Why is there no blood supply that extends into the epidermis? Thanks. Why is there no blood supply that extends into the epidermis? Thanks. Solution Answer: The epidermis has a stratified squamous epithelium, which normally undergoes ecdysis or moulting & do not require nutritious supply so that there no blood supply that extends into the epidermis. Epidermis is the outermost layer of the skin made of keratinized stratified squamous epithelial tissue in which outer or apical surface cells are hardened or dead. It does not contain blood vessels (not vascularized), and the dermal layer supplies oxygen and nutrients by means of diffusion. The layer of the epidermis that contains transulacent cells filled keratin are often referred as “thick stratum lucidum”. The other layers often sloughed off from the surface composed of dead cells that are flat and filled with keratin often referred as “stratum corneum”.