how the respiratory system works:
Inhalation: You breathe in air through your nose or mouth. The air passes through the nasal cavity, where it is warmed, humidified, and filtered. It then travels down the pharynx and into the larynx.
Gas exchange: The air travels down the trachea and into the bronchi, which branch off into smaller and smaller airways called bronchioles. These eventually lead to the alveoli, tiny sacs in the lungs where gas exchange takes place. Oxygen diffuses from the alveoli into the bloodstream, while carbon dioxide diffuses from the bloodstream into the alveoli.
Exhalation: You breathe out air through your nose or mouth. The air travels back up the airways and out of the body.
15. BRONCHIAL TREE
• 1, 2, 3 Bronchi
• Cartilage plates, glands present, smallest is
5mm, many lymphocytes present
• Bronchioles
• No cartilage, no glands
• Alveolar Duct
• Alveolar Sac
• Gas exchange
• Alveolus
Histology of respiratory system for medical
students
15
16. HISTOLOGY OF
BRONCHIAL TREE
• Cartilage
• Rings, plates, disappears
Smooth Muscle Layer
Begins in bronchi,
more prominent in bronchioles
then disappears
• Epithelium
• Pseudostratified, Simple columnar, cuboidal,
squamous
Histology of respiratory system for medical
students
16
20. Bronchioles
• > 5mm diameter
• No cartilage or glands in mucosa
• Epithelium changes from
• pseudostratified to cuboidal epithelium.
• shortening along the way.
• Only scattered goblet cells initially.
• Clara cells secrete protective proteins.
• Lamina propria contains only
• smooth muscle and elastic fibers.
• Vagus nerve, sympathetic neurons
Histology of respiratory system for medical
students
20
26. GAS EXCHANGE
• Respiratory membrane
• Layers
• Cells present in alveolus
• Simple squamous epithelium
• Other cells in alveolus
• Macrophages
• Surfactant cells
Histology of respiratory system for medical
students
26
27. Histology of respiratory system for medical
students
27
Section of a terminal bronchiole with
a small portion of a respiratory bronchiole
continuous with an alveolar duct and many alveoli. Low magnification.
29. Histology of respiratory system for medical
students
29
Diagram of a
portion of the
bronchial tree.
Note that the
smooth muscle in
the alveolar duct
disappears in the
alveoli. (Redrawn
from Baltisberger.)
30. Histology of respiratory system for medical
students
30
Transition of a terminal bronchiole into
an alveolar duct (arrow). Note
the Clara cells arrowheads.
38. Alveoli and interalveolar septum
showing capillaries and epithelial
. Cells type I and II
Histology of respiratory system for medical
students
38
39. Cells Located in Alveolus
• Type I alveolar cells
• Simple squamous cells
• Type II cells
• Surfactant
• Macrophages (dust cells)
Histology of respiratory system for medical
students
39