X-rays are a form of electromagnetic radiation that are produced when fast moving electrons collide with a metal target in an x-ray tube. There are two types of x-rays produced: bremsstrahlung and characteristic. An x-ray tube consists of a cathode, anode, focusing cup, and glass housing within an evacuated envelope. Electrons are emitted from the heated cathode and accelerated towards the anode, where their energy is converted upon impact to produce x-rays. The design and construction of x-ray tubes aims to efficiently produce x-rays for diagnostic imaging while withstanding heavy workload.
Interactions of X-ray & matter & Attenuation - Dr. Sayak DattaSayakDatta
Slideshow on Radio-physics covering different interactions between X-ray and matter along with Attenuation. It includes Photo-electric effect, Compton scatter, Coherent scatter, Attenuation of Monochromatic & Polychromatic radiation, Diagnostic Xray applications, Scatter radiations.
Interactions of X-ray & matter & Attenuation - Dr. Sayak DattaSayakDatta
Slideshow on Radio-physics covering different interactions between X-ray and matter along with Attenuation. It includes Photo-electric effect, Compton scatter, Coherent scatter, Attenuation of Monochromatic & Polychromatic radiation, Diagnostic Xray applications, Scatter radiations.
In this lecture, we will be talking only about the interaction of an ionizing electromagnetic radiation with matter, specifically about the interaction of X-Rays with the matter
Note: Gamma rays interact with the matter by the same way that X-rays interact with matter. In this lecture, we just focused on X-rays to complete our previous lecture about the production of X-rays
In this lecture, we will be talking only about the interaction of an ionizing electromagnetic radiation with matter, specifically about the interaction of X-Rays with the matter
Note: Gamma rays interact with the matter by the same way that X-rays interact with matter. In this lecture, we just focused on X-rays to complete our previous lecture about the production of X-rays
THIS IS A PRESENTATION ON TRANSMISSION ELECTRON MICROSCOPY .(APART FROM DIFFERENT BOOKS,I HAVE ALSO TAKEN INFORMATION FROM DIFFERENT WEBSITES & PRESENTATIONS AVAILABLE IN NET ..
In this pdf you will learn how the x ray machines work and how x rays produce, to enhance your knowledge about x rays machine then you have read this. You will get every knowledge about xrays in short and easy language.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
3. INTRODUCTION
X-RAYS ARE FORM OF HIGH ENERGY ELECTROMAGNETIC
RADIATION AND PART OF ELECTROMAGNETIC SPECTRUM
WITH WAVELENGTH SHORTER THAN VISIBLE LIGHT . MOST
OF X-RAYS HAVE A WAVELENGTH RANGING FROM 0.03 TO 3
NANOMETER .
4. HISTORY OF DISCOVERY OF X-RAY
X-RAYS WERE DISCOVERED BY GERMAN PHYSICIST WILHELM
CONRAD ROENTGEN , ON 8th NOV 1895 . WHEN HE WAS
INVESTIGATING THE CONDUCTION OF ELECTRICITY
THROUGH GASES AT LOW PRESSURE IN GLASS TUBES .
5. PROPERTIES OF X-RAYS
• X-RAYS ARE ELECTROMAGNETIC RADIATION OF SHORTER
WAVELENGTH .
• THEY TRAVEL IN STRAIGHT LINE WITH A VELOCITY OF
LIGHT .
• X-RAYS PRODUCE CHEMICAL CHANGES IN SUBSTANCES
THROUGH WHICH THEY PASS .
• X-RAYS PENETRATE THROUGH SUBSTANCES THAT ARE
OPAQUE TO VISIBLE LIGHT .
6. PRODUCTION OF X-RAY
WHEN THE FAST MOVING ELECTRONS STOPPED BY THE
TARGET (ANODE) THE KINETIC ENERGY OF THE
ELECTRONS WILL BE CONVERTED INTO X-RAYS .
BASED ON THEIR WAY OF PRODUCTION , X-RAYS ARE OF
TWO TYPES :
(a)BREMSSTRAHLUNG RADIATION .
(b)CHARACTERISTIC X-RAYS .
7. BREMSSTRAHLUNG X-RAYS
THE BREMSSTRAHLUNG IS A GERMAN WORD MEANING
BREAKING RADIATION . THE ELECTRON WHILE PASSING
NEAR THE NUCLEUS MAY SUFFER A SUDDEN DEFLECTION
AND ACCELERATION BY THE ACTION OF COULOMB FORCES
OF ATTRACTION . AS A RESULT , THE ELECTRONS MAY LOSE
THEIR KINETIC ENERGY , IN THE FORM OF
BREMSSTRAHLUNG X-RAYS .
9. CHARACTERISTIC X-RAYS
ELECTRON INCIDENT ON A TARGET MAY PRODUCE CHARACTERISTIC
X-RAYS. AN ELECTRON WITH KINETIC ENEGY E0 MAY INTERACT WITH
THE ATOMS OF THE TARGET, BY EJECTING AN ORBITAL ELECTRON
FROM THE K SHELL. NOW, THERE IS VACANCY IN THE K SHELL AND
THE ATOM IS SAID TO BE IONIZED. THE OUTER ORBITAL ELECTRONS
(FROM M OR L SHELL) WILL FELL DOWN TO FILL THE VACANCY IN THE
K SHELL. IN DOING SO, THE DIFFERENCE IN BINDING ENERGY OF
THE TWO SHELLS IS IRRADIATED IN THE FORM OF X-RAY PHOTONS
WHICH ARE KNOWN AS CHARACTERISTIC X-RAYS.
11. X-RAY TUBE DESIGN & CONSTRUCTION
X-RAY TUBE – IT IS ELECTRICAL DEVICE WHICH CONTAINS ALL
THE ESSENTIAL COMPONANTS REQUIRED FOR PRODUCTION OF
X-RAYS, WITH IN AN EVACUATED GLASS/METALLIC ENVELOPE.
12. COMPONENTS OF X-RAY TUBE
COMPONENTS OF X-RAY TUBE – THE X-RAY TUBE IS CONSISTS
OF FOLLOWING ELEMENTS :-
CATHODE
ANODE
FOCUSING-CUP
GLASS HOUSING
13. CATHODE
CATHODE IS -VE TERMINAL OF AN X-RAY TUBE.
IT IS CONSIST OF A FILAMENT (SOURCE OF e-), CONNECTIVE WIRES ( FOR POWER SUPPLY) &
A METALLIC FOCUSING CUP.
THE W74 FILAMENT IS 0.2 cm IN DAIMETER & 1cm OR LESS IN LENGTH.
ELECTRONS ARE PRODUCED FROM CATHODE BY “THERMOIONIC EMISSION”.
SUPPLY OF CURRENT TO THE FILAMENT ∝ PRODUCTION OF ELECTRONS FROM FILAMENT
FILAMENT &
FOCUSING CUP
14. ANODE
ANODE IS THE +VE TERMINAL AND SERVES AS TARGET FOR THE ELECTRONS EMMITED
FROM CATHODE
ANODE SHOULD HAVE FOLLOWNG PROPERTIES :-
HIGH ATOMIC NUMBER.
HIGH MELTING POINT.
HIGH SPECIFIC HEAT & THERMAL CONDUCTIVITY.
LOW VAPOUR PRESSURE EVEN AT HIGH TEMPERATURE.
CONVENIENT FOR MECHANICAL CONSTRUCTION.
TUNGSTEN IS THE METAL OF CHOICE FOR
ANODE BECAUSE OF IT’S HIGH ATOMIC
NUMBER (74) AND A HIGH MELTING POINT
ABOUT 3370ºC.
ANODE (ROTATING TYPE)
15. FOCUSING CUP
THE FOCUSING CUP IS MADE UP OF MOLYBDENUM (MO).
IT IS A METAL CUP IN WHICH THE CATHODE OF AN X-RAY TUBE IS
MOUNTED.
THE CATHODE CUP CONTROLS THE WIDTH OF ELECTRON
DISTRIBUTION, DIRECT THE ELECTRONS TOWARDS THE TARGET.
FOCUSING CUP OF X-RAY
TUBE( WITH OTHER
COMPONENTS)
16. GLASS HOUSING
THE ANODE & THE CATHODE ARE ENCLOSED IN A BOROSILICATE GLASS
ENVELOPE CONTAINING A VACUUM, BECAUSE GAS IN THE TUBE WILL PROVIDE
RESISTANCE TO THE ELECTRONS.
FUNCTIONS OF GLASS HOUSING:-
IT PROVIDES AN ATTACHMENT SURFACE FOR THE COLLIMATORS
IT CONTAINS COOLING OIL FOR HEAT DISSIPATION
IT SHIELDS AGAINST THE STRONG X-RAYS (INHERENT FILTERATION).
IN ROATATING ANODE TYPE TUBE, IT CONTAINS ANODE ROTATION POWER
SOURCE.
GLASS HOUSING
17. CONCLUSION
THE QUALITY OF X-RAYS AND THE BASIC TUBE DESIGN AND
CONSTRUCTION ARE DEPENDS ON OUR NEEDS SUCH AS THE
QUALITY IMAGING, WORKLOAD AND DURABILIYY OF THE
INSTRUMENTS BEING USED. ALTHOUGH THE BASIC METHOD OF
PRODUCTION OF X-RAYS IS STIL SAME BUT SOME ADVANCEMENTS
AND MODIFICATION IN PRODUCTION OF X-RAYS AND INSTRUMENT
DESIGN HAS CAME INTO EXISTANCE FOR BETTER PERFORMANCE OF
THE X-RAY TUBE AND TO IMPROVE THE OF QUALITY IMAGES TO
BRING PRECESION IN RADIODAIGNOSIS.