Personalised Medicine is a young but rapidly advancing field.
The term 'Personalised Medicine' is described as providing "the right patient with the right drug at the right dose at the right time".
The role of genomics in drug discovery and development.pdfTaimoor Khan
The role of genomics in this fast-paced world of pharmaceutical research is a powerful catalyst, revolutionizing the entire process. By harnessing the potential of genomics, scientists can uncover valuable insights into disease mechanisms, identify therapeutic targets, and accelerate the discovery and development of groundbreaking medicines. This article dives deep into the significance of genomics in drug discovery and development, highlighting well-known genomic-based drug development services that are driving the future of pharmaceutical therapies.
hi.friends this is my first slide presentation which contain the information about the PERSONALIZED MEDICINES.this is the future medicinal treatment so,I hope you people like my presentation.
Personalised Medicine is a young but rapidly advancing field.
The term 'Personalised Medicine' is described as providing "the right patient with the right drug at the right dose at the right time".
The role of genomics in drug discovery and development.pdfTaimoor Khan
The role of genomics in this fast-paced world of pharmaceutical research is a powerful catalyst, revolutionizing the entire process. By harnessing the potential of genomics, scientists can uncover valuable insights into disease mechanisms, identify therapeutic targets, and accelerate the discovery and development of groundbreaking medicines. This article dives deep into the significance of genomics in drug discovery and development, highlighting well-known genomic-based drug development services that are driving the future of pharmaceutical therapies.
hi.friends this is my first slide presentation which contain the information about the PERSONALIZED MEDICINES.this is the future medicinal treatment so,I hope you people like my presentation.
Pharmacogenomics, Pharmacogenetics and Pharmacokinetics Zohaib HUSSAIN
Introduction
With the information available about human genome and human proteome, it is now well understood that there are a lot of variations between individuals. These minor variations account for many differences like adverse drug reactions, which are responsible for many hospitalizations and casualties. The observed variable effect of drug is due to difference in sensitivity as some people need higher dose and some need lower dose to get similar therapeutic effect, but in some people drug has no therapeutic effects and in some it shows strong adverse reactions.
Current treatment approach is based on sign and symptoms but near future it will be based on genetic structure/ genome.
Genomics Data have great reasearch opportunities in near future.
The basic aspects of drug discovery starts from target discovery and validation further going to lead identification and optimization. In this particular slide discussion is regarding the target discovery and the tools that have been utilized in this process.
Personalized Medicine: Foundation, Applications, Challenges and Opportunities...The Lifesciences Magazine
Personalized medicine is a paradigm-shifting strategy that aims to give customized therapies based on individual features, genetic makeup, and distinct illness profiles in an era characterized by revolutionary developments in healthcare.
Pharmacogenomics is new science about how the systematic identification of all the human genes, their products, interindividual variation, intraindividual variation in expression and function over time affects drug response/metabolism, etc.
Improve drug safety and reduce ADRs. The presentation explained the advantages of pharmacogenomics. Explained Goals of Pharmacogen(etics)omics.
Pharmacogenomics is the branch of biochemistry in which study how an individual’s genetic inheritance affects the body response to drug. Pharmacogenomics is the intersection of genetics and pharmaceutical industry.
In this presentation a brief note is given about what is pharmacogenomics. Why different drugs work differently in different people. today pharmacogenomics, future of pharmacogenomics. also describe the future of pharmacogenomics. challenges which have to pharmacogenomics.
Pharmacogenomics, Pharmacogenetics and Pharmacokinetics Zohaib HUSSAIN
Introduction
With the information available about human genome and human proteome, it is now well understood that there are a lot of variations between individuals. These minor variations account for many differences like adverse drug reactions, which are responsible for many hospitalizations and casualties. The observed variable effect of drug is due to difference in sensitivity as some people need higher dose and some need lower dose to get similar therapeutic effect, but in some people drug has no therapeutic effects and in some it shows strong adverse reactions.
Current treatment approach is based on sign and symptoms but near future it will be based on genetic structure/ genome.
Genomics Data have great reasearch opportunities in near future.
The basic aspects of drug discovery starts from target discovery and validation further going to lead identification and optimization. In this particular slide discussion is regarding the target discovery and the tools that have been utilized in this process.
Personalized Medicine: Foundation, Applications, Challenges and Opportunities...The Lifesciences Magazine
Personalized medicine is a paradigm-shifting strategy that aims to give customized therapies based on individual features, genetic makeup, and distinct illness profiles in an era characterized by revolutionary developments in healthcare.
Pharmacogenomics is new science about how the systematic identification of all the human genes, their products, interindividual variation, intraindividual variation in expression and function over time affects drug response/metabolism, etc.
Improve drug safety and reduce ADRs. The presentation explained the advantages of pharmacogenomics. Explained Goals of Pharmacogen(etics)omics.
Pharmacogenomics is the branch of biochemistry in which study how an individual’s genetic inheritance affects the body response to drug. Pharmacogenomics is the intersection of genetics and pharmaceutical industry.
In this presentation a brief note is given about what is pharmacogenomics. Why different drugs work differently in different people. today pharmacogenomics, future of pharmacogenomics. also describe the future of pharmacogenomics. challenges which have to pharmacogenomics.
The dimensions of healthcare quality refer to various attributes or aspects that define the standard of healthcare services. These dimensions are used to evaluate, measure, and improve the quality of care provided to patients. A comprehensive understanding of these dimensions ensures that healthcare systems can address various aspects of patient care effectively and holistically. Dimensions of Healthcare Quality and Performance of care include the following; Appropriateness, Availability, Competence, Continuity, Effectiveness, Efficiency, Efficacy, Prevention, Respect and Care, Safety as well as Timeliness.
Leading the Way in Nephrology: Dr. David Greene's Work with Stem Cells for Ki...Dr. David Greene Arizona
As we watch Dr. Greene's continued efforts and research in Arizona, it's clear that stem cell therapy holds a promising key to unlocking new doors in the treatment of kidney disease. With each study and trial, we step closer to a world where kidney disease is no longer a life sentence but a treatable condition, thanks to pioneers like Dr. David Greene.
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdfSachin Sharma
This content provides an overview of preventive pediatrics. It defines preventive pediatrics as preventing disease and promoting children's physical, mental, and social well-being to achieve positive health. It discusses antenatal, postnatal, and social preventive pediatrics. It also covers various child health programs like immunization, breastfeeding, ICDS, and the roles of organizations like WHO, UNICEF, and nurses in preventive pediatrics.
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
Explore our infographic on 'Essential Metrics for Palliative Care Management' which highlights key performance indicators crucial for enhancing the quality and efficiency of palliative care services.
This visual guide breaks down important metrics across four categories: Patient-Centered Metrics, Care Efficiency Metrics, Quality of Life Metrics, and Staff Metrics. Each section is designed to help healthcare professionals monitor and improve care delivery for patients facing serious illnesses. Understand how to implement these metrics in your palliative care practices for better outcomes and higher satisfaction levels.
Health Education on prevention of hypertensionRadhika kulvi
Hypertension is a chronic condition of concern due to its role in the causation of coronary heart diseases. Hypertension is a worldwide epidemic and important risk factor for coronary artery disease, stroke and renal diseases. Blood pressure is the force exerted by the blood against the walls of the blood vessels and is sufficient to maintain tissue perfusion during activity and rest. Hypertension is sustained elevation of BP. In adults, HTN exists when systolic blood pressure is equal to or greater than 140mmHg or diastolic BP is equal to or greater than 90mmHg. The
How many patients does case series should have In comparison to case reports.pdfpubrica101
Pubrica’s team of researchers and writers create scientific and medical research articles, which may be important resources for authors and practitioners. Pubrica medical writers assist you in creating and revising the introduction by alerting the reader to gaps in the chosen study subject. Our professionals understand the order in which the hypothesis topic is followed by the broad subject, the issue, and the backdrop.
https://pubrica.com/academy/case-study-or-series/how-many-patients-does-case-series-should-have-in-comparison-to-case-reports/
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cell
R3 Stem Cells and Kidney Repair: A New Horizon in Nephrology" explores groundbreaking advancements in the use of R3 stem cells for kidney disease treatment. This insightful piece delves into the potential of these cells to regenerate damaged kidney tissue, offering new hope for patients and reshaping the future of nephrology.
The Impact of Meeting: How It Can Change Your Life
04Personalized medicine.pptx
1. Personalized Medicine : Introduction, Definition
& Pharmacogenetics
PRESENTED BY-:
Shweta P. Jadhav
M Pharm 1 St
Year
Dept. Of Pharmaceutics
Government College of Pharmacy, Karad.
2. Introduction
Personalized Medicine is referred as Precision medicine.
It integrates the information about person’s genes, proteins to prevent ,diagnose & treat disease.
It uses the information from patient’s genotype.
The use of patient-specific information & biomarkers to make more informed choices regarding
optimal therapeutic treatment regimen.
3. Need of Personalized Medicine
Variations in people.
Role of these variations in health & disease
Personalized medicine
4. Definition
A medical treatment to the individual characteristics of each patient that not only
improves the ability to diagnose & treat disease ,but offers the potential to detect
disease at an earlier stage & to treat it effectively.
The right drug to the right patient for the right disease at the right time with the right
dosage.
An emerging practice of medicine that uses individual’s genetic profile to guide
decisions made in regard to the prevention diagnosis & treatment of disease.
5. Pharmacogenomics (PGx)-
A branch of pharmacology concerned with using DNA & amino acid and
sequence data to inform drug development and testing.
Application of genomics to study human variability in drug response.
A study of how gene affects the persons response to drug.
Pharmacogenomics
Pharmacology Genomics
6. Pharmacogenomics:
Plays an important role in identifying responders & non-responders to medication
,avoiding adverse effects and optimizing drug dose .
It is the field of study and examines impact of genetic variation and drug
responses via biomarkers.
Personalized medicine utilizes the biomarkers to diagnose disease.
7. Pharmacogenetics
The branch of pharmacology concerned with the effect of genetic factors on
reactions to drugs.
Effect of genetic variation on drug response.
The study or clinical testing of genetic variation that assists in individual patient’s
differentiation response to drug.
Pharmacogenetics
Pharmacology Genetics
10. Candidate- Gene Studies
Goal- Characterize candidate genes and variants related to disease.
Assess the generalizability of family-based observations.
Genes selected based on their functional involvement & genetic variants are
identified and then tested for association with disease.
11. Genome-Wide Association Study (GWAS)
Goal- To identify which region in the genome are associated with disease.
The survey of the role of common genetic variation in disease or drug response .
Done by genotyping large sets of SNPs across the genome.
To determine whether a particular allele or a set of alleles is more common in
patients with a certain disease.
12. Advantages of Pharmacogenetics
Can identify new targets.
Low possibility of ADRs.
Reduced time and cost of drug development.
Pharmacogenetic data can be submitted to FDA.
