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HIV
• Acquired Immuno Deficiency Syndrome (AIDS)
• Fatal illness
• Caused by a retrovirus HIV
• It breaks down the body's immune system, leaving the patient
vulnerable to a host of life threatening opportunistic infections,
neurological disorders or unusual malignancies.
EPIDEMIOLOGY
• AGENT: HIV – HUMAN IMMUNO DEFICIENCYVIRUS
• AttacksT4 lymphocytes – Replicates inside it and destroy it
• Pass through blood brain barrier
• Two types – HIV1 and HIV2
• RESERVOIR: Cases and Carriers
• SOURCE:
• High concentration – blood, semen and CSF
• Lower concentration in other body fluids like saliva, urine etc
• HOST FACTORS:
• AGE – 20-49 most common
• SEX – more among homosexuals, Multiple partners,
Prostitutes
Mode of transmission
• SexualTransmission
• Blood contact – blood transfusion, needle injury like ear piercing,
tattooing etc
• Mother to child transmission
• INCUBATION PERIOD:
• Few months to 10 years or more
• CLINICAL MANIFESTATION:
• Initial Infection with virus and antibody development
• Asymptomatic carrier state
• AIDS –related complex (ARC)
• AIDS
DIAGNOSIS
• ELISA - Screening test for HIV – detect antibodies
• Western Blot test – Confirmatory – Detect more specific antibody
to viral core protein
CONTROL OF AIDS
• PREVENTION
1. Education
2.Combination HIV prevention
1. Biomedical
2.Behavioural
3. Structural interventions
3. Prevention of blood borne transmission
• ANTIRETROVIRAL TREATMENT:
• Nucleoside reverse transcriptase inhibitors (NRTIs)
• Nucleotide reverse transcriptase inhibitors (NtRTIs)
• Non-Nucleoside reverse transcriptase inhibitors (NNRTIs)
• Protease inhibitors (PPs)
• Integrase strand transfer inhibitors (INSTIs)
STD
• Group of communicable diseases
• Transmitted predominantly by sexual contact
• Caused by viral, bacterial, protozoan, fungi and ectoparasites
• Previously venereal disease (VD) – 5 diseases
• Syphilis, gonorrhea, chancroid, LGV and donovanosis
• Now STD – more than 20 agents
Epidemiological determinants
AGENT
• Nisseria gonorrhoeae
• Treponema pallidum
• Haemophilus ducreyi
• Chlamydia trachomatis
• Calymmatobacterium
granulomatis
• Herpes simplex virus
• Hepatitis B
• HPV
• HIV
• Molluscum contagiosum
• Candida albicans
• Trichomonas vaginalis
Host and demographic factors
• Age – 20-24 years
• Sex – morbidity male > female, severity female>male
• Marital status – single, divorced, separated
• SES – low SES
• Increased population – more younger population
• Rural to urban migration
• Delaying in female marriage
Social factors
• Prostitution
• Broken homes
• Sexual disharmony
• Easy money
• Emotional immaturity
• Urbanization
• Social disruption - war
• International travel
• Changing behavior pattern
• Social stigma
• Alcoholism
Clinical spectrum
• Gonococcal infection
• Inflammation – urethra and rectum in male, cervix and rectum
in female
• Complications – PID – ectopic pregnancy, infertility, chronic
pelvic pain
• In men – epididymis
• Treatment – cefixime, ciprofloxacin
Syphilis
• Ulceration of urogenital tract, mouth or rectum
• Skin eruptions, cardiovascular or neuro-syphilis – range of
infection
• Congenital syphilis – stillbirth
• Treatment – penicillin, erythromycin OR
doxycycline
Chlamydial infection
• Asymptomatic majority
• Symptoms and complications similar to gonorrhea
• Conjunctivitis - in newborn – vertical transmission
• Sterility in women
• Urethritis, epididymis – men
• Treatment – azithromycin or doxycycline
Trichomoniasis
• Parasitic infection
• Vaginitis and vaginal discharge
• Men – usually asymptomatic – urethritis
• Adverse outcome in pregnancy – low BW, premature rupture of
membrane
• Treatment – metronidazole or tinidazole
Chancroid
• Small papule at site of inoculation – 2 to 3
days – erodes –ulcer
• Extremely painful ulcer and deep
• 25% patients – inguinal lymph nodes
• Treatment – ciprofloxacin, erythromycin,
ceftriaxone, azithromycin
Lymphogranuloma venereum
• Swelling of lymph nodes in groin
• Small painless ulcer in genetalia -2 to 3 days – disappear
• Untreated –> lymphatic damage –> elephantiasis of genetalia
• Treatment – doxycycline, erythromycin, tetracycline
• Surgical correction for strictures
Donovanosis
• Small papules – ruptures to form granulomatous lesion – painless
• Bleeds on contact
• Treatment – azithromycin, doxycycline
Genital herpes
• Herpes simplex type 2
• Papular lesions – multiple blisters – ulcers –
painful
• No cure
• Antivirals like acyclovir to reduce the severity
and pain
• Four to five episodes per year
• Acyclovir, valaciclovir, famciclovir
Human papilloma virus
• Ano-genital warts
• Cervical cancer in female
• Treatment for large lesions
• Cancer screening for women – pap smear, colposcopy etc
• Prevention in sexually active younger population
• vaccination
Control of STDs
• AIM – prevention of ill health
• Primary prevention
• Secondary prevention
• Control depends on
• 1. Initial planning
• 2. Intervention strategies
• 3. Support components
• 4. Monitoring and evaluation
Initial planning
• Problem definition
• Establishment of priorities – age, sex, addiction
• Setting objectives
• Considering strategies
Intervention strategies
• Case detection
• Screening
• Contact tracing
• Cluster testing
• Case holding and treatment
• Epidemiological treatment – contact treatment
• Personal prophylaxis – contraceptives, vaccination
• Health education
Support components
• STD clinic – integrate with PHC, facility for treating women
separately
• Laboratory services
• Primary health care
• Information system
• Clinical/laboratory/sentinel notification needed
• Legislation – immoral traffic 1986 for both sex – exploited
sexually for commercial purpose
• Social welfare measures – rehabilitation of prostitutes, decent
living conditions, prohibition of pornographic books and pictures
etc.,
THANKYOU

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Hiv and std

  • 1. HIV • Acquired Immuno Deficiency Syndrome (AIDS) • Fatal illness • Caused by a retrovirus HIV • It breaks down the body's immune system, leaving the patient vulnerable to a host of life threatening opportunistic infections, neurological disorders or unusual malignancies.
  • 2. EPIDEMIOLOGY • AGENT: HIV – HUMAN IMMUNO DEFICIENCYVIRUS • AttacksT4 lymphocytes – Replicates inside it and destroy it • Pass through blood brain barrier • Two types – HIV1 and HIV2 • RESERVOIR: Cases and Carriers • SOURCE: • High concentration – blood, semen and CSF • Lower concentration in other body fluids like saliva, urine etc
  • 3. • HOST FACTORS: • AGE – 20-49 most common • SEX – more among homosexuals, Multiple partners, Prostitutes
  • 4. Mode of transmission • SexualTransmission • Blood contact – blood transfusion, needle injury like ear piercing, tattooing etc • Mother to child transmission
  • 5. • INCUBATION PERIOD: • Few months to 10 years or more • CLINICAL MANIFESTATION: • Initial Infection with virus and antibody development • Asymptomatic carrier state • AIDS –related complex (ARC) • AIDS
  • 6.
  • 7. DIAGNOSIS • ELISA - Screening test for HIV – detect antibodies • Western Blot test – Confirmatory – Detect more specific antibody to viral core protein
  • 8. CONTROL OF AIDS • PREVENTION 1. Education 2.Combination HIV prevention 1. Biomedical 2.Behavioural 3. Structural interventions 3. Prevention of blood borne transmission
  • 9. • ANTIRETROVIRAL TREATMENT: • Nucleoside reverse transcriptase inhibitors (NRTIs) • Nucleotide reverse transcriptase inhibitors (NtRTIs) • Non-Nucleoside reverse transcriptase inhibitors (NNRTIs) • Protease inhibitors (PPs) • Integrase strand transfer inhibitors (INSTIs)
  • 10.
  • 11. STD • Group of communicable diseases • Transmitted predominantly by sexual contact • Caused by viral, bacterial, protozoan, fungi and ectoparasites • Previously venereal disease (VD) – 5 diseases • Syphilis, gonorrhea, chancroid, LGV and donovanosis • Now STD – more than 20 agents
  • 12. Epidemiological determinants AGENT • Nisseria gonorrhoeae • Treponema pallidum • Haemophilus ducreyi • Chlamydia trachomatis • Calymmatobacterium granulomatis • Herpes simplex virus • Hepatitis B • HPV • HIV • Molluscum contagiosum • Candida albicans • Trichomonas vaginalis
  • 13. Host and demographic factors • Age – 20-24 years • Sex – morbidity male > female, severity female>male • Marital status – single, divorced, separated • SES – low SES • Increased population – more younger population • Rural to urban migration • Delaying in female marriage
  • 14. Social factors • Prostitution • Broken homes • Sexual disharmony • Easy money • Emotional immaturity • Urbanization • Social disruption - war • International travel • Changing behavior pattern • Social stigma • Alcoholism
  • 15. Clinical spectrum • Gonococcal infection • Inflammation – urethra and rectum in male, cervix and rectum in female • Complications – PID – ectopic pregnancy, infertility, chronic pelvic pain • In men – epididymis • Treatment – cefixime, ciprofloxacin
  • 16. Syphilis • Ulceration of urogenital tract, mouth or rectum • Skin eruptions, cardiovascular or neuro-syphilis – range of infection • Congenital syphilis – stillbirth • Treatment – penicillin, erythromycin OR doxycycline
  • 17. Chlamydial infection • Asymptomatic majority • Symptoms and complications similar to gonorrhea • Conjunctivitis - in newborn – vertical transmission • Sterility in women • Urethritis, epididymis – men • Treatment – azithromycin or doxycycline
  • 18. Trichomoniasis • Parasitic infection • Vaginitis and vaginal discharge • Men – usually asymptomatic – urethritis • Adverse outcome in pregnancy – low BW, premature rupture of membrane • Treatment – metronidazole or tinidazole
  • 19. Chancroid • Small papule at site of inoculation – 2 to 3 days – erodes –ulcer • Extremely painful ulcer and deep • 25% patients – inguinal lymph nodes • Treatment – ciprofloxacin, erythromycin, ceftriaxone, azithromycin
  • 20. Lymphogranuloma venereum • Swelling of lymph nodes in groin • Small painless ulcer in genetalia -2 to 3 days – disappear • Untreated –> lymphatic damage –> elephantiasis of genetalia • Treatment – doxycycline, erythromycin, tetracycline • Surgical correction for strictures
  • 21. Donovanosis • Small papules – ruptures to form granulomatous lesion – painless • Bleeds on contact • Treatment – azithromycin, doxycycline
  • 22. Genital herpes • Herpes simplex type 2 • Papular lesions – multiple blisters – ulcers – painful • No cure • Antivirals like acyclovir to reduce the severity and pain • Four to five episodes per year • Acyclovir, valaciclovir, famciclovir
  • 23. Human papilloma virus • Ano-genital warts • Cervical cancer in female • Treatment for large lesions • Cancer screening for women – pap smear, colposcopy etc • Prevention in sexually active younger population • vaccination
  • 24. Control of STDs • AIM – prevention of ill health • Primary prevention • Secondary prevention • Control depends on • 1. Initial planning • 2. Intervention strategies • 3. Support components • 4. Monitoring and evaluation
  • 25. Initial planning • Problem definition • Establishment of priorities – age, sex, addiction • Setting objectives • Considering strategies
  • 26. Intervention strategies • Case detection • Screening • Contact tracing • Cluster testing • Case holding and treatment • Epidemiological treatment – contact treatment • Personal prophylaxis – contraceptives, vaccination • Health education
  • 27. Support components • STD clinic – integrate with PHC, facility for treating women separately • Laboratory services • Primary health care • Information system • Clinical/laboratory/sentinel notification needed
  • 28. • Legislation – immoral traffic 1986 for both sex – exploited sexually for commercial purpose • Social welfare measures – rehabilitation of prostitutes, decent living conditions, prohibition of pornographic books and pictures etc.,