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Histology of respiratory system for medical
students
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Histology of respiratory system for medical
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Histology of respiratory system for medical
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Histology of respiratory system for medical
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Histology of respiratory system for medical
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Histology of respiratory system for medical
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Histology of respiratory system for medical
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BRONCHIAL TREE
Histology of respiratory system for medical
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Primary
Secondary
Tertiary
Histology of respiratory system for medical
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BRONCHIAL TREE
• 1, 2, 3 Bronchi
• Cartilage plates, glands present, smallest is
5mm, many lymphocytes present
• Bronchioles
• No cartilage, no glands
• Alveolar Duct
• Alveolar Sac
• Gas exchange
• Alveolus
Histology of respiratory system for medical
students
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HISTOLOGY OF
BRONCHIAL TREE
• Cartilage
• Rings, plates, disappears
Smooth Muscle Layer
Begins in bronchi,
more prominent in bronchioles
then disappears
• Epithelium
• Pseudostratified, Simple columnar, cuboidal,
squamous
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Bronchus
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Cartilage
Bronchus
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Lamina propria
Bronchus
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Bronchioles
• > 5mm diameter
• No cartilage or glands in mucosa
• Epithelium changes from
• pseudostratified to cuboidal epithelium.
• shortening along the way.
• Only scattered goblet cells initially.
• Clara cells secrete protective proteins.
• Lamina propria contains only
• smooth muscle and elastic fibers.
• Vagus nerve, sympathetic neurons
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Bronchiole x10
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Bronchiole x40
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Alveolus
Bronchiole
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Location of Gas Exchange
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ALVEOLUS AND CAPILLARY
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GAS EXCHANGE
• Respiratory membrane
• Layers
• Cells present in alveolus
• Simple squamous epithelium
• Other cells in alveolus
• Macrophages
• Surfactant cells
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Histology of respiratory system for medical
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Section of a terminal bronchiole with
a small portion of a respiratory bronchiole
continuous with an alveolar duct and many alveoli. Low magnification.
Histology of respiratory system for medical
students
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Histology of respiratory system for medical
students
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Diagram of a
portion of the
bronchial tree.
Note that the
smooth muscle in
the alveolar duct
disappears in the
alveoli. (Redrawn
from Baltisberger.)
Histology of respiratory system for medical
students
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Transition of a terminal bronchiole into
an alveolar duct (arrow). Note
the Clara cells arrowheads.
Respiratory Duct
With Alveoli
Histology of respiratory system for medical
students
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Alveolus
Histology of respiratory system for medical
students
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Alveolar Sac
Histology of respiratory system for medical
students
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Blood Vessel in Lung
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Alveolus with Capillary
Histology of respiratory system for medical
students
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Interface
between
capillary
and alveolus
Histology of respiratory system for medical
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Interface Between Capillary, Alveolus
Histology of respiratory system for medical
students
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Alveoli and interalveolar septum
showing capillaries and epithelial
. Cells type I and II
Histology of respiratory system for medical
students
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Cells Located in Alveolus
• Type I alveolar cells
• Simple squamous cells
• Type II cells
• Surfactant
• Macrophages (dust cells)
Histology of respiratory system for medical
students
39

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histology of respiratory system upper lower