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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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BRONCHIAL TREE
Histology of respiratory system for medical
students
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Primary
Secondary
Tertiary
Histology of respiratory system for medical
students
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BRONCHIAL TREE
• 1, 2, 3 Bronchi
• Cartilage plates, glands present, smallest is
5mm, many lymphocytes present
• Bronchioles
• No cartilage, no glands
• Alveolar Duct
• Alveolar Sac
• Gas exchange
• Alveolus
Histology of respiratory system for medical
students
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HISTOLOGY OF
BRONCHIAL TREE
• Cartilage
• Rings, plates, disappears
Smooth Muscle Layer
Begins in bronchi,
more prominent in bronchioles
then disappears
• Epithelium
• Pseudostratified, Simple columnar, cuboidal,
squamous
Histology of respiratory system for medical
students
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Bronchus
Histology of respiratory system for medical
students
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Cartilage
Bronchus
Histology of respiratory system for medical
students
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Lamina propria
Bronchus
Histology of respiratory system for medical
students
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Bronchioles
• > 5mm diameter
• No cartilage or glands in mucosa
• Epithelium changes from
• pseudostratified to cuboidal epithelium.
• shortening along the way.
• Only scattered goblet cells initially.
• Clara cells secrete protective proteins.
• Lamina propria contains only
• smooth muscle and elastic fibers.
• Vagus nerve, sympathetic neurons
Histology of respiratory system for medical
students
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Bronchiole x10
Histology of respiratory system for medical
students
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Bronchiole x40
Histology of respiratory system for medical
students
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Alveolus
Bronchiole
Histology of respiratory system for medical
students
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Location of Gas Exchange
Histology of respiratory system for medical
students
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ALVEOLUS AND CAPILLARY
Histology of respiratory system for medical
students
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GAS EXCHANGE
• Respiratory membrane
• Layers
• Cells present in alveolus
• Simple squamous epithelium
• Other cells in alveolus
• Macrophages
• Surfactant cells
Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Section of a terminal bronchiole with
a small portion of a respiratory bronchiole
continuous with an alveolar duct and many alveoli. Low magnification.
Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Diagram of a
portion of the
bronchial tree.
Note that the
smooth muscle in
the alveolar duct
disappears in the
alveoli. (Redrawn
from Baltisberger.)
Histology of respiratory system for medical
students
30
Transition of a terminal bronchiole into
an alveolar duct (arrow). Note
the Clara cells arrowheads.
Respiratory Duct
With Alveoli
Histology of respiratory system for medical
students
31
Alveolus
Histology of respiratory system for medical
students
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Alveolar Sac
Histology of respiratory system for medical
students
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Blood Vessel in Lung
Histology of respiratory system for medical
students
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Alveolus with Capillary
Histology of respiratory system for medical
students
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Interface
between
capillary
and alveolus
Histology of respiratory system for medical
students
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Interface Between Capillary, Alveolus
Histology of respiratory system for medical
students
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Alveoli and interalveolar septum
showing capillaries and epithelial
. Cells type I and II
Histology of respiratory system for medical
students
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Cells Located in Alveolus
• Type I alveolar cells
• Simple squamous cells
• Type II cells
• Surfactant
• Macrophages (dust cells)
Histology of respiratory system for medical
students
39

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histology of respiratory system upper lower