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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072
© 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 5409
SKIN CANCER DETECTION USING LOCAL AND GLOBAL CONTRAST
STRETCHING
Sana Baig1, Sakshi Gajbhiye2, Savi Ghode3 and Ms. Kiran Dange4
1,2,3Electronics, Maharashtra, India
4 Electronics and Communication, Maharashtra, India
---------------------------------------------------------------------***---------------------------------------------------------------------
Abstract - This paper aims to identify efficient image
enhancement techniques in order to detect preliminary effect
of skin cancer. The different techniques that can be used are
adaptive unsharp masking, adaptive histogram equalization,
adaptive neighborhood technique and local and global
contrast stretching. The main technique whichwearegoing to
focus is local and global contrast stretching. We consider this
technique for its advanced output. In this we present result
using this technique on color and gray scale image. The result
is obtain by scanning the input image through the database
and it calculates the parameters. Through this calculated
parameters we can find out whether the image iscancerous or
not.
Key Words: ImageEnhancementTechnique,Skincancer,
Unsharp Masking, Adaptive histogram equalization,
Adaptive neighbourhood technique, Local and Global
Contrast Stretching.
1. INTRODUCTION
Most of the skin cancer is caused in summer. One million
people are detected with skin cancer every year. 70,000
people get melanoma that is deadliest formofdisease. There
are two type of skincancermelanoma andnon-melanoma.To
obtain required quality through various method image
enhancement technique is used for processing of digital
image. In order to detect the preliminary effectofskincancer
efficient image enhancement techniques are used. Image
enhancement technique provide improvement of object
detection and identification under low illumination
condition. This is used to make an image lighter and darker.
Contrast enhancement is most common method for
enhancing the image. The objective of image enhancement is
for the improvement of visual quality and clarity of image.
Cancer detection is process of recognizing the earlystages of
cancer and possible warning sign of the disease. Earlyaction
can help to diagnose the disease as soon as possible for best
recovery of cancer. It can be detected with thehelpof mobile
application. It will be very easy for patient as they scan the
images of effected part and with the help of database it will
help detect skin cancer.
2. LITERATURE SURVEY
1. Dr Vijay Dhir and Sanjeev kumar Review of various
Contrast Image Enhancement Technique. This paper
studies various contrast image enhancementtechnique.
This various technique will going improve the contrast
of an image.
2. Jaspreet Kaur and Amita Choudhary Comparision of
Sevral Contrast Stretching method on Acute Leukemia
Image. This paper focuseson variouscontraststretching
methods such as local ,global ,partial, bright and dark
contrast stretching methods. The comparison of all this
method studied in this paper to nd out which oneis best
to enhance and study acute leukemia image in better
way.
3. Archana Singh and Neeraj Kumar A Comprehensive
method forContrastImageEnhancementbasedonLocal
and Global Contrast and Local standard Deviation. This
paper studies global and local method for Contrast
image Enhancement .This paper study this two method
in which researcher found that this two are not sucient
to enhance an image when image has some contrast
area and it is not possible to perform any type of
transformation on it. This paper proposed and study a
novel method to remove the divided by zero condition
that arises due to local standard deviation of that
contrast area to enhance the image in more suitable
way.
4. Prasad Nagelli, Venkath Reddy, BTR Naresh Reddy
Blurred Image Enhancement using Contrast Stretching
,Local Edge Detection and blind decovolution. This
paper is research work to avoid the problem which will
occur in blurred image .Blurred image is a common
problem observed in the situation when object is in
motion or when we will going to shoot a video. Three
method are presented here in this paper to avoid the
problem of blurred image.Contraststretchingprocessis
used to deblurred image.Local edgedetectionmethodis
applied on original as well as blurred image. Both the
image edges are fused to obtain sharp edgesofanimage
as an output. Fused image distortion is unknown so
blind deconvolution technique is applied to obtain final
output
3. LOCAL AND GLOBAL CONTRAST STRETCHING
The enhancement techniques are developed in order to
increase the contrast of an image. Generally, animagecanbe
enhanced by spreading out the range of scene illumination.
This procedure is called contrast stretching. Contrast
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072
© 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 5410
normalization is a simpleimageenhancementtechnique that
attempts to improve the contrast in an image by stretching
the range of intensity values it contains to span a desired
range of values, the full range of pixel values that the image
type concerned allows. Contrast stretching changes the
distribution and range of the digital numbers assigned to
each pixel in an image. This is normally donetoaccentimage
details that may be difficult for thehumanviewertoobserve.
Our main goal in this paper is to apply a contrast
enhancement technique to recover an image from blurred
images, also improve image quality of it.
Fig -1: Block diagram of local and global contrast
stretching
4. PROPOSED THEORY
The proposed theory for melanoma and non-melanoma skin
cancer detection by using image enhancement techniques is
shown in following flow diagram. The input image of wound
which we want to detect where skin cancer is present or not
is given to the Graphical User Interface (GUI).GUI has main
function which integrates multiple functional module. This
functional module can be feature extraction module, noise
adding and noise denoising module. We are enhancing the
image in following process:
1. Edge detection
2. Color detection
3. Segmented image
4. Lesion detection
After going through the above process we get various result
which is useful for prediction of image which is cancerousor
noncancerous.
A. Edge Detection
In edge detection, first we take input which is in rgb format
converted to gray scale image. Gray scale image have many
shades of gray in which each pixel is a single sample
represent amount of light gives informationabout intensity.
This intensity lies between 0 to 255 range. Black shade has
weakest intensity i.e. 0 and white shade has strongest
intensity up to 255 range. Gaussian filter is apply to gray
scale image for smoothening. In Gaussian filter, with the
help of sigma factor, we get smooth image which is noise
free. This process increases standard deviation of that
image. Smooth image is converted to binary image which
pixels are only in black and white color by using
morphological operator we can clear all the holes in image.
We get number of pixels of black color as well as white
color. We are using canny edge type of edge detection in
which it will extract only useful information from different
vision of object and reduces unwanted data.
B. Color Detection
In second process of color detection, Hue saturation
value(HSV) model is apply after edgedetectioninwhichany
object with any color can be detected and reduces light
intensity from outside.
C. Segmented Image
Image segmentation is the process of one digital image into
multiple segmented parts (that means set of pixels calledas
super pixel) .Segmentation is used to locate only particular
object and edges of an image.
D. Lesion Detection
Lesion is a term to detect whether the image is cancerous
and non-cancerous.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072
© 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 5411
Fig -2: Result of proposed theory
5. SOFTWARE IMPLEMENTATION
Fig -3: Calculated Parameters of figure 2
A. L1 NORM
L1 Norm is the area of non-overlap region along major axis
of lesion B.
B. L2 NORM
L2 Norm is the area of non-overlap region along minor axis
of lesion
C. MEAN DEVIATION
Mean Deviation can be calculated by the formula below,
where, pi= Probability of occurrence of gray level i.
D.ASYMMETRY
Symmetry is one of the very important features in image
analysis. If the half part is missing or noisy, then by using
symmetry feature full pattern can be obtained and rid the
noisy part. Degree of symmetry can be checked using the
Asymmetry Index. It is calculated using below formula,
E.SYMMETRY INDEX
Symmetry index=A1+A2/Ar
A1=Area of non-overlap region along major axis of lesion
A2=Area of non-overlap region along minor axis of lesion
Ar=lesion implementation
F.BORDER IRREGULARITY
There are three different measures such as compact index
(CI), fractional dimensions and edge variations
CI=2PL=4AL-[1]
where, PL=perimeter of lesion
AL=Area of lesion
G. DIAMETER
Melanoma tends to grow larger than common moles, and
especially the diameter of 6mm. Because the wound is often
irregular forms, to find the diameter, draw from all the edge
pixels to the pixel edges through the midpoint andaveraged.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072
© 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 5412
H. COLOUR
The emergence of color variation in the color is early sign of
melanoma. Becausemelanoma cellsgrowingrowerpigment,
they are often colorful aroundbrown,orblack,depending on
the production of the melanin pigment at different depth in
the skin. The descriptors of color are mainly statistical
parameters calculated from different color channels, like
average value and standard deviation of the RGB or HSV
color channel. Here color varianceoftheRGBimagehasbeen
calculated using HSV channel.
I.SKEW
It was used to detect edges in dark objects on white
background, having a sign change at luminance edges.
J. KURTOSIS
It detects if a distribution is flat or peaky, and later was
associated to perceptual aspects of sparse coding. It is often
considered as a measure a sparsity, and used in early
deconvolution methods.
K. PEAK SIGNAL TO NOISE RATIO (PSNR)
PSNR is used to measure the quality of reconstruction of
lossy and lossless compression
L.TOTAL DERMOSCOPIC VALUE (TDV)
TDV= (A*1.3) + (B*0.1) +(C*0.5) + (D*0.5)-[2]
where, A=Asymmetry
B=Border
C=Color
D=Diameter
6. CONCLUSION
The basic techniquesofimageenhancementbyproviding the
result of different parts of skin affected by skin cancer. The
images are differentiated on the basis of different
parameters by concluding the image size and RGB values
with the enhanced form of the original image. The main idea
is to provide enhanced images through local and global
contrast stretching technique based on well-defined
parameters so that it can be helpful for doctors and other
medical practitioners to conclude the result and use this
technique to cure cancer
REFERENCES
[1]AshishSaxena,RajeevSaxena,YogadharPandey,AnExhausti
veAnalysis On Various Foggy Image Enhancement
Techniques, International Journal of Advanced Research in
Computer Science and Electronics Engineering (IJARCSEE)
Volume 3, Issue 1, January 2014
[2] Abhishek Tiwari, Pramil Singh, Analysis of Color
Contrast Enhancement Techniques, International Journal of
Emerging Technology and Advanced Engineering
Website:2008 Certified Journal, Volume 4, Issue 4, April
2014
[3] Wanhyun Cho, SeongchaeSeo, Jinho You, Soonja Kang,
Enhancement Technique of Image Contrast using New
Histogram Transformation, Journal of Computer and
Communications, 2014, 2, 52-56
[4] Raju.A, Dwarakish. G. S, D. Venkat Reddy, A Comparative
Analysis of Histogram Equalization based Techniques for
Contrast Enhancement and Brightness Preserving,
International Journal of Signal Processing, ImageProcessing
and Pattern Recognition Vol.6, No.5 (2013)
[5] Suneetha, Dr.T. Venkateswarlu, Enhancement
Techniques for Gray scale Images in Spatial Domain,
International Journal of Emerging TechnologyandAdvanced
Engineering Website: www.ijetae.com (ISSN 2250-2459,
Volume 2, Issue 4, April 2012)
[6] S. SomorjeetSingh,Th. Tangkeshwar Singh, H. Mamata
Devi, TejmaniSinam, Local Contrast Enhancement using
Local Standard Deviation, International Journal ofComputer
Applications (0975 888)Volume 47 No.15, June 2012
[7] ShyamLal, Mahesh Chandra, Efficient Algorithm for
Contrast Enhancement of Natural Images,Received April 21,
2012; Accepted August 10, 2012
[8] Sapana S. Bagade, Vijaya K. Shandilya, Use of histogram
Equalization in Image Processing For Image Enhancement,
International Journal of Software Engineering Research
Practices Vol.1, Issue 2, April, 2011
[9] Fabrizio Russo, an Image Enhancement Technique
Combining Sharpening and Noise Reduction, IEEE
TRANSACTIONS ON INSTRUMENTATION AND
MEASUREMENT, VOL. 51, NO. 4, AUGUST 2002
[10] RadhikaSivaramakrishna, Nancy A. Obuchowski,
William A. Chilcote, Gilda Cardenosa, Kimerly A. Powell,
Comparing the Performance of Mammographic
Enhancement Algorithms: A Preference Study,AJR:175,July
2000
[11] Sudhamony S,Binu P J,Satheesh G,IssacNiwas
S,SudalaimaniC,Nandakumar K,Muralidharan V and Baljit
Singh Bedi, Nationwide Tele-Oncology network in India - A
framework for implementation,200810thIEEEIntl.Conf. on
e-Health Networking, Applications and Service
(HEALTHCOM 2008)

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IRJET- Skin Cancer Detection using Local and Global Contrast Stretching

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 5409 SKIN CANCER DETECTION USING LOCAL AND GLOBAL CONTRAST STRETCHING Sana Baig1, Sakshi Gajbhiye2, Savi Ghode3 and Ms. Kiran Dange4 1,2,3Electronics, Maharashtra, India 4 Electronics and Communication, Maharashtra, India ---------------------------------------------------------------------***--------------------------------------------------------------------- Abstract - This paper aims to identify efficient image enhancement techniques in order to detect preliminary effect of skin cancer. The different techniques that can be used are adaptive unsharp masking, adaptive histogram equalization, adaptive neighborhood technique and local and global contrast stretching. The main technique whichwearegoing to focus is local and global contrast stretching. We consider this technique for its advanced output. In this we present result using this technique on color and gray scale image. The result is obtain by scanning the input image through the database and it calculates the parameters. Through this calculated parameters we can find out whether the image iscancerous or not. Key Words: ImageEnhancementTechnique,Skincancer, Unsharp Masking, Adaptive histogram equalization, Adaptive neighbourhood technique, Local and Global Contrast Stretching. 1. INTRODUCTION Most of the skin cancer is caused in summer. One million people are detected with skin cancer every year. 70,000 people get melanoma that is deadliest formofdisease. There are two type of skincancermelanoma andnon-melanoma.To obtain required quality through various method image enhancement technique is used for processing of digital image. In order to detect the preliminary effectofskincancer efficient image enhancement techniques are used. Image enhancement technique provide improvement of object detection and identification under low illumination condition. This is used to make an image lighter and darker. Contrast enhancement is most common method for enhancing the image. The objective of image enhancement is for the improvement of visual quality and clarity of image. Cancer detection is process of recognizing the earlystages of cancer and possible warning sign of the disease. Earlyaction can help to diagnose the disease as soon as possible for best recovery of cancer. It can be detected with thehelpof mobile application. It will be very easy for patient as they scan the images of effected part and with the help of database it will help detect skin cancer. 2. LITERATURE SURVEY 1. Dr Vijay Dhir and Sanjeev kumar Review of various Contrast Image Enhancement Technique. This paper studies various contrast image enhancementtechnique. This various technique will going improve the contrast of an image. 2. Jaspreet Kaur and Amita Choudhary Comparision of Sevral Contrast Stretching method on Acute Leukemia Image. This paper focuseson variouscontraststretching methods such as local ,global ,partial, bright and dark contrast stretching methods. The comparison of all this method studied in this paper to nd out which oneis best to enhance and study acute leukemia image in better way. 3. Archana Singh and Neeraj Kumar A Comprehensive method forContrastImageEnhancementbasedonLocal and Global Contrast and Local standard Deviation. This paper studies global and local method for Contrast image Enhancement .This paper study this two method in which researcher found that this two are not sucient to enhance an image when image has some contrast area and it is not possible to perform any type of transformation on it. This paper proposed and study a novel method to remove the divided by zero condition that arises due to local standard deviation of that contrast area to enhance the image in more suitable way. 4. Prasad Nagelli, Venkath Reddy, BTR Naresh Reddy Blurred Image Enhancement using Contrast Stretching ,Local Edge Detection and blind decovolution. This paper is research work to avoid the problem which will occur in blurred image .Blurred image is a common problem observed in the situation when object is in motion or when we will going to shoot a video. Three method are presented here in this paper to avoid the problem of blurred image.Contraststretchingprocessis used to deblurred image.Local edgedetectionmethodis applied on original as well as blurred image. Both the image edges are fused to obtain sharp edgesofanimage as an output. Fused image distortion is unknown so blind deconvolution technique is applied to obtain final output 3. LOCAL AND GLOBAL CONTRAST STRETCHING The enhancement techniques are developed in order to increase the contrast of an image. Generally, animagecanbe enhanced by spreading out the range of scene illumination. This procedure is called contrast stretching. Contrast
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 5410 normalization is a simpleimageenhancementtechnique that attempts to improve the contrast in an image by stretching the range of intensity values it contains to span a desired range of values, the full range of pixel values that the image type concerned allows. Contrast stretching changes the distribution and range of the digital numbers assigned to each pixel in an image. This is normally donetoaccentimage details that may be difficult for thehumanviewertoobserve. Our main goal in this paper is to apply a contrast enhancement technique to recover an image from blurred images, also improve image quality of it. Fig -1: Block diagram of local and global contrast stretching 4. PROPOSED THEORY The proposed theory for melanoma and non-melanoma skin cancer detection by using image enhancement techniques is shown in following flow diagram. The input image of wound which we want to detect where skin cancer is present or not is given to the Graphical User Interface (GUI).GUI has main function which integrates multiple functional module. This functional module can be feature extraction module, noise adding and noise denoising module. We are enhancing the image in following process: 1. Edge detection 2. Color detection 3. Segmented image 4. Lesion detection After going through the above process we get various result which is useful for prediction of image which is cancerousor noncancerous. A. Edge Detection In edge detection, first we take input which is in rgb format converted to gray scale image. Gray scale image have many shades of gray in which each pixel is a single sample represent amount of light gives informationabout intensity. This intensity lies between 0 to 255 range. Black shade has weakest intensity i.e. 0 and white shade has strongest intensity up to 255 range. Gaussian filter is apply to gray scale image for smoothening. In Gaussian filter, with the help of sigma factor, we get smooth image which is noise free. This process increases standard deviation of that image. Smooth image is converted to binary image which pixels are only in black and white color by using morphological operator we can clear all the holes in image. We get number of pixels of black color as well as white color. We are using canny edge type of edge detection in which it will extract only useful information from different vision of object and reduces unwanted data. B. Color Detection In second process of color detection, Hue saturation value(HSV) model is apply after edgedetectioninwhichany object with any color can be detected and reduces light intensity from outside. C. Segmented Image Image segmentation is the process of one digital image into multiple segmented parts (that means set of pixels calledas super pixel) .Segmentation is used to locate only particular object and edges of an image. D. Lesion Detection Lesion is a term to detect whether the image is cancerous and non-cancerous.
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 5411 Fig -2: Result of proposed theory 5. SOFTWARE IMPLEMENTATION Fig -3: Calculated Parameters of figure 2 A. L1 NORM L1 Norm is the area of non-overlap region along major axis of lesion B. B. L2 NORM L2 Norm is the area of non-overlap region along minor axis of lesion C. MEAN DEVIATION Mean Deviation can be calculated by the formula below, where, pi= Probability of occurrence of gray level i. D.ASYMMETRY Symmetry is one of the very important features in image analysis. If the half part is missing or noisy, then by using symmetry feature full pattern can be obtained and rid the noisy part. Degree of symmetry can be checked using the Asymmetry Index. It is calculated using below formula, E.SYMMETRY INDEX Symmetry index=A1+A2/Ar A1=Area of non-overlap region along major axis of lesion A2=Area of non-overlap region along minor axis of lesion Ar=lesion implementation F.BORDER IRREGULARITY There are three different measures such as compact index (CI), fractional dimensions and edge variations CI=2PL=4AL-[1] where, PL=perimeter of lesion AL=Area of lesion G. DIAMETER Melanoma tends to grow larger than common moles, and especially the diameter of 6mm. Because the wound is often irregular forms, to find the diameter, draw from all the edge pixels to the pixel edges through the midpoint andaveraged.
  • 4. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 5412 H. COLOUR The emergence of color variation in the color is early sign of melanoma. Becausemelanoma cellsgrowingrowerpigment, they are often colorful aroundbrown,orblack,depending on the production of the melanin pigment at different depth in the skin. The descriptors of color are mainly statistical parameters calculated from different color channels, like average value and standard deviation of the RGB or HSV color channel. Here color varianceoftheRGBimagehasbeen calculated using HSV channel. I.SKEW It was used to detect edges in dark objects on white background, having a sign change at luminance edges. J. KURTOSIS It detects if a distribution is flat or peaky, and later was associated to perceptual aspects of sparse coding. It is often considered as a measure a sparsity, and used in early deconvolution methods. K. PEAK SIGNAL TO NOISE RATIO (PSNR) PSNR is used to measure the quality of reconstruction of lossy and lossless compression L.TOTAL DERMOSCOPIC VALUE (TDV) TDV= (A*1.3) + (B*0.1) +(C*0.5) + (D*0.5)-[2] where, A=Asymmetry B=Border C=Color D=Diameter 6. CONCLUSION The basic techniquesofimageenhancementbyproviding the result of different parts of skin affected by skin cancer. The images are differentiated on the basis of different parameters by concluding the image size and RGB values with the enhanced form of the original image. The main idea is to provide enhanced images through local and global contrast stretching technique based on well-defined parameters so that it can be helpful for doctors and other medical practitioners to conclude the result and use this technique to cure cancer REFERENCES [1]AshishSaxena,RajeevSaxena,YogadharPandey,AnExhausti veAnalysis On Various Foggy Image Enhancement Techniques, International Journal of Advanced Research in Computer Science and Electronics Engineering (IJARCSEE) Volume 3, Issue 1, January 2014 [2] Abhishek Tiwari, Pramil Singh, Analysis of Color Contrast Enhancement Techniques, International Journal of Emerging Technology and Advanced Engineering Website:2008 Certified Journal, Volume 4, Issue 4, April 2014 [3] Wanhyun Cho, SeongchaeSeo, Jinho You, Soonja Kang, Enhancement Technique of Image Contrast using New Histogram Transformation, Journal of Computer and Communications, 2014, 2, 52-56 [4] Raju.A, Dwarakish. G. S, D. Venkat Reddy, A Comparative Analysis of Histogram Equalization based Techniques for Contrast Enhancement and Brightness Preserving, International Journal of Signal Processing, ImageProcessing and Pattern Recognition Vol.6, No.5 (2013) [5] Suneetha, Dr.T. Venkateswarlu, Enhancement Techniques for Gray scale Images in Spatial Domain, International Journal of Emerging TechnologyandAdvanced Engineering Website: www.ijetae.com (ISSN 2250-2459, Volume 2, Issue 4, April 2012) [6] S. SomorjeetSingh,Th. Tangkeshwar Singh, H. Mamata Devi, TejmaniSinam, Local Contrast Enhancement using Local Standard Deviation, International Journal ofComputer Applications (0975 888)Volume 47 No.15, June 2012 [7] ShyamLal, Mahesh Chandra, Efficient Algorithm for Contrast Enhancement of Natural Images,Received April 21, 2012; Accepted August 10, 2012 [8] Sapana S. Bagade, Vijaya K. Shandilya, Use of histogram Equalization in Image Processing For Image Enhancement, International Journal of Software Engineering Research Practices Vol.1, Issue 2, April, 2011 [9] Fabrizio Russo, an Image Enhancement Technique Combining Sharpening and Noise Reduction, IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, VOL. 51, NO. 4, AUGUST 2002 [10] RadhikaSivaramakrishna, Nancy A. Obuchowski, William A. Chilcote, Gilda Cardenosa, Kimerly A. Powell, Comparing the Performance of Mammographic Enhancement Algorithms: A Preference Study,AJR:175,July 2000 [11] Sudhamony S,Binu P J,Satheesh G,IssacNiwas S,SudalaimaniC,Nandakumar K,Muralidharan V and Baljit Singh Bedi, Nationwide Tele-Oncology network in India - A framework for implementation,200810thIEEEIntl.Conf. on e-Health Networking, Applications and Service (HEALTHCOM 2008)