Inorganic chemistry Sem 1 Pharmacy

1. DEPARTMENT OF PHARMACY
NAGPUR COLLEGE OF PHARMACY,
WANADONGRI ,NAGPUR

2. Author: Dr Sanjana N Gaikwad
Department :Pharmaceutics
Subject: Inorganic Chemistry
Nagpur college of Pharmacy, Wanadongri ,Nagpur
EMETICS

3. • To understand the medicinal and pharmaceutical
importance
• To know about pharmaceutical compounds and
their uses as emetics
PURPOSE

4. 1. What are Emetics
2. Classification
3. Uses
LEARNING OBJECTIVES

5. EMETICS
• Emetics are derived from word emesis which mean
vomiting
• Vomiting is forceful expulsion of contents present in
stomach through mouth sometimes through nose
• Emetics are the drugs which give rise to forced emesis
by which the contents of the stomach get expelled
through the oral cavity.
• They are very important in cases ofPoisoning.

7. • Added to cough preparation to lower the dose
• Most salts in higher doses act as emetics
• Used as mechanical antidotes
• Not to be given in state of shock ,
unconsciousness and depression
• Important in case of poisoning or other harmful
substances

9. The emetics can be acting by 2 types:
1. Reflux producing irritation : by local irritation of gastric mucosa.
e.g. Copper sulphate, sodium chloride, Zinc sulphate
2. Centrally acting emetics: directly on the Chemoreceptor Trigger
Zone (CTZ) in the floor of IV th ventricle in medulla
e.g. Apomorphine & Morphine
MECHANISM OF ACTION

11. 1.Vomiting is primarily considered to be a respiratory function, its
ultimate result would cause the evacuation of the stomach thus
emetics produces a reflux aaction by which
2.Toxic substances gets expelled in case of poisoning.
3.Emetics are sometimes added to cough preparations in low doses
to stimulate flow of respiratory tract secretions.
4.Side effects: Headache, constipation, and dizziness are the most
commonly reported side effects associated with its use
USES

12. • Emetics are substances which are primarily used for
emesis in poisoning which act by different mode of
action
• Emesis and related behaviors, should be addressed not
only by researchers of emesis, but by disciplines
researching energy balance and ingestive behavior.
• The drugs which give rise to forced regurgitation (emesis)
by which the contents of the stomach get expelled
through the oral cavity.
• They are very important in cases of poisoning.
SUMMARY

13. 1. G.R Chatwal:Pharmaceutical Chemistry Inorganic,
himalaya publishing house Vol 1
2. P. Gundu Rao, Inorganic Pharmaceutical
Chemistry, 3rd Edition
3. M.L Schroff, Inorganic Pharmaceutical Chemistry
BIBLIOGRAPHY

14. 1. What are emetics ? Classify them?
2. Explain the mechanism of action of emetic.
QUESTIONS?