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Membrane Transport
How molecules move through cell
membranes
• Where can you find membranes in a cell?
• What are the functions of the cell
membrane?
• What is a semipermeable membrane?
Membranes are found
around the cell and each organelle
• The cell boundary;
separates cellular
materials from
external environment
• Regulates which
materials can enter
and exit the cell
• Maintains
homeostasis in cell
Semipermeable membranes
• Membranes that allow certain materials to
pass through based on certain properties
– size
– hydrophobicity
– charge
The Fluid Mosaic Model: The membrane is
made up of many smaller parts and the
structure moves like a fluid
• http://www.susanahalpine.com/anim/Life/memb.htm
Phospholipids and proteins make up most of the
membrane. Cholesterol helps with flexibility, and
carbohydrate chains help communicate with other
cells
A phospholipid is a type of lipid that has
2 fatty acid tails and a phosphate head.
• http://telstar.ote.cmu.edu/Hughes/tuto
rial/cellmembranes/
The phosphate head is
hydrophilic
because it is attracted to
water
The fatty acid tails are
hydrophobic
Because they are repelled
by water
Use E-Life animation 6.3
https://www.youtube.com/watch?v=pzpZdijj
qX8
The phospholipid bilayer forms because the
inside and outside of the cell are mostly water:
A cell membrane has many properties
in common with bubbles!
Clean up:
• Pour soap down drain
• Rinse plate, straw frame and beaker
VERY well
• Throw out used straws and thread ring
• Return plate, straw frame and beaker
• Wipe down table top VERY well
The phospholipid bilayer is a
semipermeable membrane because it
only allows certain molecules to cross.
Hydrophilic, polar, large and charged
molecules must use a Transport Protein to
enter/exit the cell.
The proteins are specific; glucose can only
pass through a glucose transport protein.
There are two types of Transport Proteins:
Protein Channels: a special entryway for
large, polar, hydrophilic and charged ions to
diffuse through the cell membrane
This is called Facilitated Diffusion.
Protein Pumps: we’ll talk about these later
The Big Idea
1. Name 4 components of the cell membrane
2. What kind of molecules CAN go through the
phospholipid bilayer?
3. What kinds of molecules CANNOT go through the
phospholipid bilayer?
4. What is facilitated diffusion?
5. Can any molecule go through any protein channel?
6. When will the molecules stop noticeably moving?
Describe a person
who is passive.
Describe a person
who is active.
Passive Transport:
> Materials move down
the concentration gradient
from high to low solution
concentrations
> Equilibrium is reached
(concentrations are equal
all around)
> No energy (ATP) is
needed by the cell to
move the materials
Active Transport:
1. Materials move up the
concentration gradient,
from low to high solution
concentrations
2. Concentrations
become unbalanced on
either side of the
membrane
3. Energy (ATP) is
needed by the cell to
move the materials
Diffusion
Facilitated
Diffusion
Osmosis
1. Passive
Transport
Protein
Pumps
Endocytosis
Exocytosis
2. Active
Transport
There are two ways that materials can
move in/out of the cell
1. Protein Pumps use energy (ATP,
electrons) to increase the concentration on
one side of the membrane
The Sodium-Potassium (Na+/K+) Pump
uses ATP to move Na+ out and K+ into
nerve, muscle and many other cells.
Protein pumps are found cooperating with
protein channels in
photosynthesis and cell respiration
2. Endocytosis: Materials enter the cell without
crossing the membrane—the membrane folds
around the particles and forms a new vacuole
inside the cell
Amoeba and white blood cells engulf large
food particles through phagocytosis (a type
of endocytosis).
http://www.youtube.com/watch?v=pvOz4V
699gk (mute: annoying soundtrack)
Paramecium Feeding
http://www.youtube.com/watch?v=sn3MTYNe8mM
3. Exocytosis: Vesicles fuse to the cell
membrane to release their contents (cell products
or waste)
Phospholipids from vesicle membranes
integrate into the plasma membrane
Exocytosis in Paramecium
http://www.youtube.com/watch?v=U9pvm_4-bHg
1. What materials can diffuse through the
lipid bilayer without the aid of a protein?
2. What is the difference between facilitated
diffusion and the use of a protein pump?
3. What are the major differences between
Passive Transport and Active Transport?
4. Explain why an animal cell bursts when
placed in a hypotonic solution.

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Plasma type membrane.ppt

  • 1. Membrane Transport How molecules move through cell membranes
  • 2. • Where can you find membranes in a cell? • What are the functions of the cell membrane? • What is a semipermeable membrane?
  • 3. Membranes are found around the cell and each organelle
  • 4.
  • 5. • The cell boundary; separates cellular materials from external environment • Regulates which materials can enter and exit the cell • Maintains homeostasis in cell
  • 6. Semipermeable membranes • Membranes that allow certain materials to pass through based on certain properties – size – hydrophobicity – charge
  • 7. The Fluid Mosaic Model: The membrane is made up of many smaller parts and the structure moves like a fluid • http://www.susanahalpine.com/anim/Life/memb.htm
  • 8. Phospholipids and proteins make up most of the membrane. Cholesterol helps with flexibility, and carbohydrate chains help communicate with other cells
  • 9. A phospholipid is a type of lipid that has 2 fatty acid tails and a phosphate head. • http://telstar.ote.cmu.edu/Hughes/tuto rial/cellmembranes/ The phosphate head is hydrophilic because it is attracted to water The fatty acid tails are hydrophobic Because they are repelled by water Use E-Life animation 6.3 https://www.youtube.com/watch?v=pzpZdijj qX8
  • 10. The phospholipid bilayer forms because the inside and outside of the cell are mostly water:
  • 11. A cell membrane has many properties in common with bubbles!
  • 12. Clean up: • Pour soap down drain • Rinse plate, straw frame and beaker VERY well • Throw out used straws and thread ring • Return plate, straw frame and beaker • Wipe down table top VERY well
  • 13. The phospholipid bilayer is a semipermeable membrane because it only allows certain molecules to cross.
  • 14. Hydrophilic, polar, large and charged molecules must use a Transport Protein to enter/exit the cell. The proteins are specific; glucose can only pass through a glucose transport protein.
  • 15. There are two types of Transport Proteins: Protein Channels: a special entryway for large, polar, hydrophilic and charged ions to diffuse through the cell membrane This is called Facilitated Diffusion. Protein Pumps: we’ll talk about these later
  • 16. The Big Idea 1. Name 4 components of the cell membrane 2. What kind of molecules CAN go through the phospholipid bilayer? 3. What kinds of molecules CANNOT go through the phospholipid bilayer? 4. What is facilitated diffusion? 5. Can any molecule go through any protein channel? 6. When will the molecules stop noticeably moving?
  • 17. Describe a person who is passive. Describe a person who is active.
  • 18. Passive Transport: > Materials move down the concentration gradient from high to low solution concentrations > Equilibrium is reached (concentrations are equal all around) > No energy (ATP) is needed by the cell to move the materials
  • 19. Active Transport: 1. Materials move up the concentration gradient, from low to high solution concentrations 2. Concentrations become unbalanced on either side of the membrane 3. Energy (ATP) is needed by the cell to move the materials
  • 21. 1. Protein Pumps use energy (ATP, electrons) to increase the concentration on one side of the membrane
  • 22. The Sodium-Potassium (Na+/K+) Pump uses ATP to move Na+ out and K+ into nerve, muscle and many other cells.
  • 23. Protein pumps are found cooperating with protein channels in photosynthesis and cell respiration
  • 24. 2. Endocytosis: Materials enter the cell without crossing the membrane—the membrane folds around the particles and forms a new vacuole inside the cell
  • 25. Amoeba and white blood cells engulf large food particles through phagocytosis (a type of endocytosis). http://www.youtube.com/watch?v=pvOz4V 699gk (mute: annoying soundtrack)
  • 27. 3. Exocytosis: Vesicles fuse to the cell membrane to release their contents (cell products or waste)
  • 28. Phospholipids from vesicle membranes integrate into the plasma membrane
  • 30. 1. What materials can diffuse through the lipid bilayer without the aid of a protein? 2. What is the difference between facilitated diffusion and the use of a protein pump? 3. What are the major differences between Passive Transport and Active Transport? 4. Explain why an animal cell bursts when placed in a hypotonic solution.