Which of the following describes a polyprotein? Choose the best answer. During antigenic shift, hybrid infuenza viruses show new combinations of proteins that are not e recognized by the immune system. The poliovirus has a linear positive-strand RNA genome with a polyA tail similar to those found in eukaryotes. An HIV virus produces a large protein that contains multiple structure proteins and a protease. mRNAs from different segments of the influenza virus produce different proteins. Some of the archaeal RNA viruses had the genes to produce polyproteins. This suggests that they may have similarities in their lee cycles to known RNA viruses that use polyproteins. Solution The answer is: An HIV virus produces a large protein that contains multiple structure proteins and a protease. The protease later cleaves the polyprotein to form individual proteins..