Best practices to fund, develop and commercialize evidence-based innovation


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In this session we discussed key lessons learned for scientists and start-ups to successfully bring to market evidence-based innovative solutions. We will also present non-dilutive funding opportunities and commercialization resources offered through the US small business research programs. A scientist and inventor turned serial entrepreneur will wrap-up the day sharing insights from his previous venture–funded by the NIMH and sold to McKesson–and his current strategy and vision.
--Chair: Dr. Alison Fenney, Executive Director of the Neurotechnology Industry Organization
--Dr. Margaret Grabb, SBIR/STTR Program Director at the National Institute of Mental Health (NIMH)
--Dr. Rex Jakobovits, Founder of Vivalog Technologies and Experiad

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Best practices to fund, develop and commercialize evidence-based innovation

  1. 1. Best practices to fund, develop and commercialize evidence-based innovation
  2. 2. Best practices to fund, develop and commercialize evidence-based innovation Chaired by: Dr. Alison Fenney, Executive Director, Neurotechnology Industry Organization Dr. Margaret Grabb, SBIR/STTR Program Director, National Institute of Mental Health Dr. Rex Jakobovits, Founder, Vivalog Technologies and Experiad
  3. 3. Small Business Research Programs at NIMH Margaret C. Grabb, Ph.D. SBIR/STTR Program Director December 7, 2016
  4. 4. SBIR/STTR Program Overview 4
  5. 5. SBIR/STTR Program- 3 Phases 5
  6. 6. SBIR/STTR Program- 3 Phases 6
  7. 7. SBIR/STTR Program- 3 Phases 7
  8. 8. SBIR/STTR Program- 3 Phases 8
  9. 9. Commercialization Readiness Pilot (CRP) 9
  10. 10. Technical Assistance Programs NIH Provides Contract Services to Help Small Businesses with Commercialization • Phase I awardees: • Niche Assessment Program: market analysis reports • I-Corp Program: 8 week program with business expert instructors in technology domain • Commercialization Assistance Program: • Phase II awardees:  For emerging and seasoned companies  Business, strategic planning  Training workshops, individual mentoring and consulting sessions
  11. 11. NIH SBIR/STTR Budgets 11 • Phase I guidelines: $150,000; 6 months (SBIR), 1 year (STTR) • Phase I cap: $225,000; 2 years • Phase II guidelines: $1 Million; 2 years • Phase II cap: $1.5 Million; 3 years • Budget waiver If topic is approved as a budget waiver topic (Appendix A of Grant topic list), budget requested can be higher than the cap. Contact program staff before submitting the application.
  12. 12. SBIR/STTR Programs at NIMH 12 NIMH mission  to transform the understanding and treatment of mental illnesses through basic and clinical research, paving the way for prevention, recovery and cure. Diversity of Portfolio  From molecular tools to e-health tools  Community served (neuroscience researchers, clinical researchers, clinicians, patients, caregivers) Innovation in Program to Meet Needs of NIMH  Promoting academic-private sector teams  First SBIR Phase IIb opportunity in the federal government developed at NIMH
  13. 13. NIMH SBIR/STTR Programs: Portfolio 13
  14. 14. NIMH SBIR/STTR Programs: Portfolio 14
  15. 15. NIMH SBIR/STTR Programs: IT Health 15
  16. 16. NIMH SBIR/STTR Programs IT Health in Detail • Passive monitoring techniques (i.e. GPS, accelerometer, internet usage) to predict, prevent and provide real time interventions Cogito Corp. • Platforms to train and disseminate evidence-based practices to clinicians to increase knowledge and adherence- Center for Social Innovation • Online interventions using mobile platforms to extend the reach of Interventions- Recovery Record Research, Inc. • Clinician rated computerized assessments, including remote assessments - Telesage, Inc.; Behavioral Imaging Solutions • Biofeedback, using EEG or other CNS measures- Think Now, Inc. • Platforms to measure medication adherence (injectable sensor, chemical sensor and mobile app)- Xhale, Inc.
  17. 17. NIMH SBIR/STTR Programs Please contact me if interested in learning more about the NIMH SBIR/STTR Programs Meg Grabb, NIMH 301-443-3563 NIH SBIR website:
  18. 18. SBIR as Seed Capital: The Journey to Getting Acquired SharpBrains Summit, Dec 7, 2015 Rex Jakobovits, PhD President, Experiad Solutions
  19. 19. $5K $11K
  20. 20. $5K $11K $28K $37K 2004
  21. 21. $5K $11K $28K $37K $55K each
  22. 22. $5K $11K $28K $37K $55K each $280K 2007-08 + 9 more
  23. 23. $5K $11K $28K $37K $55K each $280K + 9 more
  24. 24. Vivalog Acquired
  25. 25. Vivalog Acquired My Last Day, July 2013 Todd Rex Rex Leaves
  26. 26. (but not too much)
  27. 27. McKesson Due Dilly: 897 requests! • “detailed list by customer of committed development projects (contractual or oral)”; • “agreements relating to confidentiality”; • “schedule of all fixed assets and other property”; • “copies of all policies relating to…”
  28. 28. Q&A
  29. 29. Thank you to all Participants!
  30. 30. Sponsors Thank you to all Speakers & Sponsors!
  31. 31. To learn more, visit