucleus
                 ribosomes
                 endoplasmic reticulum (ER)
                 Golgi apparatus
Regents Biology
Proteins do all the work!
       one of the major job of cells is to make proteins,
                          because…

                   proteins do all the work!
                                                structural
                                                enzymes
                                                signals
                                                receptors

     DNA                  proteins              cells

Regents Biology
Nucleus
    Function
        control center of cell
        protects DNA

            instructions for building proteins
    Structure
        nuclear membrane
        nucleolus

            ribosome factory
          chromosomes
            DNA
Regents Biology
cytoplasm
jelly-like material holding   lysosome              nucleolus
 organelles in place           food digestion       produces
                               garbage disposal &    ribosomes
vacuole & vesicles              recycling            nucleus
transport inside cells                              protects DNA
storage                                             controls cell

                                                     chromosomes
                                                     DNA



mitochondria
make ATP energy
 from sugar + O2
cell membrane
cell boundary
controls movement
 of materials in & out
recognizes signals
 Regents Biology
Ribosomes
      Function
             protein factories
             read instructions to build proteins from DNA
      Structure
             some free in cytoplasm
             some attached to ER
                                       Ribosomes on ER




Regents Biology
cytoplasm
jelly-like material holding   lysosome               nucleolus
 organelles in place           food digestion        produces
                               garbage disposal &     ribosomes
vacuole & vesicles              recycling
                                                      nucleus
transport inside cells                               protects DNA
storage                                              controls cell




                                                     ribosomes
mitochondria                                         build proteins
make ATP energy
 from sugar + O2
cell membrane
cell boundary
controls movement
 of materials in & out
recognizes signals
 Regents Biology
Endoplasmic Reticulum
    Function
           works on proteins
             helps complete the
              proteins after ribosome
              builds them
           makes membranes
     Structure
           rough ER
             ribosomes attached
             works on proteins
           smooth ER
             makes membranes
Regents Biology
cytoplasm
jelly-like material holding      lysosome
 organelles in place              food digestion
                                  garbage disposal &
vacuole & vesicles                 recycling
                                                         nucleus
transport inside cells                                  protects DNA
storage                                                 controls cell




                                                        ribosomes
mitochondria                                            builds proteins
make ATP energy
 from sugar + O2
cell membrane
cell boundary                 ER
controls movement             works on proteins
 of materials in & out         makes membranes
recognizes signals
 Regents Biology
Golgi Apparatus
     Function
             finishes, sorts, labels & ships proteins
               like UPS headquarters
                  shipping & receiving department
             ships proteins in vesicles
                                                          vesicles
               “UPS trucks”                         carrying proteins
      Structure
             membrane sacs




Regents Biology                                transport vesicles
cytoplasm
jelly-like material holding       lysosome
 organelles in place               food digestion
                                   garbage disposal &
vacuole & vesicles                  recycling
                                                            nucleus
transport inside cells                                     protects DNA
storage                                                    controls cell




                                                           ribosomes
mitochondria                                               builds proteins
make ATP energy
 from sugar + O2                                        Golgi apparatus
cell membrane                                           finishes, packages
cell boundary                 ER                        & ships proteins
controls movement             helps finish proteins
 of materials in & out         makes membranes
recognizes signals
 Regents Biology
nucleus             endoplasmic
                          reticulum
                                                  protein
    DNA                                          on its way!              TO:




             RNA                       vesicle                      TO:




                                                              TO:

                                                              vesicle
        ribosomes

                                                        TO:


                   protein                              finished
                                                         protein

                                  Golgi
                                apparatus
   Making Proteins
Regents Biology
nucleolus
                         make ribosomes       endoplasmic reticulum
nucleus                                        processes proteins
control cell                                  makes membranes
protects DNA
                                                       ribosomes
cytoplasm                                              make proteins
jelly-like material
 around organelles
                                                     central vacuole
Golgi apparatus
                                                     storage: food,
finish & ship
 proteins
mitochondria                                                cell wall
make ATP in                                                support
 cellular respiration

cell membrane                                  chloroplast
cell boundary                                 make ATP & sugars in
controls movement                              photosynthesis
 of materials in & out     lysosome
recognizes signals
Regents Biology            digestion & clean up
3. Cells need to make more cells!
   Making more cells
          to replace, repair & grow,
           the cell must…
            copy their DNA
            make extra organelles
            divide the new DNA & new
             organelles between 2 new
             “daughter” cells
          organelles that do this
           work…
            nucleus
            centrioles
Regents Biology
Centrioles
    Function
           help coordinate cell division
             only in animal cells
     Structure
           one pair in each cell




Regents Biology
cytoplasm
jelly-like material holding       lysosome
 organelles in place               food digestion
                                   garbage disposal &
vacuole & vesicles                  recycling
                                                            nucleus
transport inside cells                                     protects DNA
storage                                                    controls cell

centrioles
cell division

                                                           ribosomes
mitochondria                                               builds proteins
make ATP energy
 from sugar + O2                                        Golgi apparatus
cell membrane                                           finishes, packages
cell boundary                 ER                        & ships proteins
controls movement             helps finish proteins
 of materials in & out         makes membranes
recognizes signals
 Regents Biology
Cell Summary
    Cells have 3 main jobs
           make energy
             need food + O2
             cellular respiration & photosynthesis
             need to remove wastes               Our organelles
                                                   do all those
           make proteins                             jobs!
             need instructions from DNA
             need to chain together amino acids & “finish”
              & “ship” the protein
           make more cells
             need to copy DNA & divide it up to daughter cells
Regents Biology
That’s my
             cellular story…
             Any Questions?
AP Biology                     2009-2010

01 cellorganelles2009regents

  • 1.
    Cells & CellOrganelles Doing Life’s Work AP Biology 2009-2010
  • 2.
    bacteria Types of cells cells Prokaryote - no organelles Eukaryotes - organelles animal cells plant cells Regents Biology
  • 3.
    Cell size comparison Animal cell most bacteria Bacterial cell  1-10 microns eukaryotic cells  10-100 microns  micron = micrometer = 1/1,000,000 meter Regents Biology  diameter of human hair = ~20 microns
  • 4.
    Why study cells?  Cells → Tissues → Organs → Bodies  bodies are made up of cells  cells do all the work of life! Regents Biology
  • 5.
    The Work ofLife  What jobs do cells have to do for an organism to live…  “breathe”  gas exchange: O2 in vs. CO2 out  eat  take in & digest food  make energy  ATP ATP  build molecules  proteins, carbohydrates, fats, nucleic acids  remove wastes  control internal conditions  homeostasis  respond to external environment  build more cells  growth, repair, reproduction & development Regents Biology
  • 6.
    The Jobs ofCells  Cells have 3 main jobs  make energy  need energy for all activities ATP Our organelles  need to clean up waste produced do all these jobs! while making energy  make proteins  proteins do all the work in a cell, so we need lots of them  make more cells  for growth  to replace damaged or diseased cells Regents Biology
  • 7.
    Organelles  Organelles do the work of cells  each structure has a job to do  keeps the cell alive; keeps you alive They’re like mini-organs! Regents Biology Model Animal Cell
  • 8.
    1. Cells needpower!  Making energy  to fuel daily life & growth, the cell must…  take in food & digest it  take in oxygen (O2) ATP  make ATP  remove waste  organelles that do this work…  cell membrane  lysosomes  vacuoles & vesicles  mitochondria Regents Biology
  • 9.
    phosphate Cell membrane “head”  Function  separates cell from outside  controls what enters or leaves cell lipid “tail”  O2, CO2, food, H2O, nutrients, waste  recognizes signals from other cells  allows communication between cells  Structure  double layer of fat  phospholipid bilayer  receptor molecules  proteins that receive signals Regents Biology
  • 10.
    cytoplasm jelly-like material holding organelles in place cell membrane cell boundary controls movement of materials in & out recognizes signals Regents Biology
  • 11.
    Vacuoles & vesicles  Function  moving material around cell  storage small food  Structure particle  membrane sac vacuole filled w/ digestive enzymes vesicle vesicle filled w/ digested nutrients Regents Biology
  • 12.
    Food & waterstorage food vacuole plant cells central vacuole animal cells contractile Regents Biology vacuole
  • 13.
    cytoplasm jelly-like material holding organelles in place vacuole & vesicles transport inside cells storage cell membrane cell boundary controls movement of materials in & out recognizes signals Regents Biology
  • 14.
     Function Lysosomes  digest food  used to make energy  clean up & recycle  digest broken organelles  Structure  membrane sac of lysosomes digestive enzymes digesting broken organelles small food vacuole particle digesting food Regents Biology
  • 15.
    A Job forLysosomes 6 weeks 15 weeks Regents Biology
  • 16.
    cytoplasm jelly-like material holding lysosome organelles in place food digestion garbage disposal & vacuole & vesicles recycling transport inside cells storage cell membrane cell boundary controls movement o f Regents Biology m
  • 17.
    Mitochondria  Function  make ATP energy from cellular respiration  sugar + O2 → ATP  fuels the work of life  Structure ATP  double membrane in both animal & plant cells Regents Biology
  • 18.
    cytoplasm jelly-like material holding lysosome organelles in place food digestion garbage disposal & vacuole & vesicles recycling transport inside cells storage mitochondria make ATP energy from sugar + O2 cell membrane cell boundary controls movement of materials in & out recognizes signals Regents Biology
  • 19.
    Plants make energytwo ways!  Mitochondria  make energy from sugar + O2 ATP  cellular respiration  sugar + O2 → ATP  Chloroplasts  make energy + sugar from sunlight  photosynthesis sugar  sunlight + CO2 → ATP & sugar  ATP = active energy  sugar = stored energy ATP  build leaves & roots & fruit out of the sugars Regents Biology
  • 20.
    Mitochondria are inboth cells!! animal cells plant cells mitochondria chloroplast Regents Biology
  • 21.
    cytoplasm jelly-like material aroundorganelles central vacuole storage: food, water or waste mitochondria cell wall make ATP in support cellular respiration cell membrane chloroplast cell boundary make ATP & sugars in controls movement photosynthesis of materials in & out lysosome recognizes signals Regents Biology digestion & clean up
  • 22.
    2. Cells needworkers = proteins!  Making proteins  to run daily life & growth, the cell must…  read genes (DNA)  build proteins  structural proteins (muscle fibers, hair, skin, claws)  enzymes (speed up chemical reactions)  signals (hormones) & receptors  organelles that do this work…  nucleus  ribosomes  endoplasmic reticulum (ER)  Golgi apparatus Regents Biology
  • 23.
    Proteins do allthe work! one of the major job of cells is to make proteins, because… proteins do all the work! structural enzymes signals receptors DNA proteins cells Regents Biology
  • 24.
    Nucleus  Function  control center of cell  protects DNA  instructions for building proteins  Structure  nuclear membrane  nucleolus  ribosome factory  chromosomes  DNA Regents Biology
  • 25.
    cytoplasm jelly-like material holding lysosome nucleolus organelles in place food digestion produces garbage disposal & ribosomes vacuole & vesicles recycling nucleus transport inside cells protects DNA storage controls cell chromosomes DNA mitochondria make ATP energy from sugar + O2 cell membrane cell boundary controls movement of materials in & out recognizes signals Regents Biology
  • 26.
    Ribosomes  Function  protein factories  read instructions to build proteins from DNA  Structure  some free in cytoplasm  some attached to ER Ribosomes on ER Regents Biology
  • 27.
    cytoplasm jelly-like material holding lysosome nucleolus organelles in place food digestion produces garbage disposal & ribosomes vacuole & vesicles recycling nucleus transport inside cells protects DNA storage controls cell ribosomes mitochondria build proteins make ATP energy from sugar + O2 cell membrane cell boundary controls movement of materials in & out recognizes signals Regents Biology
  • 28.
    Endoplasmic Reticulum  Function  works on proteins  helps complete the proteins after ribosome builds them  makes membranes  Structure  rough ER  ribosomes attached  works on proteins  smooth ER  makes membranes Regents Biology
  • 29.
    cytoplasm jelly-like material holding lysosome organelles in place food digestion garbage disposal & vacuole & vesicles recycling nucleus transport inside cells protects DNA storage controls cell ribosomes mitochondria builds proteins make ATP energy from sugar + O2 cell membrane cell boundary ER controls movement works on proteins of materials in & out makes membranes recognizes signals Regents Biology
  • 30.
    Golgi Apparatus  Function  finishes, sorts, labels & ships proteins  like UPS headquarters  shipping & receiving department  ships proteins in vesicles vesicles  “UPS trucks” carrying proteins  Structure  membrane sacs Regents Biology transport vesicles
  • 31.
    cytoplasm jelly-like material holding lysosome organelles in place food digestion garbage disposal & vacuole & vesicles recycling nucleus transport inside cells protects DNA storage controls cell ribosomes mitochondria builds proteins make ATP energy from sugar + O2 Golgi apparatus cell membrane finishes, packages cell boundary ER & ships proteins controls movement helps finish proteins of materials in & out makes membranes recognizes signals Regents Biology
  • 32.
    nucleus endoplasmic reticulum protein DNA on its way! TO: RNA vesicle TO: TO: vesicle ribosomes TO: protein finished protein Golgi apparatus Making Proteins Regents Biology
  • 33.
    nucleolus make ribosomes endoplasmic reticulum nucleus processes proteins control cell makes membranes protects DNA ribosomes cytoplasm make proteins jelly-like material around organelles central vacuole Golgi apparatus storage: food, finish & ship proteins mitochondria cell wall make ATP in support cellular respiration cell membrane chloroplast cell boundary make ATP & sugars in controls movement photosynthesis of materials in & out lysosome recognizes signals Regents Biology digestion & clean up
  • 34.
    3. Cells needto make more cells!  Making more cells  to replace, repair & grow, the cell must…  copy their DNA  make extra organelles  divide the new DNA & new organelles between 2 new “daughter” cells  organelles that do this work…  nucleus  centrioles Regents Biology
  • 35.
    Centrioles  Function  help coordinate cell division  only in animal cells  Structure  one pair in each cell Regents Biology
  • 36.
    cytoplasm jelly-like material holding lysosome organelles in place food digestion garbage disposal & vacuole & vesicles recycling nucleus transport inside cells protects DNA storage controls cell centrioles cell division ribosomes mitochondria builds proteins make ATP energy from sugar + O2 Golgi apparatus cell membrane finishes, packages cell boundary ER & ships proteins controls movement helps finish proteins of materials in & out makes membranes recognizes signals Regents Biology
  • 37.
    Cell Summary  Cells have 3 main jobs  make energy  need food + O2  cellular respiration & photosynthesis  need to remove wastes Our organelles do all those  make proteins jobs!  need instructions from DNA  need to chain together amino acids & “finish” & “ship” the protein  make more cells  need to copy DNA & divide it up to daughter cells Regents Biology
  • 38.
    That’s my cellular story… Any Questions? AP Biology 2009-2010