This document provides guidelines for cleaning protocols in hospitals. It discusses cleaning frequencies for different areas of the hospital based on factors like potential for patient contact, surface type, degree of hand contact, potential for contamination, and vulnerability of persons present. It recommends more frequent cleaning with disinfectants for high-risk areas like ICUs, OTs, and cleaning at least 3 times daily for patient care areas. General areas need cleaning twice daily. It also provides detailed cleaning frequencies and agents used for different hospital locations.