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CEREBRUM
BY
M.HIMASAILA
Assistant professor
Sri Padmavathi School of Pharmacy
CENTRAL NERVOUS SYSTEM
Cerebrum
 Largest part of the forebrain.
 Divided into two halves, the
(cerebral hemipheres),
which are separated by a
deep median longitudinal
fissure which lodges the falx
cerebri.
 In the depth of the fissure,
the hemispheres are
connected by a bundle of
fibers called the corpus
callosum.
Median longitudinal fissure
Corpus callosum
Right
hemisphere
Left
hemisphere
Superolateral Medial
Inferior (tentorial)
Surfaces
 Cerebral cortex: Superficial layer of
grey matter
 White matter (WM): Deeper to the
cortex, contain axons to and from
the cells of the cortex
 Basal ganglia: Number of nuclear
masses buried within the white
matter
 Lateral ventricle: The cavity of
hemisphere
Cortex Basal
ganglia
WM
WM
Lateral
ventricle
Structure of Cerebrum
Lobes of Cerebrum
The superficial layer of grey matter is highly convoluted to form a complex
pattern of ridges (gyri) and grooves (sulci). This arrangement maximizes the
surface area of the cerebral cortex (about 70% is hidden within the depths of sulci).
S g
• Three sulci, consistent in
position, named central, lateral
(sylvian) & parieto-occipital,
divide each hemisphere into
FOUR lobes: Frontal, Parietal,
Temporal & Occipital (named
after overlying bones)
Functionally each hemisphere
contains a ‘limbic lobe’ on the
medial surface.
motor function,
motivation,
aggression,
smell and mood
emotions,
memory storage
& Linking
conscious
intellectual
functions with
the unconscious
autonomic
functions,
smell, hearing,
memory and
abstract thought
visual processing
reception and
evaluation of
sensory
information
Function of Lobes
 Frontal lobe:
 Precentral gyrus.
 Superior & inferior
frontal sulci divide the
lobe into superior,
middle & inferior
frontal gyri.
Superior , middle &
inferior frontal gyri
Precentral
gyrus
Superior
parietal lobule
Inferior
parietal
lobule
Postcentral
gyrus
Intraparietal
sulcus
sfs
ifs
 Parietal lobe:
 Postcentral gyrus.
 Intraparietal sulcus divide the lobe
into superior & inferior parietal
lobules.
 Temporal lobe:
 Superior & inferior
temporal sulci giving rise
to superior, middle &
inferior temporal gyri.
 Insula: the gyrus in the
depth of lateral fissure,
covered by parts of
frontal, parietal &
temporal lobes called the
opercula (removed in
lower picture.).
Superior, middle &
inferior temporal gyri
insula
sts
its
Medial Surface
 Sulci: Parietooccipital, Calcarine, Cingulate
 Gyri: Cingulate, Parahippocampal
• Brodmann produced a
numbered, cytological
map of cerebral cortex
based upon its regional
histological characteristics
• Subdivisions with similar
cellular and laminar
structure are called
'areas'
• Brodmann's numbering of
these cortical locations
has become one of the
standard ways to identify
brain areas.
Brodmann’s Map
Functional Areas
of the
Cerebral Cortex
Frontal Lobe
Primary motor cortex: Located in
precentral gyrus (Brodmann area
4).
Premotor cortex: Located in the
region immediately anterior to the
precentral gyrus (Brodmann’s area 6).
Frontal eye field: Located in the middle frontal gyrus immediately
in front of motor cortex (Brodmann’s area 8).
Broca’s (motor
speech) area: Located
in the inferior frontal
gyrus of the dominant
hemisphere, usually left
(Brodmann’s area 44
& 45).
Prefrontal cortex:
Extensive region of the
frontal lobe anterior to
premotor area.
Parietal lobe
Primary visual cortex: located on
the medial surface of the
hemisphere, in the gyri
surrounding the calcarine sulcus
(Brodmann’s area 17).
Occipital lobe
Visual association cortex: located
around the primary visual cortex.
Parietal association cortex:
located posterior to primary
somatosensory cortex.
Primary somatosensory cortex:
located in postcentral gyrus
(Brodmann’s area 1, 2, 3).
Temporal Lobe
Auditory association cortex: located
immediately around the primary
auditory cortex (also includes
Wernick’s area)
Parahippocampal gyrus:
located in the inferomedial
part of temporal lobe. Deep to
this gyrus lies the
hippocampus and the
amygdala, which are parts of
limbic system
Primary auditory cortex: located in
the superior surface of the superior
temporal gyrus (Brodmann’s area
41, 42)
Language Area
 Organized around the lateral
fissure.
 Broca’s area: concerned with
expressive aspects of language.
 Wernick’s area: responsible
for comprehension of the
spoken words.
 Nearby regions of temporal
lobe and parietal lobe (angular
gyrus & supramarginal
gyrus of the inferior parietal
lobule) are important in
naming, reading, writing, and
calculation.
White Matter
 Underlies the cortex, contains nerve fibers, neuroglia cells and blood vessels.
 The nerve fibers originate, terminate or sometimes both, within the cortex.
 Depending on their origin & termination, these nerve fibers are classified
into three types: Association, Projection & Commissural
Association fibers: Unite
different parts of the same
hemisphere, are of two types:
long & short
Commissural fibers: Connect the
corresponding regions of the two
hemispheres
Projection fibers: Consist of
afferent and efferent fibers of
the cerebral cortex

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Cerebrum ppt

  • 1. CEREBRUM BY M.HIMASAILA Assistant professor Sri Padmavathi School of Pharmacy CENTRAL NERVOUS SYSTEM
  • 2. Cerebrum  Largest part of the forebrain.  Divided into two halves, the (cerebral hemipheres), which are separated by a deep median longitudinal fissure which lodges the falx cerebri.  In the depth of the fissure, the hemispheres are connected by a bundle of fibers called the corpus callosum. Median longitudinal fissure Corpus callosum Right hemisphere Left hemisphere
  • 4.  Cerebral cortex: Superficial layer of grey matter  White matter (WM): Deeper to the cortex, contain axons to and from the cells of the cortex  Basal ganglia: Number of nuclear masses buried within the white matter  Lateral ventricle: The cavity of hemisphere Cortex Basal ganglia WM WM Lateral ventricle Structure of Cerebrum
  • 5. Lobes of Cerebrum The superficial layer of grey matter is highly convoluted to form a complex pattern of ridges (gyri) and grooves (sulci). This arrangement maximizes the surface area of the cerebral cortex (about 70% is hidden within the depths of sulci). S g • Three sulci, consistent in position, named central, lateral (sylvian) & parieto-occipital, divide each hemisphere into FOUR lobes: Frontal, Parietal, Temporal & Occipital (named after overlying bones) Functionally each hemisphere contains a ‘limbic lobe’ on the medial surface.
  • 6. motor function, motivation, aggression, smell and mood emotions, memory storage & Linking conscious intellectual functions with the unconscious autonomic functions, smell, hearing, memory and abstract thought visual processing reception and evaluation of sensory information Function of Lobes
  • 7.  Frontal lobe:  Precentral gyrus.  Superior & inferior frontal sulci divide the lobe into superior, middle & inferior frontal gyri. Superior , middle & inferior frontal gyri Precentral gyrus Superior parietal lobule Inferior parietal lobule Postcentral gyrus Intraparietal sulcus sfs ifs  Parietal lobe:  Postcentral gyrus.  Intraparietal sulcus divide the lobe into superior & inferior parietal lobules.
  • 8.  Temporal lobe:  Superior & inferior temporal sulci giving rise to superior, middle & inferior temporal gyri.  Insula: the gyrus in the depth of lateral fissure, covered by parts of frontal, parietal & temporal lobes called the opercula (removed in lower picture.). Superior, middle & inferior temporal gyri insula sts its
  • 9. Medial Surface  Sulci: Parietooccipital, Calcarine, Cingulate  Gyri: Cingulate, Parahippocampal
  • 10. • Brodmann produced a numbered, cytological map of cerebral cortex based upon its regional histological characteristics • Subdivisions with similar cellular and laminar structure are called 'areas' • Brodmann's numbering of these cortical locations has become one of the standard ways to identify brain areas. Brodmann’s Map
  • 12. Frontal Lobe Primary motor cortex: Located in precentral gyrus (Brodmann area 4). Premotor cortex: Located in the region immediately anterior to the precentral gyrus (Brodmann’s area 6). Frontal eye field: Located in the middle frontal gyrus immediately in front of motor cortex (Brodmann’s area 8). Broca’s (motor speech) area: Located in the inferior frontal gyrus of the dominant hemisphere, usually left (Brodmann’s area 44 & 45). Prefrontal cortex: Extensive region of the frontal lobe anterior to premotor area.
  • 13. Parietal lobe Primary visual cortex: located on the medial surface of the hemisphere, in the gyri surrounding the calcarine sulcus (Brodmann’s area 17). Occipital lobe Visual association cortex: located around the primary visual cortex. Parietal association cortex: located posterior to primary somatosensory cortex. Primary somatosensory cortex: located in postcentral gyrus (Brodmann’s area 1, 2, 3).
  • 14. Temporal Lobe Auditory association cortex: located immediately around the primary auditory cortex (also includes Wernick’s area) Parahippocampal gyrus: located in the inferomedial part of temporal lobe. Deep to this gyrus lies the hippocampus and the amygdala, which are parts of limbic system Primary auditory cortex: located in the superior surface of the superior temporal gyrus (Brodmann’s area 41, 42)
  • 15.
  • 16. Language Area  Organized around the lateral fissure.  Broca’s area: concerned with expressive aspects of language.  Wernick’s area: responsible for comprehension of the spoken words.  Nearby regions of temporal lobe and parietal lobe (angular gyrus & supramarginal gyrus of the inferior parietal lobule) are important in naming, reading, writing, and calculation.
  • 17. White Matter  Underlies the cortex, contains nerve fibers, neuroglia cells and blood vessels.  The nerve fibers originate, terminate or sometimes both, within the cortex.  Depending on their origin & termination, these nerve fibers are classified into three types: Association, Projection & Commissural Association fibers: Unite different parts of the same hemisphere, are of two types: long & short Commissural fibers: Connect the corresponding regions of the two hemispheres Projection fibers: Consist of afferent and efferent fibers of the cerebral cortex