Classification of the tumors of the ovary
•Download as PPTX, PDF•
2 likes•186 views
This document discusses the World Health Organization classification of ovarian tumors. It outlines the major categories of epithelial tumors, the most common type of ovarian tumors, comprising 60% of cases. Within epithelial tumors, it describes the histological features and classifications of serous, mucinous, endometrioid, clear cell, Brenner, and seromucinous tumors. It notes that serous and mucinous cystadenomas are the most prevalent epithelial tumors, together accounting for 30% of ovarian cancers. Details are provided on the benign, borderline, and malignant subtypes for each tumor type based on histological appearance.
Report
Share
Report
Share
Recommended
Ovarian tumors I
Ovarian tumors are common in women and account for 3% of cancers in females. The majority (80%) of ovarian tumors are benign. Ovarian tumors are classified based on their histological characteristics. The main classifications include surface epithelial tumors (the most common type), germ cell tumors, and sex cord stromal tumors. Surface epithelial tumors can be further classified as serous, mucinous, endometrioid, clear cell, transitional, and other subtypes. Serous and mucinous tumors account for over half of all ovarian cancers. Serous tumors are more common and malignant forms often spread beyond the ovaries at diagnosis. Mucinous tumors are usually larger, multiloculated cysts containing mucinous fluid
PATHOLOGY OF THE CERVIX
The document discusses pathology of the cervix, including:
1. Benign diseases like inflammations (acute and chronic cervicitis), metaplasias, hyperplasias, and benign tumors like endocervical polyps and leiomyomas.
2. Precancerous lesions like squamous intraepithelial lesions and glandular intraepithelial lesions.
3. Cancerous tumors including invasive carcinomas, mesynchymal tumors, mixed epithelial mesynchymal tumors, and other rare tumor types. Chronic cervicitis is most often caused by sexually transmitted pathogens like Chlamydia trachomatis and Neisseria gonorrhoeae. Squamous metaplasia and other
Leiomyomata uteri
A leiomyoma is a benign smooth muscle tumor that originates in the uterus. They are very common, affecting 20-40% of women during their reproductive years. The most common symptoms are abnormal uterine bleeding, pelvic pressure or pain. Treatment options include observation, medication/hormonal therapy, myomectomy (surgical removal), or hysterectomy depending on the severity of symptoms, size and location of fibroids, and desire for future fertility. Laparoscopic and vaginal approaches for myomectomy have benefits of less pain and faster recovery compared to open abdominal myomectomy.
Ovary slide share 2
This document discusses ovarian tumors, specifically germ cell tumors. It provides information on the classification, histopathology, immunoprofile, and other characteristics of various types of ovarian germ cell tumors including dysgerminoma, yolk sac tumor, embryonal carcinoma, choriocarcinoma, immature teratoma, and mature cystic teratoma. It also mentions other rare subtypes such as struma ovarii. The document aims to provide pathology residents with comprehensive information on diagnosing and classifying these tumor types.
germ cell tumours of ovary
This document provides information about germ cell tumors of the ovary. It begins by defining germ cells and explaining that germ cell tumors are composed of different histological types derived from primordial germ cells. It then discusses the basis of germ cell tumors and provides details about specific tumor types like dysgerminoma and endodermal sinus tumor. Dysgerminoma is described as the most common malignant germ cell tumor, often occurring in younger women. Its histological features, diagnosis, and high chemosensitivity and radiosensitivity are summarized. Endodermal sinus tumor is outlined as the third most common malignant germ cell tumor characterized by elevated AFP levels.
uterus pathological lesions
1) Uterine tumors include endometrial polyps, hyperplasia, and carcinomas. Endometrial hyperplasia is classified based on complexity and presence of atypia, with complex hyperplasia with atypia carrying the highest risk of developing into carcinoma.
2) Endometrial carcinomas are classified into Type I (endometrioid) and Type II (non-endometrioid). Type I carcinomas are associated with estrogen excess and hyperplasia, while Type II carcinomas arise in an atrophic endometrium and have a poorer prognosis.
3) Leiomyomas are the most common benign uterine tumor, while leiomyosarcom
Germ cell tumors of ovary
Presentation about the the second most common type of ovarian tumors which have a very unique property of being similar to the testicular germ cell tumors.
Benign ovarian tumours
This document discusses the diagnosis and management of adnexal masses. It provides information on the normal size and variation of ovaries and lifetime risk of ovarian neoplasms. Differential diagnoses of adnexal masses are outlined based on patient age. Diagnostic evaluation includes physical exam, ultrasound, CT or MRI if needed. Common ovarian tumors at different life stages are described. Functional cysts, endometriomas, benign and borderline tumors are discussed. Complications, clinical presentation, imaging and tumor markers are summarized. Guidelines for management of asymptomatic cysts and indications for surgery are provided.
Recommended
Ovarian tumors I
Ovarian tumors are common in women and account for 3% of cancers in females. The majority (80%) of ovarian tumors are benign. Ovarian tumors are classified based on their histological characteristics. The main classifications include surface epithelial tumors (the most common type), germ cell tumors, and sex cord stromal tumors. Surface epithelial tumors can be further classified as serous, mucinous, endometrioid, clear cell, transitional, and other subtypes. Serous and mucinous tumors account for over half of all ovarian cancers. Serous tumors are more common and malignant forms often spread beyond the ovaries at diagnosis. Mucinous tumors are usually larger, multiloculated cysts containing mucinous fluid
PATHOLOGY OF THE CERVIX
The document discusses pathology of the cervix, including:
1. Benign diseases like inflammations (acute and chronic cervicitis), metaplasias, hyperplasias, and benign tumors like endocervical polyps and leiomyomas.
2. Precancerous lesions like squamous intraepithelial lesions and glandular intraepithelial lesions.
3. Cancerous tumors including invasive carcinomas, mesynchymal tumors, mixed epithelial mesynchymal tumors, and other rare tumor types. Chronic cervicitis is most often caused by sexually transmitted pathogens like Chlamydia trachomatis and Neisseria gonorrhoeae. Squamous metaplasia and other
Leiomyomata uteri
A leiomyoma is a benign smooth muscle tumor that originates in the uterus. They are very common, affecting 20-40% of women during their reproductive years. The most common symptoms are abnormal uterine bleeding, pelvic pressure or pain. Treatment options include observation, medication/hormonal therapy, myomectomy (surgical removal), or hysterectomy depending on the severity of symptoms, size and location of fibroids, and desire for future fertility. Laparoscopic and vaginal approaches for myomectomy have benefits of less pain and faster recovery compared to open abdominal myomectomy.
Ovary slide share 2
This document discusses ovarian tumors, specifically germ cell tumors. It provides information on the classification, histopathology, immunoprofile, and other characteristics of various types of ovarian germ cell tumors including dysgerminoma, yolk sac tumor, embryonal carcinoma, choriocarcinoma, immature teratoma, and mature cystic teratoma. It also mentions other rare subtypes such as struma ovarii. The document aims to provide pathology residents with comprehensive information on diagnosing and classifying these tumor types.
germ cell tumours of ovary
This document provides information about germ cell tumors of the ovary. It begins by defining germ cells and explaining that germ cell tumors are composed of different histological types derived from primordial germ cells. It then discusses the basis of germ cell tumors and provides details about specific tumor types like dysgerminoma and endodermal sinus tumor. Dysgerminoma is described as the most common malignant germ cell tumor, often occurring in younger women. Its histological features, diagnosis, and high chemosensitivity and radiosensitivity are summarized. Endodermal sinus tumor is outlined as the third most common malignant germ cell tumor characterized by elevated AFP levels.
uterus pathological lesions
1) Uterine tumors include endometrial polyps, hyperplasia, and carcinomas. Endometrial hyperplasia is classified based on complexity and presence of atypia, with complex hyperplasia with atypia carrying the highest risk of developing into carcinoma.
2) Endometrial carcinomas are classified into Type I (endometrioid) and Type II (non-endometrioid). Type I carcinomas are associated with estrogen excess and hyperplasia, while Type II carcinomas arise in an atrophic endometrium and have a poorer prognosis.
3) Leiomyomas are the most common benign uterine tumor, while leiomyosarcom
Germ cell tumors of ovary
Presentation about the the second most common type of ovarian tumors which have a very unique property of being similar to the testicular germ cell tumors.
Benign ovarian tumours
This document discusses the diagnosis and management of adnexal masses. It provides information on the normal size and variation of ovaries and lifetime risk of ovarian neoplasms. Differential diagnoses of adnexal masses are outlined based on patient age. Diagnostic evaluation includes physical exam, ultrasound, CT or MRI if needed. Common ovarian tumors at different life stages are described. Functional cysts, endometriomas, benign and borderline tumors are discussed. Complications, clinical presentation, imaging and tumor markers are summarized. Guidelines for management of asymptomatic cysts and indications for surgery are provided.
Renal pediatric tumors
This document discusses renal pediatric tumors. It begins by describing the main types of nephroblastic tumors and renal epithelial tumors of childhood. Wilms tumor, or nephroblastoma, comprises over 80% of renal tumors in children and is discussed in detail, including associated syndromes, gross and microscopic pathology, staging, and treatment. Mesoblastic nephroma and clear cell sarcoma are also described as relatively rare but important renal tumors of childhood. The key information provided includes classification, clinical features, histopathology, immunoprofile, differential diagnosis, and prognosis for the major pediatric renal tumors.
FIGO Endometrium Staging 2023.pptx
This document outlines the 2023 FIGO staging system for endometrial cancer. It discusses the different histological subtypes and their prognostic implications. The staging system is stratified by tumor extent, including involvement of the myometrium, cervix, ovaries, lymph nodes, and distant metastasis. Molecular classification is also recommended to further stratify prognosis within stages. The 2023 system aims to better incorporate histology, lymphovascular space invasion, and molecular features to predict patient outcomes.
Placental pathology
This document provides information about placental pathology. It describes the structure, development, functions and examination of the placenta. It discusses various anomalies and non-neoplastic lesions seen in placenta such as twin pregnancy, succenturiate lobes, membranacea and infarcts. It also covers tumors and tumor-like conditions including chorioangioma and gestational trophoblastic disease. Complete hydatidiform mole is described as a condition caused by abnormal gametogenesis resulting in trophoblastic hyperplasia and cistern formation.
Ovarian classification and Management
1. Ovarian tumors can be functional cysts, benign neoplasms, or malignant neoplasms. Transvaginal ultrasound and tumor markers like CA-125 are used to evaluate adnexal masses and assess risk of malignancy.
2. For postmenopausal women, unilateral cysts under 5 cm with normal CA-125 can be monitored, while larger or complex cysts warrant surgical removal due to higher risk of cancer.
3. Borderline ovarian tumors have characteristics between benign and malignant tumors and are staged similarly to ovarian cancer, with surgery being the main treatment.
Milan cytology reporting
The document discusses the development and benefits of the Milan System for Reporting Salivary Gland Cytopathology. It aims to standardize terminology for salivary gland FNA reports which previously lacked uniformity. The system categorizes specimens as non-diagnostic, non-neoplastic, atypia of undetermined significance, neoplastic (benign or uncertain malignant potential), suspicious for malignancy, or malignant. It is intended to improve communication between pathologists and clinicians, enhance patient care, and facilitate research by allowing standardized data collection across institutions. While validation is ongoing, the system provides a practical framework for uniform reporting of salivary gland cytology.
Testicular tumors
This document provides information on testicular tumors, including:
1. It describes the two major categories of testicular tumors - germ cell tumors (95% of cases) and sex cord-stromal tumors. Germ cell tumors are aggressive cancers capable of rapid dissemination but most can now be cured.
2. It covers the various types of germ cell tumors - seminoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma - discussing their characteristics, risk factors, pathogenesis, morphology, and microscopy.
3. Seminoma is the most common germ cell tumor, occurring most often in the third decade. Embryonal carcinoma is more
Renal cell carcinoma for students
Renal cell carcinoma (RCC) arises from the renal tubular epithelium. It is more common in males aged 60-80. Risk factors include chronic renal failure and von Hippel-Lindau disease. The main types are clear cell carcinoma (70-80%), papillary carcinoma (10-15%) and chromophobe renal carcinoma (5%). Symptoms include hematuria, flank pain, and an abdominal mass. Treatment is usually nephrectomy or partial nephrectomy to remove the tumor.
High Grade Papillary Serous Cystadenocarcinoma of Bilateral Ovaries with Caps...
High Grade Papillary Serous Cystadenocarcinoma of Bilateral Ovaries with Caps...Dr. Varughese George
This document contains an academic review of a patient case involving a 51-year-old woman with abdominal pain and distention, decreased urine output, and weight loss. Clinical findings revealed a mass in the right iliac region. Radiological findings from ultrasound and CT scan showed cystic masses in both ovaries suspicious for malignancy. The patient underwent staging laparotomy and chemotherapy. Pathological examination of surgical specimens found high grade papillary serous cystadenocarcinoma of both ovaries with tumor deposits in the omentum and one fallopian tube. Ovarian cyst fluid was also positive for malignant cells. The case report discusses the histopathological findings and staging of ovarian cancer.Non neoplastic disorders of endometrium
This document discusses non-neoplastic disorders of the endometrium. It describes acute and chronic endometritis, adenomyosis, and endometriosis. For adenomyosis, it notes that it refers to growth of endometrial tissue into the myometrium, which can cause menorrhagia and pelvic pain. For endometriosis, it discusses the three theories of histogenesis and lists common locations including the ovaries. It also summarizes abnormal uterine bleeding and its causes including dysfunctional uterine bleeding from anovulation or an inadequate luteal phase.
Pap Smear: A Bird's Eye View from a Cytopathologist
The document provides information about Pap smear tests, including:
1. A Pap smear is a screening test to detect precancerous and cancerous lesions of the cervix in order to treat them and reduce cervical cancer rates. New guidelines recommend screening starting at age 21 or within 3 years of becoming sexually active.
2. Screening intervals are yearly until age 30, then every 3 years. Screening can end after age 70, or after hysterectomy with 3 normal previous Pap smears.
3. Limitations include low sensitivity and potential for false negatives due to sampling, fixation, or interpretation errors. Proper sampling of the transformation zone is important for detection of early cancers.
Approach to testicular tumors
This document provides an overview of approaches to testicular tumors. It discusses updates to classifications including changing ITGCN to GCNIS. A new classification system is presented that divides tumors into GCT derived from GCNIS, GCT unrelated to GCNIS, sex cord stromal tumors, and other rare tumors. Factors like age, medical history, tumor site, and gross appearance can provide clues before histological examination. Histological patterns including cells with pale cytoplasm, glandular/tubular patterns, microcystic patterns, and oxyphilic cells can indicate tumor types.
Cancer of the Vulva
Vulvar cancer accounts for about 5% of cancers of the female genital system in the US. Possible signs include bleeding, itching, lumps or growths on the vulva, skin color changes, or ulcers. Risk factors include HPV infection, smoking, and precancerous skin conditions. Treatment depends on stage but may involve surgery to remove the tumor and nearby lymph nodes, radiation therapy, or chemoradiation. Side effects can include skin irritation in the vulvar area, as well as urinary and bowel issues. Overall survival rates vary from over 80% for local stage to under 20% for distant stage disease.
Ovaries and Ovarian Tumours
The document provides information on normal ovaries and ovarian masses. It discusses:
1. The typical size of normal ovaries and factors that can affect size.
2. Risks of ovarian neoplasms - a woman has a 5-10% lifetime risk of surgery for a suspected ovarian mass, of which 13-21% will be malignant.
3. Differential diagnosis of adnexal masses varies with age, with masses in pre-menarchal/post-menopausal women considered highly abnormal.
UTERINE LEIOMYOSARCOMA
This document summarizes information about uterine sarcomas, with a focus on leiomyosarcomas and endometrial stromal sarcomas. It discusses the clinical presentation, diagnostic challenges, classification, staging, prognostic factors, surgical management, and adjuvant therapies for these rare but aggressive uterine cancers. Key points include the difficulty of pre-operative diagnosis, the importance of surgical staging and cytoreduction, and the limited but emerging role of adjuvant therapies like radiation and chemotherapy.
Soft tissue tumor
This document discusses soft tissue tumors. It defines soft tissue and describes its composition. It notes that soft tissue tumors can be caused by radiation, burns, trauma, viruses, or genetic syndromes. The document outlines various tumor types including liposarcomas, fibrosarcomas, and malignant fibrous histiocytomas. It describes histologic patterns seen in different tumors and discusses grading systems. Pseudosarcomas like nodular fasciitis are also summarized.
Histopathology of Pilonidal Sinus
This is a presentation about the pathology of pilonidal sinus, covering its pathophysiology, histology, and the development of secondary carcinoma.
Malignant ovarian tumors
This document provides an overview of malignant ovarian tumors. It discusses the epidemiology, risk factors, pathogenesis, classification, and management of ovarian cancers. Some key points include:
- Ovarian cancer has a high mortality rate and accounts for over 50% of gynecological cancer deaths.
- Risk factors include nulliparity, family history, and hereditary conditions like BRCA mutations.
- Theories for pathogenesis include incessant ovulation and retrograde menstruation.
- The majority are epithelial tumors, most commonly serous carcinomas. Other types include mucinous, endometrioid, clear cell, and germ cell tumors.
- Early stages are often asymptomatic, contributing to late
Pap smear Examination
This document summarizes the Pap smear examination results of a 39-year-old HIV-positive female patient. On initial examination, the patient was found to have an inflammatory smear with a high nuclear-to-cytoplasmic ratio and irregular, hyperchromatic nuclei. This was assessed as atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (ASC-H). On follow up, a syncytial cluster was seen with similar abnormal cellular features, leading to a diagnosis of high-grade squamous intraepithelial lesion (HSIL). A cervical biopsy confirmed carcinoma in situ of the cervix. The document discusses the criteria used to make these assessments and differentiate HSIL from
Pathology of Uterine corpus. Dr. Sufia Husain, 2018
This document provides an overview of uterine corpus pathology including endometrial hyperplasia, endometrial carcinoma, and leiomyomas (fibroids).
It discusses the causes, classification, clinical features and behavior of endometrial hyperplasia. It also covers the two main types of endometrial carcinoma, their risk factors, genetics, morphology and prognosis.
Fibroids are described as the most common benign tumor of the female genital tract. Their clinical presentation, locations within the uterus, gross and microscopic appearance are outlined. Rarely, fibroids can undergo malignant transformation to leiomyosarcoma.
Pathology of Endometrial cancer 2022.pptx
This is a concise presentation on the pathology of endometrial cancer based on the latest WHO female genital tumors latest edition, 5th edition
prepared on April 2022
Pancreatic tumours
This document summarizes various types of pancreatic tumours. It describes pancreatic ductal adenocarcinoma as the most common exocrine pancreatic cancer, accounting for 85% of cases. Risk factors and clinical features are provided. Other exocrine tumours discussed include acinar cell carcinoma, cystic pancreatic neoplasms such as microcystic cystadenoma and mucinous cystadenoma. Neuroendocrine tumours such as insulinomas are also summarized. Rare tumour types like anaplastic carcinoma, giant cell tumour and intraductal papillary mucinous neoplasms are described.
Anal carcinoma
This document discusses anal canal carcinoma, including:
1. The anatomy and histology of the anal canal, which can give rise to different tumor types based on location.
2. The staging and classification of anal canal carcinoma according to the TNM and American Joint Committee on Cancer systems.
3. Risk factors for anal canal carcinoma like HPV infection and HIV status, as well as pre-cancerous lesions.
4. Methods for diagnosing anal canal carcinoma through physical examination, imaging like MRI, and biopsy.
More Related Content
What's hot
Renal pediatric tumors
This document discusses renal pediatric tumors. It begins by describing the main types of nephroblastic tumors and renal epithelial tumors of childhood. Wilms tumor, or nephroblastoma, comprises over 80% of renal tumors in children and is discussed in detail, including associated syndromes, gross and microscopic pathology, staging, and treatment. Mesoblastic nephroma and clear cell sarcoma are also described as relatively rare but important renal tumors of childhood. The key information provided includes classification, clinical features, histopathology, immunoprofile, differential diagnosis, and prognosis for the major pediatric renal tumors.
FIGO Endometrium Staging 2023.pptx
This document outlines the 2023 FIGO staging system for endometrial cancer. It discusses the different histological subtypes and their prognostic implications. The staging system is stratified by tumor extent, including involvement of the myometrium, cervix, ovaries, lymph nodes, and distant metastasis. Molecular classification is also recommended to further stratify prognosis within stages. The 2023 system aims to better incorporate histology, lymphovascular space invasion, and molecular features to predict patient outcomes.
Placental pathology
This document provides information about placental pathology. It describes the structure, development, functions and examination of the placenta. It discusses various anomalies and non-neoplastic lesions seen in placenta such as twin pregnancy, succenturiate lobes, membranacea and infarcts. It also covers tumors and tumor-like conditions including chorioangioma and gestational trophoblastic disease. Complete hydatidiform mole is described as a condition caused by abnormal gametogenesis resulting in trophoblastic hyperplasia and cistern formation.
Ovarian classification and Management
1. Ovarian tumors can be functional cysts, benign neoplasms, or malignant neoplasms. Transvaginal ultrasound and tumor markers like CA-125 are used to evaluate adnexal masses and assess risk of malignancy.
2. For postmenopausal women, unilateral cysts under 5 cm with normal CA-125 can be monitored, while larger or complex cysts warrant surgical removal due to higher risk of cancer.
3. Borderline ovarian tumors have characteristics between benign and malignant tumors and are staged similarly to ovarian cancer, with surgery being the main treatment.
Milan cytology reporting
The document discusses the development and benefits of the Milan System for Reporting Salivary Gland Cytopathology. It aims to standardize terminology for salivary gland FNA reports which previously lacked uniformity. The system categorizes specimens as non-diagnostic, non-neoplastic, atypia of undetermined significance, neoplastic (benign or uncertain malignant potential), suspicious for malignancy, or malignant. It is intended to improve communication between pathologists and clinicians, enhance patient care, and facilitate research by allowing standardized data collection across institutions. While validation is ongoing, the system provides a practical framework for uniform reporting of salivary gland cytology.
Testicular tumors
This document provides information on testicular tumors, including:
1. It describes the two major categories of testicular tumors - germ cell tumors (95% of cases) and sex cord-stromal tumors. Germ cell tumors are aggressive cancers capable of rapid dissemination but most can now be cured.
2. It covers the various types of germ cell tumors - seminoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma - discussing their characteristics, risk factors, pathogenesis, morphology, and microscopy.
3. Seminoma is the most common germ cell tumor, occurring most often in the third decade. Embryonal carcinoma is more
Renal cell carcinoma for students
Renal cell carcinoma (RCC) arises from the renal tubular epithelium. It is more common in males aged 60-80. Risk factors include chronic renal failure and von Hippel-Lindau disease. The main types are clear cell carcinoma (70-80%), papillary carcinoma (10-15%) and chromophobe renal carcinoma (5%). Symptoms include hematuria, flank pain, and an abdominal mass. Treatment is usually nephrectomy or partial nephrectomy to remove the tumor.
High Grade Papillary Serous Cystadenocarcinoma of Bilateral Ovaries with Caps...
High Grade Papillary Serous Cystadenocarcinoma of Bilateral Ovaries with Caps...Dr. Varughese George
This document contains an academic review of a patient case involving a 51-year-old woman with abdominal pain and distention, decreased urine output, and weight loss. Clinical findings revealed a mass in the right iliac region. Radiological findings from ultrasound and CT scan showed cystic masses in both ovaries suspicious for malignancy. The patient underwent staging laparotomy and chemotherapy. Pathological examination of surgical specimens found high grade papillary serous cystadenocarcinoma of both ovaries with tumor deposits in the omentum and one fallopian tube. Ovarian cyst fluid was also positive for malignant cells. The case report discusses the histopathological findings and staging of ovarian cancer.Non neoplastic disorders of endometrium
This document discusses non-neoplastic disorders of the endometrium. It describes acute and chronic endometritis, adenomyosis, and endometriosis. For adenomyosis, it notes that it refers to growth of endometrial tissue into the myometrium, which can cause menorrhagia and pelvic pain. For endometriosis, it discusses the three theories of histogenesis and lists common locations including the ovaries. It also summarizes abnormal uterine bleeding and its causes including dysfunctional uterine bleeding from anovulation or an inadequate luteal phase.
Pap Smear: A Bird's Eye View from a Cytopathologist
The document provides information about Pap smear tests, including:
1. A Pap smear is a screening test to detect precancerous and cancerous lesions of the cervix in order to treat them and reduce cervical cancer rates. New guidelines recommend screening starting at age 21 or within 3 years of becoming sexually active.
2. Screening intervals are yearly until age 30, then every 3 years. Screening can end after age 70, or after hysterectomy with 3 normal previous Pap smears.
3. Limitations include low sensitivity and potential for false negatives due to sampling, fixation, or interpretation errors. Proper sampling of the transformation zone is important for detection of early cancers.
Approach to testicular tumors
This document provides an overview of approaches to testicular tumors. It discusses updates to classifications including changing ITGCN to GCNIS. A new classification system is presented that divides tumors into GCT derived from GCNIS, GCT unrelated to GCNIS, sex cord stromal tumors, and other rare tumors. Factors like age, medical history, tumor site, and gross appearance can provide clues before histological examination. Histological patterns including cells with pale cytoplasm, glandular/tubular patterns, microcystic patterns, and oxyphilic cells can indicate tumor types.
Cancer of the Vulva
Vulvar cancer accounts for about 5% of cancers of the female genital system in the US. Possible signs include bleeding, itching, lumps or growths on the vulva, skin color changes, or ulcers. Risk factors include HPV infection, smoking, and precancerous skin conditions. Treatment depends on stage but may involve surgery to remove the tumor and nearby lymph nodes, radiation therapy, or chemoradiation. Side effects can include skin irritation in the vulvar area, as well as urinary and bowel issues. Overall survival rates vary from over 80% for local stage to under 20% for distant stage disease.
Ovaries and Ovarian Tumours
The document provides information on normal ovaries and ovarian masses. It discusses:
1. The typical size of normal ovaries and factors that can affect size.
2. Risks of ovarian neoplasms - a woman has a 5-10% lifetime risk of surgery for a suspected ovarian mass, of which 13-21% will be malignant.
3. Differential diagnosis of adnexal masses varies with age, with masses in pre-menarchal/post-menopausal women considered highly abnormal.
UTERINE LEIOMYOSARCOMA
This document summarizes information about uterine sarcomas, with a focus on leiomyosarcomas and endometrial stromal sarcomas. It discusses the clinical presentation, diagnostic challenges, classification, staging, prognostic factors, surgical management, and adjuvant therapies for these rare but aggressive uterine cancers. Key points include the difficulty of pre-operative diagnosis, the importance of surgical staging and cytoreduction, and the limited but emerging role of adjuvant therapies like radiation and chemotherapy.
Soft tissue tumor
This document discusses soft tissue tumors. It defines soft tissue and describes its composition. It notes that soft tissue tumors can be caused by radiation, burns, trauma, viruses, or genetic syndromes. The document outlines various tumor types including liposarcomas, fibrosarcomas, and malignant fibrous histiocytomas. It describes histologic patterns seen in different tumors and discusses grading systems. Pseudosarcomas like nodular fasciitis are also summarized.
Histopathology of Pilonidal Sinus
This is a presentation about the pathology of pilonidal sinus, covering its pathophysiology, histology, and the development of secondary carcinoma.
Malignant ovarian tumors
This document provides an overview of malignant ovarian tumors. It discusses the epidemiology, risk factors, pathogenesis, classification, and management of ovarian cancers. Some key points include:
- Ovarian cancer has a high mortality rate and accounts for over 50% of gynecological cancer deaths.
- Risk factors include nulliparity, family history, and hereditary conditions like BRCA mutations.
- Theories for pathogenesis include incessant ovulation and retrograde menstruation.
- The majority are epithelial tumors, most commonly serous carcinomas. Other types include mucinous, endometrioid, clear cell, and germ cell tumors.
- Early stages are often asymptomatic, contributing to late
Pap smear Examination
This document summarizes the Pap smear examination results of a 39-year-old HIV-positive female patient. On initial examination, the patient was found to have an inflammatory smear with a high nuclear-to-cytoplasmic ratio and irregular, hyperchromatic nuclei. This was assessed as atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (ASC-H). On follow up, a syncytial cluster was seen with similar abnormal cellular features, leading to a diagnosis of high-grade squamous intraepithelial lesion (HSIL). A cervical biopsy confirmed carcinoma in situ of the cervix. The document discusses the criteria used to make these assessments and differentiate HSIL from
Pathology of Uterine corpus. Dr. Sufia Husain, 2018
This document provides an overview of uterine corpus pathology including endometrial hyperplasia, endometrial carcinoma, and leiomyomas (fibroids).
It discusses the causes, classification, clinical features and behavior of endometrial hyperplasia. It also covers the two main types of endometrial carcinoma, their risk factors, genetics, morphology and prognosis.
Fibroids are described as the most common benign tumor of the female genital tract. Their clinical presentation, locations within the uterus, gross and microscopic appearance are outlined. Rarely, fibroids can undergo malignant transformation to leiomyosarcoma.
Pathology of Endometrial cancer 2022.pptx
This is a concise presentation on the pathology of endometrial cancer based on the latest WHO female genital tumors latest edition, 5th edition
prepared on April 2022
What's hot (20)
High Grade Papillary Serous Cystadenocarcinoma of Bilateral Ovaries with Caps...
High Grade Papillary Serous Cystadenocarcinoma of Bilateral Ovaries with Caps...
Pap Smear: A Bird's Eye View from a Cytopathologist
Pap Smear: A Bird's Eye View from a Cytopathologist
Pathology of Uterine corpus. Dr. Sufia Husain, 2018
Pathology of Uterine corpus. Dr. Sufia Husain, 2018
Similar to Classification of the tumors of the ovary
Pancreatic tumours
This document summarizes various types of pancreatic tumours. It describes pancreatic ductal adenocarcinoma as the most common exocrine pancreatic cancer, accounting for 85% of cases. Risk factors and clinical features are provided. Other exocrine tumours discussed include acinar cell carcinoma, cystic pancreatic neoplasms such as microcystic cystadenoma and mucinous cystadenoma. Neuroendocrine tumours such as insulinomas are also summarized. Rare tumour types like anaplastic carcinoma, giant cell tumour and intraductal papillary mucinous neoplasms are described.
Anal carcinoma
This document discusses anal canal carcinoma, including:
1. The anatomy and histology of the anal canal, which can give rise to different tumor types based on location.
2. The staging and classification of anal canal carcinoma according to the TNM and American Joint Committee on Cancer systems.
3. Risk factors for anal canal carcinoma like HPV infection and HIV status, as well as pre-cancerous lesions.
4. Methods for diagnosing anal canal carcinoma through physical examination, imaging like MRI, and biopsy.
Ovarian tumour
1. The document describes the main types of ovarian tumours, which are epithelial tumours and germ cell tumours.
2. Epithelial tumours include serous cystadenoma (the most common), mucinous cystadenoma, Brenner tumour, endometrioid tumour, and clear cell tumour. They can spread transcoelomically, lymphatically or hematogenously.
3. Germ cell tumours include teratoma (the most common), dysgerminoma, endodermal sinus tumour, choriocarcinoma, and embryonal carcinoma. Teratomas can be mature, immature, or monodermal.
Tumors of salivary gland
This document provides information on various types of salivary gland tumors. It begins with an overview of the major and minor salivary gland tumors that are most commonly seen in adults and children. Examples include Warthin tumor, acinic cell carcinoma, and polymorphous low-grade adenocarcinoma. The document then describes the histological features of many benign and malignant epithelial and nonepithelial salivary gland tumors at both the macroscopic and microscopic levels. Key diagnostic characteristics of tumors like pleomorphic adenoma, myoepithelioma, oncocytoma, and adenoid cystic carcinoma are highlighted.
Neoplasia
This document provides an overview of neoplasia (new growths), including definitions, classifications, and key terminology. It defines a neoplasm as abnormal tissue growth that is uncoordinated and persists after stimuli cease. Neoplasms are classified as either benign or malignant. Benign neoplasms are non-invasive and do not spread, while malignant neoplasms invade surrounding tissues and can metastasize. The document discusses characteristics, examples, and histological features of different types of benign and malignant neoplasms of epithelial and mesenchymal origin. Key concepts covered include tumor components, nomenclature, gross and microscopic morphology, and other related pathological terms.
Lect.2. salivary gland pathology
The document discusses salivary gland diseases, focusing on sialadenitis (inflammation of the salivary glands) and salivary gland tumors. Sialadenitis can be caused by viruses, bacteria, or autoimmune disorders. The most common viral cause is mumps. Bacterial sialadenitis often results from ductal obstruction. Chronic sialadenitis is usually caused by Sjögren's syndrome. Common benign salivary gland tumors include pleomorphic adenoma, Warthin's tumor, and monomorphic adenomas. Malignant tumors include mucoepidermoid carcinoma and adenoid cystic carcinoma.
Testicular tumors
This document provides information on testicular tumors, including their classification, presentation, histopathology, and immunohistochemistry. It discusses the most common types of germ cell tumors - seminoma, spermatocytic seminoma, embryonal carcinoma, yolk sac tumor, and teratoma. It also covers sex cord stromal tumors such as Leydig cell tumor and Sertoli cell tumor. Key points include that seminoma is the most common germ cell tumor in adults. Embryonal carcinoma and yolk sac tumor often occur as components of mixed germ cell tumors. Teratomas contain mature somatic tissues. Immunohistochemistry aids in distinguishing tumor types.
Dr samreen younas
This document discusses salivary gland tumors. It begins with definitions of tumors and classifications of salivary glands and salivary gland tumors. It then covers the incidence, clinical features, histopathological features, and treatment plans for various benign and malignant salivary gland tumors. The document emphasizes that surgical resection is usually the primary treatment for salivary gland tumors, with adjuvant radiotherapy sometimes used as well.
Testicular tumor imaging
This document provides an overview of imaging in testicular tumors. It begins with the embryology and anatomy of the testes. Ultrasound is described as the primary imaging method for evaluating testicular lesions. MRI may also be used and can help characterize indeterminate lesions. The document reviews the classification, risk factors, clinical manifestations, patterns of spread, staging, and imaging appearances of various testicular tumors including seminoma, mixed germ cell tumors, and others. Imaging plays an important role in detecting tumors, staging disease, and monitoring for recurrence.
Lect.2. salivary gland pathology
Here are the answers to your questions:
1. Common types of salivary gland benign tumors with origin of each:
- Pleomorphic adenoma - originates from the intercalated duct cells and myoepithelial cells.
- Oncocytic tumors - originate from the striated duct cells.
- Acinous cell tumors - originate from the acinar cells.
- Mucoepidermoid tumors and squamous cell carcinomas develop in the excretory duct cells.
2. The histological features of mucoepidermoid carcinoma include:
- Containing mucin-producing cells and epithelial cells of the epidermoid variety.
- Divided into
Presentation dr rahul seminar (2)[1387]
This document discusses the role of fine needle aspiration cytology (FNAC) in evaluating salivary gland neoplasms. It begins with an introduction noting that salivary gland FNAs present challenges due to the wide range of possible lesions. It then covers normal salivary gland morphology, indications and contraindications for FNAC, advantages, technical considerations, complications, and classification of salivary gland lesions according to the WHO. Specific benign and malignant lesions are discussed in detail, including characteristics on cytology and differential diagnoses. Imaging is also shown demonstrating features of various lesions. In summary, the document provides a comprehensive overview of utilizing FNAC to evaluate salivary gland masses.
Tumors of lung seminar dr. swarupa
Tumors of lung with its 2015 WHO classification along with cytological evidences to rule out various differential diagnosis. The difference between small biopsy and resected specimen terminology has been briefed in a precise manner.
gynaecology.Ovarian tumours.(dr.salama)
This document provides a classification and overview of ovarian cysts and tumours. It discusses the different types of cysts including physiological cysts such as follicular and luteal cysts. It also covers the different types of primary ovarian neoplasms including epithelial tumours, sex cord stromal tumours, and germ cell tumours. For each type, it describes the histological features, clinical presentation, diagnosis, and management. Overall, the document serves as a comprehensive reference for the various ovarian cysts and tumours that healthcare providers may encounter.
Diseases of the ovary
This document provides an overview of diseases of the ovary, including both non-neoplastic and neoplastic lesions. It discusses common non-neoplastic conditions like follicular cysts and polycystic ovarian disease. It also covers the various types of ovarian tumors, including surface epithelial tumors (serous, mucinous, endometrioid), germ cell tumors, and sex cord-stromal tumors. For each type, it describes the gross and microscopic appearance as well as examples of histopathology slides. Metastatic tumors to the ovaries are also briefly discussed.
Salivary gland tumors classification
The document provides information on the classification of salivary gland tumors. It begins with an introduction and then discusses the etiology, histogenesis, theories of histogenesis, morphogenesis, genetics, WHO classification from 1972-2017, general features of benign and malignant tumors, problems in clinical diagnosis, investigations including imaging techniques and histopathological investigation. It also provides examples of common tumors like pleomorphic adenoma and adenoid cystic carcinoma. Finally, it briefly outlines the TNM staging system for salivary gland tumors.
Neoplasia basics ! first lecture !
This document provides an overview of neoplasia (abnormal tissue growth) including definitions, classifications, characteristics of benign and malignant tumors, and methods of tumor diagnosis and analysis. It discusses the differences between benign and malignant tumors, how tumors are named and graded, common routes of cancer spread, and uses histopathology to analyze biopsied tumor samples.
An approach to diagonosis of soft tissue sarcoma.pptx
This document provides an overview of the histological diagnosis of soft tissue tumors. It discusses the World Health Organization classification of soft tissue tumors and covers the major tumor types. It describes the clinical information and morphological features that are important to evaluate. The role of immunohistochemistry is emphasized for determining the cell lineage and making an accurate diagnosis. Novel immunohistochemical markers that are helpful for specific tumor types are also reviewed. The document concludes with a discussion of tumors of uncertain origin that may require immunohistochemistry for diagnosis.
OVARIAN TUMOURS
1. The document discusses various types of ovarian tumours, including benign, borderline, and malignant surface epithelial tumours as well as germ cell tumours and sex cord-stromal tumours.
2. Etiological factors for ovarian tumours include nulliparity, heredity such as BRCA gene mutations, and genetic syndromes like Lynch syndrome.
3. Common epithelial tumours include serous and mucinous tumours. Germ cell tumours include mature teratomas, dysgerminomas, and choriocarcinomas. Sex cord-stromal tumours include granulosa cell tumours and thecomas.
Neoplasia: Nomenclature, Staging and Grading
This document provides definitions and outlines the nomenclature and characteristics of benign and malignant tumors. It defines neoplasia as new abnormal growth and discusses how tumors are named based on the tissue of origin. Benign tumors are well-differentiated, slow growing, and remain localized, while malignant tumors are poorly differentiated, grow rapidly, can invade locally and metastasize to other sites. The document compares features of benign versus malignant tumors such as differentiation, growth rate, local invasion and metastasis.
FEMALE GENITAL TRACT: OVARIAN TUMOURS
- Ovarian tumours can be benign or malignant and arise from the surface epithelium, germ cells, or sex cord-stromal tissues.
- Risk factors for ovarian cancer include nulliparity, hereditary factors like BRCA gene mutations, and genetic syndromes.
- The most common ovarian tumours are serous and mucinous cystadenomas, which usually present as abdominal masses.
- Malignant ovarian tumours often spread before diagnosis. Metastatic tumours to the ovaries are also possible.
Similar to Classification of the tumors of the ovary (20)
An approach to diagonosis of soft tissue sarcoma.pptx
An approach to diagonosis of soft tissue sarcoma.pptx
Recently uploaded
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.10 Benefits an EPCR Software should Bring to EMS Organizations
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
SENSORY NEEDS B.SC. NURSING SEMESTER II.
Sensation is the neurological process by which we become aware of surrounding environment.
Nano-gold for Cancer Therapy chemistry investigatory project
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
Acute Gout Care & Urate Lowering Therapy .pdf
In this document , the management of acute gout attacks and a description of urate lowering therapy is mentioned.
Pharmacology of 5-hydroxytryptamine and Antagonist
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
LOW BIRTH WEIGHT. PRETERM BABIES OR SMALL FOR DATES BABIES
low birth weight presentation. Low birth weight (LBW) infant is defined as the one whose birth weight is less than 2500g irrespective of their gestational age. Premature birth and low birth weight(LBW) is still a serious problem in newborn. Causing high morbidity and mortality rate worldwide. The nursing care provide to low birth weight babies is crucial in promoting their overall health and development. Through careful assessment, diagnosis,, planning, and evaluation plays a vital role in ensuring these vulnerable infants receive the specialize care they need. In India every third of the infant weight less than 2500g.
Birth period, socioeconomical status, nutritional and intrauterine environment are the factors influencing low birth weight
Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
What are the different types of Dental implants.
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
How to Control Your Asthma Tips by gokuldas hospital.
Respiratory issues like asthma are the most sensitive issue that is affecting millions worldwide. It hampers the daily activities leaving the body tired and breathless.
The key to a good grip on asthma is proper knowledge and management strategies. Understanding the patient-specific symptoms and carving out an effective treatment likewise is the best way to keep asthma under control.
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
This quiz was conducted as a promotional event for the 2024 Annual Meet of Kerala Chapter of API.
More than 20 participants took part everyday !
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Do you have abnormal smell after periods? It may be vaginitis. Do not worry, herbal medicine Fuyan Pill can help you get a cure.
vonoprazan A novel drug for GERD presentation
Vonoprazan, a new potassium acid channel blocker used in the conditions of GERD and gastric ulcer, duodenal ulcer ....
NARCOTICS- POLICY AND PROCEDURES FOR ITS USE
This document outlines policies and procedures for handling narcotic and controlled drugs in NABH accredited hospitals.
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
Fallopian tube blockage may cause female infertility. For treatment, herbal medicine Fuyan Pill can be a solution.
Lecture 6 -- Memory 2015.pptlearning occurs when a stimulus (unconditioned st...
learning occurs when a stimulus (unconditioned stimulus) eliciting a response (unconditioned response) • is paired with another stimulus (conditioned stimulus)
Recently uploaded (20)
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
10 Benefits an EPCR Software should Bring to EMS Organizations
10 Benefits an EPCR Software should Bring to EMS Organizations
Nano-gold for Cancer Therapy chemistry investigatory project
Nano-gold for Cancer Therapy chemistry investigatory project
Pharmacology of 5-hydroxytryptamine and Antagonist
Pharmacology of 5-hydroxytryptamine and Antagonist
LOW BIRTH WEIGHT. PRETERM BABIES OR SMALL FOR DATES BABIES
LOW BIRTH WEIGHT. PRETERM BABIES OR SMALL FOR DATES BABIES
How to Control Your Asthma Tips by gokuldas hospital.
How to Control Your Asthma Tips by gokuldas hospital.
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
Lecture 6 -- Memory 2015.pptlearning occurs when a stimulus (unconditioned st...
Lecture 6 -- Memory 2015.pptlearning occurs when a stimulus (unconditioned st...
Classification of the tumors of the ovary
- 1. DR NANDAKANTA MAHANTA PGT, DEPARTMENT OF PATHOLOGY SMCH, SILCHAR
- 3. EPITHELIAL TUMORS MESENCHYMAL TUMORS MIXED EPITHELIAL AND MESENCHYMAL TUMORS SEX CORD-STROMAL TUMORS MIXED SEX CORD-STROMAL TUMORS GERM CELL TUMORS MONOCLONAL TERATOMA AND SOMATIC TYPE TUMORS ARISING FROM A DERMOID CYST GERM CELL-SEX CORD-STROMAL TUMORS MISCELLANEOUS TUMORS MESOTHELIAL TUMORS SOFT TISSUE TUMORS TUMOR LIKE LESIONS LYMPHOID AND MYELOID TUMORS SECONDARY TUMORS
- 4. EPITHELIAL TUMORS MOST COMMON 6O % OF OVARIAN TUMORS SEROUS AND MUCINOUS CYSTADENOMAS ARE MOST COMMON EPITHELIAL TUMORS (30% )
- 5. EPITHELIAL TUMORS a)SEROUS TUMORS: FIG: SEROUS CYSTADENOMA, LINED BY CILIATED LOW COLUMNAR CELL WITH BLAND BASAL NUCLEI BENIGN: Interior and exterior surface smooth. Serous cystadenoma Serous adenofibroma (solid) Serous surface papilloma
- 6. a)SEROUS TUMORS BORDERLINE: large,usually multilocular cystic neoplasms that are bilateral in 35 -40% cases Serous borderline tumour/ Atypical proliferative serous tumour Serous borderline tumour-micropapillary variant / Non invasive low-grade serous carcinoma
- 8. a)SEROUS TUMORS Serous carcinoma. The tumor cells cover papillae and grow in sheets. They have large vesicular nuclei with coarse chromatin, and some have prominent nucleoli. MALIGNANT: mixture of cystic, papillary, and solid growth. Low-grade serous carcinoma High-grade serous carcinoma
- 9. b)MUCINOUS TUMORS BENIGN: U/L, 10 cm,uni/multilocular mucin filled cysts Mucinous cystadenoma (cystic) Mucinous adenofi broma (solid) BORDERLINE: Mucinous borderline tumour / Atypical proliferative mucinous tumour MALIGNANT: large, multilocular cystic ,15 -20 cm.Firm, fleshy, white or tan solid areas, foci of hemorrhage Or necrosis Malignant Mucinous carcinoma
- 10. MUCINOUS TUMOR MUCINOUS CYSTADENOMA BORDERLINE MUCINOUS TUMOR
- 12. c)ENDOMETRIOID TUMORS BENIGN: solid fibrous tumor, Endometriotic cyst Endometrioid cystadenoma Endometrioid adenofibroma BORDERLINE: Endometrioid borderline tumour / Atypical proliferative endometrioid tumour MALIGNANT: cystic and solid / completely solid Endometrioid carcinoma
- 13. ENDOMETROID TUMOR Endometrioid adenofibroma. Glands lined by a single layer of benign endometrial-type cells grow in dense fibrous stroma. Borderline endometrioid tumor, glandular pattern seen
- 15. d)CLEAR CELL TUMORS BENIGN: Clear cell cystadenoma Clear cell adenofibroma BORDERLINE: Clear cell borderline tumour / Atypical proliferative clear cell tumour MALIGNANT: >90% Clear cell carcinoma
- 16. CLEAR CELL TUMOR CLEAR CELL ADENOFIBROMA: cuboidal to low columnar cell, hobnail nuclei CLEAR CELL CARCINOMA: cuboidal to columnar tumor cell, nuclei are pleomorphic
- 17. e)BRENNER TUMORS: a type of adenofibroma in which nests of transitional epithelium grow in a fibrous stroma. solid fibrous tumor BENIGN: Brenner tumour BORDERLINE: Borderline Brenner tumour / Atypical proliferative Brenner tumour MALIGNANT: Malignant Brenner tumour
- 18. BRENNER TUMOR BENIGN BRENNER TUMOR BORDERLINE BRENNER TUMOR
- 19. MALIGNANT BRENNER TUMOR:when a benign or proliferating Brenner tumor is found adjacent to transitional cell carcinoma, the tumor is designated as a malignant Brenner tumor.
- 20. f)SEROMUCINOUS TUMORS BENIGN: Seromucinous cystadenoma Seromucinous adenofibroma BORDERLINE: Seromucinous borderline tumour / Atypical proliferative seromucinous tumour MALIGNANT: Seromucinous carcinoma