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Complications of Transradial
     Approach
    Olivier F. Bertrand, MD, PhD
    Associate-Professor of Medicine, Laval University
    Adjunct-Professor, Department of Mechanical Engineering, McGill University


    Quebec Heart-Lung Institute
                    DUKE TRANSRADIAL ADVANCED COURSE
                             20 OCTOBER 2011




Friday, October 21, 2011
Disclosures
                    Research grants (IIT): Cordis, Eli-Lilly,
                    Bristol-Myers-Squibb,GE Healthcare,
                    Sanofi-Aventis, Eurocor
                    Consultant: Cordis, Astra-Zeneca,
                    Opsens
                    Research-Scholar from Quebec
                    Foundation for Health Research
Friday, October 21, 2011
Upper Limb Vascularization




                            FUJII ET AL. J INV CARDIOL 2010;22:536-40

Friday, October 21, 2011
Types of Vascular
                   Complications-Common
                   Types           Radial   Femoral
            Hematoma > 5cm         < 1%      3-5%
            Pseudo-aneurysm        < 1%      <1%
                A/V Fistula        < 1‰      1-2%
               Skin infection      < 1%      <1%
            Dissection/Rupture     < 1%      <1%
                Thrombosis       <1%-10%     <1%
             Distant Bleeding        -       <1%
                Nerve Injury         -       <1%
              Atherosclerosis        ?         ?


Friday, October 21, 2011
Types of Vascular
                   Complications-Specific
                      Types                  Radial
             Compartment syndrome            < 1‰
                      Spasm                   < 1%
                 Artery avulsion             < 1‰
          Granulomatous skin reaction      case-report
                 Digital ischemia          case-report
          Transient vocal cord paralysis   case-report
              Mediastinal hematoma         case-report
           Delayed reflex sympathetic
                                           case-report
                    dystrophy
                     Catheter entrapment   case-report

Friday, October 21, 2011
Spasm
          Lack of definition...

          No brachial artery spasm...look for recurrent artery..

          Prevention >> Treatment

          Risk factors: Smoking, small vessel, anxiety

          Pharmaco: Calcium channel blockers or combo

          Devices: Small sheath, hydrophylic, sheathless

          If severe: sedation ± sympathetic block


                                                       COURTESY G BARBEAU

Friday, October 21, 2011
Pseudo-aneurysm

                            COLLINS ET AL. CCI 2011



          True incidence probably underestimated

          Importance of timing for diagnostic...

          Risk factors: hypertension, chronic anticoagulation,
          types of closure devices ?

          Rx: compression, echo-guided thrombin injection,
          NO surgery
Friday, October 21, 2011
Dissection of Radial Artery




Friday, October 21, 2011
Immediate Post-PCI
                           Angiogram
                           Same-day transfer to
                           referring center
                           No Hematoma




Friday, October 21, 2011
Friday, October 21, 2011
Friday, October 21, 2011
Friday, October 21, 2011
Friday, October 21, 2011
Friday, October 21, 2011
Bleeding at Distance from
        Puncture Site




Friday, October 21, 2011
Nursing Management




Friday, October 21, 2011
Friday, October 21, 2011
Prevention !!!!
                           TIZON H, BARBEAU G, J INTERV CARDIOL 2008
Friday, October 21, 2011
Radial Artery Occlusion




Friday, October 21, 2011
Radial Artery Occlusion




Friday, October 21, 2011
Radial Artery Occlusion




                                         BERNAT I ET AL. AM J CARDIOL 2011 (IN PRESS)

Friday, October 21, 2011
Retrograde Recanalization




Friday, October 21, 2011
Retrograde Recanalization




Friday, October 21, 2011
QHLI: Clinical Outcomes




Friday, October 21, 2011
Post Retrograde Recanalization




Friday, October 21, 2011
1 Week Post-Recanalization




Friday, October 21, 2011
Catheter Entrapment...




Friday, October 21, 2011
Friday, October 21, 2011
Radial vs Catheter Selection ?




Friday, October 21, 2011
Conclusion
            Complications of radial approach have been
            well documented
            Most are preventable
            Optimization still required for hemostasis and
            prevention/treatment of RAO
            Issue of coronary dissection ie single catheter
            manipulation needs to be explored


Friday, October 21, 2011
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Bertrand OF_2 201110