Pharmaceutical sciences

1. Govt. Collage of Pharmacy Karad
Seminar on
3D Printing of Pharmaceuticals
Presented by
Miss. Shraddha Patil
Under Guidance of
Prof. Dr. A.H.Hosmani Sir
Dept. of Pharmaceutics

2. 3 D Printing
❑ Introduction:
▪ 3D Printing or additive manufacturing is process of
making three dimensional solid object from a digital file.
▪ It was first developed by “Charls Haul” in 1984.
▪ Additive process on object created by laying dwon
successive layers of material until the entire object
created.
▪ Eg. Spritam , polypill.

3. ❑ How it works
➢ A virtual design of the object is created.
➢ CAD (Computer Aided Design) used a 3D modeling
program.
➢ The software slices the final model into hundreds or
thousand of horizontal layer.
➢ Printer creates the object layer by result in one 3
dimensional object.

4. ❑ Common types of 3D Printers
• The types of 3D printer chosen for an application often
depends on the material to be used and how in the
finished product are bonded.
The most commonly used 3D printing technology in
medical application are:
1. Stereolithography (SLA)
2. Selective laser Sintering (SLS)
3. Fused Deposition modeling (FMD)
4. Thermal Inkjet (TIJ) Printing

5. 1. Sterolithography
➢ First printing technique of 3D system
➢ Resin or acrylate was used which cured by UV laser.
➢ It build object One layer at a time by tracing laser
beam on surface of vat of liquid photopolymer.

6. Fig. Sterolithography

7. 2. Selective Laser Sintering (SLS)
➢ It is quick manufacturing process based on use of
powder coated metal additive.
➢ Laser beam used as heating source.
➢ After scanning first layer, scanning of second layer
continue which place over the first.

8. fig .Selective Laser Sintering

9. 3. Fused Deposition Modeling
eg. Thermoplastics polymer

10. 4. Inkjet Printer
1. Thermal Inkjet Printer
2. Piezoelectric Inkjet Printer
▪ Characteristics of starting material
✓ Particle size < 1 µm -To avoid clogging
✓ Viscosity < 20 cp
✓ Surface tension 30 -70 nm/m.

11. ❖ 3D Printer Material
1. Acrylonitrile Butadien Styrene.
• Advantage : very durable, flexible , lightweight
• Disadvantage : Require high temp.
2. Polylactic Acid
Biodegradable Thermoplastic
3. High Impact polystyrene
well spread in food industry for packaging.

12. Advantages
❖High production rate due to its fast opening system .
❖3D saves times and cost
❖Clean process, Reduction of material wastage which
can save in the cost of production.
❖Customization : A major advantage of 3D printing .
With a raw material, a blue print & a 3D printing, one
can print any design no matter how complex it might
be.
❖Constant phototyping & increased productivity : It
enables quick production with high number of
prototypes or small scale versions.
❖Better communication between the designer & user.

13. Disadvantages
❖High machinery cost.
❖Unsuitability to very large product.
❖Difficult to remove or install manually.
❖Mechanical issues.
❖Component do not have enough strength .
❖Limited raw materials .
❖Production of dangerous items.

14. Medical Application of 3D Printing

15. The Schematic picture of the general
pharmaceutical additive manufacturing processing.

16. Telepharmacy
Definition:- “ The provision of pharmacist care by
registered pharmacist & pharmacies through the use of
telecommunication to patient located at a distance.”
They may not have direct contact with pharmacist
It includes
 Drug therapy monitoring
 Patient counselling
 Prior authorization & refill authorization for prescription
drug

17. Working of Telepharmacy
• Prescription arrives at rural area and filled.
• Rural centre is connected with urban area
• Central pharmacist reviews the prescription.
• Release the appropriate items to rural & label.
• Barcode is scanned at rural to ensure that it matched
with label.
• Medication is supplied to patient with attached label.

18. Patient Consideration
 It is important that patient are comfortable with the
telepharmacy technology prior to receiving services.
Consideration should be given to formally marketing the
telepharmacy concept to the public prior to
implementing services.
 This can help the patient & public feel more comfortable
& willing to use the services. Special attention &
consideration should be given to orientation & education
of senior citizens who have not been exposed to or do
not have, extensive experience with technology.

19. Challenges In Implementation Of Telemedicine In
India
 Acceptance of the modality
 Financial unavailability
 Literacy rate and diversity in language
 Technical constraints

20. Advantages
➢ Access to healthcare services
➢ Economic benefits
➢ Patient satisfaction
➢ Effective patient counselling
➢ Minimal scarcity of pharmacist