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The Cell Membrane
The Key to Cellular Transport
Characteristics of the Cell
Membrane
   Made of phospholipids
    – arranged in two layers called a bilayer
   Selectively permeable
    -it controls “selects” what can enter or leave the cell
    -some materials are allowed through others aren’t
   Fluid Mosaic Model
    - made of different molecules – phospholipids, proteins,
       cholesterol
    - the molecules aren’t static but can move “fluid”
Lipid bi-layer – the heart of the
             membrane
   Phospholipids are arranged into 2 layers

    - called a bilayer
Phospholipids: Phosphate Heads
   Polar/hydrophillic – attracted to water and
    charged particles
Phospholipids: Lipid Tails
   Nonpolar/hydrophobic – repel water and
    charged particles
Cholesterol
   Found in bilayer – helps to hold the membrane together
    while adding to fluidity of the membrane
Glycoproteins
   Proteins with carbohydrates attached – identifies the cell
    type
     -allows it to bind with other cells of the same type
Receptor Proteins
   recognize and bind with substances outside of the cell,
    causing changes inside the cell
Enzymes
   Allow reactions to occur- light reactions and ETS occur
    with enzymes in membrane
Transport Proteins
   Proteins that extend across the membrane – provide a
    way for large or charged molecules to cross the
    membrane
Types of Transport Proteins
   Ion Channels- allow certain charged particles to cross
    the membrane – passive transport

   Carrier Proteins – bind to a specific molecule and carry it
    across the membrane
      - facilitated diffusion – proteins carry molecules with
    the concentration gradient /no cellular energy is
    required

      - active transport – proteins carry molecules against
    the concentration gradient/ cellular energy is required

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Structure and function of cell membrane

  • 1. The Cell Membrane The Key to Cellular Transport
  • 2. Characteristics of the Cell Membrane  Made of phospholipids – arranged in two layers called a bilayer  Selectively permeable -it controls “selects” what can enter or leave the cell -some materials are allowed through others aren’t  Fluid Mosaic Model - made of different molecules – phospholipids, proteins, cholesterol - the molecules aren’t static but can move “fluid”
  • 3. Lipid bi-layer – the heart of the membrane  Phospholipids are arranged into 2 layers - called a bilayer
  • 4. Phospholipids: Phosphate Heads  Polar/hydrophillic – attracted to water and charged particles
  • 5. Phospholipids: Lipid Tails  Nonpolar/hydrophobic – repel water and charged particles
  • 6. Cholesterol  Found in bilayer – helps to hold the membrane together while adding to fluidity of the membrane
  • 7. Glycoproteins  Proteins with carbohydrates attached – identifies the cell type -allows it to bind with other cells of the same type
  • 8. Receptor Proteins  recognize and bind with substances outside of the cell, causing changes inside the cell
  • 9. Enzymes  Allow reactions to occur- light reactions and ETS occur with enzymes in membrane
  • 10. Transport Proteins  Proteins that extend across the membrane – provide a way for large or charged molecules to cross the membrane
  • 11. Types of Transport Proteins  Ion Channels- allow certain charged particles to cross the membrane – passive transport  Carrier Proteins – bind to a specific molecule and carry it across the membrane - facilitated diffusion – proteins carry molecules with the concentration gradient /no cellular energy is required - active transport – proteins carry molecules against the concentration gradient/ cellular energy is required

Editor's Notes

  1. Amount of cholesterol varies depending on the amount of fluidity needed in a membrane. Ranges from 25% of total lipid to 0%
  2. The carbohydrates are oligosaccharides (chains of no more 15 monosaccharides) Glycoproteins also are responsible for cell adhesion. Two cells with matching glycoproteins will bind together – allows the creation of tissues. Glycolipids exist as well they serve as recognition signals for cell interactions. The carbohydrate of glycolipids in cancer cells change. This signals to white blood cells that the cell needs to be destroyed