Vocal cord paralysis current
         concepts



  Balasubramanian Thiagarajan
What has changed?

    Various hypothetical positions of vocal cord
    following paralysis – Not valid anymore

    More simplistic classification of vocal fold
    position

    All the theories accounting for vocal fold
    positions following paralysis are not
    accepted anymore
Vocal fold positions

    Abduction

    Adduction

    Midline
Current theory accounting for vocal vold
 position following vocal fold paralysis

    Type of lesion

    Pathology of lesion

    Synkinesis

    Fibrosis
Types of vocal fold palsy

    Unilateral recurrent laryngeal nerve palsy

    Isolated unilateral superior laryngeal nerve
    palsy

    Bilateral recurrent laryngeal nerve palsy

    Bilateral complete paralysis of vocal folds
Treatment algorithm of URLP
Role of speech therapy in URLP

    Controversial

    Does not hasten reinnervation

    Helps in breath support

    Helps psychologically

    Swallowing therapy is useful in pts with
    swallowing difficulty
Swallowing therapy

    Swallowing while holding the breath

    Push pull technique

    Hand clasp technique
Clinical examination (vocal)

    Glottic fry

    Hard glottal attacks

    Breathy voice

    Diplophonia

    Pitch breaks

    Phonation breaks

    Tense phonation
Glottic fry

    Creaky voice

    Cords vibrate slowly

    Pt feels as if breath has run out while
    speaking
Hard glottal attack

    Excessive air pressure is built up under the
    closed vocal cords

    Sudden release of this causes the speaker
    to speak in explosive voice

    Voice tires easily
Breathy voice

    Murmered voice

    Vocal cord vibrates normally but are held
    further apart then normal

    Excessive air escape occurs between the
    cords
Diplophonia

    Simultaneous production of sound of
    different pitches

    Common in UVCP

    Common in mass lesions of vocal folds
Pitch breaks

    Speaking in inappropriately high pitch

    Voice seems to be out of control

    Pt does not know what sound will come out
    next

    Common in puberphonia
Phonation break

    Complete cessation of phonation

    Temporary

    Commonly follows excessive use of voice
Tense phonation

    Appears like speech while lifing something
    heavy

    Laryngeal muscle tension

    Supralaryngeal muscle tension

    Loud, high pitched and harsh voice
Quantitative evaluation

    Sustaining a single tone at the fundamental
    frequency F0 (reduced in patients with
    vocal abuse, cord paralysis)

    Variations in amplitude (Shimmer) –
    variations due to decreased stability of
    vocal folds

    Variations in pitch (jitter) – correlates with
    degree of hoarseness
Stroboscopy

    Helps in dynamic assessment of vocal
    folds

    If frequency of strobe light is the same as
    fundamental voice frequency then vocal
    folds will not be seen in movement at all
Stroboscopy-what to look for

    Symmetry of movement

    Aperiodicity

    Glottic closure configuration

    Horizontal excursion
Management

    Reducing stress

    Reducing hyperfunctional compensatory
    mechanisms

    Breathing exercises

    Relaxation exercises
Cord injections

    Teflon

    Collagen

    Autologous fat
Teflon injection

    Indications ts– Irreversible unilateral vocal
    fold paralysis after a waiting period of 1 yr

    Contraindications – should not be used in
    pts with vocal fold atrophy, bowing
Teflon injection - Procedure

    No sedation

    Percutaneous approach (suitable)

    LA

    Performed under laryngoscopic guidance

    Anterior / lateral approaches are possible
Teflon injection (contd)

    In lateral approach surgeon pierces thyroid
    cartilage at the level of vocal folds

    In anterior approach needle is passed
    through cricothyroid membrane and angled
    supero laterally under endoscopic vision

    Teflon injection should be placed lateral to
    vocalis muscle without disturbing
    endolaryngeal mucosa
Transoral teflon injection

    Performed under DL scopy guidance

    Preferably under GA with jet ventilation

    The bevel of the needle should be held away
    from the mucosal edge

    Excessive pressure to anterior commissure to be
    avoided during the procedure as it would distort
    the cord

    Needle is ideally placed lateral to the vocal fold
    about 2 mm deep at the level of vocal process
Teflon injection - Limitations

    Irreversible

    If placed in a mobile cord mucosal wave is
    lost

    If the cord function gets back to normal
    after injection then results would be
    disastrous

    Useless in central causes of voice
    disorders
Collagen injection

    Modified bovine collagen is used (to minimize
    host response)

    Histologically it is similar to deep layer of lamina
    propria

    Gets assimilated into surrounding tissues by
    fibrobast invasion which replaces collagen with
    host collagen

    Collagen should be placed within lamina propria

    URI increases collage resorption
Autologous fat injection -
             Indications

    Vocal fold paralysis

    Vocal fold scarring

    Vocal fold atrophy

    Intubation injuries
Procedure

    Abdominal fat is used

    Cut into 1mm pieces, separated from
    connective tissue

    Rinsed with ringer lactate and methyl
    prednisolone solution

    Loaded in to a syringe

    Anterior, posterolateral and middle portions
    of the cord are injected

    50% over correction is aimed at
Advantages

    Reversible

    No reactions

    Immediate results are good
Type I thyroplasty - indications

    Unilateral / bilarateral vocal fold paralysis

    Incomplete glottal closure

    Vocal fold bowing
Contraindications

    Following irradiation

    In patients who have undergone
    hemilaryngectomy (thyroid lamina is a must
    to hold the prosthesis)
Type I Thyroplasty (Procedure)

    LA

    Horizontal incision over midportion of
    thyroid cartilage

    Window in thyroid ala created 8 mm
    posterior to ant. Commissure and 3 mm
    superior to its inferior border

    Inner perichondrial flaps created by inferior
    and posterior incisions
Contd

    Under laryngoscopic guidance
    measurement for medialization is taken

    Silastic block of appropriate size fashioned
    and inserted

    Voice checked on the table

    Cartilage from the window is ideally
    removed

    Inner perichondrium if preserved it is better
Complications

    Persistent dysphonia

    Implant migration

    Airway obstruction

    Hematoma formation

    Infections

    Useless to close large posterior gap
Arytenoid adduction - Indications

    To close a large posterior gap

    If the vocal folds are not at the same level
Procedure

    Horizontal skin crease incision at the level
    of vocal folds

    Posterior border of thyroid cartilage is
    exposed transecting strap muscles and
    detaching the inferior constrictor

    Recurrent laryngeal nerve should be
    identified

    Cricothyroid joint entered muscular process
    exposed
Contd

    PCA muscle identified and cut

    Nylon sutures placed over muscular
    process and pulled anteriorly through
    thyroid ala and anchored

    Pt is asked to phonate and the appropriate
    medialization is assessed
Reinnervation procedures

    Experimental

    Neuromuscular pedicle reinnervation

    Ansa cervicalis and recurrent laryngeal
    nerve anastomosis
Bilateral paralysis

    Does not cause stridor always

    Position of cord depends on fibrosis /
    synkinesis

    Treatment tailored to patient's needs
contd

    Tracheostomy – emergency

    Steroid injection (systemic)

    Adrenaline nebulization

    CPAP

    Intubation / ICU Care
contd

    Lateralizing procedures

    Chordectomy

    Arytenoidectomy
Thankyou

Vocal cord paralysis current concepts

  • 1.
    Vocal cord paralysiscurrent concepts Balasubramanian Thiagarajan
  • 2.
    What has changed?  Various hypothetical positions of vocal cord following paralysis – Not valid anymore  More simplistic classification of vocal fold position  All the theories accounting for vocal fold positions following paralysis are not accepted anymore
  • 3.
    Vocal fold positions  Abduction  Adduction  Midline
  • 4.
    Current theory accountingfor vocal vold position following vocal fold paralysis  Type of lesion  Pathology of lesion  Synkinesis  Fibrosis
  • 5.
    Types of vocalfold palsy  Unilateral recurrent laryngeal nerve palsy  Isolated unilateral superior laryngeal nerve palsy  Bilateral recurrent laryngeal nerve palsy  Bilateral complete paralysis of vocal folds
  • 6.
  • 7.
    Role of speechtherapy in URLP  Controversial  Does not hasten reinnervation  Helps in breath support  Helps psychologically  Swallowing therapy is useful in pts with swallowing difficulty
  • 8.
    Swallowing therapy  Swallowing while holding the breath  Push pull technique  Hand clasp technique
  • 9.
    Clinical examination (vocal)  Glottic fry  Hard glottal attacks  Breathy voice  Diplophonia  Pitch breaks  Phonation breaks  Tense phonation
  • 10.
    Glottic fry  Creaky voice  Cords vibrate slowly  Pt feels as if breath has run out while speaking
  • 11.
    Hard glottal attack  Excessive air pressure is built up under the closed vocal cords  Sudden release of this causes the speaker to speak in explosive voice  Voice tires easily
  • 12.
    Breathy voice  Murmered voice  Vocal cord vibrates normally but are held further apart then normal  Excessive air escape occurs between the cords
  • 13.
    Diplophonia  Simultaneous production of sound of different pitches  Common in UVCP  Common in mass lesions of vocal folds
  • 14.
    Pitch breaks  Speaking in inappropriately high pitch  Voice seems to be out of control  Pt does not know what sound will come out next  Common in puberphonia
  • 15.
    Phonation break  Complete cessation of phonation  Temporary  Commonly follows excessive use of voice
  • 16.
    Tense phonation  Appears like speech while lifing something heavy  Laryngeal muscle tension  Supralaryngeal muscle tension  Loud, high pitched and harsh voice
  • 17.
    Quantitative evaluation  Sustaining a single tone at the fundamental frequency F0 (reduced in patients with vocal abuse, cord paralysis)  Variations in amplitude (Shimmer) – variations due to decreased stability of vocal folds  Variations in pitch (jitter) – correlates with degree of hoarseness
  • 18.
    Stroboscopy  Helps in dynamic assessment of vocal folds  If frequency of strobe light is the same as fundamental voice frequency then vocal folds will not be seen in movement at all
  • 19.
    Stroboscopy-what to lookfor  Symmetry of movement  Aperiodicity  Glottic closure configuration  Horizontal excursion
  • 20.
    Management  Reducing stress  Reducing hyperfunctional compensatory mechanisms  Breathing exercises  Relaxation exercises
  • 21.
    Cord injections  Teflon  Collagen  Autologous fat
  • 22.
    Teflon injection  Indications ts– Irreversible unilateral vocal fold paralysis after a waiting period of 1 yr  Contraindications – should not be used in pts with vocal fold atrophy, bowing
  • 23.
    Teflon injection -Procedure  No sedation  Percutaneous approach (suitable)  LA  Performed under laryngoscopic guidance  Anterior / lateral approaches are possible
  • 24.
    Teflon injection (contd)  In lateral approach surgeon pierces thyroid cartilage at the level of vocal folds  In anterior approach needle is passed through cricothyroid membrane and angled supero laterally under endoscopic vision  Teflon injection should be placed lateral to vocalis muscle without disturbing endolaryngeal mucosa
  • 25.
    Transoral teflon injection  Performed under DL scopy guidance  Preferably under GA with jet ventilation  The bevel of the needle should be held away from the mucosal edge  Excessive pressure to anterior commissure to be avoided during the procedure as it would distort the cord  Needle is ideally placed lateral to the vocal fold about 2 mm deep at the level of vocal process
  • 26.
    Teflon injection -Limitations  Irreversible  If placed in a mobile cord mucosal wave is lost  If the cord function gets back to normal after injection then results would be disastrous  Useless in central causes of voice disorders
  • 27.
    Collagen injection  Modified bovine collagen is used (to minimize host response)  Histologically it is similar to deep layer of lamina propria  Gets assimilated into surrounding tissues by fibrobast invasion which replaces collagen with host collagen  Collagen should be placed within lamina propria  URI increases collage resorption
  • 28.
    Autologous fat injection- Indications  Vocal fold paralysis  Vocal fold scarring  Vocal fold atrophy  Intubation injuries
  • 29.
    Procedure  Abdominal fat is used  Cut into 1mm pieces, separated from connective tissue  Rinsed with ringer lactate and methyl prednisolone solution  Loaded in to a syringe  Anterior, posterolateral and middle portions of the cord are injected  50% over correction is aimed at
  • 30.
    Advantages  Reversible  No reactions  Immediate results are good
  • 31.
    Type I thyroplasty- indications  Unilateral / bilarateral vocal fold paralysis  Incomplete glottal closure  Vocal fold bowing
  • 32.
    Contraindications  Following irradiation  In patients who have undergone hemilaryngectomy (thyroid lamina is a must to hold the prosthesis)
  • 33.
    Type I Thyroplasty(Procedure)  LA  Horizontal incision over midportion of thyroid cartilage  Window in thyroid ala created 8 mm posterior to ant. Commissure and 3 mm superior to its inferior border  Inner perichondrial flaps created by inferior and posterior incisions
  • 34.
    Contd  Under laryngoscopic guidance measurement for medialization is taken  Silastic block of appropriate size fashioned and inserted  Voice checked on the table  Cartilage from the window is ideally removed  Inner perichondrium if preserved it is better
  • 35.
    Complications  Persistent dysphonia  Implant migration  Airway obstruction  Hematoma formation  Infections  Useless to close large posterior gap
  • 36.
    Arytenoid adduction -Indications  To close a large posterior gap  If the vocal folds are not at the same level
  • 37.
    Procedure  Horizontal skin crease incision at the level of vocal folds  Posterior border of thyroid cartilage is exposed transecting strap muscles and detaching the inferior constrictor  Recurrent laryngeal nerve should be identified  Cricothyroid joint entered muscular process exposed
  • 38.
    Contd  PCA muscle identified and cut  Nylon sutures placed over muscular process and pulled anteriorly through thyroid ala and anchored  Pt is asked to phonate and the appropriate medialization is assessed
  • 39.
    Reinnervation procedures  Experimental  Neuromuscular pedicle reinnervation  Ansa cervicalis and recurrent laryngeal nerve anastomosis
  • 40.
    Bilateral paralysis  Does not cause stridor always  Position of cord depends on fibrosis / synkinesis  Treatment tailored to patient's needs
  • 41.
    contd  Tracheostomy – emergency  Steroid injection (systemic)  Adrenaline nebulization  CPAP  Intubation / ICU Care
  • 42.
    contd  Lateralizing procedures  Chordectomy  Arytenoidectomy
  • 43.