This document summarizes information about pneumatic tube systems (PTS) used for transporting laboratory samples and medical supplies within hospitals. It provides details about the components, operation, and applications of PTS. It also reviews several studies that have evaluated the impact of PTS transportation on various laboratory tests and sample quality, finding that PTS transportation does not significantly affect most tests as long as proper containers and protocols are used. The document concludes that PTS can improve turnaround times and reduce costs while being a generally safe method for intra-hospital transportation.