The document discusses the significance of molecular hydrogen in water, highlighting a pivotal study published in 2007 that revealed its therapeutic benefits. It addresses common misconceptions about hydrogen water, its safety, and its potential health advantages, supported by numerous scientific studies. The text emphasizes that while hydrogen is not very soluble in water, its therapeutic effects have been documented at specific concentrations.

1. What caused us to believe in our water?

2. The ‘BIG EVENT’ that changed
everything about our industry.

3. In 2007 the first scientific study of molecular hydrogen in water was
published in ‘Nature’, the US scientific journal.
It demonstrated the therapeutic benefits of H2 reported by
scientists at Nagoya University, Japan.
It changed the whole understanding of how our water works in the body.

4. 2016
400 studies
2103
120 studies
2007
One study
+ 150 Disease-specific studies

6. MAJOR THERAPEUTIC FINDINGS
Selective Antioxidant
Inflammation support
Allergy support
Apoptosis support
Cell signalling support

7. MOLECULAR HYDROGEN:
“WE DON’T KNOW WHY IT WORKS.
WE JUST KNOW IT WORKS”.
DR. SHIGEO OHTA, PHD.

8. Frequently asked questions
•What is hydrogen water?
•Isn’t hydrogen gas explosive?
•Water is H2O. Doesn’t water already have hydrogen in it?
• If water is “hydrogen rich”, isn’t it acidic?
• I read that if you add hydrogen to water, then it makes hydrogen peroxide?
•Hydrogen gas doesn’t dissolve very well in water, so how can there even be enough
for it to be beneficial?
•Won’t any dissolved hydrogen gas immediately escape out of the water?
•How much hydrogen water should I drink to get the benefits?
•Does more hydrogen equal more benefits?
• Is hydrogen safe?
• When was hydrogen’s therapeutic benefits first discovered?
I heard that drinking alkaline water can neutralize excess acid.
•I heard that “every sick person as an acidic blood pH”. Is this true?
• I heard that Dr. Otto Warburg won the Noble Prize for proving that “the root cause
of all cancer is too much acidity in the body and low oxygen levels”. Is this true?
ANSWERS ON FOLLOWING PAGES

9. Frequently asked questions
What is hydrogen water?
Hydrogen water or hydrogen-rich water (also called hydrogen-enriched
water) simply means normal water (H2O) that contains dissolved hydrogen
gas (H2). For example, there are carbonated waters or beverages (soda
pop), which contain dissolved carbon dioxide gas (CO2), or oxygen water,
which contains dissolved oxygen gas (O2). Similarly, you can have water that
contains dissolved hydrogen gas.
Think of it this way: you can make hydrogen water by taking a tank of
hydrogen gas (just like tanks of helium used to fill balloons or tanks of
oxygen gas used in hospitals), and bubbling it into a glass of water. There are
also many other methods to make hydrogen water, but this may help you
better understand what hydrogen water is. It is simply water that contains
dissolved hydrogen gas.

10. Frequently asked questions
Isn’t hydrogen gas explosive?
Yes, it is VERY explosive.
Hydrogen is the most energy-dense molecule by mass.
However... when the gas is dissolved in water it is not explosive at
all.
It’s just like mixing gunpowder in water. It wouldn’t be explosive
either. Even when it is in the air, it is only flammable above a 4.6%
concentration by volume, which is not a concern when talking about
hydrogen-rich water.

11. Frequently asked questions
Water is H2O. Doesn’t water already have hydrogen in it?
The water molecule has two hydrogen atoms, chemically bound to the oxygen atom. This is
different from the hydrogen gas molecule (H2), which is just two hydrogen atoms bound only to
each other.
Here’s an example: we need oxygen (O2) to live, so why can’t we just get our oxygen from drinking
water H2O? The oxygen is chemically tied up in the water molecule.
We need available oxygen gas, (O2) that is not bonded to other atoms or molecules. By the same
token, we need the available hydrogen gas (H2).
This is why water is not explosive or doesn’t burn. Although it contains hydrogen, which is
flammable, and oxygen, which fire needs to burn, the hydrogen and oxygen are bonded together
to form water (H2O). Thus, water is not flammable-in fact, H2O is what we use to extinguish fires.
Furthermore, virtually everything has hydrogen atoms in it, but those hydrogen atoms are
chemically tied up with other things. For example, a water molecule has two hydrogen atoms
that are chemically tied up with the oxygen. Or, a sugar molecule like glucose contains 12
hydrogens, but those hydrogens are all bound to other carbon and oxygen atoms. In hydrogen
water, the hydrogen that is shown to be therapeutic is the available dissolved hydrogen in its
diatomic form, called molecular hydrogen.

12. Frequently asked questions
If water is “hydrogen rich”, isn’t it acidic?
If the water is rich in positive hydrogen ions (H+). then yes it IS acidic. But in
this case, we’re talking about neutral hydrogen gas, which is two hydrogen
atoms tied together.
It can be confusing to hear “hydrogen water” because we usually think of
hydrogen (meaning the hydrogen ion, H+) as acidic, and that is basically the
definition of pH. The p stands for potential or power, meaning a mathematical
exponent (in this case a logarithmic function), and the H stands for the
hydrogen ion, which is just a proton and no electron. So pH literally means the
logarithmic concentration of the hydrogen ion.
But when we say “hydrogen water” we are referring to dihydrogen or
molecular hydrogen, which is a neutral gas that is dissolved in the water.

13. Frequently asked questions
I read that if you add hydrogen to water, then it makes hydrogen
peroxide?
Water has the chemical formula H2O, and hydrogen peroxide has the
chemical formula H2O2, which by comparison contains an extra oxygen, not
hydrogen.
So it cannot form hydrogen peroxide.
The fact is, hydrogen gas does not bond to or react with the water molecules,
it just dissolves into the water. It does not create some novel molecule like
H4O, which would be chemically impossible to form anyway.
Hydrogen water and hydrogen peroxide are completely different things.

14. Frequently asked questions
Hydrogen gas doesn’t dissolve very well in water, so how can there even be enough for
it to be beneficial?
It is true that hydrogen is not very water soluble as it is a neutral, non-polar molecule
with a solubility of 1.6 mg/L, which is relatively low. But when we consider that
molecular hydrogen is the lightest molecule in the universe, we really need to compare
the number of molecules as opposed to the number of grams. For example, if a single
molecule weighed 2 mg (which is impossible, but used as an example), then having just
one of those molecules in a liter of water would give you 2 mg/L, but there would only
be one molecule. For reference, vitamin C (176.2 g/mole) weighs 88 times more than
hydrogen gas (2 g/mole). Therefore, hydrogen water at a concentration of 1.6 mg/L
would have more “antioxidant” molecules than 100 mg of vitamin C, as there are more
total molecules in 1.6 mg of hydrogen compared 100 mg of vitamin C. That is, 0.8
mmoles of H2 vs. about 0.6 mmoles of vitamin C.
But more importantly, hundreds of scientific studies clearly show that these
concentrations of hydrogen are effective.

15. Frequently asked questions
Won’t any dissolved hydrogen gas immediately escape out of the
water?
Yes, it does immediately start coming out of the water, but it doesn’t
just vanish immediately. Depending on the surface area, agitation, etc.,
the hydrogen gas can stay in the water for a few hours or longer before
it drops below a therapeutic level.
This is much like carbonated water or soda that contains carbon
dioxide gas (CO2), but because it does leave, it is best to drink the
water promptly before it goes “flat”.

16. Frequently asked questions
How much hydrogen water should I drink to get the benefits?
That is the same question scientists are asking and is still under
investigation.
Human studies generally provide about 1-3 mg/L of dissolved H2, and
these concentrations show significant health benefits.
If your water has a concentration of 1 mg/L (equivalent to 1 ppm, parts
per million), then two liters will give you 2 mg of H2. Although the
effective concentration for some people and some diseases may be
lower and/or higher, these doses are simply what have been seen to
exert benefits.

17. Frequently asked questions
Does more hydrogen equal more benefits?
Maybe, maybe not…. there is obviously a minimum required amount
needed to offer any health benefits, which may vary from person to
person.
It appears that you cannot get too much hydrogen, as it doesn’t build
up in your system.—you just exhale it out. In many cases there is a
clear dose-dependent effect, meaning the more hydrogen the better
or greater the effect. There are also many anecdotal reports that
suggest that consuming more hydrogen may offer even more benefits.
But more research needs to be done in this area.

18. Frequently asked questions
Is hydrogen safe?
Yes. Hydrogen gas has been shown to be very safe at concentrations hundreds of times
higher than what is being used for therapy. Here are a few examples:
Hydrogen’s safety was first shown in the late 1800s, where hydrogen gas was used to
locate gunshot wounds in the intestines. The reports showed that there were never any
toxic effects or irritation to even the most sensitive tissues.
Another good example of its safety is that hydrogen gas has been used in deep sea
diving since 1943 (at very high concentrations) to prevent decompression sickness.
Studies have shown no toxic effects from hydrogen when at very high levels and
pressures of 98.87% H2 and 1.26% O2 at 19.1 atm.
Furthermore, hydrogen gas is natural to the body because after a fibre-rich meal, our gut
bacteria can produce litres of hydrogen on a daily basis (which is yet another benefit
from eating fruits and vegetables).
Hydrogen gas is natural to our bodies, not like a foreign or alien substance that can only
be synthesized in a chemistry lab.

19. Frequently asked questions
When was hydrogen’s therapeutic benefits first discovered?
The earliest account of hydrogen gas having medicinal properties was
in 1798, for things like inflammation. But, it didn’t become a popular
topic among scientists until 2007, when an article about the benefits
of hydrogen was published in the prestigious journal of Nature
Medicine by Dr. Ohta’s group.

20. Frequently asked questions
I heard that drinking alkaline water can neutralize excess acid.
‘Alkaline water’ from a water ionizer is not a buffer and has low
alkalinity. It cannot neutralize very much acid.
Just a small amount of soda can easily lower the pH of a gallon of
alkaline water.
To help put this into perspective, consider that 1 tsp of baking soda
(sodium bicarbonate) can neutralize the same amount of acid as
10,000 liters of alkaline water at a pH of 10. This is a primary reason
why medical professionals have been skeptical about “alkaline ionized
water”. It simply wasn’t known that the benefit of this water is
attributed to the dissolved hydrogen gas until around 2007.

21. Frequently asked questions
I heard that “every sick person as an acidic blood pH”. Is this true?
Healthy blood pH varies between 7.35 to 7.45. Blood pH is tightly
regulated. In physiology, if someone has a blood pH of 7.1 they are
said to have acidosis even though 7.1 is actually alkaline according to
the pH scale. Very rarely do people ever get truly acidic blood
(pH<7.0). If the blood pH drops below 7, the body will not survive very
long. Therefore, virtually every sick person actually has an alkaline
blood pH even though some may have acidosis. Similarly, some
diseases can actually cause alkalosis (elevated blood pH). It is the
disease that causes the changes in blood pH, as opposed to the
changes in blood pH causing the disease. Of course, a low blood pH
can cause serious damage to the body and needs to be quickly
corrected.

22. Frequently asked questions
I heard that Dr. Otto Warburg won the Noble Prize for proving that
“the the root cause of all cancer is too much acidity in the body and
low oxygen levels”. Is this true?
No, it is not. Dr. Otto Warburg did do some cancer research and did make the
simple observation that once a cell becomes cancerous, it relies upon
glycolysis for its energy resulting in a higher production of acid.
He did NOT receive the Nobel Prize for proving that cancer can’t survive
without adequate oxygen or in an alkaline pH. In fact, his work shows that
cancer thrives just as well in an oxygenated environment that is alkaline as it
does under hypoxic/anaerobic conditions. In 1931, Otto Warburg received the
noble prize for his “discovery of the nature and mode of action of the
respiratory enzyme” now known as cytochrome oxidase, which transfers
electrons to oxygen during aerobic metabolism. In 1944, he was nominated for
a second Nobel prize for his discovery and work on flavoproteins used for
dehydrogenation reactions with their coenzymes.