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TOPIC :- DETAIL ABOUT CELL.
By :- SUMIT TIWARI
B.Pharm (AKTU)
M.Pharm (SRK)
4/5/2022
1
Lect.
sumit
tiwari
• CELL
 The cell (from Latin word 'cellula' meaning "small
room")
 the basic structural and functional unit of life.
 Every cell consists of a cytoplasm enclosed within
a membrane, which contains many biomolecules.
 such as :- proteins and nucleic acids
4/5/2022
2
Lect.
sumit
tiwari
• CELL BIOLOGY
 Cell biology is the study of cells, which were discovered
by Robert Hooke in 1665.
 Cell theory, first developed in 1839 by Matthias Jakob
Schleiden and Theodor Schwann , states that all
organisms are composed of one or more cells .
 that cells are the fundamental unit of structure and
function in all living organisms.
 Cells emerged on Earth about 4 billion years ago.
4/5/2022
3
Lect.
sumit
tiwari
• CELL TYPES
 Cells are of two types:
 Eukaryotic, which contain a nucleus.
 Prokaryotic , which do not have a nucleus, but a
nucleoid region is still present.
 Prokaryotes are single-celled organisms , while
Eukaryotes can be either single-celled or multicellular
4/5/2022
4
Lect.
sumit
tiwari
• PROKARYOTIC CELLS
 Prokaryotes include bacteria and archaea, two of
the three domains of life.
 Prokaryotic cells were the first form of life on Earth,
characterized by having vital biological
processes including cell signaling.
 They are simpler and smaller than eukaryotic cells, and
lack a nucleus, and other membrane-bound organelles.
4/5/2022
5
Lect.
sumit
tiwari
CONTD.
 The DNA of a prokaryotic cell consists of ,
single circular chromosome that is in direct contact with
the cytoplasm.
 The nuclear region in the cytoplasm is called
the nucleoid.
 Most prokaryotes are the smallest of all organisms
ranging from 0.5 to 2.0 μm in diameter
4/5/2022
6
Lect.
sumit
tiwari
• EUKARYOTIC CELLS
 Plants , animals, fungi, slime moulds , protozoa, and algae are
all eukaryotic.
 These cells are about fifteen times wider than a typical
prokaryote and can be as much as a thousand times greater in
volume.
 The main distinguishing feature of eukaryotes as compared to
prokaryotes- is compartmentalization.
 the presence of membrane-bound organelles (compartments)
in which specific activities take place.
4/5/2022
7
Lect.
sumit
tiwari
• SUBCELLULAR COMPONENTS
 All cells, whether prokaryotic or eukaryotic :-
 Have a membrane that envelops the cell.
 that regulates what moves in and out (selectively
permeable), and maintains the electric potential of the
cell.
 Inside the membrane, the cytoplasm takes up most of the
cell's volume.
4/5/2022
8
Lect.
sumit
tiwari
• CELL MEMBRANE
 The cell membrane, or plasma membrane, is a
selectively permeable.
 Biological membrane that surrounds the cytoplasm
of a cell.
 In animals, the plasma membrane is the outer
boundary of the cell.
 while in plants and prokaryotes it is usually covered
by a cell wall.
4/5/2022
9
Lect.
sumit
tiwari
CONTD.
 This membrane serves to separate and protect a cell from
its surrounding environment and is made mostly from
a double layer of phospholipids,
 which are amphiphilic (partly hydrophobic and
partly hydrophilic).
 Hence, the layer is called a phospholipid bilayer, or
sometimes a fluid mosaic membrane.
4/5/2022
10
Lect.
sumit
tiwari
• CYTOSKELETON
 The cytoskeleton acts to organize and maintain the cell's
shape.
 organelles in place.
 Helps during endocytosis ,the uptake of external
materials by a cell .
 cytokinesis, the separation of daughter cells after cell
division, and moves parts of the cell in processes of
growth and mobility.
4/5/2022
11
Lect.
sumit
tiwari
• GENETIC MATERIAL
 Two different kinds of genetic material exist:
 deoxyribonucleic acid (DNA) and ribonucleic
acid (RNA).
 Cells use DNA for their long-term information storage.
4/5/2022
12
Lect.
sumit
tiwari
• ORGANELLES
 Organelles are parts of the cell which are adapted and/or
specialized for carrying out one or more vital functions,
analogous to the organs of the human body (such as the
heart, lung, and kidney, with each organ performing a
different function).
 Both eukaryotic and prokaryotic cells have organelles,
but prokaryotic organelles are generally simpler and are
not membrane-bound.
4/5/2022
13
Lect.
sumit
tiwari
• EUKARYOTIC ORGANELLS.
 Cell nucleus: A cell's information center, the cell
nucleus is the most conspicuous organelle found in
a eukaryotic cell.
 It houses the cell's chromosomes, and is the place where
almost all DNA replication and RNA synthesis
(transcription) occur.
 The nucleus is spherical and separated from the
cytoplasm by a double membrane called the nuclear
envelope.
4/5/2022
14
Lect.
sumit
tiwari
CONTD.
 Mitochondria and chloroplasts: generate energy for the
cell.
 Mitochondria are self-replicating organelles that occur
in various numbers, shapes, and sizes in the cytoplasm of
all eukaryotic cells.
 Respiration occurs in the cell mitochondria, which
generate the cell's energy by oxidative phosphorylation ,
using oxygen to release energy stored in cellular
nutrients (typically pertaining to glucose) to
generate ATP.
 Mitochondria multiply by binary fission , like
prokaryotes
4/5/2022
15
Lect.
sumit
tiwari
CONTD.
 Endoplasmic reticulum: The endoplasmic reticulum (ER) is
a transport network for molecules targeted for certain
modifications and specific destinations, as compared to
molecules that float freely in the cytoplasm.
 The ER has two forms: the rough ER, which has ribosomes on
its surface that secrete proteins into the ER, and the smooth
ER, which lacks ribosomes.
 The smooth ER plays a role in calcium sequestration and
release.
4/5/2022
16
Lect.
sumit
tiwari
CONTD.
 Golgi apparatus: The primary function of the Golgi
apparatus is to process and package the macromolecules.
 such as proteins and lipids that are synthesized by the
cell.
4/5/2022
17
Lect.
sumit
tiwari
CONTD.
 Lysosomes and
peroxisomes: Lysosomes contain digestive
enzymes (acid Hydrolases ).
 They digest excess or worn-out organelles, food
particles, and engulfed viruses or bacteria .
 Peroxisomes have enzymes that rid the cell of
toxic peroxides.
 The cell could not house these destructive enzymes
if they were not contained in a membrane-bound
system.
4/5/2022
18
Lect.
sumit
tiwari
CONTD.
 Centrosome: the cytoskeleton organiser:
The centrosome produces the microtubules of a cell – a key
component of the cytoskeleton.
 It directs the transport through the ER and the . Golgi
apparatus
 Centrosomes are composed of two centrioles, which separate
during cell division and help in the formation of the mitotic
spindle.
 A single centrosome is present in the animal cells. They are
also found in some fungi and algae cells.
4/5/2022
19
Lect.
sumit
tiwari
CONTD.
 Vacuoles: Vacuoles sequester waste products and in
plant cells store water. They are often described as liquid
filled space and are surrounded by a membrane. Some
cells, most notably Amoeba , have contractile vacuoles,
which can pump water out of the cell if there is too much
water. The vacuoles of plant cells and fungal cells are
usually larger than those of animal cells.
4/5/2022
20
Lect.
sumit
tiwari
CONTD.
 Eukaryotic and prokaryotic
 Ribosomes:
 The ribosome is a large complex
of RNA and protein molecules.
 They each consist of two subunits, and act as an assembly line
where RNA from the nucleus is used to synthesise proteins
from amino acids.
 Ribosomes can be found either floating freely or bound to a
membrane (the rough endoplasmatic reticulum in eukaryotes,
or the cell membrane in prokaryotes).
4/5/2022
21
Lect.
sumit
tiwari
• STRUCTURES OUTSIDE THE CELL MEMBRANE
 Many types of prokaryotic and eukaryotic cells have
a cell wall.
 The cell wall acts to protect the cell mechanically and
chemically from its environment, and is an additional
layer of protection to the cell membrane.
 Different types of cell have cell walls made up of
different materials; plant cell walls are primarily made up
of cellulose, fungi cell walls are made up of chitin and
bacteria cell walls are made up of peptidoglycan.
4/5/2022
22
Lect.
sumit
tiwari
PART-1
THANK YOU !
4/5/2022
23
Lect.
sumit
tiwari

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Cell :- detailed about cell and their constituent.

  • 1. TOPIC :- DETAIL ABOUT CELL. By :- SUMIT TIWARI B.Pharm (AKTU) M.Pharm (SRK) 4/5/2022 1 Lect. sumit tiwari
  • 2. • CELL  The cell (from Latin word 'cellula' meaning "small room")  the basic structural and functional unit of life.  Every cell consists of a cytoplasm enclosed within a membrane, which contains many biomolecules.  such as :- proteins and nucleic acids 4/5/2022 2 Lect. sumit tiwari
  • 3. • CELL BIOLOGY  Cell biology is the study of cells, which were discovered by Robert Hooke in 1665.  Cell theory, first developed in 1839 by Matthias Jakob Schleiden and Theodor Schwann , states that all organisms are composed of one or more cells .  that cells are the fundamental unit of structure and function in all living organisms.  Cells emerged on Earth about 4 billion years ago. 4/5/2022 3 Lect. sumit tiwari
  • 4. • CELL TYPES  Cells are of two types:  Eukaryotic, which contain a nucleus.  Prokaryotic , which do not have a nucleus, but a nucleoid region is still present.  Prokaryotes are single-celled organisms , while Eukaryotes can be either single-celled or multicellular 4/5/2022 4 Lect. sumit tiwari
  • 5. • PROKARYOTIC CELLS  Prokaryotes include bacteria and archaea, two of the three domains of life.  Prokaryotic cells were the first form of life on Earth, characterized by having vital biological processes including cell signaling.  They are simpler and smaller than eukaryotic cells, and lack a nucleus, and other membrane-bound organelles. 4/5/2022 5 Lect. sumit tiwari
  • 6. CONTD.  The DNA of a prokaryotic cell consists of , single circular chromosome that is in direct contact with the cytoplasm.  The nuclear region in the cytoplasm is called the nucleoid.  Most prokaryotes are the smallest of all organisms ranging from 0.5 to 2.0 μm in diameter 4/5/2022 6 Lect. sumit tiwari
  • 7. • EUKARYOTIC CELLS  Plants , animals, fungi, slime moulds , protozoa, and algae are all eukaryotic.  These cells are about fifteen times wider than a typical prokaryote and can be as much as a thousand times greater in volume.  The main distinguishing feature of eukaryotes as compared to prokaryotes- is compartmentalization.  the presence of membrane-bound organelles (compartments) in which specific activities take place. 4/5/2022 7 Lect. sumit tiwari
  • 8. • SUBCELLULAR COMPONENTS  All cells, whether prokaryotic or eukaryotic :-  Have a membrane that envelops the cell.  that regulates what moves in and out (selectively permeable), and maintains the electric potential of the cell.  Inside the membrane, the cytoplasm takes up most of the cell's volume. 4/5/2022 8 Lect. sumit tiwari
  • 9. • CELL MEMBRANE  The cell membrane, or plasma membrane, is a selectively permeable.  Biological membrane that surrounds the cytoplasm of a cell.  In animals, the plasma membrane is the outer boundary of the cell.  while in plants and prokaryotes it is usually covered by a cell wall. 4/5/2022 9 Lect. sumit tiwari
  • 10. CONTD.  This membrane serves to separate and protect a cell from its surrounding environment and is made mostly from a double layer of phospholipids,  which are amphiphilic (partly hydrophobic and partly hydrophilic).  Hence, the layer is called a phospholipid bilayer, or sometimes a fluid mosaic membrane. 4/5/2022 10 Lect. sumit tiwari
  • 11. • CYTOSKELETON  The cytoskeleton acts to organize and maintain the cell's shape.  organelles in place.  Helps during endocytosis ,the uptake of external materials by a cell .  cytokinesis, the separation of daughter cells after cell division, and moves parts of the cell in processes of growth and mobility. 4/5/2022 11 Lect. sumit tiwari
  • 12. • GENETIC MATERIAL  Two different kinds of genetic material exist:  deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).  Cells use DNA for their long-term information storage. 4/5/2022 12 Lect. sumit tiwari
  • 13. • ORGANELLES  Organelles are parts of the cell which are adapted and/or specialized for carrying out one or more vital functions, analogous to the organs of the human body (such as the heart, lung, and kidney, with each organ performing a different function).  Both eukaryotic and prokaryotic cells have organelles, but prokaryotic organelles are generally simpler and are not membrane-bound. 4/5/2022 13 Lect. sumit tiwari
  • 14. • EUKARYOTIC ORGANELLS.  Cell nucleus: A cell's information center, the cell nucleus is the most conspicuous organelle found in a eukaryotic cell.  It houses the cell's chromosomes, and is the place where almost all DNA replication and RNA synthesis (transcription) occur.  The nucleus is spherical and separated from the cytoplasm by a double membrane called the nuclear envelope. 4/5/2022 14 Lect. sumit tiwari
  • 15. CONTD.  Mitochondria and chloroplasts: generate energy for the cell.  Mitochondria are self-replicating organelles that occur in various numbers, shapes, and sizes in the cytoplasm of all eukaryotic cells.  Respiration occurs in the cell mitochondria, which generate the cell's energy by oxidative phosphorylation , using oxygen to release energy stored in cellular nutrients (typically pertaining to glucose) to generate ATP.  Mitochondria multiply by binary fission , like prokaryotes 4/5/2022 15 Lect. sumit tiwari
  • 16. CONTD.  Endoplasmic reticulum: The endoplasmic reticulum (ER) is a transport network for molecules targeted for certain modifications and specific destinations, as compared to molecules that float freely in the cytoplasm.  The ER has two forms: the rough ER, which has ribosomes on its surface that secrete proteins into the ER, and the smooth ER, which lacks ribosomes.  The smooth ER plays a role in calcium sequestration and release. 4/5/2022 16 Lect. sumit tiwari
  • 17. CONTD.  Golgi apparatus: The primary function of the Golgi apparatus is to process and package the macromolecules.  such as proteins and lipids that are synthesized by the cell. 4/5/2022 17 Lect. sumit tiwari
  • 18. CONTD.  Lysosomes and peroxisomes: Lysosomes contain digestive enzymes (acid Hydrolases ).  They digest excess or worn-out organelles, food particles, and engulfed viruses or bacteria .  Peroxisomes have enzymes that rid the cell of toxic peroxides.  The cell could not house these destructive enzymes if they were not contained in a membrane-bound system. 4/5/2022 18 Lect. sumit tiwari
  • 19. CONTD.  Centrosome: the cytoskeleton organiser: The centrosome produces the microtubules of a cell – a key component of the cytoskeleton.  It directs the transport through the ER and the . Golgi apparatus  Centrosomes are composed of two centrioles, which separate during cell division and help in the formation of the mitotic spindle.  A single centrosome is present in the animal cells. They are also found in some fungi and algae cells. 4/5/2022 19 Lect. sumit tiwari
  • 20. CONTD.  Vacuoles: Vacuoles sequester waste products and in plant cells store water. They are often described as liquid filled space and are surrounded by a membrane. Some cells, most notably Amoeba , have contractile vacuoles, which can pump water out of the cell if there is too much water. The vacuoles of plant cells and fungal cells are usually larger than those of animal cells. 4/5/2022 20 Lect. sumit tiwari
  • 21. CONTD.  Eukaryotic and prokaryotic  Ribosomes:  The ribosome is a large complex of RNA and protein molecules.  They each consist of two subunits, and act as an assembly line where RNA from the nucleus is used to synthesise proteins from amino acids.  Ribosomes can be found either floating freely or bound to a membrane (the rough endoplasmatic reticulum in eukaryotes, or the cell membrane in prokaryotes). 4/5/2022 21 Lect. sumit tiwari
  • 22. • STRUCTURES OUTSIDE THE CELL MEMBRANE  Many types of prokaryotic and eukaryotic cells have a cell wall.  The cell wall acts to protect the cell mechanically and chemically from its environment, and is an additional layer of protection to the cell membrane.  Different types of cell have cell walls made up of different materials; plant cell walls are primarily made up of cellulose, fungi cell walls are made up of chitin and bacteria cell walls are made up of peptidoglycan. 4/5/2022 22 Lect. sumit tiwari