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Dr. Sundar Dhungana
MS( ORL-HNS),3rd year
Resident
GMSMA of ENT-H & N Studies
MMC-TUTH,IOM
Road Map
 Electronystagmograph
y
 Calorie Test
Bithermal Caloric
test
 Computed Dynamic
Posturography
 Miscellaneous Tests
a) Rotatory Chair Test
b) Dynamic Visual Acuity
Test
c) Vestibular Evoked
Myogenic
Potential
d)Craniocorpography
• Most important diagnostic tool is careful history
• More than 70% of balance disorder is diagnosed by
history
• If clinical neurotological tests are combined -85%
• High-tech investigation modalities are necessary in about
10-15% only
• “In 80% of cases if one doesn’t have an idea of diagnosis
at the end of history, one is unlikely to have it at the end
of the examination and investigations”
Introduction
Objectives of investigations in vertiginous patients:
To estabished whether the patients has any definite vertiginous
problem and/or balance disorder
To establish and objectectively document the degree of functional
impairment
To localize the lesion topographically
To established etiological diagnosis
To established management protocol
Introduction contd…
Cont’d…
CNS
1- Cerebral cortex
2- Brainstem
3- Cerebellum
2-Vestibular
3-Proprioceptive
1- Visual
Rotation
Gravity
Ocular
Reflex
Postural
control
5
Introduction contd…
• Congenital nystagmus & squint rule out
• Stop taking for 3days :
 Medications that reduce vertigo.
 Sedatives and tranquilizers.
 Drinks containing alcohol.
 Stimulants, including foods that contain caffeine
(coffee, tea, cola, and chocolate)
Before test
• Monitors eye movements using electro-oculography
• Assess labyrinthine dysfunction and degree of
dysfunction
• Electroocolography types
Electronystagmography
Magnetic potentials (search coils)
Video-nystagmography
Infrared
• Corneoretinal potential
(CRP)-between the cornea
and the retina
• Retina is negatively
charged relative to the
cornea
• Electrical potential can be
measured -skin surface
electrodes
Advantages:
 Results of test quantified
Bithermal caloric test not accurately done without precise
stimulus control and response quantification provided by ENG
ENG provides documentation of results
 F/U of patients
 Medico-legal and workers compensation cases
Assesses each ear separately and can give side of lesion
localizing information
Limitations:
ENG tests only lateral semicircular canal
Traditional ENG testing using electrooculography relatively
insensitive to torsional nystagmus
Two of more common illnesses BPPV and Meniere’s disease
can have normal ENG despite “classic” symptomatology
ENG finding may be incidental and must be considered in light
of clinical history and physical examination
Videonystagmography
• computer-based system for
eye movement
• records eye movements
with digital video technology
using
– infrared illumination
– high-technology goggle
• visualization and recording
of eye movements
Videonystagmography contd..
Advantages:
• Easier and quicker than
using electrodes
• Only one calibration is
necessary
• Records rotational
nystagmus
Limitations:
• more expensive
• patients with
claustrophobia may not
tolerate
• patients with ptosis
• pupil-obscuring
eyelashes difficult to
test.
Magnetic search coil technique
• Involves patient sitting in a low-strength alternating
magnetic field
• soft contact lens in which a wire coil is embedded
• Motion of the coil of wire in the alternating magnetic field
induces a very small current in the wire
Magnetic search coil technique
contd…
Advantages:
• very precise
determination of eye
position in three
dimensions
• allows eye position to
be recorded very
rapidly
(500-1,000 times per sec).
Limitations:
• requires a
sophisticated
laboratory
• highly experienced
personnel
• based on the differing reflectance properties of the
iris compared to the sclera
• photocells of the eye remain stationary while the
edge of the iris moves with the eye
• light sensed by the photocells differs according to
eye position
Infrared oculography
Infrared oculography contd…
Advantages:
• Direct estimate of the eye
position as a function of
time can be calculated
Limitations:
• Bulk of the equipment
limits visual stimulation-
interference with eyelid
motion makes vertical
recording difficult
• Comprises of several
tests:
Test for sponataneous
nystagmus
Gaze nystagmus test
Saccade(caliberation) test
Pendulum tracking test
Optokinetic test
Positional and
posinoning test
Caloric test
Rotational test
Fistula test
• Records nystagmus when eyes open or
close
Right vertibular neuronitis
Brain stem tumour
• Nystagmus –look at apoint 30 degree away
from midline
Gaze evoked nystagmus:
Side effects of drugs: Anticonvulsants, alcohol
Multiple sclerosis
Myasthania gravis
Cerebellar atrophy
Test for gaze nystagmus in normal patient
Test for gaze nystagmus in patient suffering from cebellar
tumour
• tells us about the occulomotor system and
optic connections of the labrynth
• Patients concentrates on randomly moving target
• 80 targets (40 right, 40 left), amplitude (5-25 deg)
• Computer calculates
1. Peak velocity
2. Accuracy
3. Latency
Saccade(calibration) test
• Slow velocity saccade:
 Degenerative/metabolic CNS diseases
 Internuclear opthalmoplegia
 Cerebral hemisphere disturbances
 Drug intoxication
 Inattentive patient
• Abnormal fast velocity saccade:
 Orbital tumours
 Myasthenia gravis
Saccade(calibration) test
contd…
• Cerebellum plays an important role in determining
the accuracy of saccadic movements
• Inaccurate saccades, or ocular dysmetria are
classified as
– hypermetria (overshooting the target)
– hypometria (undershooting)
Saccade(calibration) test
contd…
• Saccadic latency abnormalities may be seen
in patients with
Abnormal vision
Parkinson's disease
Huntington's chorea
 Alzheimer's disease
Focal hemispheric lesions
Saccade(calibration) test
contd…
• Allows continuous tracking of moving objects
• Used to track targets at slower speeds and operates when
eyes move within orbit with head still
• VOR used when target move at faster speeds with
head moving
• Smooth pursuit system:
Computer-controlled visual target moves back and forth
(at frequencies from 0.2 to 0.7 Hz) in horizontal plane
Pursuit and Optokinetic test
contd…
• Normal individuals follow target smoothly in both
directions
at all target frequencies
• Deficits in smooth pursuit may from
Age
Medication
visual problems
attention deficit
lesions of brainstem, cerebellum, and occipitoparietal
junction
Pursuit and Optokinetic test
contd…
• Optokinetic Test
– images of whole visual
field fixed in retina and
prevent retinal slip.
Pursuit and Optokinetic test
contd…
Pursuit and Optokinetic test
contd…
Patient with a unilateral pursuit defect
• Determine if different head positions induce or modify vestibular
nystagmus
• Positional nystagmus
• Patient’s eye movements monitored while at least four
head positions
1) sitting
2) supine
3) head right (right ear down)
4) head left (left ear down
•Eye movements monitored in each position for about 20s with
visual and without visual fixation
Positional Test
Positional Test
• Positional nystagmus
i) intermittent
ii) persistent
• Nystagmus induced by ampullopetal stimulation
• Persistent positional nystagmus sustained as long as
head
position maintained
• Geotropgic, Ageotrophic
• Direction fixed or changing
• Eliminated or diminished with visual fixing
Positional Test
• Many patients complain of vertigo or dizziness with
head
movement
• Nystagmus differs from positional nystagmus
• Most frequently employed test
Dix-Hallpike maneuver
• If nystagmus elicited same maneuver repeated to
assess
Positioning Test contd…
• Torsional nystagmus
counterclockwise fast phase (right ear)
clockwise fast phase (left ear)
• Electronystagmography insensitive to torsional
component
• Horizontal: fast phase away from undermost ear
• Vertical: upbeating fast phase
Positioning Test contd…
Positioning Test contd…
Electronystagmographic tracing demonstrates horizontal and
vertical components of the nystagmus seen in BPPV
• Distinct features of positioning nystagmus
 Delayed Onset
 Always transient
 Accompanied by intense vertigo
 Fatigable
Positioning Test contd…
Positioning Test contd…
Bojrab-Calvert maneuver
Positioning Test contd…
Bithermal Caloric test
• Highly sensitive to unilateral
lesions of the peripheral
vestibular system
• Integrity of the lateral
semicircular canals and their
afferent pathways.
Caloric Test
Bithermal Caloric Test contd…
Bithermal Caloric Test
contd…
 Helps us to accurately calculate the percentage of canal
paresis
 Directional preponderance
• Tests integrity of lateral semicircular canals and their
afferent pathways
• Five characteristics of calorically induced nystagmus
1) Latency
2) Duration
3) Amplitude
4) Frequency
5) Velocity (most important)
• Slow-phase eye velocity equally strong in both directions
• Comparison of peak slow-phase eye velocity of cool and
warm caloric
Bithermal Caloric Test contd…
Bithermal Caloric Test contd…
• Unilateral Weakness (UW):
[(RC+RW)- (LC+LW)/RC+RW+LC+LW]X 100%
• Directional Preponderance (DP):
[(RC+LW)-(LC+RW)/RC+RW+LC+LW]x100%
• UW >20% and DP > 25% usually considered
significant
Bithermal Caloric Test contd…
• UW sign of decreased responsiveness of horizontal semicircular
canal or the ampullary nerve
• DP
 spontaneous nystagmus
 central sign indicating asymmetric sensitivities
 Meniere’s Disease
• Bithermal caloric test highly sensitive to U/L peripheral vestibular
dysfunction
• Relatively insensitive to bilateral dysfunction
• Rule of thumb: Caloric responses (warm response plus cool
response) of both ears fall below 12
degrees/second per side
Bithermal Caloric Test contd…
Bithermal Caloric Test contd…
• Posturography is quantitative balance test
• Assesses standing balance function under variety of
conditions
• Device consists of
platform capable of
moving back and forth
• Sensory organisation test
Motor control test
Computerized dynamic
posturography
Computerized dynamic posturography
contd...
1. Support fixed, eyes open,
visual fixed
2. Support fixed, eyes closed,
visual fixed
3. Support fixed, eyes open,
visual sway-referenced
4. Support swayed, eyes open,
visual fixed
5. Support swayed, eyes
closed, visual fixed
6. Support swayed, eyes open,
visual sway-referenced
Computerized dynamic posturography
contd...
Computerized dynamic posturography
contd...
Posturography test of a patient with total bilateral loss of
vestibular function
Use of Posturography
1) Planning and monitoring course of postural
rehabilitation
2) Documentation of postural responses in
suspected
a) malingering
b) exaggeration of disability for compensation
c) conversion disorder
Computerized dynamic posturography
contd...
• Another method of testing for VOR
• Passive rotational test
 Patient’s body is rotated without any movement
between the head and body
• Active rotational test
patient rotates his or her own head back and
forth while the body remains stationary
Rotational Test
• most useful
• passive test
• vertical axis through head
• LSCC in the plane of rotation
• Horizontal eye movements monitored
using
electro-oculography
Rotational chair test
The patient is seated in a chair so that the horizontal semicircular canals are
in the plane of rotation. Electro-oculography is used to monitor eye
Rotational chair test contd…
• Patient oscillated in sinusoidal fashion about vertical
axis at
various test frequencies (ranging from 0.01 to 01.28 Hz)
• Patient undergoes multiple cycles of oscillation at each
frequency
• Stimulus level delivered by rotary chair much greater
than that delivered in caloric testing(0.002 and 0.004 Hz)
• Computer compares head velocity and slow-phase eye
Rotational chair test contd…
Clinical Indications for Rotational Chair Testing
1. when the ENG is normal and oculomotor results are either
normal or observed abnormalities
2. when the ENG suggests a well compensated state despite the
presence of a clinically significant unilateral caloric weakness
3. when the caloric irrigations are below 12 degrees/s bilaterally
or when caloric irrigations cannot be performed
4. When a baseline measure is needed to follow the natural
history of the patient's disorder (MD)
Rotational chair test contd…
• Components of Rotary Chair Testing
 Gain : slow eye velocity/head velocity
 indicator of overall responsiveness
 Phase: temporal relationship between eye and
head velocities m
 measured in degrees
 greatest clinical significance
 increased phase lead implies peripheral
vestibular system dysfunction
 decreased phase lead suggest cerebellar lesion
Rotational chair test contd…
Symmetry: ratio of rightward to leftward slow- phase eye
velocity
asymmetry result from peripheral vestibular weakness or
contralateral excitory lesion
Rotational chair test contd…
Rotational chair test contd…
Normal RCT findings
• abnormalities seen on RCT can be
classified into four categories:
1. vestibular habituation and asymmetry
2. vestibular habituation
3. vestibular deficit
4. vestibular asymmetry
Rotational chair test contd…
Rotational chair test contd…
1.vestibular habituation and asymmetry
Rotational chair test contd…
2.vestibular habituation
Rotational chair test contd…
3.vestibular deficit
Rotational chair test contd…
4.vestibular asymmetry
Vestibular Autorotational Testing
• Active rotation test
• Patient actively shakes his/her head
from side to side with increasing
frequency
• Angular sensor is fixed to a
headband
• Advantages
– Portable
– relatively brief (18 sec) duration of
the test
– ability to test high-frequency (2-6
kHz) oscillations
• Test of inferior vestibular nerve
• Records myogenic potential in
cervical muscles(SCM) originating
from saccule
• Recorded by surface electrode
– Active electrode upper half SCM
– Reference electrode on sternal head
Vetibular Evoked Myogenic
Potential
– Alternate click of 105dB of 0.2
ms width is fed on test ear
and white noise of 30dB in
another ear for masking
– EMG is recorded
– Two trial in done for each ear
h
Vetibular Evoked Myogenic Potential
contd…
In healthy subjects
– Definite VEMP is recorded in 95% of cases
– Peak latency of positive and negative wave is 13.5
ms and 23ms respectively
In patients with dead vestibular labyrinths
– No VEMP recorded
h
Vetibular Evoked Myogenic Potential
contd…
h
Vetibular Evoked Myogenic Potential
contd…
Unilateral weakness for responses to the right VEMP
stimulus
• Test of VOR while
reading
acuity chart
• Examiner oscillates
patient’s head at 1 Hz;
new VA recorded
• 2 lines suspicious;>3
VOR grossly reduced
• Consist of graphically recording
patient’s head and body
movement
• Unterburger’s stepping
• Romberg’s test
Craniocorpography
References
• Glasscock-Shambaugh,Sugery of the Ear,6th edition
• Scott-Brown’s otorhinolaryngology head and neck surgery-
7th edition
• Scott-Brown’s otorhinolaryngology head and neck surgery-
6th edition
• Cummings otolaryngology head and neck surgery-5th
edition
• Diseases of Ear,Nose and Thoroat-PL Dhingra5th edition
• Ballenger’s Otorhinolaryngology Head and Neck Surgery-
16th edition
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Vestibular_tests_sundar in otolaryngology .pptx

  • 1. Dr. Sundar Dhungana MS( ORL-HNS),3rd year Resident GMSMA of ENT-H & N Studies MMC-TUTH,IOM
  • 2. Road Map  Electronystagmograph y  Calorie Test Bithermal Caloric test  Computed Dynamic Posturography  Miscellaneous Tests a) Rotatory Chair Test b) Dynamic Visual Acuity Test c) Vestibular Evoked Myogenic Potential d)Craniocorpography
  • 3. • Most important diagnostic tool is careful history • More than 70% of balance disorder is diagnosed by history • If clinical neurotological tests are combined -85% • High-tech investigation modalities are necessary in about 10-15% only • “In 80% of cases if one doesn’t have an idea of diagnosis at the end of history, one is unlikely to have it at the end of the examination and investigations” Introduction
  • 4. Objectives of investigations in vertiginous patients: To estabished whether the patients has any definite vertiginous problem and/or balance disorder To establish and objectectively document the degree of functional impairment To localize the lesion topographically To established etiological diagnosis To established management protocol Introduction contd…
  • 5. Cont’d… CNS 1- Cerebral cortex 2- Brainstem 3- Cerebellum 2-Vestibular 3-Proprioceptive 1- Visual Rotation Gravity Ocular Reflex Postural control 5 Introduction contd…
  • 6. • Congenital nystagmus & squint rule out • Stop taking for 3days :  Medications that reduce vertigo.  Sedatives and tranquilizers.  Drinks containing alcohol.  Stimulants, including foods that contain caffeine (coffee, tea, cola, and chocolate) Before test
  • 7. • Monitors eye movements using electro-oculography • Assess labyrinthine dysfunction and degree of dysfunction • Electroocolography types Electronystagmography Magnetic potentials (search coils) Video-nystagmography Infrared
  • 8. • Corneoretinal potential (CRP)-between the cornea and the retina • Retina is negatively charged relative to the cornea • Electrical potential can be measured -skin surface electrodes
  • 9. Advantages:  Results of test quantified Bithermal caloric test not accurately done without precise stimulus control and response quantification provided by ENG ENG provides documentation of results  F/U of patients  Medico-legal and workers compensation cases Assesses each ear separately and can give side of lesion localizing information
  • 10. Limitations: ENG tests only lateral semicircular canal Traditional ENG testing using electrooculography relatively insensitive to torsional nystagmus Two of more common illnesses BPPV and Meniere’s disease can have normal ENG despite “classic” symptomatology ENG finding may be incidental and must be considered in light of clinical history and physical examination
  • 11. Videonystagmography • computer-based system for eye movement • records eye movements with digital video technology using – infrared illumination – high-technology goggle • visualization and recording of eye movements
  • 12. Videonystagmography contd.. Advantages: • Easier and quicker than using electrodes • Only one calibration is necessary • Records rotational nystagmus Limitations: • more expensive • patients with claustrophobia may not tolerate • patients with ptosis • pupil-obscuring eyelashes difficult to test.
  • 13. Magnetic search coil technique • Involves patient sitting in a low-strength alternating magnetic field • soft contact lens in which a wire coil is embedded • Motion of the coil of wire in the alternating magnetic field induces a very small current in the wire
  • 14. Magnetic search coil technique contd… Advantages: • very precise determination of eye position in three dimensions • allows eye position to be recorded very rapidly (500-1,000 times per sec). Limitations: • requires a sophisticated laboratory • highly experienced personnel
  • 15. • based on the differing reflectance properties of the iris compared to the sclera • photocells of the eye remain stationary while the edge of the iris moves with the eye • light sensed by the photocells differs according to eye position Infrared oculography
  • 16. Infrared oculography contd… Advantages: • Direct estimate of the eye position as a function of time can be calculated Limitations: • Bulk of the equipment limits visual stimulation- interference with eyelid motion makes vertical recording difficult
  • 17. • Comprises of several tests: Test for sponataneous nystagmus Gaze nystagmus test Saccade(caliberation) test Pendulum tracking test Optokinetic test Positional and posinoning test Caloric test Rotational test Fistula test
  • 18. • Records nystagmus when eyes open or close
  • 21. • Nystagmus –look at apoint 30 degree away from midline Gaze evoked nystagmus: Side effects of drugs: Anticonvulsants, alcohol Multiple sclerosis Myasthania gravis Cerebellar atrophy
  • 22. Test for gaze nystagmus in normal patient
  • 23. Test for gaze nystagmus in patient suffering from cebellar tumour
  • 24. • tells us about the occulomotor system and optic connections of the labrynth
  • 25. • Patients concentrates on randomly moving target • 80 targets (40 right, 40 left), amplitude (5-25 deg) • Computer calculates 1. Peak velocity 2. Accuracy 3. Latency Saccade(calibration) test
  • 26. • Slow velocity saccade:  Degenerative/metabolic CNS diseases  Internuclear opthalmoplegia  Cerebral hemisphere disturbances  Drug intoxication  Inattentive patient • Abnormal fast velocity saccade:  Orbital tumours  Myasthenia gravis Saccade(calibration) test contd…
  • 27. • Cerebellum plays an important role in determining the accuracy of saccadic movements • Inaccurate saccades, or ocular dysmetria are classified as – hypermetria (overshooting the target) – hypometria (undershooting) Saccade(calibration) test contd…
  • 28. • Saccadic latency abnormalities may be seen in patients with Abnormal vision Parkinson's disease Huntington's chorea  Alzheimer's disease Focal hemispheric lesions Saccade(calibration) test contd…
  • 29. • Allows continuous tracking of moving objects • Used to track targets at slower speeds and operates when eyes move within orbit with head still • VOR used when target move at faster speeds with head moving • Smooth pursuit system: Computer-controlled visual target moves back and forth (at frequencies from 0.2 to 0.7 Hz) in horizontal plane Pursuit and Optokinetic test contd…
  • 30. • Normal individuals follow target smoothly in both directions at all target frequencies • Deficits in smooth pursuit may from Age Medication visual problems attention deficit lesions of brainstem, cerebellum, and occipitoparietal junction Pursuit and Optokinetic test contd…
  • 31. • Optokinetic Test – images of whole visual field fixed in retina and prevent retinal slip. Pursuit and Optokinetic test contd…
  • 32. Pursuit and Optokinetic test contd… Patient with a unilateral pursuit defect
  • 33. • Determine if different head positions induce or modify vestibular nystagmus • Positional nystagmus • Patient’s eye movements monitored while at least four head positions 1) sitting 2) supine 3) head right (right ear down) 4) head left (left ear down •Eye movements monitored in each position for about 20s with visual and without visual fixation Positional Test Positional Test
  • 34. • Positional nystagmus i) intermittent ii) persistent • Nystagmus induced by ampullopetal stimulation • Persistent positional nystagmus sustained as long as head position maintained • Geotropgic, Ageotrophic • Direction fixed or changing • Eliminated or diminished with visual fixing Positional Test
  • 35. • Many patients complain of vertigo or dizziness with head movement • Nystagmus differs from positional nystagmus • Most frequently employed test Dix-Hallpike maneuver • If nystagmus elicited same maneuver repeated to assess Positioning Test contd…
  • 36. • Torsional nystagmus counterclockwise fast phase (right ear) clockwise fast phase (left ear) • Electronystagmography insensitive to torsional component • Horizontal: fast phase away from undermost ear • Vertical: upbeating fast phase Positioning Test contd…
  • 37. Positioning Test contd… Electronystagmographic tracing demonstrates horizontal and vertical components of the nystagmus seen in BPPV
  • 38. • Distinct features of positioning nystagmus  Delayed Onset  Always transient  Accompanied by intense vertigo  Fatigable Positioning Test contd…
  • 41. Bithermal Caloric test • Highly sensitive to unilateral lesions of the peripheral vestibular system • Integrity of the lateral semicircular canals and their afferent pathways. Caloric Test
  • 43. Bithermal Caloric Test contd…  Helps us to accurately calculate the percentage of canal paresis  Directional preponderance • Tests integrity of lateral semicircular canals and their afferent pathways
  • 44. • Five characteristics of calorically induced nystagmus 1) Latency 2) Duration 3) Amplitude 4) Frequency 5) Velocity (most important) • Slow-phase eye velocity equally strong in both directions • Comparison of peak slow-phase eye velocity of cool and warm caloric Bithermal Caloric Test contd…
  • 46.
  • 47. • Unilateral Weakness (UW): [(RC+RW)- (LC+LW)/RC+RW+LC+LW]X 100% • Directional Preponderance (DP): [(RC+LW)-(LC+RW)/RC+RW+LC+LW]x100% • UW >20% and DP > 25% usually considered significant Bithermal Caloric Test contd…
  • 48. • UW sign of decreased responsiveness of horizontal semicircular canal or the ampullary nerve • DP  spontaneous nystagmus  central sign indicating asymmetric sensitivities  Meniere’s Disease • Bithermal caloric test highly sensitive to U/L peripheral vestibular dysfunction • Relatively insensitive to bilateral dysfunction • Rule of thumb: Caloric responses (warm response plus cool response) of both ears fall below 12 degrees/second per side Bithermal Caloric Test contd…
  • 50. • Posturography is quantitative balance test • Assesses standing balance function under variety of conditions • Device consists of platform capable of moving back and forth • Sensory organisation test Motor control test Computerized dynamic posturography
  • 52. 1. Support fixed, eyes open, visual fixed 2. Support fixed, eyes closed, visual fixed 3. Support fixed, eyes open, visual sway-referenced 4. Support swayed, eyes open, visual fixed 5. Support swayed, eyes closed, visual fixed 6. Support swayed, eyes open, visual sway-referenced Computerized dynamic posturography contd...
  • 53. Computerized dynamic posturography contd... Posturography test of a patient with total bilateral loss of vestibular function
  • 54. Use of Posturography 1) Planning and monitoring course of postural rehabilitation 2) Documentation of postural responses in suspected a) malingering b) exaggeration of disability for compensation c) conversion disorder Computerized dynamic posturography contd...
  • 55. • Another method of testing for VOR • Passive rotational test  Patient’s body is rotated without any movement between the head and body • Active rotational test patient rotates his or her own head back and forth while the body remains stationary Rotational Test
  • 56. • most useful • passive test • vertical axis through head • LSCC in the plane of rotation • Horizontal eye movements monitored using electro-oculography Rotational chair test
  • 57. The patient is seated in a chair so that the horizontal semicircular canals are in the plane of rotation. Electro-oculography is used to monitor eye Rotational chair test contd…
  • 58. • Patient oscillated in sinusoidal fashion about vertical axis at various test frequencies (ranging from 0.01 to 01.28 Hz) • Patient undergoes multiple cycles of oscillation at each frequency • Stimulus level delivered by rotary chair much greater than that delivered in caloric testing(0.002 and 0.004 Hz) • Computer compares head velocity and slow-phase eye Rotational chair test contd…
  • 59. Clinical Indications for Rotational Chair Testing 1. when the ENG is normal and oculomotor results are either normal or observed abnormalities 2. when the ENG suggests a well compensated state despite the presence of a clinically significant unilateral caloric weakness 3. when the caloric irrigations are below 12 degrees/s bilaterally or when caloric irrigations cannot be performed 4. When a baseline measure is needed to follow the natural history of the patient's disorder (MD) Rotational chair test contd…
  • 60. • Components of Rotary Chair Testing  Gain : slow eye velocity/head velocity  indicator of overall responsiveness  Phase: temporal relationship between eye and head velocities m  measured in degrees  greatest clinical significance  increased phase lead implies peripheral vestibular system dysfunction  decreased phase lead suggest cerebellar lesion Rotational chair test contd…
  • 61. Symmetry: ratio of rightward to leftward slow- phase eye velocity asymmetry result from peripheral vestibular weakness or contralateral excitory lesion Rotational chair test contd…
  • 62. Rotational chair test contd… Normal RCT findings
  • 63. • abnormalities seen on RCT can be classified into four categories: 1. vestibular habituation and asymmetry 2. vestibular habituation 3. vestibular deficit 4. vestibular asymmetry Rotational chair test contd…
  • 64. Rotational chair test contd… 1.vestibular habituation and asymmetry
  • 65. Rotational chair test contd… 2.vestibular habituation
  • 66. Rotational chair test contd… 3.vestibular deficit
  • 67. Rotational chair test contd… 4.vestibular asymmetry
  • 68. Vestibular Autorotational Testing • Active rotation test • Patient actively shakes his/her head from side to side with increasing frequency • Angular sensor is fixed to a headband • Advantages – Portable – relatively brief (18 sec) duration of the test – ability to test high-frequency (2-6 kHz) oscillations
  • 69. • Test of inferior vestibular nerve • Records myogenic potential in cervical muscles(SCM) originating from saccule • Recorded by surface electrode – Active electrode upper half SCM – Reference electrode on sternal head Vetibular Evoked Myogenic Potential
  • 70. – Alternate click of 105dB of 0.2 ms width is fed on test ear and white noise of 30dB in another ear for masking – EMG is recorded – Two trial in done for each ear h Vetibular Evoked Myogenic Potential contd…
  • 71. In healthy subjects – Definite VEMP is recorded in 95% of cases – Peak latency of positive and negative wave is 13.5 ms and 23ms respectively In patients with dead vestibular labyrinths – No VEMP recorded h Vetibular Evoked Myogenic Potential contd…
  • 72. h Vetibular Evoked Myogenic Potential contd… Unilateral weakness for responses to the right VEMP stimulus
  • 73. • Test of VOR while reading acuity chart • Examiner oscillates patient’s head at 1 Hz; new VA recorded • 2 lines suspicious;>3 VOR grossly reduced
  • 74. • Consist of graphically recording patient’s head and body movement • Unterburger’s stepping • Romberg’s test Craniocorpography
  • 75. References • Glasscock-Shambaugh,Sugery of the Ear,6th edition • Scott-Brown’s otorhinolaryngology head and neck surgery- 7th edition • Scott-Brown’s otorhinolaryngology head and neck surgery- 6th edition • Cummings otolaryngology head and neck surgery-5th edition • Diseases of Ear,Nose and Thoroat-PL Dhingra5th edition • Ballenger’s Otorhinolaryngology Head and Neck Surgery- 16th edition

Editor's Notes

  1. localise the lesion topographically-whether it is perpheral (rt/Lt) or central,the pathway between the vestibular labrynth and vestibular nuclei is conventionally termed as perpheral VS and vestibular area oc cortex-central To established management protocol-minisimizing discomfort and maximising functional capacity of patients
  2. Three arc neuron representation of the vestibuloocular reflex. Upon head rotation to the right (CW acc, clockwise acceleration), the hair cells on the 'leading ear' side are excited and increase their discharge rate, whereas the hair cells on the following ear are inhibited, thereby decreasing the discharge rate. The vestibular nuclei encode the increased discharge rate and redirect the excitation to the ipsilateral ocumolotor nuclei to contract the medial rectus of the right eye, while the contralateral abducens nucleus is triggered generating a contraction of the contralateral lateral rectus. Consequently the eyes are driven to the left to compensate for the head movement to the right. This is the essence of the VOR
  3. Electro-oculography (EOG).The cornea is relatively positively charged in comparison to the retina; thus, an electric potential exists between the two. Electrodes are placed around the eyes, and rotation of the eye brings the cornea closer to one electrode and the negatively charged retina closer to the other. The relative voltage difference provides the basis for EOG. By convention, rightward movement of the eye is recorded as an upward deflection on the electronystagmographic tracing
  4. -"of central vestibular neurons to inhibitory-excitatory stimuli or asymmetries in the inputs from these central vestibular neurons to extraocular motoneurons because the caloric stimulus is uncalibrated
  5. -"of central vestibular neurons to inhibitory-excitatory stimuli or asymmetries in the inputs from these central vestibular neurons to extraocular motoneurons because the caloric stimulus is uncalibrated
  6. helpful for later study and for teaching personnel and patients. This capacity is particularly useful in evaluating patients with benign paroxysmal positional vertigo (BPPV)—one of the most common vestibular abnormalities encountered. Videonystamographic tracings are clean with no drift, which improves the accuracy of analysis and interpretation. This technique is easier and quicker than using electrodes and only one calibration is necessary. There are limitations to the VNG that are noteworthy. Test equipment is more expensive, some patients with significant claustrophobia may not tolerate the sensation of confinement, and patients with ptosis, pupil-obscuring eyelashes, or other eye abnormalities may be difficult to test.
  7. helpful for later study and for teaching personnel and patients. This capacity is particularly useful in evaluating patients with benign paroxysmal positional vertigo (BPPV)—one of the most common vestibular abnormalities encountered. Videonystamographic tracings are clean with no drift, which improves the accuracy of analysis and interpretation. This technique is easier and quicker than using electrodes and only one calibration is necessary. There are limitations to the VNG that are noteworthy. Test equipment is more expensive, some patients with significant claustrophobia may not tolerate the sensation of confinement, and patients with ptosis, pupil-obscuring eyelashes, or other eye abnormalities may be difficult to test.
  8. Faraday*s lawinvolves the patient sitting in a low-strength, alternating magnetic field. The patient wears a soft contact lens in which a wire coil is embedded. The
  9. advantages of this method: it provides very precise determination of eye position in three dimensions and it allows eye position to be sampled and recorded very rapidly (500-1,000 times per sec). These features are responsible for the search coil technique providing the most accurate measurement of eye movements. The major disadvantage of the search coil technique is that it requires a sophisticated laboratory and highly experienced personnel
  10. Infrared oculography is based on the differing reflectance properties of the iris compared to the sclera and the fact that the photocells of the eye remain stationary while the edge of the iris moves with the eye. As a result, the light sensed by the photocells differs according to eye position.
  11. The advantage of this technique is that a direct estimate of the eye position as a function of time can be calculated. The disadvantages of this technique include the bulk of the equipment, which limits visual stimulation somewhat, and the interference with eyelid motion (eg, blink), which makes vertical recording difficult at times
  12. Fig:records first with eye open and than close.A-eye movement in vertical axis.-no vertical nystagmus B-eye movement in horizental axis-right beating nystagmus C-not a recording of eye movement tthis is a time marker and every second there is a vertical mark.
  13. Pt with right vertibular neuronitis-
  14. Test for gze nystagmus in normal person:there is no nystagmus in either left or right lateral position
  15. Test for gze nystagmus in pt suffering from cebellar tumour A right beating nystagmus in right lateral position
  16. Visual-Oculomotor function (Saccade, Smooth Persuit, Optokinetic test) ii) Abnormal eye movements (Gaze test, Positional test, Positioning test) iii) Vestibulo-Oculomotar function test (Bithermal caloric test)
  17. The purpose of the saccade system is to rapidly capture interesting visual targets in the periphery of the visual field onto the fovea. This quick foveating eye movement is a saccade The complete sequence often consists of 80 target jumps (40 to the right and 40 to the left), with amplitudes ranging from 5 to 25 degrees. After testing, the computer calculates three values for each saccade: peak velocity, accuracy, and latency.
  18. The purpose of the saccade system is to rapidly capture interesting visual targets in the periphery of the visual field onto the fovea. This quick foveating eye movement is a saccade
  19. cerebellum plays an important role in determining the accuracy of saccadic movements. Inaccurate saccades, or ocular dysmetria, are classified as hypermetria (overshooting the target) or hypometria (undershooting) and may be seen with cerebellardisease or brainstem disorders
  20. cerebellum plays an important role in determining the accuracy of saccadic movements. Inaccurate saccades, or ocular dysmetria, are classified as hypermetria (overshooting the target) or hypometria (undershooting) and may be seen with cerebellardisease or brainstem disorders
  21. Pursuit tracking,or the smooth pursuit system, allows continuous tracking of moving objects and works with the saccade system to maintain images on the fovea when the target is moving moving. The smooth pursuit system is used to track targets at slower speeds and operates when the eyes move within the orbit and the head is still. The VOR is used to maintain the stability of images on the fovea when the head is moving. The VOR is particularly important in maintaining stable gaze during rapid head movements
  22. After testing, the computer differentiates the eye position signal, calculates the gain of eye velocity with respect to target velocity separately for rightward and leftward tracking at each target frequency, and plots these data. Normal individuals are able to follow the target smoothly in both directions at all target frequencies. Deficits in smooth pursuit may result from age, medication, visual problems, attention deficit, or lesions of the brain stem, cerebellum, and occipitoparietal junction
  23. The function of optokinetic system to keep the images of whole visual field fixed in retina and prevent retinal slip. Stripe of drum or light in the bar is both moved in horizentl and vertical direction-Nystagmus Movement for 20 sec Asymmetrices in eye movement –CNS lesion The optokinetic pathways are subcortical, involving the accessory optic system. In humans, there is an overlap in function by neurons in the cortical and subcortical visual systems. The smooth pursuit system dominates the operation of the overall pursuit system.
  24. FIGURE 11-3 • The results of the tracking test in a patient with a unilateral pursuit defect. The patient was unable to follow the rightward-moving target smoothly and instead approximated its motion using successive saccades, producing a stair-step pattern on the eye movement tracing. Tracking of leftward-moving targets was normal. This patient's abnormality indicates an asymmetric central nervous system lesion involving the pursuit eye movement control system.
  25. The optokinetic pathways are subcortical, involving the accessory optic system. In humans, there is an overlap in function by neurons in the cortical and subcortical visual systems. The smooth pursuit system dominates the operation of the overall pursuit system
  26. nystagmusdifferent head positions,not head movement, elicit nystagmus
  27. Electronystagmographic tracing demonstrates horizontal and vertical components of the nystagmus seen in benign paroxysmal positional vertigo.
  28. Dix-Hallpike maneuver. The patient’s head is first turned to the left. The patient is then rapidly brought into the head-hanging position. Patients with benign paroxysmal positional vertigo typically demonstrate a geotropic, torsional nystagmus with the affected ear down. Frenzel’s lenses are used to prevent fixation-suppression. The test is repeated on the opposite side
  29. Bojrab-Calvert maneuver for benign paroxysmal positional vertigo. This positioning maneuver is useful in assessing positioning nystagmus in elderly or other individuals who cannot tolerate the neck extension position used in the Dix-Hallpike maneuver
  30. bithermal (Hallpike) caloric tests evaluate the integrity of the lateral semicircular canals and their afferent pathways. The patient is placed in the supine position with the head elevated 30 degrees, thereby placing the lateral semicircular canal in the vertical plane (Figure 11-8). Testing is properly done with the patient wearing Frenzel goggles to prevent fixation-suppression. Asking the patient to engage in mental tasks can also be helpful in releasing the nystagmus. Caloric testing may be performed with air or water. The correct position places the patient in the reclined position, 30 degrees elevated from the table, which places the horizontal canal in the vertical plane.
  31. Convective flow mechanism of the caloric response. Irrigation with warm or cold water (or air) results in a temperature gradient across the horizontal semicircular canal. With the horizontal canal oriented in the earth-vertical plane, gravity induces the convective flow of endolymph from the cooler area of the canal in which endolymph is more dense into the warmer area of the canal in which endolymph is less dense. For the warm caloric irrigation shown in this diagram, am ampullopetal deflection of the cupula results from this flow of endolymph. Vestibular-nerve afferents innervating the horizontal semicircular are excited, and a horizontal nystagmus with slow phase components directed toward the opposite ear is produced. A cold caloric stimulus results in an oppositely directed response with ampullofugal deflection to the cupula, inhibition of horizontal canal afferents, and a nystagmus with slow phase components directed toward the ear to which the cold caloric is applied.  (From Baloh RW, Honorubia V: Clinical neurophysiology of the vestibular system, ed 2, Philadelphia, 1990, FA Davis
  32. responses of the right ear with those of the left ear allows the examiner to determine whether a unilateral vestibular weakness exists
  33. responses of the right ear with those of the left ear allows the examiner to determine whether a unilateral vestibular weakness exists
  34. responses of the right ear with those of the left ear allows the examiner to determine whether a unilateral vestibular weakness exists
  35. -"Jongkee'sformula"ts
  36. -"of central vestibular neurons to inhibitory-excitatory stimuli or asymmetries in the inputs from these central vestibular neurons to extraocular motoneurons because the caloric stimulus is uncalibrated
  37. Caloric responses in a patient with unilateral labyrinthine hypofunction. Patient had no response in the left ear, although right ear responses were normal to warm and cold irrigations
  38. Evaluation of all sensory systems that provide information important for maintaining balance 1) vestibular 2) visual 3) somatosensory
  39. FIGURE 11-21 • Posturography test of a patient with total bilateral loss of vestibular function owing to ototoxicity. He has normal postural stability when tested under conditions 1 through 4 but marked instability on conditions 5 and 6, in which he had to rely solely on vestibular cues. This type of result may be seen in patients with acute unilateral peripheral vestibular lesions. Only rarely is it seen in patients with chronic unilateral vestibular dysfunction.
  40. Rotationaltests can be classified as either passive rotational tests, in which the patient’s body is rotated without any movement between the head and body, or as active rotational tests, in which the patient rotates his or her own head back and forth while the body remains stationary.
  41. Rotational tests can be classified as either passive rotational tests, in which the patient’s body is rotated without any movement between the head and body, or as active rotational tests, in which the patient rotates his or her own head back and forth while the body remains stationary.
  42. Phase, gain, and asymmetry values in relation to oscillation frequency for a patient with an acute right peripheral vestibular lesion. At lower oscillation frequencies, this patient shows progressively greater than normal phase leads. The patient also has a rightward asymmetry. This response pattern — abnormal low-frequency phase leads and high-frequency asymmetry — is routinely observed in patients with acute unilateral vestibular loss. The asymmetry is always toward the side of the loss
  43. Rotary chair testing stimulation generates right-beating nystagmus when the patient is moving rightward and leftbeating nystagmus when moving to the left
  44. Rotational chair testing stimulates both peripheral vestibular systems simultaneously; however, it may be helpful in determining the site of lesion in certain disorders. the patient's disorder (eg, possible early Meniere's disease
  45. Normal individuals,movement of the head to the right results in deviation of the eyes to the left. If the patient is rotated at a low frequency for a prolonged period of time, eye movement actually precedes the head movement
  46. Symmetry Symmetry is the ratio of rightward to leftward slow-phase eye velocity. This parameter gives information as to whether any bias is present in the system, favoring one direction over the other. Asymmetry may result from a peripheral vestibular weakness on the side of the larger slow-phase component or an excitatory lesion of the contralateral labyrinth. The purpose of the VOR is to produce eye movements that compensate for head movements, and the eye velocity is approximately 180 degrees out of phase with head velocity. When a normal individual is oscillated at low frequencies, slow-phase eye velocities exhibit progressively lower gains and are no longer exactly opposite in phase
  47. FIGURE 11-14 • Phase, gain, and asymmetry values in relation to oscillation frequency from a normal individual. Note that eye velocity signal is inverted during the analysis so that a phase angle of 180 degrees is expressed as a phase angle of 0 degrees. Phase leads become progressively larger and gains become progressively lower as oscillation frequency decreases. Symmetry values are approximately zero at all frequencies.
  48. FIGURE 11-15 • Phase, gain, and asymmetry values in relation to oscillation frequency for a patient with an acute right peripheral vestibular lesion. At lower oscillation frequencies, this patient shows progressively greater than normal phase leads. The patient also has a rightward asymmetry. This response pattern—abnormal low-frequency phase leads and high-frequency asymmetry—is routinely observed in patients with acute unilateral vestibular loss.The asymmetry is always toward the side of the loss.
  49. FIGURE 11-16 • Phase, gain, and asymmetry values in relation to oscillation frequency for a patient with a chronic left peripheral vestibular lesion (vestibular schwannoma). Electronystagmography showed a severe right caloric weakness. The rotational chair test shows greater than normal phase leads at lower test frequencies, reflecting a loss of velocity storage. This loss can be persistent, remaining for years following vestibular malfunction, although there is nearly always some recovery. The absence of tonic asymmetry in this individual illustrates the effect of vestibular compensation. If a peripheral vestibular lesion develops slowly, compensation is able to gradually rebalance the asymmetric input, preventing the vertigo and spontaneous nystagmus that would otherwise occur. Even when lesions develop suddenly, compensation quickly rebalances the tonic asymmetry over a period of days.
  50. FIGURE 11-17 • Phase, gain, and asymmetry values in relation to oscillation frequency for a patient with bilateral absence of caloric responses, showing absent responses at all oscillation frequencies. Phase values were not plotted owing to low response gains.
  51. FIGURE 11-18 • Phase, gain, and asymmetry values in relation to oscillation frequencies for a patient with bilateral absence of caloric responses, showing normal response gains at the higher frequencies.
  52. Vestibular autorotational testing is an active rotation test in which the patient actively shakes his/her head from side to side with increasing frequency. An angular sensor is fixed to a headband which is worn by the patient, and the eyes are evaluated with electro-oculography (Figure 11-19). Advantages of VAT over the other tests include portability of testing equipment, relatively brief (18 sec) duration of the test, and ability to test high-frequency (2-6 kHz) oscillations (when the VOR is active).
  53. Pt is made to sit in reclining chair in sound tret room head turnes to opposite side (making SCM contaction)
  54. Electromyography is recorded
  55. Electromyography is recorded
  56. FIGURE 11-25 • Unilateral weakness for responses to the right VEMP stimulus is demonstrated in this figure.
  57. Normal individuals,movement of the head to the right results in deviation of the eyes to the left. If the patient is rotated at alow frequency for a prolonged period of time, eye movement actually precedes the head movement
  58. 2 test are done in dark room in which there is a convex mirror with convex surface downwards fitted in roof. Pt is blindfolded and made to weare crown on head in wich 3 LED light are palced. Inbetween head and convex mirror –camera is place in adustable stand with lens directed upwards. Two extrem LED light are -40cm and at a scale to which the pts movement are compared for movement. Middle light –is the recording light.