RPO America Peer Exchange: Rural Transportation Planning Programs
Regional framework for action to strengthen the public health response to substance use
1. Tehran,
Islamic Republic of Iran
14–17 October 2019
Agenda item 3(f)
Dr Khalid Saeed, Regional Adviser,
Mental Health and Neurological Disorders
Regional framework for action to
strengthen the public health
response to substance use
3. Target 3.5
Strengthen the
prevention and
treatment of
substance abuse,
including narcotic
drug abuse and
harmful use of
alcohol
The Sustainable Development Agenda,
anchored around 17 Sustainable
Development Goals (SDGs) and 169 targets,
is a universal, people-centred and planet-
sensitive agenda, with a set of goals and
targets, which outlines a roadmap to
transform our world
3
2015
2016
5. Mortality and disability-adjusted life years
(DALYs) attributable to drugs (by drug type)
2017
Type of
substance
Age-standardized
deaths
(per 100 000s)
Annual rate of
change in
deaths
attributable to
drug use (%)
Age-
standardized
DALYs
(per 100 000s)
Annual rate of
change in
DALYs
attributable to
drug use
(%)
Global Region Global Region Global Region Global Region
Opioids 4.78 5.09 433.0 723.0
Cannabis 0.17 0.14 18.6 13.6
Amphetamine
s
0.51 0.36 40.0 19.2
Cocaine 0.38 0.12 26.7 9.3
Other 0.60 0.27 42.4 17.1
All drugs 6.44 5.98 1.88 2.83 560.8 782.0 0.69 1.60
5
6. Mortality and disability-adjusted life years
(DALYs) attributable to drugs (by cause)
2017
Cause Age-standardized deaths
rates (per 100 000)
Age-standardized DALY
rates
(per 100 000)
Global Region Global Region
HIV 1.10 1.00 58.6 49.9
Hepatitis B 0.14 0.04 4.8 1.4
Hepatitis C 1.99 2.30 60.4 69.1
Drug use 2.27 1.42 371.5 589.4
Road injury 0.54 0.75 36.2 45.8
Suicide 0.53 0.46 29.3 26.7
All causes 6.44 5.98 560.8 782.2
6
8. Screening and brief
intervention in only 3
countries
Receive evidence-based
treatment
1 medication for detox 1 medication for maintenance
No specialized facilities
Outreach services for
people who inject drugs
Harm reduction programmes
8
9. Proposed regional framework for action to
strengthen the public health
response to substance use
Consensus following consultation with stakeholders to bridge implementation gap and
operationalize
recommendations made in UNGASS 2016 outcome document in line with WHO mandate
Overarching principles
• Evidence-based
• Multisectoral
• Life-course approach
• Promoting equity and observance
of rights
• Gender- and culture-sensitive
• Active engagement of civil society
• Integrated care delivery across the
continuum of care
9
11. Intervention Comments
Authoritative advice to physicians Some evidence it changes prescribing
behaviour
Restrict over the counter sales and monitor
prescription
May have some impact
Drug courts Reduces illicit drug use and related crime and
health problems
Primary level care
Screening and brief intervention Short-term reduction in drug use
Secondary/tertiary level care
Pharmacotherapy: Opioid replacement
therapy
Psychotherapy: CBT for cannabis, opioids
and psychostimulant dependence
Short-term impact
Reduces risk of overdose and opioid use
Harm reduction
Needle and syringe exchange, voluntary
counselling/testing for HIV/hepatitis C, oral
naltrexone and emergency naloxone
provision (opioid overdose), supervised
injecting facilities
Needle and syringe exchange may reduce
HIV infection but no effect on hepatitis C
infection
Healthsector
response
Evidence for policy options
Governan
ce
11
12. Evidence for policy options
Promotionand
prevention
Intervention Comments
Universal prevention
Skills and psychosocial interventions with primary
school children
Parenting skills training
Multicomponent community programme/prevention
in workplace
Good behaviour game: long-term
effects (up to 15 years)
Evidence from programmes for
employees with identified
substance use problems
Selective prevention
Skills training with adolescents
Early intervention with at-risk youth
Short-term effect
Short-term effects
Indicated prevention
Self-help and mutual aid groups
Peer self-help organizations
Very cost-effective in managing
chronic users
There is limited/no evidence for the effectiveness of mass media campaigns,
drug testing in schools, drug education, and only providing information
1
2
14. Governance
Develop/update national
substance use policies
and legislation(s)
Develop programmes
offering alternatives to
incarceration
International
cooperation
Promote active sharing
of information and
evidence
Monitoring &
surveillance
Develop a core set of
indicators
Health sector
response
Integrating screening and
brief intervention in
primary health care
Harm reduction
measures
Pharmacological and
psychosocial
interventions
Regulatory system for
prescription medicines
Prevention &
promotion
Parenting skills, family
strengthening, and life
skills education in
community, educational
and workplace settings
Proposed regional framework
1
4
15. The 66th session of the Regional Committee
is invited to endorse the proposed regional framework, which
incorporates the best available evidence-informed policy
options and cost-effective interventions to address the problem
of substance use
Conclusion
1
5
Editor's Notes
PICTURES
The substance use problem constitutes a serious threat to public health and to the safety, security and well‐being of humanity
It is inextricably linked with all aspects of the 2030 Agenda for Sustainable Development and humanitarian agendas, as indicated by the inclusion of a specific target (3.5) under SDG 3 to “strengthen the prevention and treatment of substance abuse, including narcotic drug abuse and harmful use of alcohol”
The outcome document of the 2016 United Nations General Assembly Special Session (UNGASS) on the world drug problem, acknowledges the need for a multidimensional, comprehensive, integrated and balanced approach to addressing and countering the drug problem, within the framework of the three international drug control conventions.
According to the WDR 2019, worldwide, around 271 million people are estimated to have used an illicit drug at least once during the preceding year, and some 35.3 million people who suffer from substance use disorders. These drugs are predominantly cannabinoids, opioids, cocaine, and/or amphetamine-type stimulants.
Prevalence of substance use varies greatly in the countries of the Region (12.6%-0.5%).
Cannabis is the drug most commonly used by the adult population with a median annual prevalence of 3.6%. The prevalence of opioid dependence in the Region is estimated to be 0.29%, which is higher than the global prevalence, while the estimated prevalence of cocaine and amphetamine dependence is similar to their estimated global prevalence. There are emerging trends in drug use in the Region, including use of tramadol and amphetamine-type substances such as Captagon (fenethylline). The emergence of newer psychotropic substances, particularly synthetic cannabinoids, has been reported in some countries; however, their use is relatively low in the Region
Substance use disorders account for about 0.5 million deaths globally and for 0.55% of the total global burden of disease (0.70% for men and 0.37% for women).
Although cannabis is still the most widely used drug globally, opioids account for 76% of deaths, and 75% of DALYs attributable to substance use disorders, globally as well as regionally.
The rate of change is significantly higher in the Eastern Mediterranean Region.
About 11.3 million people worldwide inject drugs. This subgroup endures the greatest health risks, with about 5.6 million individuals living with hepatitis C, 1.4 million people living with HIV, and 1.2 million people living with both these preventable conditions.
Highlight hepatitis C as cause of death and drug use disorders as cause of DALYs.
About 50% of countries either do not have any specialized treatment facilities or these are only available in the capital city.
Fewer than one in 7 people with a substance use disorder worldwide receive evidence-based treatment, while in countries of the Eastern Mediterranean Region only one in 13 receives treatment.
Screening and brief interventions are only available in < 10% of primary health care services in three countries.
Only 1/3 of countries have needle/syringe exchange programmes and condom distribution programmes.
Outreach services for injecting drug users are available in only 25% of countries.
63% of countries have at least one medication available for detoxification treatment.
50% of countries report the availability of at least one medication for maintenance treatment (either methadone, buprenorphine or buprenorphine/naloxone).
Strong leadership and governance at the national level are needed to provide an enabling environment to address the structural barriers to the implementation of policies and access to health services through supportive legislation, policy and financial commitment, and for considering alternatives to punishment for behaviours such as drug use (in full compliance with international drug control conventions), addressing stigma and discrimination (in the health sector and beyond), enhancing community empowerment, and addressing violence against key populations.
It is therefore important to consider policy and legislative alternatives that incorporate a public health perspective, and to shift the focus from supply-reduction measures to demand- and harm-reduction measures.
Drug treatment is increasingly being provided as an adjunct to the criminal justice system, or as an alternative to incarceration. The treatment of substance use disorders has been consistently shown to reduce illicit drug use and related crime and health problems such as HIV, and to facilitate reintegration into society. Cost-benefit analyses of substance use treatment have estimated that the returns on investment range from 7:1 to 18:1
Effective prevention starts early, and effective interventions and policies have been identified across many settings (family, school, community, workplace, health sector, and so on) and levels of risk (universal, selective and indicated).