Urinary System Of Goat
 Presented To:
 Sir Zeeshan Akbar Sb.
 Presented By:
 14-Arid-2030
 14-Arid-2029
 14-Arid-2028
 14-Arid-2036

 DVM 1st (Evening)
 Group (A)
Homeostasis
 The urinary system maintains homeostasis in
several ways:
 Removal of urea (nitrogenous waste) from the
bloodstream.
 Control of water and salt balance in the bloodstream.
 Involved in blood pressure regulation.
Renin
 Renin is an enzyme released by the kidneys in
response to a drop in blood pressure.
 Renin catalyzes the production of angiotensin, a
hormone that causes arterioles to constrict, raising
blood pressure. This also causes water retention.
How does this maintain homeostasis of blood
pressure?
Erythropoietin
 A second response to low blood pressure is the
release of erythropoietin, another hormone.
 Erythropoietin travels to the bone marrow and
stimulates the production of new blood cells. How
does this maintain homeostasis?
Amino acid metabolism Amino acids are the
building blocks of
protein. If not needed
for building protein,
then can be
metabolized for energy,
or broken apart and the
carbon chains used to
make fat.
 Metabolism requires
removal of the amine
unit (NH3).
Regulating water
 Antidiuretic hormone (ADH, also called
vasopressin) is part of a negative feedback system
that regulates water in the mammalian body.
 ADH increases the permeability of the distal tubule,
allowing greater water recovery.
Ammonia and Urea
 Ammonia is toxic and highly water soluble.
 The liver turns ammonia into urea, which is less
toxic and less soluble.
Urinary system anatomy
 Main structures of the urinary system:
 kidneys
 ureters
 bladder
 urethra
Anatomy of the Kidney
 Main structures of the mammalian kidney:
 renal cortex
 renal medula
 renal pelvis
 nephrons
Outline
 Uriniferous tubule (anatomical unit for forming urine)
 Nephron
 Renal corpuscle (in cortex)
 Glomerulus (tuft of capillaries)
 Glomerular (Bowman’s) capsule
 Tubular section
 Proximal convoluted tubule
 Loop of Henle
 Distal convoluted tubule
 Collecting duct
12
Anatomy of the Nephron
 Glomerulus
 Proximal tubule
 Loop of Henle
 Distal tubule
Glomerulus This is the only place
in the system where
the blood is actually
“filtered.”
 Blood pressure is
used to push plasma
through capillary
walls and into the
Bowman’s capsule.
Proximal tubule
 Nutrients (salts, vitamins, etc.) are moved out of the
tubule through active transport.
 Water follows the nutrients by osmosis.
Loop of Henle Tissue around the
Loop of Henle is
salty, from active
transport and
diffusion of
sodium chloride.
 The salty
conditions allow
water to diffuse out
of the loop.
Distal tubule
 Active transport
is used to move
more nutrients
out of the
concentrated
urine.
 Some ions,
drugs, and toxins
are actively
pumped into the
tubule.
Collecting Duct  More water
leaves the tube
by osmosis, since
the tube is
surrounded by
salty tissue.
 Some urea leaves
by diffusion, and
may be cycled
through the
system.
Vessels
 Afferent and efferent arterioles associated with glomerular capillaries
 Allows high pressure for forcing filtrate out of blood
 About 20% of renal plasma flow is filtered each minute : this is the glomerular filtration
rate (GFR), an important clinical measure of renal function
 This is about one liter every 8 minutes (only 1% ends up as urine)
 Peritubular capillaries arise from efferent arterioles
 Absorb solutes and water from tubule cells
20
21
The Vasa recta is a
portion of the
peritubular capillary
system which enters the
medulla where the solute
concentration in the
interstitium is high. It
acts with the loop of
Henle to concentrate the
urine by a complex
mechanism of counter
current exchange using
urea. If the vasa recta did
not exist, the high
concentration of solutes
in the medullary
interstitium would be
washed out.
22
____vasa recta
(vessels, continued)
The Vasa recta
For studying
23
Parts of the kidney:
1. Renal pyramid
2. Efferent vessel
3. Renal artery
4. Renal vein
5. Renal hilum
6. Renal pelvis
7. Ureter
8. Minor calyx
9. Renal capsule
10. Inferior renal capsule
11. Superior renal capsule
12. Afferent vessel
13. Nephron
14. Minor calyx
15. Major calyx
16. Renal papilla
17. Renal column
The Ureters
 Slender tubes leaving each
renal pelvis
 One for each kidney
carrying urine to the
bladder
 Run medially within
posterior bladder wall
before opening into
interior
 This oblique entry helps
prevent backflow of urine
24
Ureters play an active role in
transporting urine (it’s not
just by gravity)
Three basic layers
 Transitional epithelium
of mucosa stretches
when ureters fill
 Muscularis
 Inner longitudinal, outer
circular layers
 Inferior 3rd with extra
longitudinal layer)
 Stimulated to contract
when urine in ureter:
peristaltic waves to
propel urine to bladder
 Adventitia (external)
25
Urinary Bladder  Collapsible muscular
sac
 Stores and expels urine
 When full it become
ovoid.
 In male it is dorsaly
related to the rectum,
ductusdeference and
acessary sex glands
 In female it is related
with body of uterus and
vagina.
26
Urethra
 Extends to the tip of the
penis, where it exit the
body.
 Used to empty the
urinary blader.
 Surrounded by smooth
muscle crucial for
ejaculation.
Urinary System Of Goat(1)

Urinary System Of Goat(1)

  • 2.
    Urinary System OfGoat  Presented To:  Sir Zeeshan Akbar Sb.  Presented By:  14-Arid-2030  14-Arid-2029  14-Arid-2028  14-Arid-2036   DVM 1st (Evening)  Group (A)
  • 3.
    Homeostasis  The urinarysystem maintains homeostasis in several ways:  Removal of urea (nitrogenous waste) from the bloodstream.  Control of water and salt balance in the bloodstream.  Involved in blood pressure regulation.
  • 4.
    Renin  Renin isan enzyme released by the kidneys in response to a drop in blood pressure.  Renin catalyzes the production of angiotensin, a hormone that causes arterioles to constrict, raising blood pressure. This also causes water retention. How does this maintain homeostasis of blood pressure?
  • 5.
    Erythropoietin  A secondresponse to low blood pressure is the release of erythropoietin, another hormone.  Erythropoietin travels to the bone marrow and stimulates the production of new blood cells. How does this maintain homeostasis?
  • 6.
    Amino acid metabolismAmino acids are the building blocks of protein. If not needed for building protein, then can be metabolized for energy, or broken apart and the carbon chains used to make fat.  Metabolism requires removal of the amine unit (NH3).
  • 7.
    Regulating water  Antidiuretichormone (ADH, also called vasopressin) is part of a negative feedback system that regulates water in the mammalian body.  ADH increases the permeability of the distal tubule, allowing greater water recovery.
  • 9.
    Ammonia and Urea Ammonia is toxic and highly water soluble.  The liver turns ammonia into urea, which is less toxic and less soluble.
  • 10.
    Urinary system anatomy Main structures of the urinary system:  kidneys  ureters  bladder  urethra
  • 11.
    Anatomy of theKidney  Main structures of the mammalian kidney:  renal cortex  renal medula  renal pelvis  nephrons
  • 12.
    Outline  Uriniferous tubule(anatomical unit for forming urine)  Nephron  Renal corpuscle (in cortex)  Glomerulus (tuft of capillaries)  Glomerular (Bowman’s) capsule  Tubular section  Proximal convoluted tubule  Loop of Henle  Distal convoluted tubule  Collecting duct 12
  • 13.
    Anatomy of theNephron  Glomerulus  Proximal tubule  Loop of Henle  Distal tubule
  • 14.
    Glomerulus This isthe only place in the system where the blood is actually “filtered.”  Blood pressure is used to push plasma through capillary walls and into the Bowman’s capsule.
  • 15.
    Proximal tubule  Nutrients(salts, vitamins, etc.) are moved out of the tubule through active transport.  Water follows the nutrients by osmosis.
  • 16.
    Loop of HenleTissue around the Loop of Henle is salty, from active transport and diffusion of sodium chloride.  The salty conditions allow water to diffuse out of the loop.
  • 17.
    Distal tubule  Activetransport is used to move more nutrients out of the concentrated urine.  Some ions, drugs, and toxins are actively pumped into the tubule.
  • 18.
    Collecting Duct More water leaves the tube by osmosis, since the tube is surrounded by salty tissue.  Some urea leaves by diffusion, and may be cycled through the system.
  • 20.
    Vessels  Afferent andefferent arterioles associated with glomerular capillaries  Allows high pressure for forcing filtrate out of blood  About 20% of renal plasma flow is filtered each minute : this is the glomerular filtration rate (GFR), an important clinical measure of renal function  This is about one liter every 8 minutes (only 1% ends up as urine)  Peritubular capillaries arise from efferent arterioles  Absorb solutes and water from tubule cells 20
  • 21.
  • 22.
    The Vasa rectais a portion of the peritubular capillary system which enters the medulla where the solute concentration in the interstitium is high. It acts with the loop of Henle to concentrate the urine by a complex mechanism of counter current exchange using urea. If the vasa recta did not exist, the high concentration of solutes in the medullary interstitium would be washed out. 22 ____vasa recta (vessels, continued) The Vasa recta
  • 23.
    For studying 23 Parts ofthe kidney: 1. Renal pyramid 2. Efferent vessel 3. Renal artery 4. Renal vein 5. Renal hilum 6. Renal pelvis 7. Ureter 8. Minor calyx 9. Renal capsule 10. Inferior renal capsule 11. Superior renal capsule 12. Afferent vessel 13. Nephron 14. Minor calyx 15. Major calyx 16. Renal papilla 17. Renal column
  • 24.
    The Ureters  Slendertubes leaving each renal pelvis  One for each kidney carrying urine to the bladder  Run medially within posterior bladder wall before opening into interior  This oblique entry helps prevent backflow of urine 24
  • 25.
    Ureters play anactive role in transporting urine (it’s not just by gravity) Three basic layers  Transitional epithelium of mucosa stretches when ureters fill  Muscularis  Inner longitudinal, outer circular layers  Inferior 3rd with extra longitudinal layer)  Stimulated to contract when urine in ureter: peristaltic waves to propel urine to bladder  Adventitia (external) 25
  • 26.
    Urinary Bladder Collapsible muscular sac  Stores and expels urine  When full it become ovoid.  In male it is dorsaly related to the rectum, ductusdeference and acessary sex glands  In female it is related with body of uterus and vagina. 26
  • 27.
    Urethra  Extends tothe tip of the penis, where it exit the body.  Used to empty the urinary blader.  Surrounded by smooth muscle crucial for ejaculation.