This document compares Problem Based Learning (PBL) and Case Based Learning (CBL). PBL uses open inquiry with no pre-reading, while CBL provides pre-reading material and has the facilitator take a more active role. A study was conducted shifting two medical schools from PBL to CBL over 2-3 years. Students and faculty largely preferred CBL as it kept learning relevant and enhanced clinical skills with less busy work, though some faculty felt PBL better enhanced problem solving and self-directed learning.