The document summarizes Gregor Mendel's experiments with pea plants that laid the foundation for the modern understanding of genetics and heredity. It discusses Mendel's observations of inherited traits in pea plants and how this led him to discover the three laws of inheritance: 1) the law of dominance, 2) the law of segregation, and 3) the law of independent assortment. It also explains some of Mendel's experimental methods and variables he controlled that contributed to his success, such as choosing simple and contrasting traits to study. Finally, it provides examples of genetic crosses and inheritance patterns including monohybrid and dihybrid crosses using Punnett squares.
1. A back cross is a cross between an F1 individual and one of its parents. A test cross is specifically a cross between an F1 individual and its homozygous recessive parent.
2. Back crosses and test crosses are important for determining genotypes, obtaining pure lines, and introducing desirable traits through successive crosses.
3. A test cross, unlike a general back cross, will result in a 1:1 ratio of dominant to recessive phenotypes in the F2 generation, allowing determination of genetic constitution.
This document discusses three genetic inheritance patterns: dominance, incomplete dominance, and co-dominance. Dominance occurs when one allele is expressed over the other. In incomplete dominance, the heterozygous phenotype is intermediate between the two homozygous phenotypes. Examples include flowers and hair color. Co-dominance occurs when both alleles are fully expressed in the heterozygote, so the phenotype shows traits of both. Examples given are coat color in horses and cattle, and chestnut and white coat colors producing a palomino horse.
Gregor Mendel was an Austrian monk who experimented with pea plants in the mid-19th century and is considered the father of genetics. Through his experiments crossing thousands of pea plants, he discovered the basic principles of heredity, including dominance, segregation, and independent assortment. His work showed that traits are passed from parents to offspring through discrete units (now known as genes) that can be dominant or recessive.
This document provides an overview of genetics and Gregor Mendel's experiments with pea plants. It summarizes Mendel's work, including that he conducted monohybrid crosses using pea plants with distinct traits like seed shape, color, and size. Through his careful experiments and quantitative analysis, Mendel discovered the laws of inheritance and developed an understanding of dominant and recessive traits. His work laid the foundations for modern genetics although it was not widely recognized until many decades later.
This document discusses polygenic inheritance, which is when multiple genes cumulatively control a phenotypic trait, rather than a single gene following Mendelian ratios. It provides skin color in humans as an example of polygenic inheritance controlled by multiple genes. The document outlines the ratios expected from two or three controlling genes, and shows how skin color ranges from light to dark depending on the number of dominant alleles present, with the most dominant alleles resulting in darker skin.
The document summarizes Mendel's laws of inheritance based on his experiments with pea plants. It discusses Mendel's discovery of the laws of dominance, segregation, and independent assortment through monohybrid and dihybrid crosses. The law of dominance states that one trait will mask the other in hybrid offspring. The law of segregation explains that alleles separate during gamete formation so each gamete contains one allele. The law of independent assortment says that allele pairs assort independently, resulting in multiple allele combinations in offspring. Mendel's laws explained inheritance of traits for the first time.
This document discusses lethal alleles, which are alleles that cause death in an organism. It defines lethal alleles and provides a brief history of their discovery through early studies of coat color inheritance in mice. The document outlines four types of lethal alleles: early onset alleles that cause death early in life, late onset alleles that cause death late in life, conditional alleles that only cause death under certain environmental conditions, and semi-lethal alleles that only kill some individuals, not all. It provides the example of the Y gene in mice, which causes a yellow coat color but is lethal when present in the homozygous dominant state (YY), though not in the heterozygous or recessive states.
Bio 106
Lecture 11 Genes in Populations
A. Population Genetics
B. Gene Frequencies and Equilibrium
1. Gene Frequencies
2. Gene Pool
3. Model System for Population Stability (Hardy – Weinberg Law)
2
cces2015
C. Changes in Gene Frequencies
1. Mutation
2. Selection
2.1 Relative Fitness
2.2 Selections and Variability
2.3 Selection and Mating
3. Systems
4. Migration
5. Genetic Drift
3
cces2015
D. Race and Species Formation
1. The Concept of Races
2. The Concept of Species
2.1 Reproductive Isolating Mechanisms
2.2 Rapid Speciation
1. A back cross is a cross between an F1 individual and one of its parents. A test cross is specifically a cross between an F1 individual and its homozygous recessive parent.
2. Back crosses and test crosses are important for determining genotypes, obtaining pure lines, and introducing desirable traits through successive crosses.
3. A test cross, unlike a general back cross, will result in a 1:1 ratio of dominant to recessive phenotypes in the F2 generation, allowing determination of genetic constitution.
This document discusses three genetic inheritance patterns: dominance, incomplete dominance, and co-dominance. Dominance occurs when one allele is expressed over the other. In incomplete dominance, the heterozygous phenotype is intermediate between the two homozygous phenotypes. Examples include flowers and hair color. Co-dominance occurs when both alleles are fully expressed in the heterozygote, so the phenotype shows traits of both. Examples given are coat color in horses and cattle, and chestnut and white coat colors producing a palomino horse.
Gregor Mendel was an Austrian monk who experimented with pea plants in the mid-19th century and is considered the father of genetics. Through his experiments crossing thousands of pea plants, he discovered the basic principles of heredity, including dominance, segregation, and independent assortment. His work showed that traits are passed from parents to offspring through discrete units (now known as genes) that can be dominant or recessive.
This document provides an overview of genetics and Gregor Mendel's experiments with pea plants. It summarizes Mendel's work, including that he conducted monohybrid crosses using pea plants with distinct traits like seed shape, color, and size. Through his careful experiments and quantitative analysis, Mendel discovered the laws of inheritance and developed an understanding of dominant and recessive traits. His work laid the foundations for modern genetics although it was not widely recognized until many decades later.
This document discusses polygenic inheritance, which is when multiple genes cumulatively control a phenotypic trait, rather than a single gene following Mendelian ratios. It provides skin color in humans as an example of polygenic inheritance controlled by multiple genes. The document outlines the ratios expected from two or three controlling genes, and shows how skin color ranges from light to dark depending on the number of dominant alleles present, with the most dominant alleles resulting in darker skin.
The document summarizes Mendel's laws of inheritance based on his experiments with pea plants. It discusses Mendel's discovery of the laws of dominance, segregation, and independent assortment through monohybrid and dihybrid crosses. The law of dominance states that one trait will mask the other in hybrid offspring. The law of segregation explains that alleles separate during gamete formation so each gamete contains one allele. The law of independent assortment says that allele pairs assort independently, resulting in multiple allele combinations in offspring. Mendel's laws explained inheritance of traits for the first time.
This document discusses lethal alleles, which are alleles that cause death in an organism. It defines lethal alleles and provides a brief history of their discovery through early studies of coat color inheritance in mice. The document outlines four types of lethal alleles: early onset alleles that cause death early in life, late onset alleles that cause death late in life, conditional alleles that only cause death under certain environmental conditions, and semi-lethal alleles that only kill some individuals, not all. It provides the example of the Y gene in mice, which causes a yellow coat color but is lethal when present in the homozygous dominant state (YY), though not in the heterozygous or recessive states.
Bio 106
Lecture 11 Genes in Populations
A. Population Genetics
B. Gene Frequencies and Equilibrium
1. Gene Frequencies
2. Gene Pool
3. Model System for Population Stability (Hardy – Weinberg Law)
2
cces2015
C. Changes in Gene Frequencies
1. Mutation
2. Selection
2.1 Relative Fitness
2.2 Selections and Variability
2.3 Selection and Mating
3. Systems
4. Migration
5. Genetic Drift
3
cces2015
D. Race and Species Formation
1. The Concept of Races
2. The Concept of Species
2.1 Reproductive Isolating Mechanisms
2.2 Rapid Speciation
BIO 106
Lecture 10
Quantitative Inheritance
A. Inheritance of Quantitative Characters
1. Multiple Genes
2. Number of Genes in polygene Systems
3. Regression to the Mean
4. Effects of Dominance and Gene Interactions
5. Effects of Genes in Multiplying Effects
B. Analysis of Quantitative Characteristics
C. Components of Phenotypic Variance
D. Heredity
1. Heritability in the Narrow Sense
2. Heritability in the Broad Sense
This PPT consists of 15 slides only explaining Pleiotropy. This is a phenomenon when one gene controls more than one trait , the traits may be related .Generally one gene's product acts for many reactions and so can affect more than one trait. Examples can be seen in pea Coloured flower and pigmentation in leaf axil, frizzle trait in chicken, fur colour and deafness in cats,Human pleiotropic traits are PKU,Sickle cell Anaemia. HOsyndrome , p53 gene etc
This document presents information about penetrance and expressivity for Sir Faisal Iqbal. It defines penetrance as the percentage of individuals that show expression of a mutant genotype. Expressivity reflects the range of expression of the mutant genotype. An example is given of the eyeless gene in flies, which can result in normal eyes to complete absence of eyes. Penetrance and expressivity are used to study the degree of expression of a trait quantitatively. Phenotypic mutations can occur due to reasons other than genotype, such as genetic background and environmental factors.
This power point presentation is designed to explain deviation of Mendelian dihybrid ratio due to interaction of genes which may be of following types
1.Two gene pairs affecting same character – 9:3:3:1
2.Epistasis, one gene hides effect of other
a) Recessive Epistasis - 9:3:4
b) Dominant epistasis - 12:3:1
3.Complementary genes - 9:7 ( 2 genes responsible for production of a particular phenotype )
4. Duplicate genes – 15:1 ( same effect given by either of two genes )
5. Polymeric gene action - 9:6:1
6. Inhibitory gene action - 13 : 3
Each interaction is typical in itself and ratios obtained are different
This PPT consists of 24 slides explaining Polygenic Inheritance . Some traits are controlled by two or more genes. These traits differ from Mendelian traits and donot show discrete alternative or contrasting forms and show continuous ranges. Examples of such traits are wheat seed colour, plant height, Human skin colour controlled by at least three genes showing many shades of dark and fare, human height, human eye colour etc
Basics of Undergraduate/university fellows
Complementation between two non-allelic genes (C and P) are essential for production
of a particular or special phenotype i.e., complementary factor.
Two genes involved in a specific pathway and their functional products are required
for gene expression, then one recessive allelic pair at either allelic pair would result in
the mutant phenotype.
When Dominant alleles are present together, they complement each other to yield
complementary factor resulting in a special phenotype.
They are called complementary genes.
When either of gene loci have homozygous recessive alleles (i.e., genotypes of ccPP,
ccPp, CCpp, Ccpp and ccpp), they produce identical phenotypes and change F2 ratio
to 9:7.
This theory proposes that hereditary traits are transmitted from one generation to the next through chromosomes and gametes. Gametes contain only one set of chromosomes and fuse during fertilization to restore the paired chromosome condition. Chromosomes are replicated and passed from parents to offspring, behaving in accordance with Mendel's laws of inheritance and explaining the mechanism of inheritance. Sex is determined by sex chromosomes, which can be of the XX-XY, ZZ-ZW, or XX-XO types.
This document discusses Gregor Mendel's laws of inheritance based on his experiments breeding pea plants. It defines key genetic terms and describes Mendel's three laws: 1) The Law of Dominance states that one allele is dominant over the recessive allele. 2) The Law of Segregation states that alleles segregate and pass to offspring independently during gamete formation. 3) The Law of Independent Assortment states that different genes assort independently of one another during gamete formation. Mendel's laws established basic principles of heredity and laid the foundation for genetics.
Inbreeding occurs when related individuals mate and can increase the proportion of homozygosity. This raises the chances that offspring will be affected by recessive or deleterious traits, leading to genetic disorders and conditions. Inbreeding depression can result in smaller litters, lower fertility, and stillborn or deformed offspring in experiments with animals like adders. The inbreeding coefficient is used to measure inbreeding depression based on the expected and observed heterozygosity within a population. While inbreeding can establish desirable traits in livestock, it generally reduces survival and fertility over time.
Gene action and modification of mendelianBruno Mmassy
This document discusses several types of gene action and inheritance patterns, including complete dominance, incomplete dominance, codominance, overdominance, gene interactions, epistasis, pleiotropy, sex-linked genes, penetrance, and essential genes. It provides examples for each type, such as ABO blood groups showing codominance and coat color in mice demonstrating epistasis.
Heritability is the proportion of phenotypic variation caused by genetic factors rather than environmental factors. It can be estimated as broad sense heritability, using total genetic variance, or narrow sense heritability, using only additive genetic variance. High heritability combined with high genetic advance indicates a character is controlled by additive genes and is best improved through selection. Low heritability with low genetic advance means a character is strongly influenced by the environment. Heritability and genetic advance help plant breeders understand the genetic basis of traits and determine the most effective breeding methods.
This document discusses different types of gene interaction:
1. It defines gene interaction as two or more genes affecting the expression of a single character in an organism.
2. It classifies gene interactions into allelic/non-epistatic interactions which follow classical Mendelian ratios, and non-allelic/epistatic interactions where genes on the same or different chromosomes interact.
3. Epistatic genes suppress or mask the expression of other genes, called hypostatic genes. Epistatic gene interactions are further classified into six types based on how the genes influence each other.
This document discusses Mendelian and non-Mendelian inheritance. It provides examples of cytoplasmic inheritance including the inheritance of chloroplast genes in Mirabilis jalapa, where the phenotype is determined by the genotype of the female parent through cytoplasmic/plastid transmission, not the genes in the nucleus. It also discusses inheritance involving cytoplasmic particles like kappa particles in Paramecium, which are transmitted maternally but whose production is controlled by nuclear genes. The key differences between Mendelian and non-Mendelian inheritance are summarized in a table.
Polygenic inheritance involves multiple genes contributing to a trait, as opposed to single-gene inheritance. It can result in continuous variation, where a wide range of phenotypes exist between extremes. Human skin color and wheat seed color are examples of polygenic traits that show continuous variation, with skin color determined by 3-4 genes influencing melanin production and seed color by 3 genes determining red pigment levels.
Epistasis refers to the phenomenon where the effect of one gene is dependent on the presence of other genes. There are different types of epistatic interactions: dominant epistasis occurs when a dominant allele of one gene masks the effect of alleles at another gene locus; recessive epistasis occurs when a recessive allele of one gene hides the effects of alleles at another locus; and duplicate recessive genes, or complementary genes, produce the same phenotype only when both genes have homozygous recessive alleles. Epistasis can modify expected Mendelian ratios from crosses.
This Power Point Presentation is designed to explain Mendel's experiment on hybridization and dihybrid cross which considers inheritance of two traits at a time and to know whether they are inherited independently or are influenced by each other and also about Law of Independent assortment
This document provides an overview of gene epistasis. It defines epistasis as the phenomenon where the effect of one gene is dependent on the presence of another gene. It discusses the different types of epistatic interactions, including dominant and recessive epistasis. As an example, it describes how epistasis influences human hair color through the interaction of genes that control production of eumelanin and pheomelanin. The document emphasizes that epistasis is important for understanding genetic pathways and evolutionary dynamics.
The chromosome theory of inheritance states that chromosomes contain genes and are responsible for Mendel's principles of segregation and independent assortment during meiosis. Thomas Hunt Morgan's experiments with fruit flies led to the discovery of sex linkage, where genes on the X chromosome show different inheritance patterns between males and females. Nettie Stevens' analysis of beetle karyotypes revealed that females have two X chromosomes while males have one X and one Y chromosome, establishing the sex chromosome system. Morgan then used this information to propose X-linked inheritance for white eye color in fruit flies, providing support for the chromosome theory of inheritance.
This document discusses quantitative inheritance, which refers to inheritance of traits that are influenced by multiple genes and the environment. Quantitative traits show continuous variation and are influenced by small effects from many genes. Examples discussed include human height, skin color, and kernel color in wheat. The kernel color experiment of Nilsson-Ehle is used to demonstrate quantitative inheritance. It involved crossing two wheat varieties and analyzing the ratios of kernel color phenotypes in the offspring. For the experiment to work well, the genes influencing color needed to have additive effects and the environment could not impact phenotypes. The experiment helped establish that quantitative traits are influenced by multiple independent gene loci.
This document provides an overview of genetics and key concepts from Gregor Mendel's experiments. It introduces Mendel's work with pea plants, the principles of inheritance he established including dominance, segregation and independent assortment. It explains genetic crosses such as monohybrid and dihybrid through the use of Punnett squares. The document also discusses examples of genetic inheritance patterns in humans including cystic fibrosis and Gaucher disease. It concludes with a brief overview of concepts beyond Mendelian genetics like incomplete dominance.
This document provides an overview of genetics concepts including:
- Gregor Mendel's experiments with pea plants that established the principles of heredity and inheritance patterns
- Key genetics terms like genotype, phenotype, alleles, homozygous, heterozygous
- How Mendel used monohybrid and dihybrid crosses to study single and double trait inheritance through Punnett squares
- His principles of dominance, segregation, and independent assortment
- Examples of genetic inheritance patterns in humans like cystic fibrosis and Gaucher disease
- Exceptions to Mendelian genetics through incomplete dominance seen in snapdragon flower color
BIO 106
Lecture 10
Quantitative Inheritance
A. Inheritance of Quantitative Characters
1. Multiple Genes
2. Number of Genes in polygene Systems
3. Regression to the Mean
4. Effects of Dominance and Gene Interactions
5. Effects of Genes in Multiplying Effects
B. Analysis of Quantitative Characteristics
C. Components of Phenotypic Variance
D. Heredity
1. Heritability in the Narrow Sense
2. Heritability in the Broad Sense
This PPT consists of 15 slides only explaining Pleiotropy. This is a phenomenon when one gene controls more than one trait , the traits may be related .Generally one gene's product acts for many reactions and so can affect more than one trait. Examples can be seen in pea Coloured flower and pigmentation in leaf axil, frizzle trait in chicken, fur colour and deafness in cats,Human pleiotropic traits are PKU,Sickle cell Anaemia. HOsyndrome , p53 gene etc
This document presents information about penetrance and expressivity for Sir Faisal Iqbal. It defines penetrance as the percentage of individuals that show expression of a mutant genotype. Expressivity reflects the range of expression of the mutant genotype. An example is given of the eyeless gene in flies, which can result in normal eyes to complete absence of eyes. Penetrance and expressivity are used to study the degree of expression of a trait quantitatively. Phenotypic mutations can occur due to reasons other than genotype, such as genetic background and environmental factors.
This power point presentation is designed to explain deviation of Mendelian dihybrid ratio due to interaction of genes which may be of following types
1.Two gene pairs affecting same character – 9:3:3:1
2.Epistasis, one gene hides effect of other
a) Recessive Epistasis - 9:3:4
b) Dominant epistasis - 12:3:1
3.Complementary genes - 9:7 ( 2 genes responsible for production of a particular phenotype )
4. Duplicate genes – 15:1 ( same effect given by either of two genes )
5. Polymeric gene action - 9:6:1
6. Inhibitory gene action - 13 : 3
Each interaction is typical in itself and ratios obtained are different
This PPT consists of 24 slides explaining Polygenic Inheritance . Some traits are controlled by two or more genes. These traits differ from Mendelian traits and donot show discrete alternative or contrasting forms and show continuous ranges. Examples of such traits are wheat seed colour, plant height, Human skin colour controlled by at least three genes showing many shades of dark and fare, human height, human eye colour etc
Basics of Undergraduate/university fellows
Complementation between two non-allelic genes (C and P) are essential for production
of a particular or special phenotype i.e., complementary factor.
Two genes involved in a specific pathway and their functional products are required
for gene expression, then one recessive allelic pair at either allelic pair would result in
the mutant phenotype.
When Dominant alleles are present together, they complement each other to yield
complementary factor resulting in a special phenotype.
They are called complementary genes.
When either of gene loci have homozygous recessive alleles (i.e., genotypes of ccPP,
ccPp, CCpp, Ccpp and ccpp), they produce identical phenotypes and change F2 ratio
to 9:7.
This theory proposes that hereditary traits are transmitted from one generation to the next through chromosomes and gametes. Gametes contain only one set of chromosomes and fuse during fertilization to restore the paired chromosome condition. Chromosomes are replicated and passed from parents to offspring, behaving in accordance with Mendel's laws of inheritance and explaining the mechanism of inheritance. Sex is determined by sex chromosomes, which can be of the XX-XY, ZZ-ZW, or XX-XO types.
This document discusses Gregor Mendel's laws of inheritance based on his experiments breeding pea plants. It defines key genetic terms and describes Mendel's three laws: 1) The Law of Dominance states that one allele is dominant over the recessive allele. 2) The Law of Segregation states that alleles segregate and pass to offspring independently during gamete formation. 3) The Law of Independent Assortment states that different genes assort independently of one another during gamete formation. Mendel's laws established basic principles of heredity and laid the foundation for genetics.
Inbreeding occurs when related individuals mate and can increase the proportion of homozygosity. This raises the chances that offspring will be affected by recessive or deleterious traits, leading to genetic disorders and conditions. Inbreeding depression can result in smaller litters, lower fertility, and stillborn or deformed offspring in experiments with animals like adders. The inbreeding coefficient is used to measure inbreeding depression based on the expected and observed heterozygosity within a population. While inbreeding can establish desirable traits in livestock, it generally reduces survival and fertility over time.
Gene action and modification of mendelianBruno Mmassy
This document discusses several types of gene action and inheritance patterns, including complete dominance, incomplete dominance, codominance, overdominance, gene interactions, epistasis, pleiotropy, sex-linked genes, penetrance, and essential genes. It provides examples for each type, such as ABO blood groups showing codominance and coat color in mice demonstrating epistasis.
Heritability is the proportion of phenotypic variation caused by genetic factors rather than environmental factors. It can be estimated as broad sense heritability, using total genetic variance, or narrow sense heritability, using only additive genetic variance. High heritability combined with high genetic advance indicates a character is controlled by additive genes and is best improved through selection. Low heritability with low genetic advance means a character is strongly influenced by the environment. Heritability and genetic advance help plant breeders understand the genetic basis of traits and determine the most effective breeding methods.
This document discusses different types of gene interaction:
1. It defines gene interaction as two or more genes affecting the expression of a single character in an organism.
2. It classifies gene interactions into allelic/non-epistatic interactions which follow classical Mendelian ratios, and non-allelic/epistatic interactions where genes on the same or different chromosomes interact.
3. Epistatic genes suppress or mask the expression of other genes, called hypostatic genes. Epistatic gene interactions are further classified into six types based on how the genes influence each other.
This document discusses Mendelian and non-Mendelian inheritance. It provides examples of cytoplasmic inheritance including the inheritance of chloroplast genes in Mirabilis jalapa, where the phenotype is determined by the genotype of the female parent through cytoplasmic/plastid transmission, not the genes in the nucleus. It also discusses inheritance involving cytoplasmic particles like kappa particles in Paramecium, which are transmitted maternally but whose production is controlled by nuclear genes. The key differences between Mendelian and non-Mendelian inheritance are summarized in a table.
Polygenic inheritance involves multiple genes contributing to a trait, as opposed to single-gene inheritance. It can result in continuous variation, where a wide range of phenotypes exist between extremes. Human skin color and wheat seed color are examples of polygenic traits that show continuous variation, with skin color determined by 3-4 genes influencing melanin production and seed color by 3 genes determining red pigment levels.
Epistasis refers to the phenomenon where the effect of one gene is dependent on the presence of other genes. There are different types of epistatic interactions: dominant epistasis occurs when a dominant allele of one gene masks the effect of alleles at another gene locus; recessive epistasis occurs when a recessive allele of one gene hides the effects of alleles at another locus; and duplicate recessive genes, or complementary genes, produce the same phenotype only when both genes have homozygous recessive alleles. Epistasis can modify expected Mendelian ratios from crosses.
This Power Point Presentation is designed to explain Mendel's experiment on hybridization and dihybrid cross which considers inheritance of two traits at a time and to know whether they are inherited independently or are influenced by each other and also about Law of Independent assortment
This document provides an overview of gene epistasis. It defines epistasis as the phenomenon where the effect of one gene is dependent on the presence of another gene. It discusses the different types of epistatic interactions, including dominant and recessive epistasis. As an example, it describes how epistasis influences human hair color through the interaction of genes that control production of eumelanin and pheomelanin. The document emphasizes that epistasis is important for understanding genetic pathways and evolutionary dynamics.
The chromosome theory of inheritance states that chromosomes contain genes and are responsible for Mendel's principles of segregation and independent assortment during meiosis. Thomas Hunt Morgan's experiments with fruit flies led to the discovery of sex linkage, where genes on the X chromosome show different inheritance patterns between males and females. Nettie Stevens' analysis of beetle karyotypes revealed that females have two X chromosomes while males have one X and one Y chromosome, establishing the sex chromosome system. Morgan then used this information to propose X-linked inheritance for white eye color in fruit flies, providing support for the chromosome theory of inheritance.
This document discusses quantitative inheritance, which refers to inheritance of traits that are influenced by multiple genes and the environment. Quantitative traits show continuous variation and are influenced by small effects from many genes. Examples discussed include human height, skin color, and kernel color in wheat. The kernel color experiment of Nilsson-Ehle is used to demonstrate quantitative inheritance. It involved crossing two wheat varieties and analyzing the ratios of kernel color phenotypes in the offspring. For the experiment to work well, the genes influencing color needed to have additive effects and the environment could not impact phenotypes. The experiment helped establish that quantitative traits are influenced by multiple independent gene loci.
This document provides an overview of genetics and key concepts from Gregor Mendel's experiments. It introduces Mendel's work with pea plants, the principles of inheritance he established including dominance, segregation and independent assortment. It explains genetic crosses such as monohybrid and dihybrid through the use of Punnett squares. The document also discusses examples of genetic inheritance patterns in humans including cystic fibrosis and Gaucher disease. It concludes with a brief overview of concepts beyond Mendelian genetics like incomplete dominance.
This document provides an overview of genetics concepts including:
- Gregor Mendel's experiments with pea plants that established the principles of heredity and inheritance patterns
- Key genetics terms like genotype, phenotype, alleles, homozygous, heterozygous
- How Mendel used monohybrid and dihybrid crosses to study single and double trait inheritance through Punnett squares
- His principles of dominance, segregation, and independent assortment
- Examples of genetic inheritance patterns in humans like cystic fibrosis and Gaucher disease
- Exceptions to Mendelian genetics through incomplete dominance seen in snapdragon flower color
Genetics is the study of genes.
Inheritance is how traits, or characteristics, are passed on from generation to generation.
Chromosomes are made up of genes, which are made up of DNA.
Genetic material (genes,chromosomes, DNA) is found inside the nucleus of a cell.
Gregor Mendel is considered “The Father of Genetics"
This document provides an overview of genetics concepts including:
- Gregor Mendel's experiments with pea plants that established the principles of heredity and inheritance patterns
- Key genetics terms like genotype, phenotype, alleles, homozygous and heterozygous
- Mendel's principles of dominance, segregation and independent assortment observed through monohybrid and dihybrid crosses
- Examples of inheritance patterns for traits like flower color, stem length and human diseases like cystic fibrosis
- Extensions of Mendelian genetics including incomplete dominance observed in snapdragon flower color.
1) This document summarizes Gregor Mendel's experiments with pea plants that established the basic principles of heredity and inheritance through genetics.
2) Mendel performed crosses involving one or two traits, such as plant height and seed color, and observed predictable inheritance patterns including dominance and independent assortment of genes.
3) His work demonstrated that traits are passed from parents to offspring through discrete units of heredity now called genes.
This lecture covers the basics of genetics including an introduction to Gregor Mendel's experiments with pea plants, genetic terminology, monohybrid and dihybrid crosses using Punnett squares, Mendel's principles of inheritance, and concepts beyond Mendel like incomplete dominance. Key points covered include Mendel discovering the basic principles of heredity through studying traits in pea plants, how dominant and recessive alleles are inherited in monohybrid and dihybrid crosses according to his principles, and the concept of incomplete dominance in traits like flower color.
genetics introduction - models of inheritancemed zar
1. The document discusses genetics concepts including genes, alleles, genotypes, phenotypes, Mendel's laws of inheritance, and models of inheritance.
2. It provides examples of Mendel's experiments with pea plants and dihybrid crosses, demonstrating dominant and recessive traits.
3. Different inheritance patterns are described such as complete dominance, albinism, PKU, and blood types. Pedigree analysis is also discussed.
Genetics is a branch of biology concerned with the study of genes, genetic variation, and heredity in organisms. Though heredity had been observed for millennia, Gregor Mendel, Moravian scientist and Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene.
Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded beyond inheritance to studying the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the context of a population. In science and especially in mathematical studies, a variational principle is one that enables a problem to be solved using calculus of variations, which concerns finding functions that optimize the values of quantities that depend on those functions.
This document provides an overview of genetics concepts including classical genetics, molecular genetics, and evolutionary genetics. It discusses Mendel's laws of inheritance including dominance, segregation, and independent assortment. It defines key genetics terms like genotype, phenotype, homozygous, heterozygous, alleles, and genes. It also covers exceptions to Mendel's laws including incomplete dominance, codominance, and lethal alleles. Finally, it discusses linkage and crossing over between genes located on the same chromosome.
Science Notes. Probability, Mendel and GeneticsMrs. Henley
Mendel conducted experiments crossing purebred pea plants that differed in traits like plant height. He found that when crossing a tall plant with a short plant, the offspring were all tall. However, when he had these offspring self-pollinate, their offspring consisted of 3/4 tall plants and 1/4 short plants. This provided evidence that traits are passed from parents to offspring through discrete factors that we now call genes. Mendel's work established foundations of genetics including dominant and recessive alleles, genotypes and phenotypes.
This document provides an overview of genetics and Mendelian inheritance. It discusses how Mendel conducted experiments on pea plants to develop the principles of heredity, including his laws of inheritance. Mendel showed that traits are inherited as discrete units (genes) that assort independently, with one trait (dominant) masking the expression of another (recessive) trait. His work demonstrated monohybrid and dihybrid crosses, and laid the foundations for modern genetics.
Principles of Inheritance, Class 12 CBSEblessiemary
This document provides information about principles of inheritance and variation in genetics. It discusses key topics including:
- Genetics deals with inheritance and variation from parents to offspring. Variation results in offspring differing from parents.
- Gregor Mendel conducted experiments with pea plants in the 1800s and established the principles of heredity, including dominance, segregation, independent assortment. He demonstrated genes are passed from parents to offspring in predictable ratios.
- Chromosomal theory of inheritance later explained that genes are located on chromosomes and segregate during gamete formation according to Mendel's laws. The work of Morgan, Sutton, and Boveri supported this theory through experimentation.
- Genetics is the science of heredity and variation. It studies how traits are passed from parents to offspring through genes and chromosomes.
- Chromosomes contain DNA and genes which determine inherited traits. Genes can be dominant or recessive.
- Mendel's experiments with pea plants established the laws of inheritance including dominance, segregation and independent assortment. His work laid the foundation for genetics.
Genetics is the study of heredity and genes. Gregor Mendel conducted experiments with pea plants in the 1800s that formed the basis of genetics. Through his work, he discovered the principles of inheritance, including that traits are determined by units now called genes, genes occur in different forms called alleles, dominant alleles mask recessive alleles, and alleles assort independently during gamete formation. Mendel's principles can be used to predict the results of genetic crosses and the inheritance of traits.
Unit v patterns ofinheritance mendelian inheritanceDeepa Lashkari
1. Gregor Mendel conducted breeding experiments with pea plants in the 1860s to study inheritance patterns of traits. Through his experiments, he discovered three laws of inheritance: the law of dominance, the law of segregation, and the law of independent assortment.
2. Mendel's experiments showed that factors (now known as genes) are passed unchanged from parents to offspring, and that inherited traits are determined by alternative versions (alleles) of these factors.
3. Mendel's laws explain inheritance of human traits and diseases such as cystic fibrosis, which follows a recessive pattern of inheritance where both parents must carry the recessive allele for a child to be affected.
This document provides an overview of genetics and key concepts from Gregor Mendel's experiments. It introduces Mendel's work with pea plants and how he established the principles of heredity through monohybrid and dihybrid crosses. His work demonstrated that traits are inherited through discrete units called genes. The document also defines important genetic terminology and concepts such as dominant/recessive alleles, genotypes, phenotypes and Punnett squares. It discusses how Mendel's principles apply universally, using the example of cystic fibrosis inheritance in humans. The principle of independent assortment and exceptions like incomplete dominance in snapdragons are also summarized.
Genetics is the study of genes, heredity, and genetic variation. Gregor Mendel conducted experiments with pea plants in the 1800s and established the principles of inheritance, including dominance, segregation, and independent assortment. His work showed that traits are passed from parents to offspring through discrete units called genes. Monohybrid and dihybrid crosses examine the inheritance of one or two traits and can be represented using Punnett squares. Mendel's principles form the basis of modern genetics.
1. Mendel conducted breeding experiments with pea plants over seven years to test his particulate hypothesis of inheritance. He found that traits are passed from parents to offspring as distinct factors, now called genes.
2. Mendel discovered that traits can be dominant or recessive, and that alleles segregate independently during gamete formation according to his laws of inheritance.
3. Mendel's work established the foundations of classical genetics and showed that heredity follows predictable statistical patterns. His principles help explain the inheritance of human traits and disorders like cystic fibrosis.
Gregor Mendel conducted the first recorded scientific study of heredity by breeding pea plants. Through his experiments, he discovered that traits are passed from parents to offspring through discrete units (now known as genes). Mendel determined that some traits are dominant and will mask recessive traits, and that traits are inherited independently of each other. His work established the basic principles of genetics and heredity.
Similar to Mendellian Inheritance and Gene Action (20)
This document discusses mutation, including its definition, types, and causes. Some key points:
- H.J. Muller first demonstrated induced mutation using X-rays in 1927 and won the Nobel Prize in 1949 for his contributions to genetics research.
- Mutation is defined as a sudden heritable change in an organism's phenotype or nucleotide sequence not due to segregation or recombination.
- Mutations can be induced artificially using physical mutagens like radiation or chemical mutagens like alkylating agents.
- At the molecular level, point mutations involve changes in a gene's base sequence and can be substitutions, deletions, or additions of nucleotide bases.
DNA is composed of nucleotides, each containing a nitrogenous base, a pentose sugar, and a phosphate group. The two types of pentose sugars are deoxyribose in DNA and ribose in RNA. There are two types of nitrogenous bases - purines (adenine and guanine) and pyrimidines (cytosine, thymine, and in RNA, uracil). Watson and Crick proposed that DNA exists as a double helix with the bases pairing together between the two anti-parallel strands - adenine pairs with thymine and guanine pairs with cytosine. The structure allows DNA to self-replicate and transmit genetic information to daughter cells during cell division.
The document discusses the objectives of plant breeding for several crops including chilli, brinjal, and okra. The main objectives discussed are:
1. Developing improved varieties that have higher yields, better quality, disease and insect resistance, and other desirable traits to be commercially successful.
2. Breeding objectives for individual crops include earliness, desirable fruit/pod characteristics, quality, resistance to diseases and insects, and tolerance to abiotic stresses.
3. Information is provided on the origin, distribution, species, and popular varieties of chilli, brinjal, and okra, which are important vegetable crops grown in India and other countries.
Inbreeding can lead to inbreeding depression, which refers to a reduction in fitness and fertility. The degree of inbreeding depression varies between species. Some species, like alfalfa and carrot, show high inbreeding depression and a large proportion of inbred plants do not survive or have reduced fertility. Other species, like onions and sunflowers, show low inbreeding depression with only small effects on survival and fertility. This difference in response is due to whether a species has evolved to be heterozygous or homozygous. Cross-pollinated species tend to be highly heterozygous and show inbreeding depression, while self-pollinated species are naturally homozygous and do not exhibit inbreeding depression.
The document summarizes the cell cycle, cell division, mitosis, and meiosis. The cell cycle consists of interphase and cell division. Interphase includes G1, S, and G2 phases where DNA is synthesized. Cell division includes karyokinesis and cytokinesis. Mitosis produces identical daughter cells through prophase, metaphase, anaphase, and telophase. Meiosis reduces chromosome number by half and produces genetic variation through homologous chromosome pairing, crossing over, and two cell divisions. Meiosis is important for sexual reproduction and genetic recombination.
This document discusses modes of reproduction in crop plants, including both asexual and sexual reproduction. It provides details on different types of asexual reproduction such as vegetative reproduction (through underground stems, bulbs, etc.) and apomixis. It also discusses various aspects of sexual reproduction including self-pollination and cross-pollination. Key consequences of different modes of reproduction like heterozygosity, inbreeding depression and heterosis are summarized. The document aims to provide a comprehensive overview of modes of reproduction and their significance for plant breeding and genetics.
Chapter wise All Notes of First year Basic Civil Engineering.pptxDenish Jangid
Chapter wise All Notes of First year Basic Civil Engineering
Syllabus
Chapter-1
Introduction to objective, scope and outcome the subject
Chapter 2
Introduction: Scope and Specialization of Civil Engineering, Role of civil Engineer in Society, Impact of infrastructural development on economy of country.
Chapter 3
Surveying: Object Principles & Types of Surveying; Site Plans, Plans & Maps; Scales & Unit of different Measurements.
Linear Measurements: Instruments used. Linear Measurement by Tape, Ranging out Survey Lines and overcoming Obstructions; Measurements on sloping ground; Tape corrections, conventional symbols. Angular Measurements: Instruments used; Introduction to Compass Surveying, Bearings and Longitude & Latitude of a Line, Introduction to total station.
Levelling: Instrument used Object of levelling, Methods of levelling in brief, and Contour maps.
Chapter 4
Buildings: Selection of site for Buildings, Layout of Building Plan, Types of buildings, Plinth area, carpet area, floor space index, Introduction to building byelaws, concept of sun light & ventilation. Components of Buildings & their functions, Basic concept of R.C.C., Introduction to types of foundation
Chapter 5
Transportation: Introduction to Transportation Engineering; Traffic and Road Safety: Types and Characteristics of Various Modes of Transportation; Various Road Traffic Signs, Causes of Accidents and Road Safety Measures.
Chapter 6
Environmental Engineering: Environmental Pollution, Environmental Acts and Regulations, Functional Concepts of Ecology, Basics of Species, Biodiversity, Ecosystem, Hydrological Cycle; Chemical Cycles: Carbon, Nitrogen & Phosphorus; Energy Flow in Ecosystems.
Water Pollution: Water Quality standards, Introduction to Treatment & Disposal of Waste Water. Reuse and Saving of Water, Rain Water Harvesting. Solid Waste Management: Classification of Solid Waste, Collection, Transportation and Disposal of Solid. Recycling of Solid Waste: Energy Recovery, Sanitary Landfill, On-Site Sanitation. Air & Noise Pollution: Primary and Secondary air pollutants, Harmful effects of Air Pollution, Control of Air Pollution. . Noise Pollution Harmful Effects of noise pollution, control of noise pollution, Global warming & Climate Change, Ozone depletion, Greenhouse effect
Text Books:
1. Palancharmy, Basic Civil Engineering, McGraw Hill publishers.
2. Satheesh Gopi, Basic Civil Engineering, Pearson Publishers.
3. Ketki Rangwala Dalal, Essentials of Civil Engineering, Charotar Publishing House.
4. BCP, Surveying volume 1
This presentation was provided by Steph Pollock of The American Psychological Association’s Journals Program, and Damita Snow, of The American Society of Civil Engineers (ASCE), for the initial session of NISO's 2024 Training Series "DEIA in the Scholarly Landscape." Session One: 'Setting Expectations: a DEIA Primer,' was held June 6, 2024.
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...Dr. Vinod Kumar Kanvaria
Exploiting Artificial Intelligence for Empowering Researchers and Faculty,
International FDP on Fundamentals of Research in Social Sciences
at Integral University, Lucknow, 06.06.2024
By Dr. Vinod Kumar Kanvaria
This document provides an overview of wound healing, its functions, stages, mechanisms, factors affecting it, and complications.
A wound is a break in the integrity of the skin or tissues, which may be associated with disruption of the structure and function.
Healing is the body’s response to injury in an attempt to restore normal structure and functions.
Healing can occur in two ways: Regeneration and Repair
There are 4 phases of wound healing: hemostasis, inflammation, proliferation, and remodeling. This document also describes the mechanism of wound healing. Factors that affect healing include infection, uncontrolled diabetes, poor nutrition, age, anemia, the presence of foreign bodies, etc.
Complications of wound healing like infection, hyperpigmentation of scar, contractures, and keloid formation.
Strategies for Effective Upskilling is a presentation by Chinwendu Peace in a Your Skill Boost Masterclass organisation by the Excellence Foundation for South Sudan on 08th and 09th June 2024 from 1 PM to 3 PM on each day.
বাংলাদেশের অর্থনৈতিক সমীক্ষা ২০২৪ [Bangladesh Economic Review 2024 Bangla.pdf] কম্পিউটার , ট্যাব ও স্মার্ট ফোন ভার্সন সহ সম্পূর্ণ বাংলা ই-বুক বা pdf বই " সুচিপত্র ...বুকমার্ক মেনু 🔖 ও হাইপার লিংক মেনু 📝👆 যুক্ত ..
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তাই একজন নাগরিক হিসাবে এই তথ্য গুলো আপনার জানা প্রয়োজন ...।
বিসিএস ও ব্যাংক এর লিখিত পরীক্ষা ...+এছাড়া মাধ্যমিক ও উচ্চমাধ্যমিকের স্টুডেন্টদের জন্য অনেক কাজে আসবে ...
How to Manage Your Lost Opportunities in Odoo 17 CRMCeline George
Odoo 17 CRM allows us to track why we lose sales opportunities with "Lost Reasons." This helps analyze our sales process and identify areas for improvement. Here's how to configure lost reasons in Odoo 17 CRM
How to Add Chatter in the odoo 17 ERP ModuleCeline George
In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
Walmart Business+ and Spark Good for Nonprofits.pdfTechSoup
"Learn about all the ways Walmart supports nonprofit organizations.
You will hear from Liz Willett, the Head of Nonprofits, and hear about what Walmart is doing to help nonprofits, including Walmart Business and Spark Good. Walmart Business+ is a new offer for nonprofits that offers discounts and also streamlines nonprofits order and expense tracking, saving time and money.
The webinar may also give some examples on how nonprofits can best leverage Walmart Business+.
The event will cover the following::
Walmart Business + (https://business.walmart.com/plus) is a new shopping experience for nonprofits, schools, and local business customers that connects an exclusive online shopping experience to stores. Benefits include free delivery and shipping, a 'Spend Analytics” feature, special discounts, deals and tax-exempt shopping.
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Spark Good (walmart.com/sparkgood) is a charitable platform that enables nonprofits to receive donations directly from customers and associates.
Answers about how you can do more with Walmart!"
3. Genetics Terminology: Chromosomes & Genes
• ________ -
Complete complement
of an organism’s DNA.
• Cellular DNA is
organized in
___________.
• ______ have specific
places on chromosomes.
Image: Chromosome & gene, Graham Colm,
National Human Genome Research Institute
4. So who was Mendel?
• Once upon a time (1860's), in an Austrian monastery,
there lived a monk named Gregor Mendel.
• Mendel spent his spare time breeding pea plants.
• He did this over & over & over again, and noticed patterns
to the inheritance of traits, from one set of pea plants to
the next.
• By carefully analyzing his pea plant numbers, he
discovered three laws of inheritance.
• Mendel's Laws are as follows:
1. Law of Dominance
2. Law of Segregation
3. Law of Independent Assortment
• In his work, the words "chromosomes" or "genes" are nowhere to
be found. The role of these things in relation to inheritance &
heredity had not been discovered yet.
• What makes Mendel's contributions so impressive is that he
described the basic patterns of inheritance before the
mechanism for inheritance (namely genes) was even discovered!
The dude
was a
total
GENIUS!
Image: Gregor Mendel, Mendel's Principles of Heredity: A Defense
by Bateson, William; Spicoli from Fast Times at Ridgemont High
5. First, a little more genetics terminology.
Then…
Mendel's Laws
1. Law of Dominance
2. Law of Segregation
3. Law of Independent Assortment
Image: Gregor Mendel, Mendel's Principles
of Heredity: A Defense by Bateson, William.
6. Mendel’s experiments
• Convenience of handling
• Controlled mating
• Short life cycle
• Large number of fertile
off-springs
• Presence of variation
Characters chosen by Mendel for his study
Character Dominant form Recessive form
1. Plant height Tall Dwarf
2. Seed texture Round Wrinkled
3. Seed colour Yellow Green
4. Flower colour Violet White
5. Pod colour Green Yellow
6. Pod shape Inflated Constricted
7. Position of flowers Axial Terminal
7. Genetics Terminology
• Genotype: the genes of an
organism (all your genes)
• Phenotype: an organism’s traits
(expression of your genes)
• Allele: variations of a gene
• Represented with letters for
the different types of alleles
(PP, Pp, pp)
• homozygous: pair of identical
alleles for a character (PP, pp)
• heterozygous: two different
alleles for a gene (Pp)
8. Genetics Terminology
• Character: heritable feature (i.e.,
fur color)
• Trait: variant for a character (i.e.
brown)
• True-bred: all offspring of same
variety
• Hybridization: crossing of 2
different true-breds
• Hereditary variation: refers
to the differences in the inherited
traits.
• Environmental Variation: It is
entirely due to environment.
We label the different
generations of a cross as:
• P generation (parents)
• F1 generation (1st filial generation)
• F2 generation (2nd filial generation)
9. Genetics Terminology
___ ___ ___ ___
___ ___
Q: Would “Harriet” be able to roll her tongue?
Dominant & Recessive
Genotypes & Phenotypes
____________ genotype:
Both recessive alleles must be present (rr).
___________ genotype:
At least one dominant allele is present (R-).
Character: Tongue Rolling
Being able to roll your tongue is a dominant
phenotype.
Harry: Being able to roll your tongue is the dominant trait
(phenotype). Q: How would we represent the genotype of he
was homozygous dominant?
Hermione: Not being able to roll your tongue is the
recessive (phenotype). Q: What would be the recessive
genotype?
10. • In a cross of parents that
are pure for contrasting
traits, only one form of the
trait will appear in the next
generation.
• Offspring that are hybrid
for a trait will have only the
dominant trait in the
phenotype.
• States that in a hybrid one
factor of the allelomorphic
pair expresses itself
completely over the other.
1. Mendel’s Law of _________
Image: Simple Inheritance, complete
dominance, Magnus Manske
11. 2. Mendel’s Law of ________
• A pair of alleles /
allelomorphs is brought
together in a hybrid (F 1)
they remain together
without contaminating each
other
• they separate or segregate
from each other into a
gamete in a complete and
pure form during the
formation of gametes.
• The alleles for each
character segregate
(separate) during gamete
production (_______).
• Alleles for a trait are
recombined at fertilization,
becoming genotype for the
traits of the offspring.
Image: Independent assortment and
segregation diagram, Mariana Ruiz.
Table showing how
the genes exchange
according to
segregation or
independent
assortment during
meiosis and how this
translates into
Mendel's laws.
12. • Alleles for different traits
are distributed to sex cells
(& offspring) independently
of one another.
• The factors in an
allelomorphic pair separates
independently to the
separation of factors in the
other allelomorphic pair.
Remember…Mendel came up with
this stuff BEFORE we know
about the existence of DNA,
genes, chromosomes.
WOW!
3. Mendel’s Law of _____ ______
Image: Independent assortment and
segregation diagram, Mariana Ruiz.
Diagram of how the
genes exchange
according to
segregation or
independent
assortment during
meiosis and how this
translates into
Mendel's laws.
13. Mendel’s Laws:
1. Law of Dominance:
- States that in a hybrid one factor of the allelomorphic
pair expresses itself completely over the other.
2. Law of Segregations:
- During the formation of gametes (eggs or sperm), the two alleles
(hereditary units) responsible for a trait separate from each other.
- Alleles for a trait are then "recombined" at fertilization, producing the
genotype for the traits of the offspring.
3. Law of Independent Assortment:
- The factors in an allelomorphic pair separates independently to the separation
of factors in the other allelomorphic pair.
Image: Gregor Mendel, Mendel's Principles of
Heredity: A Defense by Bateson, William
14. Monohybrid cross
(cross with only 1 trait)
Problem:
Using this is a several step process, look at
the following example
Tallness (T) is dominant over shortness (t)
in pea plants. A Homozygous tall plant (TT)
is crossed with a short plant (tt). What is
the genotypic makeup of the offspring?
The phenotypic makeup?
15. 1. Determine alleles of
each parent, these are
given as TT, and tt
respectively.
2. Take each possible
allele of each parent,
separate them, and
place each allele either
along the top, or along
the side of the punnett
square.
Tt Tt
Tt Tt
16. Here we have some more
interesting results:
First we now have 3
genotypes (TT, Tt, & tt)
in a 1:2:1 genotypic
ratio. We now have 2
different phenotypes
(Tall & short) in a 3:1
Phenotypic ratio. This is
the common outcome
from such crosses.
17. Dihybrid crosses
Dihybrid crosses are made when phenotypes
and genotypes composed of 2 independent
alleles are analyzed.
Process is very similar to monohybrid crosses.
Example:
2 traits are being analyzed
Seed colour(Yy) with yellow being dominant
green,
Seed shape (Rr) with round being dominant
to wrinkled.
18. Dihybrid cross example
The cross with a pure-breeding (homozygous) Yellow, Round seed plant
with a pure-breeding green,wrinkled plant should look like this.
19. Reasons for success of Mendel
• The experiments were very well designed & conducted with great care and skill.
• The choice of his experimental material.
• Mendel studied the inheritance of only characters at a time.
• The characters he chose were well defined and simple.
• The seven characters selected by Mendel showed qualitative inheritance.
• The contrasting forms of each of case one form was completely dominant over
other.
• His knowledge on mathematics was a definite asset for the interpretation of his
findings.
• He maintained particulars of pedigree records, which gave him the exact
ancestry of any given plant.
20. Figuring Out Patterns of Inheritance
A Punnett square is a tool for
diagramming the possible
genotypes of offspring.
• Let do a Punnett square for the
trait of round seed shape is
dominant over wrinkled seed
shape.
• Round seed shape
- dominant phenotype
- Q: What is gentoype?
• Wrinkled seed shape
- Recessive phenotype
- Q: What is genotype?
F1 (Progeny)
- Dominant phenotype [round seed shape]
- Q: What is F1 genotype?
Male parennt Genotype:
Female
parent
Genotype:
Generation Parental
Parents Female X Male
Phenotype Round X Wrinkled
Genotype RR X rr
Gametes R r
Generation F1 Rr
(Heterozygous) Round
F2 F1 XF1
R
R r
r
RR
Round
Rr
Round
Rr
Round
rr
Wrinkled
21. So far, we’ve discussed
Simple Inheritance &
Punnett Squares…
But, of course, genetic is
much more complicated
than that.
Let’s explore:
• Complete dominance
• Incomplete dominance
• Co-dominance
• Over dominance
A Punnett square
22. • Complete dominance:
• The phenotype produced by a
heterozygote is identical to
that produced by the
homozygotes for the
concerned dominant allele.
• The dominant allele in such a
situation is said to be
completely or fully dominant.
Eg: In garden pea, round seed shape is
completely dominant over wrinkled.
Round x Wrinkled
RR rr
F1 Rr
r
Wrinkled
R
Round
Rr
Round
23. • Incomplete dominance: In many
cases, the intensity of
phenotype produced by
heterozygote is less than that
produced by the homozygote for
the concerned dominant allele.
• Therefore the phenotype of
heterozygote falls between
those of the homozygotes for
the two concerned alleles.
• Such a situation is known as
Incomplete or partial dominance
and the dominant allele is called
incompletely dominant or
partially dominant.
Eg : In Mirabilis jalapa (Four ‘O’ clock plant)
a partially dominant allele ‘R’ produces red
flowers in homozygous state, while its
recessive allele ‘r’ produces white flowers
in homozygous state. When a red (RR)
flower type plant is crossed with white
(rr) flower type plant, the hybrid (Rr) has
pink flowers.
Red x White
RR x rr
F1 Rr
r
White
R
Red
Rr
Pink
24. • Co-dominance: Both the
alleles of a gene express
themselves in heterozygotes.
• As a result, heterozygotes
for such genes possess the
phenotypes produced by both
the concerned alleles.
• The coat colour of short horned
breed of cattle presents an
excellent example of
codominance. Roan colour is that
which has patches of red and
white colours.
Red x White
CR C R x Cr C r
F1
Cr
White
CR
Red
CR Cr
Roan
25. Co-domiance : of human blood
- Has three alleles: A, B & O
- AB co-dominant, O recessive
- Genotype represented using
IA, IB & i
Phenotype Genotype
Type A IAIA or IAi
Type B IBIB or IBi
Type AB IAIB
Type O ii
Image: ABO blood type, InvictaHOG
26. ABO Blood Type
You make antibodies against the
antigens of other blood types. .
– Q: Which blood type can
accept anyone's blood.
– Q: Which blood type is known
as the “universal donor. Why?
Image: ABO blood type, InvictaHOG
Phenotype Genotype
Type A IAIA or IAi
Type B IBIB or IBi
Type AB IAIB
Type O ii
27. • Over dominance: In case of some
genes, the intensity of character
governed by them is greater in
heterozygotes than in the two
concerned homozygotes.
• This situation is known as over-
dominance.
• True over dominance is known in case
of very few genes.
• Over-dominance is not the property
of an allele but is the consequence
of heterozygous state of concerned
gene.
Transgressive segregation: The
appearance of individuals in F2 or
subsequent generation which exceed the
parental types with reference to one or
more characters is known as
transgressive segregation. Or
The segregants which fall outside the
range of both the parents are called
transgressive segregants and the
phenomenon is called transgresive
segregation.
Eg: white eye gene (W) of Drosophila
exhibits overdominance for some of
the eye pigments such as
sepiapteridine and Himmel blaus.
These two eye pigments are present
in low concentration in the recessive
homozygotes (ww), while the
dominant homozygotes (WW) have
relatively higher concentrations of
these pigments. However, the flies
heterozygous for this gene (Ww)
have an appreciably higher
concentration of these two pigments
than the two homozygotes.
28. Exceptions to Mendel’s laws:
• Paramutations and polyploidy are exceptions to the law of
segregation or law of purity of gametes.
• Linkage is an exception to Mendel’s second law i.e. law of
independent assortment.
• Incomplete dominance is an exception to the principle of
dominance.
• Pleiotropism is an exception to the principle of unit characters.
• Modification of F2 ratios due to incomplete -dominance, co-
dominance, lethalfactors, interaction of factors, epistatic
factors are all exceptions.
30. GENE ACTION
• Gene action refers to the manner in which genes control
the phenotypic expression of various characters in an
organism.
• Alleles of the gene may interact with one another in a
number of ways to produce variability in their phenotypic
expression.
• The dominant and recessive relationship is fundamental
and is essentially constant with each pair of alleles.
31. Gene action can be of the following types:
1. Based on the dominance effect:
a) Complete dominance
b) Incomplete dominance
c) Co-dominance
d) Over dominance
e) Pseudo-dominance
2. Based on lethal effects :
a) Dominant lethals
b) Recessive lethals
3. Based on epistatic action :
a) Epistatic factors
b) Supplementary factors
c) Duplicate factors
d) Complementary factors
e) Additive factors
f) Inhibitory factors
4. Based on number of genes involved:
a) Monogenic
b) Digenic
c) Oligogenic
d) Polygenic
5. Based on pleiotropism
a) Pleiotropic gene action
33. Based on the dominance effect:
• Complete dominance
• Incomplete dominance
• Co-dominance
• Over dominance
• Pseudo-dominance:
• Expression of recessive allele of the
gene in the hemizygous state /
condition either due to sex linkage
(Eg: colour blindness in human
beings) or chromosomal aberrations
(deletion in heterozygotes) is known
as pseudo-dominance.
34. Based on lethal effect:
• Dominant Lethal gene action: A
lethal gene affecting coat colour in
mice was discovered by French
geneticist Cuenot in 1905.
• He found that,
• Yellow coat colour in mice was
produced by a dominant gene ‘Y’
• recessive allele ‘y’ determines the
normal black / grey coat colour
• all the mice with yellow coat colour
were heterozygous Yy
• and he was unable to found a mouse
homozygous for ‘Y’ allele (YY).
• The dominant allele ‘Y’ is lethal and
hence it causes death of homozygous
‘YY’ embryos at an early stage of
development.
35. • Recessive lethals:
• Albino seedling character in plants such
as rice and barley is governed by
recessive alleles.
• Whenever these alleles are in the
homozygous state the seedlings are near
white or almost white and totally devoid
of chlorophyll.
• Albino seedlings survive only as long as
the food material stored in the seeds is
available to them because they are not
able to carry out photosynthesis.
• The heterozygotes, however are normal
green and are identical with the dominant
homozygotes in their phenotype as well as
their survival.
• Segregation of such genes produces 3
green : 1 albino seedling if they are
counted within a week from germination.
• However, if the plants are counted at
maturity, there will be only green plants in
the progeny.
Female x male
Green x Green
GG Gg
F1 Gg
On selfing of Gg individuals
Gg x Gg
F2
G
G g
g
GG
Green
Gg
Green
Gg
Green
gg
albino
(dies)
36. Based on epistatic gene action:
• When expression of one gene
depends on presence / absence of
another gene in an individual, it is
known as gene interaction.
• Interaction of genes at different
loci that affect the same character
is called epistasis.
• The term epistasis was first used by
Bateson in 1909 to describe two
different genes which control the
same character,
• out of which one masks / suppresses
the expression of another gene.
• Gene that masks the action of
another gene is called epistatic gene
• while the gene whose expression is
being masked is called hypostatic
gene.
Epistatic gene interaction can be of the
following types.
(i) Epistatic factors - 12 : 3 : 1
(ii) Supplementary factors - 9 : 3 : 4
(iii) Duplicate factors - 15 : 1
(iv) Complementary factors - 9 : 7
(v) Additive factors - 9 : 6 : 1
(vi) Inhibitory factors - 13 : 3
37. Epistatic factors - 12 : 3 : 1
• Also referred to as masking gene
action.
• In this, dominant alleles of two
genes affecting the same
character produce distinct
phenotypes when they are with
homozygous recessive state of the
other gene.
• But when dominant alleles of both
the genes present together, the
expression of one gene masks that
of other.
• When both the genes are present
in the recessive state, a different
phenotype is produced.
• Thus, in this case, both the genes
express themselves when their
dominant alleles are present
togather, but the expression of
one is so intance or strong that
expression of other gene cannot
be observed.
38. Supplementary factors - 9 : 3 : 4
• Dominant allele of one of the
two genes governing a character
produces a phenotypic effect.
• However, the dominant allele of
the other gene does not produce
a phenotypic on its own.
• But when it is present with the
dominant allele of the first
gene, it modifies the phenotypic
effect produced by that gene.
39. Duplicate factors - 15 : 1
• Character showing duplicate
gene action are determined by
two completely dominant genes,
which produces the same
phenotype whether they are
alone (i.e., with the recessive
allele of other gene) or
together;
• the contrasting phenotype is
produced only when both the
gene are in homozygous
recessive state
TV
TV
Tv
Tv
tV
tV
tv
tv
TTVV TTVv TtVV TtVv
TTVv TTvv TtVv Ttvv
TtVV TtVv ttVV ttVv
TtVv Ttvv ttVv ttvv
TTVV
Triangular
ttvv
Ovate
TtVv
All triangular
F1 (TtVv) x F1 (TtVv)
x
F1 generation
40. Complementary factors - 9 : 7
• In this, the production of one of
the two phenotypes of a trait
require the presence of
dominant alleles of both the
genes controlling the concerned
trait.
• When any one of the two or
both the genes are present in
the homozygous recessive state,
the contrasting phenotype is
produced.
41. • In this, one of the two completely dominant genes produces the
concerned phenotype, while its recessive allele produces the
contrasting phenotype.
• The second dominant gene, called inhibitory gene, has no effect of its
own on the character in question;
• However, it can stop the expression of the dominant allele of the first
gene.
• As a result when the two dominant genes are present together, they
produce the same phenotype as that produced by the recessive
homozygote of the first gene
Inhibitory factors - 13 : 3
42. • The two completely dominant genes controlling a character produced
identical phenotypes when their dominant alleles are present with
homozygous recessive condition of the other gene.
• But when dominant alleles of both the genes are present together,
their phenotypic effect is enhanced as if the effect of the two genes
were cumulative or additive
Additive factors - 9 : 6 : 1
43. Polygenic gene action
• In general, one gene controls or affects a single character. But some
characters are known to be controlled by more number of genes.
• Such genes are called poly genes and the phenomenon is called polymerism. Eg :
Yield in plants.
44. Pleiotropic gene action
• In general, one gene affects a single character.
• But some of the genes are known to affect or control more than one character.
• Such genes are called pleiotropic genes and the phenomenon is known as
pleiotropism.
• Many fold phenotypic expressions of a single gene is called pleiotropism or
pleiotropic gene effects.
• Eg: White eye gene effects the shape of sperm storage organs and other
structures in Drosophila.
• Good example of pleiotropism has been reported in wheat.
• A gene governing awns in Ona’s variety of wheat also increases the yield as well
as seed weight.