The control console allows the technologist to set technical factors like mAs and kVp and make exposures. It contains meters to measure kVp, mA, and exposure time. The console has several circuits including high voltage, filament, and primary circuits. Automatic exposure control uses an ion chamber or photodiode to automatically terminate the exposure when the proper optical density is reached on the image receptor. High voltage generation converts line voltage to kilovolts needed for x-ray production using transformers and rectifiers.
This presentation is about control of kv and ma in x-ray circuit, it includes different components of X-ray imaging system (operating console , high voltage generator and X-ray tube ). high voltage generator and high frequency generator is well explained along with step up ,step down and an auto transformer .
This presentation is about control of kv and ma in x-ray circuit, it includes different components of X-ray imaging system (operating console , high voltage generator and X-ray tube ). high voltage generator and high frequency generator is well explained along with step up ,step down and an auto transformer .
Webinar Slides: Measurements and Analysis for Switched-mode Power Designsteledynelecroy
This webinar covers the measurements of interest for designers of switched-mode power conversion circuits and devices. With the goal of high efficient and reliable designs, we review the acquisition of voltage and current, their relationship in switched-mode power conversion circuits.
We review specific power circuit performance areas including the analysis of power device switching losses, conduction losses, dynamic on-resistance, control loop response, power quality, conducted emissions, best practices for probing power circuits, and power rail integrity measurements.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
2. Bucky slot cover
During fluoroscopy the Bucky tray is
moved to the end of the table
This leaves an opening in the side of the
table about 5cm
Approximately at what level is the bucky?
3. Bucky slot cover
• The opening should
automatically be
covered with at least
0.25 mm Pb equiv..
5. The Control Console
• The control console is
device that allows the
technologist to set
technical factors (mAs
& kVp) and to make
an exposure.
• Only a legally
licensed individual is
authorized to
energize the console.
6. Control Panel
• All the electric circuits connecting the meters
and controls are at low voltage to minimize the
possibility of shock.
7. Operating Console
Controls:
Line Compensation, kVp, mA and time
Quantity = # of x-rays
Milliroentges (mR) or (mR/mAs)
Quality = the pentrability
Kilovolts peak (kVp)
8. Operating Console has
meters to measure
kVp, mA, & exposure time
Modern units only display mAs
Units with ACE’s will have a separate
meter for mAs
10. AEC
Automatic Exposure Control
Uses an ionization chamber
Technologist sets kVp, mA, back-up
time & sensors
Exposure terminates the IR has proper
OD
Patient positioning must be absolutely
accurate
12. APR
Anatomically Programmed Radiography
(Ch 15)
Radiologic Technologist selects on the
console a picture or a written
description of the anatomic part to be
imaged and the patient body habitus
A computer selects the appropriate
kVp and mAs.
13. APR
The whole process uses an AEC
Precise patient positioning over the
phototiming sensor is critical
20. Line Compensation
Most imaging systems are designed to operate
on 220 V. (some 110 V or 440 V)
However power from the wall is not always
accurate continuously
21. Line Compensation
Wired to the autotransformer is the line
compensator
Designed to maintain the accurate
voltage required for consistent production
of high-quality images
Today’s line compensators are automatic
and are not displayed on the control panel
23. Autotransformer
The power for the x-ray imaging system
is delivered first to the autotransformer
The autotransformer works on the
principle of electromagnetic induction
It has one winding and one core
There are a number of connections along
its length
24. Autotransformer
• A’s = primary
connections &
power into the
transformer
• Other connections
allow for variations
of voltages
25. Autotransformer
Is designed to step up voltage to about
twice the input voltage value
The increase in voltage is directly related
to the number of turns
27. X-ray tube current or
Filament circuit
A separate circuit crossing from cathode
to anode
Measured in milliampers (mA)
What determines how many x-rays are
created?
28. X-ray tube current or
Filament circuit
# of e- is determined by the temperature
of the filament. The hotter the filament
the more e-
Are their any limiting factors to thermionic
emission?
33. Exposure Timers
The timer circuit is separate from the other
main circuits of the imaging system
It is a mechanical or electronic device
whose action is to “make” and “break” the
high voltage across the x-ray tube
This is done on the primary side of the high
voltage transformer.
34. mAs Timers
Monitors the product of mA and exposure
time
Terminates the exposure when the
desired mAs value is reached
Located on the secondary side of the
high-voltage transformer since actual
tube current must be monitored
35. mAs Timers
Designed to proved the highest mA for
the shortest exposure
Modern X-ray machines have falling-load
generator
Automatically adjusts to the highest mA at
the shortest exposure time possible
36. AEC Control
AEC measure the quantity of radiation
reaching the IR
Automatically terminates when the IR has
received enough radiation for desired OD
Two types are common
37. Flat, parallel plate
ionization chamber
Located between the patient and the IR
Made radiolucent
Ionization w/in the chamber creates a
charge; calibrated to produce a given OD
on the IR
38. Photomultiplier (Photodiode)
detector assembly
Located behind the IR
Contains a fluorescent screen and a
photomultiplier
The photomultiplier detects the light from
the fluorescent screen until the desired
OD on the IR is reached terminating the
exposure
39.
40. AEC’s
Upon instillation must be calibrated by
the service engineer
Technologists selects the desired OD
which then sets the mA & kVp
41. AEC’s
A back up timer usually automatically set
to prevent over exposure if the AEC fails
Should be set to 1.5 times the expected
exposure time Why?
When the ionization chamber or
photodiode reaches the preset level, a
signal is returned to the operating
console to terminate the exposure
42. High-Voltage Generator
Responsible for increasing the output
voltage from the autotransformer to the
kVp necessary for x-ray production
3 parts: High-voltage transformer (step-
up), filament transformer (step-down) and
rectifiers
43. High voltage transformer
Or step up transformer
Connected to the Major and Minor kVp
selector
Increases the volts from the
autotransformer to kilovolts
45. Voltage Rectification
Converts AC to DC current
During the negative cycle current can
only flow from anode to cathode
E- must travel cathode to anode – DC
current keeps e- traveling in the correct
direction, cathode to anode
Attracted to the positive anode
49. High-Voltage Generation – converts
220 volts of AC to kilovolts of DC
The generator is a FIXED component of
the imaging system, not under the
control of the technologist
Three basic types: single phase, three
phase, and high frequency
The generator affects the quality and
quantity of photons produced