A blood clot had been silently forming in Adam Parker\'s left anterior descending coronary artery. The 53 year old advertising executive arrived at the Greenville Convention Center feeling fine, but suddenly a dull ache started in the center of his chest and he became nauseated. At first he thought it was the after effects of the convention banquet the night before. When the chest pain persisted, he thought of his family history of heart disease and took an aspirin remembering a radio ad that said to do this if you were having symptoms of a heart attack. Adam then went to the Center\'s Aid Station m not feeling well\" he told the emergency medical technician (EMT). The EMT, on hearing Adam\'s symptoms and seeing his pale, sweaty face immediately thought of a heart attack. \"let\'s get you over to the hospital and get this checked out\" When people speak of a \"heart attack\" they are actually referring to a clot that stops the blood supply to part of the heart, creating a condition known as ischemia In medical terms, a heart attack is called a myocardial infarction (MI), referring to an area of heart muscle that is dying because of a lack of blood supply. The clot in Adam\'s coronary artery had reduced the blood flow to part of his left ventricle and the myocardial cells were beginning to die from lack of oxygen. When someone has a heart attack immediate medical intervention is critical. In the ambulance the EMT gave Adam oxygen, hooked him to a heart monitor and started an intravenous (IV) injection of normal saline (isotonic). With an IV line in place other drugs could be given rapidly if Adam\'s condition worsened. Solution Myocardial infarction leads to congestive heart failure and sudden cardiac death. Oxygen supplimentation given to improve the blood oxigen saturation. In myocardial infarction there is less release of oxigen from heamoglobin leads to tissue hypoxia.the inhalation of 100% oxigen at high barometric pressure, called hyperbaric oxygen therapy.this causes increased the amount of dissolved oxygen in plasma. Which is useful to relieve from ischemia. The osmolarity is the number of osmoles per litre of solution. The solution that have same osmolarity as plasma are said to be isotonic.e.g. 0.9% sodium chloride solution. We know that, when RBC are placed in isotonic solution, they remain suspended in it, neither swell nor shrink because the osmotic pressure of isotonic solution is equal to the osmotic pressure within the RBCs. Hence, by injecting the istonic saline only extra cellular fluid volume Increase.the intra cellular fluid volume and body osmolarity remains same. Since injecting fluid is isotonic it cannot cross the membranes..