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Spleen
 The spleen is the largest organ in the lymphatic system.
 The spleen is located under the ribcage and above the stomach in the left upper quadrant
of the abdomen.
 The spleen is made up of two basic types of tissue, each with different functions:
 White pulp
 Red pulp
 The white pulp is part of the infection-fighting system (immune system). It produces
white blood cells called lymphocytes, which in turn produce antibodies.
 The red pulp filters the blood, removing unwanted material. The red pulp contains other
white blood cells called phagocytes that ingest microorganisms.
 People can live without a spleen (a condition called asplenia).
 Asplenia is loss of splenic function due to
 Absence of the spleen at birth
 Surgical removal of the spleen (splenectomy)
 A disease that affects the spleen
 Absence of the spleen at birth is a rare disorder. Infants with this disorder often also
have a heart defect.
 Splenectomy is surgical removal of the spleen. It can be done in otherwise healthy
people who require splenectomy after a spleen injury or in people with diseases that
cause the spleen to enlarge and therefore require splenectomy.
 People with functional asplenia have a spleen that does not function properly.
Functional asplenia can be due to a variety of diseases. Common causes include sickle
cell disease, celiac disease, and alcoholic liver disease.

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Spleen

  • 1. Spleen  The spleen is the largest organ in the lymphatic system.  The spleen is located under the ribcage and above the stomach in the left upper quadrant of the abdomen.  The spleen is made up of two basic types of tissue, each with different functions:  White pulp  Red pulp  The white pulp is part of the infection-fighting system (immune system). It produces white blood cells called lymphocytes, which in turn produce antibodies.  The red pulp filters the blood, removing unwanted material. The red pulp contains other white blood cells called phagocytes that ingest microorganisms.  People can live without a spleen (a condition called asplenia).  Asplenia is loss of splenic function due to  Absence of the spleen at birth  Surgical removal of the spleen (splenectomy)  A disease that affects the spleen  Absence of the spleen at birth is a rare disorder. Infants with this disorder often also have a heart defect.
  • 2.  Splenectomy is surgical removal of the spleen. It can be done in otherwise healthy people who require splenectomy after a spleen injury or in people with diseases that cause the spleen to enlarge and therefore require splenectomy.  People with functional asplenia have a spleen that does not function properly. Functional asplenia can be due to a variety of diseases. Common causes include sickle cell disease, celiac disease, and alcoholic liver disease.