The document defines wounds and classifies them into different types such as lacerated, incised, punctured, and contaminated wounds. It also discusses the phases of wound healing which include inflammatory, proliferative, and remodeling phases. Factors that affect wound healing include blood supply, nutrition, lifestyle, medications, and infection status which should be considered in managing patients with wounds.
Proper wound care is necessary to prevent infection, assure there are no other associated injuries, and to promote healing of the skin. An additional goal, if possible, is to have a good cosmetic result after the wound has completely healed. This wound care article is designed to present information on wounds involving mainly the skin; it is not meant to cover all wounds (for example, gunshot, degloving wounds, tendon lacerations, and others).
This contains wound and wound dressing,classification of wound,
signs and symptoms of wound
Diagnostic evaluation od wound
Wound healing process,
Factors affecting wound healing
Complication of wound
Wound Dressing
Types of dressing
Articles need in wound dreassing
Proper wound care is necessary to prevent infection, assure there are no other associated injuries, and to promote healing of the skin. An additional goal, if possible, is to have a good cosmetic result after the wound has completely healed. This wound care article is designed to present information on wounds involving mainly the skin; it is not meant to cover all wounds (for example, gunshot, degloving wounds, tendon lacerations, and others).
This contains wound and wound dressing,classification of wound,
signs and symptoms of wound
Diagnostic evaluation od wound
Wound healing process,
Factors affecting wound healing
Complication of wound
Wound Dressing
Types of dressing
Articles need in wound dreassing
wound management briefing training course including wounds, wound healing & wound types, wound closure, wound covers, wound dressings and marketing plan for new product launch, wound assessment types and measures.
for HCP , wound care specialists, nursing, and wound care and health associations
ABDUL MANAN BIN OTHMAN
BSc (Hons) NPD Northumbria UK, CCWC (Mal)
Assistant Medical Officer
National Wound Care Committee
Wound Care Clinician
Kota Tinggi District Health Office
wound management briefing training course including wounds, wound healing & wound types, wound closure, wound covers, wound dressings and marketing plan for new product launch, wound assessment types and measures.
for HCP , wound care specialists, nursing, and wound care and health associations
ABDUL MANAN BIN OTHMAN
BSc (Hons) NPD Northumbria UK, CCWC (Mal)
Assistant Medical Officer
National Wound Care Committee
Wound Care Clinician
Kota Tinggi District Health Office
this a basic presentation which I got inspired to do after seeing some presentations made on slideshare. It basically covers types of wounds,wound healing process,factors affecting wound healing and wound care.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
2. Define wounds
Classify wounds
Explain the healing process
Discuss Factors that affect wound healing
Describe the management of patients with
wounds
3. A wound is just an injury to an organ or
tissue of the body that results in a disruption
of the normal continuity of that organ or
tissue.
or
A wound is a cut or break in the continuity of
any tissue caused by injury or operation.
4. Lacerated wound: This that type of injury that
has rough or jagged edges e.g. that which is
sustained in an RTA, barbed wire injury etc.
Incisional wounds: These are types of
injuries made by sharp objects. They have
edges that are evenly separated e.g. those
wounds made by surgeons during surgery.
5. Punctured wounds: These are wounds that
are caused by sharp pointed objects causing
a small opening through the skin. These are
commonly caused by such objects such as
nails, knives, gun shots etc. they appear small
superficially but involving deeper structures
such as nerves, blood vessels or viscera
which may be damaged and contamination
carried into deeper tissues.
6. Contused wounds: These are a type of wounds
that involve superficial injuries without damage
to the skin surface. They are commonly caused
by blunt surface forces and are characterized by
a considerable soft pad. These are known
common causes of haematomas(collection of
blood outside the blood vessels).
Poisoned wounds: These wounds are those type
of wounds that involve direct contamination by
the source of the injury such as snake bites,
insect bites, dog bites especially where rabies
organisms exists.
7. Concussions: These are a type of wounds that
result from vigorous shaking such as the
severe shaking of the head causing brain
function derangement without structural
damage.
Abraisions: These are wounds that result
from rubbing a body tissue especially the
skin against a rough surface leading to loss
of superficial tissue due to friction. These are
characteristically painful and superficial.
8. Contaminated Wounds
These are wounds which are exposed to
excessive amounts of bacteria. These wounds
have a higher risk of infection e.g.
unprepared colon surgery, dirty laceration
etc.
Infected Wounds
These are wounds that have infected material
in them. They usually have pus or slough on
their surfaces. Common infecting organisms
include streptococci, staphylococci etc.
9. Clean Wounds
These are wounds that have been rendered
clean by cleaning with the use of
disinfectants such as savlon, povidone iodine,
methylated spirit, etc.
Debrided Wounds
These are wounds whose top infected
(necrotic tissue and pus) tissue has been
removed surgically by a process known as
SLOUGHECTOMY or DEBRIDEMENT.
10. PHASES OF WOUND HEALING FIRST PHASE
INFLAMMATORY PHASE-starts immediately
after injury and lasts 3-6 days or 4-6 days.
2 major processes occur during this phase …
HEMOSTATIS AND PHAGOCYTOSIS
Hemostatis- blood vessels constrict,
platelets aggregates and bleeding stops,
scabs forms, preventing entry of infectious
organisms
11. phagocytosis
Inflammation-increase blood flow, to wound
resulting localized redness and edema,
attracts WBC and wound growth factors.
WBC arrive-clear debris from wound.
12. SECOND PHASE PROLIFERATIVE PHASE
extends from day 3 to about 21 day post
injury. collagen synthesis , establishment of
new capillaries ,creation of granulation tissue
, wound contraction , epitheliazation.
THIRD PHASE REMODELLING OR MATURATION
PHASE -final healing stage may continue for I
year or more. Remodeling of scar tissue to
provide wound strength.
13. FIRST INTENTION HEALING
partial thickness wounds. a clean incision is
made with primary closure, minimal scarring
expected when the edges of clean surgical
incisions are sutured together, tissue loss is
minimal or absent if the wound is not
contaminated with microorganism. -e.g.-
abrasion or skin tear.
14. SECOND INTENTION HEALING
granulation accompanies traumatic open
wounds with tissues loss or wounds with a
high microorganisms count.Go through a
process involving scar tissue formation, heal
slowly because of the volume of tissue
needed to fill the defect. -e.g.-contaminated
surgical wound, pressure ulcer
15. Healing By Third Intention or Secondary Suture
Also called healing by Tertiary Intention is a
type of wound healing which occurs when
there is delayed suturing of a wound or if
there is a breakdown of the initial suture with
massive infection and loss of tissue. Two
opposite granulation tissues are brought
together with the result of a deeper wider scar.
16. Developmental considerations (healthy
children and adults)
Blood supply
Nutrition
Lifestyle
Medications
Contamination and infection
17. As a wound heals many elements such as
adequate nutrition, cleanliness, rest, and
position determine how quickly the process
occurs. Although post operative dressings are
initially changed by a member of the surgical
team, subsequent dressing changes in the
immediate post operative period are usually
done by a nurse.
18. A dressing is applied to a wound for one or
more of the following reasons;
To provide a proper environment for wound
healing
To absorb excessive drainage
To splint or immobilise the wound
To protect new epithelial tissue from
mechanical injury
19. To protect the wound from bacterial
contamination and from soiling by faeces,
vomitus, and urine etc.
To promote haemostasis, as in a pressure
dressing
To provide mental and physical comfort of
the patient
20. Wound dressing is done according to the
immediate assessment, the state of the
wound, and objective of the surgeon
concerned. Thus dressings may be described
as;
Wet dressings
Moisture retentive dressings
Occlusive dressings
Pressure dressings
Medicated dressings
21. HEMORRRHAGE -risk of hemorrhage is greatest
during the first 48 hours after surgery .it is an
emergency
INFECTION -surgical infection is apparently 2-11
days post operatively. Observe for presence of
changed in wound color, pain or drainage-culturing
of the wound.
DEHISCENCE WITH POSSIBLE EVISCERATION -may
occur 4-5 days postoperatively. -involves an
abdominal wound in which the layers below the skin
separates. Observe for an increase in flow of
serosanguinous drainage into the dressing can
indicate impending dehiscence
22. Wound are as a result of trauma to tissues
Their severity depends on the trauna
sustained to the tissue .
You need to understand the classification of
wound in order to manage them .
Understanding the factors promoting and
delaying wound healing will be of importance
in the management of wounds
23. What is a wounds ?
Mention 5 types of wounds
List 4 factors affecting wound healing.
What are the phases of wound healing?
24. Miss Catherine Chanda aged 28 years old sustained
burns of the anterior trunk, posterior trunk and left
leg. She has developed some inflammation and the
attending Doctor admitted her to female surgical
ward where you working from.
1. Explain two (2) types of inflammation
10%.
2. Explain the pathophysiology of inflammation.
20%
3. Discuss the nursing care of Ms. Chanda
during her stay in hospital. 50%
4. Outline five (5) complications that Ms Chanda
may develop 20%