This document describes using a random forest regression model to predict pIC50 values, which indicate how strongly compounds bind to the acetylcholinesterase enzyme, for novel drugs that could treat Alzheimer's disease. The model is trained on a dataset of over 5,000 compounds from the ChEMBL database with known pIC50 values. Fingerprint descriptors of the compounds are used as predictors in the random forest model. The model is validated using statistical metrics and deployed using a web application to allow users to upload compounds and receive predicted pIC50 values.